KR101382083B1 - 상호침투성 망상구조, 및 관련 방법 및 조성물 - Google Patents

상호침투성 망상구조, 및 관련 방법 및 조성물 Download PDF

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KR101382083B1
KR101382083B1 KR1020087008620A KR20087008620A KR101382083B1 KR 101382083 B1 KR101382083 B1 KR 101382083B1 KR 1020087008620 A KR1020087008620 A KR 1020087008620A KR 20087008620 A KR20087008620 A KR 20087008620A KR 101382083 B1 KR101382083 B1 KR 101382083B1
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collagen
network
polymer
ipn
corneal
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KR20080065973A (ko
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메이 그리피쓰
펭푸 리
웬구앙 리우
메대드 라팻
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오타와 하스피털 리서치 인스티튜트
유니버시티 오브 오타와
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L101/00—Compositions of unspecified macromolecular compounds
    • C08L101/12—Compositions of unspecified macromolecular compounds characterised by physical features, e.g. anisotropy, viscosity or electrical conductivity
    • C08L101/14—Compositions of unspecified macromolecular compounds characterised by physical features, e.g. anisotropy, viscosity or electrical conductivity the macromolecular compounds being water soluble or water swellable, e.g. aqueous gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F283/00—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F283/00—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G
    • C08F283/06—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G on to polyethers, polyoxymethylenes or polyacetals
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00—Macromolecular products derived from proteins
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/24—Crosslinking, e.g. vulcanising, of macromolecules
    • C08J3/246—Intercrosslinking of at least two polymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L33/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • C08L33/04—Homopolymers or copolymers of esters
    • C08L33/14—Homopolymers or copolymers of esters of esters containing halogen, nitrogen, sulfur, or oxygen atoms in addition to the carboxy oxygen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/04—Alginic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof
    • C08L89/04—Products derived from waste materials, e.g. horn, hoof or hair
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof
    • C08L89/04—Products derived from waste materials, e.g. horn, hoof or hair
    • C08L89/06—Products derived from waste materials, e.g. horn, hoof or hair derived from leather or skin, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2300/00—Characterised by the use of unspecified polymers
    • C08J2300/16—Biodegradable polymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2205/00—Polymer mixtures characterised by other features
    • C08L2205/04—Polymer mixtures characterised by other features containing interpenetrating networks

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Inorganic Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Prostheses (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Graft Or Block Polymers (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicinal Preparation (AREA)
KR1020087008620A 2005-09-09 2006-09-11 상호침투성 망상구조, 및 관련 방법 및 조성물 Expired - Fee Related KR101382083B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US71541105P 2005-09-09 2005-09-09
US60/715,411 2005-09-09
PCT/CA2006/001520 WO2007028258A2 (en) 2005-09-09 2006-09-11 Interpenetrating networks, and related methods and compositions

Publications (2)

Publication Number Publication Date
KR20080065973A KR20080065973A (ko) 2008-07-15
KR101382083B1 true KR101382083B1 (ko) 2014-04-10

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KR1020087008620A Expired - Fee Related KR101382083B1 (ko) 2005-09-09 2006-09-11 상호침투성 망상구조, 및 관련 방법 및 조성물

Country Status (9)

Country Link
US (1) US20080317818A1 (enExample)
EP (2) EP1934289A4 (enExample)
JP (2) JP2009507110A (enExample)
KR (1) KR101382083B1 (enExample)
CN (1) CN101305052B (enExample)
AU (1) AU2006289625B2 (enExample)
CA (1) CA2621824C (enExample)
SG (2) SG10201807556TA (enExample)
WO (1) WO2007028258A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101944008B1 (ko) * 2017-09-18 2019-01-30 (주) 제이씨바이오 히알루론산을 포함하는 투명 하이드로겔 막 및 이를 이용한 콘택트렌즈

