CY1116559T1 - Νεα φαρμακευτικη συνθεση για την αγωγη μυκητιασικων λοιμωξεων - Google Patents
Νεα φαρμακευτικη συνθεση για την αγωγη μυκητιασικων λοιμωξεωνInfo
- Publication number
- CY1116559T1 CY1116559T1 CY20151100666T CY151100666T CY1116559T1 CY 1116559 T1 CY1116559 T1 CY 1116559T1 CY 20151100666 T CY20151100666 T CY 20151100666T CY 151100666 T CY151100666 T CY 151100666T CY 1116559 T1 CY1116559 T1 CY 1116559T1
- Authority
- CY
- Cyprus
- Prior art keywords
- component
- pharmaceutical composition
- components
- infections
- functional
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 208000015181 infectious disease Diseases 0.000 title 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 6
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 abstract 4
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 abstract 3
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 2
- 239000004202 carbamide Substances 0.000 abstract 2
- 150000002009 diols Chemical class 0.000 abstract 2
- 235000014655 lactic acid Nutrition 0.000 abstract 2
- 239000004310 lactic acid Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 150000007524 organic acids Chemical class 0.000 abstract 2
- 230000000699 topical effect Effects 0.000 abstract 2
- 208000010195 Onychomycosis Diseases 0.000 abstract 1
- XSTXAVWGXDQKEL-UHFFFAOYSA-N Trichloroethylene Chemical compound ClC=C(Cl)Cl XSTXAVWGXDQKEL-UHFFFAOYSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 208000026721 nail disease Diseases 0.000 abstract 1
- 201000005882 tinea unguium Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Birds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Emergency Medicine (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Παρέχονται φαρμακευτικές συνθέσεις κατάλληλες για τοπική εφαρμογή στον όνυχα για την αγωγή παθήσεων των ονύχων όπως είναι η ονυχομυκητίαση, περιλαμβάνοντας ένα συστατικό βάσει ουρίας, ένα συστατικό διόλης, όπως είναι η προπυλενγλυκόλη, ένα συστατικό οργανικού οξέος, όπως είναι το γαλακτικό οξύ, και ένα συστατικό τριόλης όπως μια γλυκερόλη. Παρέχονται περαιτέρω μέθοδοι βελτίωσης της σταθερότητας φύλαξης μιας φαρμακευτικής σύνθεσης κατάλληλης για τοπική εφαρμογή στο δέρμα και/ή στους όνυχες περιλαμβάνοντας τέτοια συστατικά βάσει ουρίας, συστατικά διόλης, συστατικά οργανικού οξέος, και, προαιρετικώς μια υδατική βάση, η οποία μέθοδος περιλαμβάνει την προσθήκη ενός συστατικού τριόλης, όπως μια γλυκερόλη, σε εκείνη την σύνθεση προ της εν λόγω φύλαξης.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/GB2013/050654 WO2014140507A1 (en) | 2013-03-15 | 2013-03-15 | Pharmaceutical composition for the treatment of fungal infections |
| EP14157373.3A EP2777689B1 (en) | 2013-03-15 | 2014-02-28 | New pharmaceutical composition for the treatment of fungal infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1116559T1 true CY1116559T1 (el) | 2017-03-15 |
Family
ID=48142011
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20151100666T CY1116559T1 (el) | 2013-03-15 | 2015-07-29 | Νεα φαρμακευτικη συνθεση για την αγωγη μυκητιασικων λοιμωξεων |
Country Status (27)
| Country | Link |
|---|---|
| US (2) | US8987330B2 (el) |
| EP (1) | EP2777689B1 (el) |
| JP (1) | JP6503303B2 (el) |
| KR (1) | KR101582448B1 (el) |
| CN (2) | CN104661639B (el) |
| BR (1) | BR112015022590B8 (el) |
| CA (1) | CA2883613C (el) |
| CY (1) | CY1116559T1 (el) |
| DK (1) | DK2777689T3 (el) |
| ES (1) | ES2543957T3 (el) |
| HK (1) | HK1208378A1 (el) |
| HR (1) | HRP20150823T1 (el) |
| HU (1) | HUE026887T2 (el) |
| IL (1) | IL241175B (el) |
| ME (1) | ME02199B (el) |
| MX (1) | MX2015012273A (el) |
| MY (1) | MY176291A (el) |
| PH (1) | PH12015502073B1 (el) |
| PL (1) | PL2777689T3 (el) |
| PT (1) | PT2777689E (el) |
| RS (1) | RS54131B1 (el) |
| SA (1) | SA515361162B1 (el) |
| SG (1) | SG11201505763QA (el) |
| SI (1) | SI2777689T1 (el) |
| SM (1) | SMT201500214B (el) |
| WO (2) | WO2014140507A1 (el) |
| ZA (1) | ZA201505343B (el) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014140507A1 (en) | 2013-03-15 | 2014-09-18 | Moberg Pharma Ab | Pharmaceutical composition for the treatment of fungal infections |
| KR101599260B1 (ko) * | 2015-07-30 | 2016-03-03 | (주)우신메딕스 | 조갑진균증의 예방 또는 치료용 약학 조성물 및 이의 제조방법 |
| ITUB20153759A1 (it) | 2015-09-21 | 2017-03-21 | Federica Livieri | Composizione antifungina ad uso topico per il trattamento dell'onicomicosi e relativo metodo |
| US10543276B2 (en) | 2016-08-08 | 2020-01-28 | Marlinz Pharma, LLC | Topical compositions |
