KR101582448B1 - 진균 감염 치료를 위한 신규 약학적 조성물 - Google Patents

진균 감염 치료를 위한 신규 약학적 조성물 Download PDF

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KR101582448B1
KR101582448B1 KR1020157006206A KR20157006206A KR101582448B1 KR 101582448 B1 KR101582448 B1 KR 101582448B1 KR 1020157006206 A KR1020157006206 A KR 1020157006206A KR 20157006206 A KR20157006206 A KR 20157006206A KR 101582448 B1 KR101582448 B1 KR 101582448B1
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acid
composition
weight
pharmaceutical composition
component
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KR20150054824A (ko
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에바 칼슨
사하르 페이졸라흘 아스칼
피터 카우프만
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모베르그 파르마 아베
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Application filed by 모베르그 파르마 아베 filed Critical 모베르그 파르마 아베
Publication of KR20150054824A publication Critical patent/KR20150054824A/ko
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Assigned to 어드밴티스 헬쓰 아베 reassignment 어드밴티스 헬쓰 아베 권리의 전부이전등록 Assignors: 모베르그 파르마 아베
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/345—Alcohols containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020157006206A 2013-03-15 2014-02-28 진균 감염 치료를 위한 신규 약학적 조성물 Active KR101582448B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/GB2013/050654 WO2014140507A1 (en) 2013-03-15 2013-03-15 Pharmaceutical composition for the treatment of fungal infections
GBPCT/GB2013/050654 2013-03-15
PCT/GB2014/050604 WO2014140524A1 (en) 2013-03-15 2014-02-28 Pharmaceutical composition for the treatment of fungal infections

Publications (2)

Publication Number Publication Date
KR20150054824A KR20150054824A (ko) 2015-05-20
KR101582448B1 true KR101582448B1 (ko) 2016-01-04

Family

ID=48142011

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020157006206A Active KR101582448B1 (ko) 2013-03-15 2014-02-28 진균 감염 치료를 위한 신규 약학적 조성물

Country Status (26)

Country Link
US (2) US8987330B2 (https=)
EP (1) EP2777689B1 (https=)
JP (1) JP6503303B2 (https=)
KR (1) KR101582448B1 (https=)
CN (2) CN109394743A (https=)
BR (1) BR112015022590B8 (https=)
CA (1) CA2883613C (https=)
CY (1) CY1116559T1 (https=)
DK (1) DK2777689T3 (https=)
ES (1) ES2543957T3 (https=)
HR (1) HRP20150823T1 (https=)
HU (1) HUE026887T2 (https=)
IL (1) IL241175B (https=)
ME (1) ME02199B (https=)
MX (1) MX375135B (https=)
MY (1) MY176291A (https=)
PH (1) PH12015502073B1 (https=)
PL (1) PL2777689T3 (https=)
PT (1) PT2777689E (https=)
RS (1) RS54131B1 (https=)
SA (1) SA515361162B1 (https=)
SG (1) SG11201505763QA (https=)
SI (1) SI2777689T1 (https=)
SM (1) SMT201500214B (https=)
WO (2) WO2014140507A1 (https=)
ZA (1) ZA201505343B (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014140507A1 (en) 2013-03-15 2014-09-18 Moberg Pharma Ab Pharmaceutical composition for the treatment of fungal infections
KR101599260B1 (ko) * 2015-07-30 2016-03-03 (주)우신메딕스 조갑진균증의 예방 또는 치료용 약학 조성물 및 이의 제조방법
ITUB20153759A1 (it) * 2015-09-21 2017-03-21 Federica Livieri Composizione antifungina ad uso topico per il trattamento dell'onicomicosi e relativo metodo
US10258560B1 (en) 2016-08-08 2019-04-16 Marlinz Pharma, LLC Composition for topical treatment of nail conditions
US10543276B2 (en) 2016-08-08 2020-01-28 Marlinz Pharma, LLC Topical compositions
GB2554101B (en) * 2016-09-20 2021-05-05 Insense Ltd Composition for the treatment of a fungal infection
EP4552650A3 (en) * 2017-11-21 2025-08-13 Topix Pharmaceuticals, Inc. Methods and compositions for treatment of skin
WO2020131147A1 (en) * 2018-12-19 2020-06-25 Marlinz Pharma, LLC Topical compositions
US20220249859A1 (en) * 2021-02-09 2022-08-11 Scholl's Wellness Company Llc Formulation and device for cosmetic treatment of onychomycosis
US20240238227A1 (en) 2023-01-12 2024-07-18 Wooshin Labottach Co., Ltd. Pharmaceutical composition for preventing or treating onychomycosis and preparation method therefor

