JP5679663B2 - 海藻抽出物からのフコイダン精製のためのプロセスの方法 - Google Patents

海藻抽出物からのフコイダン精製のためのプロセスの方法 Download PDF

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JP5679663B2
JP5679663B2 JP2009550877A JP2009550877A JP5679663B2 JP 5679663 B2 JP5679663 B2 JP 5679663B2 JP 2009550877 A JP2009550877 A JP 2009550877A JP 2009550877 A JP2009550877 A JP 2009550877A JP 5679663 B2 JP5679663 B2 JP 5679663B2
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fucoidan
composition
factor
subject
acid
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JP2010519383A (ja
JP2010519383A5 (enExample
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パトリック エヌ． シャクリー，
パトリック エヌ． シャクリー，
ジェニファー バール−デイビッドソン，
ジェニファー バール−デイビッドソン，
スリニバサ プラサード，
スリニバサ プラサード，
ジョンソン，　カーク
カーク ジョンソン，
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Baxter Healthcare SA
Baxter International Inc
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Baxter International Inc
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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02—Algae
    • A61K36/03—Phaeophycota or phaeophyta (brown algae), e.g. Fucus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0036—Galactans; Derivatives thereof

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
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  • Hematology (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2009550877A 2007-02-23 2008-02-01 海藻抽出物からのフコイダン精製のためのプロセスの方法 Active JP5679663B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US89128707P 2007-02-23 2007-02-23
US60/891,287 2007-02-23
PCT/US2008/001425 WO2008103234A1 (en) 2007-02-23 2008-02-01 Process methods for fucoidan purification from seaweed extracts

Publications (3)

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JP2010519383A JP2010519383A (ja) 2010-06-03
JP2010519383A5 JP2010519383A5 (enExample) 2010-07-15
JP5679663B2 true JP5679663B2 (ja) 2015-03-04

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US (2) US8748595B2 (enExample)
EP (3) EP2121767B1 (enExample)
JP (1) JP5679663B2 (enExample)
KR (1) KR101486931B1 (enExample)
CN (2) CN101663326B (enExample)
ES (2) ES2683948T3 (enExample)
WO (1) WO2008103234A1 (enExample)

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JP5739816B2 (ja) 2008-12-19 2015-06-24 バクスター・インターナショナル・インコーポレイテッドＢａｘｔｅｒ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｉｎｃｏｒｐ０Ｒａｔｅｄ Ｔｆｐｉインヒビターおよび使用法
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US8632991B2 (en) * 2010-01-14 2014-01-21 Baxter International Inc. Methods and compositions for treating bleeding disorders
WO2011115712A2 (en) 2010-03-19 2011-09-22 Baxter International Inc Tfpi inhibitors and methods of use
CN102933192A (zh) * 2010-05-27 2013-02-13 勒蒂实验室有限公司 用于治疗通过编码角质化包膜成熟缺陷发生的疾病或病症的局部用药物或化妆品组合物
EP2588119A4 (en) * 2010-06-28 2014-01-08 Stemtech Internat Inc METHOD AND COMPOSITIONS FOR IMPROVING STRAIN CELL MOBILIZATION
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CN102321052B (zh) * 2011-05-26 2013-08-21 天津市尖峰天然产物研究开发有限公司 综合利用海带提取纯化岩藻黄质和岩藻聚糖硫酸酯的方法
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CN104698159B (zh) * 2015-03-10 2017-03-08 中国科学院苏州生物医学工程技术研究所 一种内毒素含量的检测方法
TWI743687B (zh) * 2016-06-27 2021-10-21 日商武田藥品工業股份有限公司 注射器穩定器
KR101721998B1 (ko) * 2016-08-16 2017-03-31 (주)한국바이오엔지니어링 이미, 이취, 및 염분 제거를 위한 반용매 정제기술이 적용된 후코이단 제조 방법
KR101866906B1 (ko) * 2017-04-05 2018-06-12 한남대학교 산학협력단 후코이단의 추출방법
CN108641008B (zh) * 2018-05-11 2020-07-24 大连工业大学 裙带菜孢子叶提取岩藻聚糖硫酸酯及脱除重金属的方法
US12186334B2 (en) 2018-07-27 2025-01-07 ARC Medical Inc. High-molecular-weight fucans for treating fibrous adhesions and other diseases and conditions
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CN112062871B (zh) * 2020-10-14 2022-06-28 福州海王福药制药有限公司 一种红藻多糖的制备方法
JP7770121B2 (ja) * 2021-06-30 2025-11-14 ポーラ化成工業株式会社 ヒアルロン酸受容体発現促進剤、これを含む皮膚外用剤並びに高分子ヒアルロン酸の保持効率向上方法
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KR101486931B1 (ko) 2015-01-27
EP2532686A1 (en) 2012-12-12
JP2010519383A (ja) 2010-06-03
US9234051B2 (en) 2016-01-12
CN102911281A (zh) 2013-02-06
EP2121767B1 (en) 2014-04-09
US20140328827A1 (en) 2014-11-06
EP2532686B1 (en) 2018-05-16
EP2121767A1 (en) 2009-11-25
CN102911281B (zh) 2015-04-15
US8748595B2 (en) 2014-06-10
US20100144667A1 (en) 2010-06-10
HK1135120A1 (en) 2010-05-28
EP3409694A1 (en) 2018-12-05
ES2683948T3 (es) 2018-09-28
WO2008103234A1 (en) 2008-08-28
ES2476250T3 (es) 2014-07-14
CN101663326B (zh) 2013-03-20
KR20090127142A (ko) 2009-12-09
CN101663326A (zh) 2010-03-03

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