Families Citing this family (192)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6302875B1 (en) 1996-10-11 2001-10-16 Transvascular, Inc. Catheters and related devices for forming passageways between blood vessels or other anatomical structures
US8150519B2 (en) 2002-04-08 2012-04-03 Ardian, Inc. Methods and apparatus for bilateral renal neuromodulation
US20070129761A1 (en) 2002-04-08 2007-06-07 Ardian, Inc. Methods for treating heart arrhythmia
US7617005B2 (en) 2002-04-08 2009-11-10 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US20070135875A1 (en) 2002-04-08 2007-06-14 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US9636174B2 (en) 2002-04-08 2017-05-02 Medtronic Ardian Luxembourg S.A.R.L. Methods for therapeutic renal neuromodulation
US20080213331A1 (en) 2002-04-08 2008-09-04 Ardian, Inc. Methods and devices for renal nerve blocking
JP2006508709A (ja) 2002-09-13 2006-03-16 オキュラー サイエンシス インコーポレイテッド 視力を向上させる器具及び方法
ES2564694T3 (es) 2003-09-12 2016-03-28 Vessix Vascular, Inc. Sistema de remodelación y / o ablación excéntrica seleccionable de material ateroesclerótico
CA2566961A1 (en) 2004-05-20 2005-12-08 Coopervision, Inc. Corneal onlays and wavefront aberration correction to enhance vision
US9713730B2 (en) 2004-09-10 2017-07-25 Boston Scientific Scimed, Inc. Apparatus and method for treatment of in-stent restenosis
US8396548B2 (en) 2008-11-14 2013-03-12 Vessix Vascular, Inc. Selective drug delivery in a lumen
US7909867B2 (en) * 2004-10-05 2011-03-22 The Board Of Trustees Of The Leland Stanford Junior University Interpenetrating polymer network hydrogel corneal prosthesis
US20090088846A1 (en) 2007-04-17 2009-04-02 David Myung Hydrogel arthroplasty device
US7857849B2 (en) * 2004-10-05 2010-12-28 The Board Of Trustees Of The Leland Stanford Junior Iniversity Artificial corneal implant
US7857447B2 (en) * 2004-10-05 2010-12-28 The Board Of Trustees Of The Leland Stanford Junior University Interpenetrating polymer network hydrogel contact lenses
WO2006063199A2 (en) 2004-12-09 2006-06-15 The Foundry, Inc. Aortic valve repair
US8019435B2 (en) 2006-05-02 2011-09-13 Boston Scientific Scimed, Inc. Control of arterial smooth muscle tone
US20080089923A1 (en) 2006-09-29 2008-04-17 Burkstrand Michael J Biodegradable ocular implants and methods for treating ocular conditions
WO2008049087A2 (en) 2006-10-18 2008-04-24 Minnow Medical, Inc. System for inducing desirable temperature effects on body tissue
ES2560006T3 (es) 2006-10-18 2016-02-17 Vessix Vascular, Inc. Inducción de efectos de temperatura deseables sobre tejido corporal
EP2076193A4 (en) 2006-10-18 2010-02-03 Minnow Medical Inc MATCHED RF-ENERGY AND ELECTRO-TISSUE CHARACTERIZATION FOR THE SELECTIVE TREATMENT OF TARGET TISSUE
CA2705369C (fr) * 2007-11-14 2016-10-18 Ma.I.A Woundcare Biomateriau permettant la delivrance controlee d'actifs
FR2924615B1 (fr) * 2007-12-07 2010-01-22 Vivacy Lab Hydrogel cohesif biodegradable.
US20090182068A1 (en) * 2008-01-14 2009-07-16 Yuwen Liu Polymerizable Contact Lens Formulations and Contact Lenses Obtained Therefrom
US20120209396A1 (en) 2008-07-07 2012-08-16 David Myung Orthopedic implants having gradient polymer alloys
JP5722773B2 (ja) 2008-08-05 2015-05-27 バイオミメディカ インコーポレイテッド ポリウレタングラフト化ヒドロゲル
JP5271632B2 (ja) * 2008-08-08 2013-08-21 国立大学法人金沢大学 神経細胞死抑制作用をもつｖｉ型コラーゲン
KR20110104504A (ko) 2008-11-17 2011-09-22 미노우 메디컬, 인코포레이티드 조직 토폴로지의 지식 여하에 따른 에너지의 선택적 축적
FR2938544B1 (fr) * 2008-11-20 2011-01-21 Univ Cergy Pontoise Materiaux sous forme de reseaux interpenetres de polymeres associant un gel de fibrine et un reseau de polyethylene glycol
KR100994747B1 (ko) * 2008-12-31 2010-12-07 주식회사 인터로조 습윤성이 향상된 하이드로젤 콘택트렌즈
EP2398577A2 (en) * 2009-02-19 2011-12-28 Bonner, Alex Garfield Porous interpenetrating polymer network
US20130085571A1 (en) * 2009-05-14 2013-04-04 Anja Mueller Composition and method of preparation of polysaccharide gel-based artificial, biodegradable skin scaffolds