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5525635A (en) 1986-02-04 1996-06-11 Moberg; Sven Pharmaceutical compositions containing propylene glycol and/or polyethylene glycol and urea as active main components and use thereof
WO2003090736A1 (en) 2002-04-23 2003-11-06 Bradley Pharmaceuticals, Inc. Novel carbamide peroxide compositions for the treatment of dermatological disorders and methods for their use
WO2012110430A1 (en) 2011-02-10 2012-08-23 Moberg Derma Ab Novel composition for topical use on a nail

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4296130A (en) 1979-08-30 1981-10-20 Herschler R J Methylsulfonylmethane and methods of use
US4672078A (en) 1985-07-03 1987-06-09 Schering-Plough Corporation Urea stabilized with a lactone in various pharmaceutical and cosmetic preparations
SE462139B (sv) 1986-02-04 1990-05-14 Sven Moberg Farmaceutisk komposition, innehaallande propylenglykol och karbamid, foer behandling av bl.a. nagelsvamp och seborroiskt eksem
US5696164A (en) * 1994-12-22 1997-12-09 Johnson & Johnson Consumer Products, Inc. Antifungal treatment of nails
JP3820805B2 (ja) 1999-07-08 2006-09-13 株式会社ノエビア 皮膚外用剤
JP2003095914A (ja) * 2001-09-21 2003-04-03 Toyo Beauty Kk 尿素含有外用剤
US6986896B2 (en) * 2002-03-20 2006-01-17 Bradley Pharmaceuticals, Inc. Method of treating fungal conditions of the skin
US8158138B1 (en) * 2004-05-20 2012-04-17 Fougera Pharmaceuticals, Inc. Urea compositions and their methods of manufacture
JP4972895B2 (ja) * 2005-08-29 2012-07-11 大正製薬株式会社 尿素配合外用製剤
US8435500B2 (en) 2005-11-01 2013-05-07 L'oréal Nail whitening composition
EP2464334A4 (en) 2009-08-13 2014-03-26 Moberg Derma Ab COMPOSITIONS AND METHODS FOR TREATING FUNGAL INFECTION OF NAILS
WO2014140507A1 (en) 2013-03-15 2014-09-18 Moberg Pharma Ab Pharmaceutical composition for the treatment of fungal infections

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5525635A (en) 1986-02-04 1996-06-11 Moberg; Sven Pharmaceutical compositions containing propylene glycol and/or polyethylene glycol and urea as active main components and use thereof
WO2003090736A1 (en) 2002-04-23 2003-11-06 Bradley Pharmaceuticals, Inc. Novel carbamide peroxide compositions for the treatment of dermatological disorders and methods for their use
WO2012110430A1 (en) 2011-02-10 2012-08-23 Moberg Derma Ab Novel composition for topical use on a nail

Also Published As

Publication number Publication date
US9782372B2 (en) 2017-10-10
HK1208378A1 (en) 2016-03-04
CA2883613A1 (en) 2014-09-18
MY176291A (en) 2020-07-27
DK2777689T3 (da) 2015-06-22
RS54131B1 (sr) 2015-12-31
SA515361162B1 (ar) 2016-11-09
HUE026887T2 (en) 2016-07-28
CA2883613C (en) 2016-04-12
IL241175A0 (en) 2015-11-30
CN109394743A (zh) 2019-03-01
PL2777689T3 (pl) 2015-10-30
JP2016514121A (ja) 2016-05-19
ZA201505343B (en) 2017-06-28
CN104661639B (zh) 2019-06-28
SG11201505763QA (en) 2015-08-28
HRP20150823T1 (hr) 2015-09-11
WO2014140507A1 (en) 2014-09-18
US20150306052A1 (en) 2015-10-29
BR112015022590B8 (pt) 2023-03-21
MX375135B (es) 2025-03-06
BR112015022590B1 (pt) 2020-08-25
SI2777689T1 (sl) 2015-08-31
ME02199B (me) 2016-02-20
PH12015502073B1 (en) 2018-09-05
ES2543957T3 (es) 2015-08-26
IL241175B (en) 2019-10-31
CY1116559T1 (el) 2017-03-15
JP6503303B2 (ja) 2019-04-17
BR112015022590A2 (pt) 2017-07-18
PH12015502073A1 (en) 2016-01-25
SMT201500214B (it) 2015-10-30
MX2015012273A (es) 2016-01-25
KR20150054824A (ko) 2015-05-20
PT2777689E (pt) 2015-09-11
US20140275254A1 (en) 2014-09-18
US8987330B2 (en) 2015-03-24
CN104661639A (zh) 2015-05-27
EP2777689B1 (en) 2015-05-27
EP2777689A1 (en) 2014-09-17
WO2014140524A1 (en) 2014-09-18

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