| US10251858B1 (en) | 2016-08-08 | 2019-04-09 | Marlinz Pharma, LLC | Composition for treating fungal infections in nails |
| GB2554101B (en) * | 2016-09-20 | 2021-05-05 | Insense Ltd | Composition for the treatment of a fungal infection |
| EP3713583A4 (en) * | 2017-11-21 | 2021-06-30 | Topix Pharmaceuticals, Inc. | METHODS AND COMPOSITIONS FOR TREATMENT OF THE SKIN |
| SG11202105755PA (en) * | 2018-12-19 | 2021-07-29 | Marlinz Pharma Llc | Topical compositions |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4296130A (en) | 1979-08-30 | 1981-10-20 | Herschler R J | Methylsulfonylmethane and methods of use |
| US4672078A (en) | 1985-07-03 | 1987-06-09 | Schering-Plough Corporation | Urea stabilized with a lactone in various pharmaceutical and cosmetic preparations |
| SE462139B (sv) * | 1986-02-04 | 1990-05-14 | Sven Moberg | Farmaceutisk komposition, innehaallande propylenglykol och karbamid, foer behandling av bl.a. nagelsvamp och seborroiskt eksem |
| US5525635A (en) | 1986-02-04 | 1996-06-11 | Moberg; Sven | Pharmaceutical compositions containing propylene glycol and/or polyethylene glycol and urea as active main components and use thereof |
| US5696164A (en) * | 1994-12-22 | 1997-12-09 | Johnson & Johnson Consumer Products, Inc. | Antifungal treatment of nails |
| JP3820805B2 (ja) | 1999-07-08 | 2006-09-13 | 株式会社ノエビア | 皮膚外用剤 |
| JP2003095914A (ja) * | 2001-09-21 | 2003-04-03 | Toyo Beauty Kk | 尿素含有外用剤 |
| US6986896B2 (en) * | 2002-03-20 | 2006-01-17 | Bradley Pharmaceuticals, Inc. | Method of treating fungal conditions of the skin |
| US6573301B1 (en) * | 2002-04-23 | 2003-06-03 | Bradley Pharmaceuticals, Inc. | Carbamide peroxide compositions for the treatment of dermatological disorders and methods for their use |
| US8158138B1 (en) * | 2004-05-20 | 2012-04-17 | Fougera Pharmaceuticals, Inc. | Urea compositions and their methods of manufacture |
| JP4972895B2 (ja) * | 2005-08-29 | 2012-07-11 | 大正製薬株式会社 | 尿素配合外用製剤 |
| US8435500B2 (en) | 2005-11-01 | 2013-05-07 | L'oréal | Nail whitening composition |
| EP2464334A4 (en) | 2009-08-13 | 2014-03-26 | Moberg Derma Ab | COMPOSITIONS AND METHODS FOR TREATING FUNGAL INFECTION OF NAILS |
| WO2012110430A1 (en) * | 2011-02-10 | 2012-08-23 | Moberg Derma Ab | Novel composition for topical use on a nail |
| WO2014140507A1 (en) | 2013-03-15 | 2014-09-18 | Moberg Pharma Ab | Pharmaceutical composition for the treatment of fungal infections |
-
2013
- 2013-03-15 WO PCT/GB2013/050654 patent/WO2014140507A1/en active Application Filing
-
2014
- 2014-02-28 MX MX2015012273A patent/MX2015012273A/es active IP Right Grant
- 2014-02-28 WO PCT/GB2014/050604 patent/WO2014140524A1/en active Application Filing
- 2014-02-28 PT PT141573733T patent/PT2777689E/pt unknown
- 2014-02-28 ME MEP-2015-112A patent/ME02199B/me unknown
- 2014-02-28 BR BR112015022590A patent/BR112015022590B8/pt active IP Right Grant
- 2014-02-28 CN CN201480002472.9A patent/CN104661639B/zh active Active
- 2014-02-28 JP JP2015562293A patent/JP6503303B2/ja active Active
- 2014-02-28 RS RS20150488A patent/RS54131B1/en unknown
- 2014-02-28 HU HUE14157373A patent/HUE026887T2/en unknown
- 2014-02-28 PL PL14157373T patent/PL2777689T3/pl unknown
- 2014-02-28 SG SG11201505763QA patent/SG11201505763QA/en unknown
- 2014-02-28 ES ES14157373.3T patent/ES2543957T3/es active Active
- 2014-02-28 SI SI201430003T patent/SI2777689T1/sl unknown
- 2014-02-28 KR KR1020157006206A patent/KR101582448B1/ko active IP Right Grant
- 2014-02-28 MY MYPI2015703030A patent/MY176291A/en unknown
- 2014-02-28 EP EP14157373.3A patent/EP2777689B1/en active Active
- 2014-02-28 CA CA2883613A patent/CA2883613C/en active Active
- 2014-02-28 DK DK14157373.3T patent/DK2777689T3/da active
- 2014-02-28 CN CN201811088339.6A patent/CN109394743A/zh active Pending
- 2014-02-28 US US14/193,304 patent/US8987330B2/en active Active
-
2015
- 2015-01-29 US US14/609,142 patent/US9782372B2/en active Active
- 2015-07-24 ZA ZA2015/05343A patent/ZA201505343B/en unknown
- 2015-07-28 HR HRP20150823TT patent/HRP20150823T1/hr unknown
- 2015-07-29 CY CY20151100666T patent/CY1116559T1/el unknown
- 2015-09-03 IL IL24117515A patent/IL241175B/en active IP Right Grant
- 2015-09-10 SM SM201500214T patent/SMT201500214B/xx unknown
- 2015-09-11 PH PH12015502073A patent/PH12015502073B1/en unknown
- 2015-09-15 SA SA515361162A patent/SA515361162B1/ar unknown
- 2015-09-18 HK HK15109199.3A patent/HK1208378A1/xx unknown
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