KR101486931B1 - 해조류 추출물로부터 푸코이단을 정제하는 방법 - Google Patents

해조류 추출물로부터 푸코이단을 정제하는 방법 Download PDF

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KR101486931B1
KR101486931B1 KR1020097019831A KR20097019831A KR101486931B1 KR 101486931 B1 KR101486931 B1 KR 101486931B1 KR 1020097019831 A KR1020097019831 A KR 1020097019831A KR 20097019831 A KR20097019831 A KR 20097019831A KR 101486931 B1 KR101486931 B1 KR 101486931B1
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fucoidan
factor
composition
purified
acid
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KR20090127142A (ko
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패트릭 엔. 샤크리
제니퍼 바르-데이비드슨
스리니바사 프라사드
커크 존슨
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박스터 인터내쇼날 인코포레이티드
박스터 헬쓰케어 에스에이
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02—Algae
    • A61K36/03—Phaeophycota or phaeophyta (brown algae), e.g. Fucus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0036—Galactans; Derivatives thereof

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Virology (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020097019831A 2007-02-23 2008-02-01 해조류 추출물로부터 푸코이단을 정제하는 방법 Active KR101486931B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US89128707P 2007-02-23 2007-02-23
US60/891,287 2007-02-23
PCT/US2008/001425 WO2008103234A1 (en) 2007-02-23 2008-02-01 Process methods for fucoidan purification from seaweed extracts

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KR20090127142A KR20090127142A (ko) 2009-12-09
KR101486931B1 true KR101486931B1 (ko) 2015-01-27

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US (2) US8748595B2 (enExample)
EP (3) EP2121767B1 (enExample)
JP (1) JP5679663B2 (enExample)
KR (1) KR101486931B1 (enExample)
CN (2) CN101663326B (enExample)
ES (2) ES2683948T3 (enExample)
WO (1) WO2008103234A1 (enExample)

Cited By (1)

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KR20210075528A (ko) 2019-12-13 2021-06-23 한국프라임제약주식회사 비소가 저감된 해조류 추출물 및 이의 제조방법

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CN101663326B (zh) * 2007-02-23 2013-03-20 巴克斯特国际公司 从海藻提取物中纯化岩藻依聚糖的工艺方法
JP5739816B2 (ja) 2008-12-19 2015-06-24 バクスター・インターナショナル・インコーポレイテッドＢａｘｔｅｒ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｉｎｃｏｒｐ０Ｒａｔｅｄ Ｔｆｐｉインヒビターおよび使用法
JO3676B1 (ar) * 2009-07-27 2020-08-27 Arc Medical Devices Inc مركبات صيدلانية تضم فوكانات معدلة وطرق تتعلق بها
CN101659709B (zh) * 2009-09-18 2011-09-07 集美大学 岩藻聚糖的制备方法
US8632991B2 (en) * 2010-01-14 2014-01-21 Baxter International Inc. Methods and compositions for treating bleeding disorders
WO2011115712A2 (en) 2010-03-19 2011-09-22 Baxter International Inc Tfpi inhibitors and methods of use
CN102933192A (zh) * 2010-05-27 2013-02-13 勒蒂实验室有限公司 用于治疗通过编码角质化包膜成熟缺陷发生的疾病或病症的局部用药物或化妆品组合物
EP2588119A4 (en) * 2010-06-28 2014-01-08 Stemtech Internat Inc METHOD AND COMPOSITIONS FOR IMPROVING STRAIN CELL MOBILIZATION
EP2643356B1 (en) * 2010-11-23 2021-03-31 DuPont Nutrition USA, Inc. Process for isolating fucoidan and laminarin from live, harvested seaweed
CN103338780A (zh) * 2010-12-20 2013-10-02 韩国食品研究院 含有腔昆布提取物和黑昆布提取物的用于正向变构调节gabaa-苯二氮杂*受体的组合物和用于产生镇静催眠效果的组合物
CN102321052B (zh) * 2011-05-26 2013-08-21 天津市尖峰天然产物研究开发有限公司 综合利用海带提取纯化岩藻黄质和岩藻聚糖硫酸酯的方法
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CN102417549B (zh) * 2011-11-07 2013-07-24 沈阳科思高科技有限公司 一种基于微波化学的褐藻活性多糖的提取方法
KR20140091674A (ko) 2011-11-18 2014-07-22 스템테크 인터내셔널, 인크. 줄기 세포의 동원 및 증진을 강화하는 foti의 용도
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CN104698159B (zh) * 2015-03-10 2017-03-08 中国科学院苏州生物医学工程技术研究所 一种内毒素含量的检测方法
TWI743687B (zh) * 2016-06-27 2021-10-21 日商武田藥品工業股份有限公司 注射器穩定器
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KR101866906B1 (ko) * 2017-04-05 2018-06-12 한남대학교 산학협력단 후코이단의 추출방법
CN108641008B (zh) * 2018-05-11 2020-07-24 大连工业大学 裙带菜孢子叶提取岩藻聚糖硫酸酯及脱除重金属的方法
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CN112062871B (zh) * 2020-10-14 2022-06-28 福州海王福药制药有限公司 一种红藻多糖的制备方法
JP7770121B2 (ja) * 2021-06-30 2025-11-14 ポーラ化成工業株式会社 ヒアルロン酸受容体発現促進剤、これを含む皮膚外用剤並びに高分子ヒアルロン酸の保持効率向上方法
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Publication number Priority date Publication date Assignee Title
KR20210075528A (ko) 2019-12-13 2021-06-23 한국프라임제약주식회사 비소가 저감된 해조류 추출물 및 이의 제조방법

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EP2532686A1 (en) 2012-12-12
JP2010519383A (ja) 2010-06-03
US9234051B2 (en) 2016-01-12
CN102911281A (zh) 2013-02-06
EP2121767B1 (en) 2014-04-09
US20140328827A1 (en) 2014-11-06
EP2532686B1 (en) 2018-05-16
EP2121767A1 (en) 2009-11-25
CN102911281B (zh) 2015-04-15
US8748595B2 (en) 2014-06-10
JP5679663B2 (ja) 2015-03-04
US20100144667A1 (en) 2010-06-10
HK1135120A1 (en) 2010-05-28
EP3409694A1 (en) 2018-12-05
ES2683948T3 (es) 2018-09-28
WO2008103234A1 (en) 2008-08-28
ES2476250T3 (es) 2014-07-14
CN101663326B (zh) 2013-03-20
KR20090127142A (ko) 2009-12-09
CN101663326A (zh) 2010-03-03

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