KR101422286B1 - 결합 분자 - Google Patents

결합 분자 Download PDF

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Publication number
KR101422286B1
KR101422286B1 KR1020077004055A KR20077004055A KR101422286B1 KR 101422286 B1 KR101422286 B1 KR 101422286B1 KR 1020077004055 A KR1020077004055 A KR 1020077004055A KR 20077004055 A KR20077004055 A KR 20077004055A KR 101422286 B1 KR101422286 B1 KR 101422286B1
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South Korea
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heavy chain
region
antibody
binding
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Expired - Lifetime
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Korean (ko)
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KR20070050927A (ko
Inventor
로저 킹돈 크레이그
프랭클린 게라르두스 그로스벨드
리차드 빌헬름 얀센스
두브라브카 드라베크
Original Assignee
에라스무스 유니버시티 메디컬 센터 로테르담
로저 킹돈 크레이그
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35431831&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR101422286(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0416392A external-priority patent/GB2416768A/en
Priority claimed from GB0511881A external-priority patent/GB0511881D0/en
Application filed by 에라스무스 유니버시티 메디컬 센터 로테르담, 로저 킹돈 크레이그 filed Critical 에라스무스 유니버시티 메디컬 센터 로테르담
Publication of KR20070050927A publication Critical patent/KR20070050927A/ko
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Publication of KR101422286B1 publication Critical patent/KR101422286B1/ko
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
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    • C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1054—Lentiviridae, e.g. HIV, FIV, SIV gag-pol, e.g. p17, p24
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036—Retroviridae, e.g. leukemia viruses
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    • C07K16/1063—Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
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    • C07K16/1228—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K16/1232—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia from Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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    • C07K—PEPTIDES
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    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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    • C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
    • C—CHEMISTRY; METALLURGY
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    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/73—Fusion polypeptide containing domain for protein-protein interaction containing coiled-coiled motif (leucine zippers)

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  • Engineering & Computer Science (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Zoology (AREA)
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  • Wood Science & Technology (AREA)
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  • Communicable Diseases (AREA)
  • General Engineering & Computer Science (AREA)
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KR1020077004055A 2004-07-22 2005-07-22 결합 분자 Expired - Lifetime KR101422286B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0416392.9 2004-07-22
GB0416392A GB2416768A (en) 2004-07-22 2004-07-22 Heavy chain immunoglobulin complexes
GB0511881A GB0511881D0 (en) 2005-06-10 2005-06-10 Binding molecules
GB0511881.5 2005-06-10
PCT/GB2005/002892 WO2006008548A2 (en) 2004-07-22 2005-07-22 Binding molecules

Related Child Applications (3)

Application Number Title Priority Date Filing Date
KR1020107026625A Division KR101151957B1 (ko) 2004-07-22 2005-07-22 결합 분자
KR1020127016031A Division KR101443473B1 (ko) 2004-07-22 2005-07-22 Ｖh 결합 영역의 분리 방법
KR1020117019563A Division KR101457753B1 (ko) 2004-07-22 2005-07-22 결합 분자

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Publication Number Publication Date
KR20070050927A KR20070050927A (ko) 2007-05-16
KR101422286B1 true KR101422286B1 (ko) 2014-07-23

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KR1020077004055A Expired - Lifetime KR101422286B1 (ko) 2004-07-22 2005-07-22 결합 분자
KR1020117019563A Ceased KR101457753B1 (ko) 2004-07-22 2005-07-22 결합 분자
KR1020107026625A Expired - Lifetime KR101151957B1 (ko) 2004-07-22 2005-07-22 결합 분자
KR1020127016031A Expired - Lifetime KR101443473B1 (ko) 2004-07-22 2005-07-22 Ｖh 결합 영역의 분리 방법

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KR1020117019563A Ceased KR101457753B1 (ko) 2004-07-22 2005-07-22 결합 분자
KR1020107026625A Expired - Lifetime KR101151957B1 (ko) 2004-07-22 2005-07-22 결합 분자
KR1020127016031A Expired - Lifetime KR101443473B1 (ko) 2004-07-22 2005-07-22 Ｖh 결합 영역의 분리 방법

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Country Link
US (7) US20090285805A1 (enExample)
EP (6) EP1978032A3 (enExample)
JP (3) JP2008512987A (enExample)
KR (4) KR101422286B1 (enExample)
CN (2) CN102659941B (enExample)
AU (2) AU2005263994B2 (enExample)
BR (1) BRPI0513577A (enExample)
CA (1) CA2580336C (enExample)
CY (2) CY1115762T1 (enExample)
DK (3) DK1864998T4 (enExample)
ES (3) ES2635497T3 (enExample)
HU (1) HUE034335T2 (enExample)
LT (1) LT2311874T (enExample)
MX (2) MX2007000921A (enExample)
PL (2) PL1776383T3 (enExample)
PT (2) PT1776383E (enExample)
RU (1) RU2398882C2 (enExample)
SG (1) SG188080A1 (enExample)
SI (2) SI2311874T1 (enExample)
WO (1) WO2006008548A2 (enExample)
ZA (3) ZA200701186B (enExample)

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US7754208B2 (en) 2001-01-17 2010-07-13 Trubion Pharmaceuticals, Inc. Binding domain-immunoglobulin fusion proteins
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