KR101508022B1 - 메틸 ((1ｓ)-1-(((2ｓ)-2-(5-(4'-(2-((2ｓ)-1-((2ｓ)-2-((메톡시카르보닐)아미노)-3-메틸부타노일)-2-피롤리디닐)-1ｈ-이미다졸-5-일)-4-바이페닐릴)-1ｈ-이미다졸-2-일)-1-피롤리디닐)카르보닐)-2-메틸프로필)카르바메이트 디히드로클로라이드 염의 결정질 형태 - Google Patents

메틸 ((1ｓ)-1-(((2ｓ)-2-(5-(4'-(2-((2ｓ)-1-((2ｓ)-2-((메톡시카르보닐)아미노)-3-메틸부타노일)-2-피롤리디닐)-1ｈ-이미다졸-5-일)-4-바이페닐릴)-1ｈ-이미다졸-2-일)-1-피롤리디닐)카르보닐)-2-메틸프로필)카르바메이트 디히드로클로라이드 염의 결정질 형태 Download PDF

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KR101508022B1
KR101508022B1 KR20107002658A KR20107002658A KR101508022B1 KR 101508022 B1 KR101508022 B1 KR 101508022B1 KR 20107002658 A KR20107002658 A KR 20107002658A KR 20107002658 A KR20107002658 A KR 20107002658A KR 101508022 B1 KR101508022 B1 KR 101508022B1
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KR20100042641A (ko
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수진 김
치 가오
푸캉 양
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브리스톨-마이어스 스큅 컴퍼니
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR20107002658A 2007-08-08 2008-07-31 메틸 ((1ｓ)-1-(((2ｓ)-2-(5-(4'-(2-((2ｓ)-1-((2ｓ)-2-((메톡시카르보닐)아미노)-3-메틸부타노일)-2-피롤리디닐)-1ｈ-이미다졸-5-일)-4-바이페닐릴)-1ｈ-이미다졸-2-일)-1-피롤리디닐)카르보닐)-2-메틸프로필)카르바메이트 디히드로클로라이드 염의 결정질 형태 Expired - Fee Related KR101508022B1 (ko)

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US95459207P 2007-08-08 2007-08-08
US60/954,592 2007-08-08
PCT/US2008/071734 WO2009020828A1 (en) 2007-08-08 2008-07-31 Crystalline form of methyl ((1s)-1-(((2s)-2-(5-(4'-(2-((2s)-1-((2s)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-2-pyrrolidinyl)-1h-imidazol-5-yl)-4-biphenylyl)-1h-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamate dihydrochloride salt

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KR20100042641A KR20100042641A (ko) 2010-04-26
KR101508022B1 true KR101508022B1 (ko) 2015-04-08

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KR20107002658A Expired - Fee Related KR101508022B1 (ko) 2007-08-08 2008-07-31 메틸 ((1ｓ)-1-(((2ｓ)-2-(5-(4'-(2-((2ｓ)-1-((2ｓ)-2-((메톡시카르보닐)아미노)-3-메틸부타노일)-2-피롤리디닐)-1ｈ-이미다졸-5-일)-4-바이페닐릴)-1ｈ-이미다졸-2-일)-1-피롤리디닐)카르보닐)-2-메틸프로필)카르바메이트 디히드로클로라이드 염의 결정질 형태

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US (1) US8629171B2 (enExample)
EP (1) EP2183244B1 (enExample)
JP (1) JP5244179B2 (enExample)
KR (1) KR101508022B1 (enExample)
CN (1) CN101778840B (enExample)
AR (2) AR070016A1 (enExample)
AU (1) AU2008284100B2 (enExample)
BR (1) BRPI0815142B8 (enExample)
CA (1) CA2695729C (enExample)
CL (1) CL2008002354A1 (enExample)
CO (1) CO6160327A2 (enExample)
EA (1) EA018152B1 (enExample)
ES (1) ES2402791T3 (enExample)
IL (1) IL203684A (enExample)
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NZ (1) NZ583148A (enExample)
PE (1) PE20090940A1 (enExample)
TW (1) TWI359813B (enExample)
WO (1) WO2009020828A1 (enExample)
ZA (1) ZA201000843B (enExample)

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