WO2011005974A2 (en) * 2009-07-08 2011-01-13 Northwestern University Interpenetrating biomaterial matrices and uses thereof
EP2481399B1 (en) * 2009-08-18 2015-11-25 Tohoku University Sustained drug delivery system
US9987225B2 (en) 2009-09-30 2018-06-05 Ottawa Hospital Research Institute Crosslinked hydrogels and related method of preparation
CN103068330B (zh) 2010-04-09 2016-06-29 Vessix血管股份有限公司 用于治疗组织的功率发生和控制装置
US9192790B2 (en) 2010-04-14 2015-11-24 Boston Scientific Scimed, Inc. Focused ultrasonic renal denervation
US8473067B2 (en) 2010-06-11 2013-06-25 Boston Scientific Scimed, Inc. Renal denervation and stimulation employing wireless vascular energy transfer arrangement
CN101891946B (zh) * 2010-07-17 2012-07-04 厦门大学 一种具有dn-l结构的增强生物水凝胶及其制备方法
US9408661B2 (en) 2010-07-30 2016-08-09 Patrick A. Haverkost RF electrodes on multiple flexible wires for renal nerve ablation
US9358365B2 (en) 2010-07-30 2016-06-07 Boston Scientific Scimed, Inc. Precision electrode movement control for renal nerve ablation
US9084609B2 (en) 2010-07-30 2015-07-21 Boston Scientific Scime, Inc. Spiral balloon catheter for renal nerve ablation
US9463062B2 (en) 2010-07-30 2016-10-11 Boston Scientific Scimed, Inc. Cooled conductive balloon RF catheter for renal nerve ablation
US9155589B2 (en) 2010-07-30 2015-10-13 Boston Scientific Scimed, Inc. Sequential activation RF electrode set for renal nerve ablation
WO2012027678A1 (en) 2010-08-27 2012-03-01 Biomimedica, Inc. Hydrophobic and hydrophilic interpenetrating polymer networks derived from hydrophobic polymers and methods of preparing the same
CN101942198B (zh) * 2010-09-03 2012-05-23 东华大学 多孔硅水凝胶互穿网络（ipn）膜的制备方法
EP2622594B1 (en) 2010-10-01 2018-08-22 Applied Medical Resources Corporation Portable laparoscopic trainer
US8974451B2 (en) 2010-10-25 2015-03-10 Boston Scientific Scimed, Inc. Renal nerve ablation using conductive fluid jet and RF energy
US9220558B2 (en) 2010-10-27 2015-12-29 Boston Scientific Scimed, Inc. RF renal denervation catheter with multiple independent electrodes
US9028485B2 (en) 2010-11-15 2015-05-12 Boston Scientific Scimed, Inc. Self-expanding cooling electrode for renal nerve ablation
US9668811B2 (en) 2010-11-16 2017-06-06 Boston Scientific Scimed, Inc. Minimally invasive access for renal nerve ablation
US9089350B2 (en) 2010-11-16 2015-07-28 Boston Scientific Scimed, Inc. Renal denervation catheter with RF electrode and integral contrast dye injection arrangement
US9326751B2 (en) 2010-11-17 2016-05-03 Boston Scientific Scimed, Inc. Catheter guidance of external energy for renal denervation
US9060761B2 (en) 2010-11-18 2015-06-23 Boston Scientific Scime, Inc. Catheter-focused magnetic field induced renal nerve ablation
US9023034B2 (en) 2010-11-22 2015-05-05 Boston Scientific Scimed, Inc. Renal ablation electrode with force-activatable conduction apparatus
US9192435B2 (en) 2010-11-22 2015-11-24 Boston Scientific Scimed, Inc. Renal denervation catheter with cooled RF electrode
US20120157993A1 (en) 2010-12-15 2012-06-21 Jenson Mark L Bipolar Off-Wall Electrode Device for Renal Nerve Ablation
WO2012100095A1 (en) 2011-01-19 2012-07-26 Boston Scientific Scimed, Inc. Guide-compatible large-electrode catheter for renal nerve ablation with reduced arterial injury
KR101240133B1 (ko) 2011-01-27 2013-03-11 서울대학교산학협력단 히알루론산과 알지네이트를 포함하는 상호관입고분자망목 구조의 세포전달용 지지체의 제조방법
US8871016B2 (en) 2011-08-03 2014-10-28 The Johns Hopkins University Cellulose-based hydrogels and methods of making thereof
US9175153B2 (en) 2011-03-08 2015-11-03 The Johns Hopkins University Cellulose hydrogel compositions and contact lenses for corneal applications
US9211256B2 (en) 2011-03-08 2015-12-15 The Johns Hopkins University Wound healing compositions comprising biocompatible cellulose hydrogel membranes and methods of use thereof
EP2694150A1 (en) 2011-04-08 2014-02-12 Covidien LP Iontophoresis drug delivery system and method for denervation of the renal sympathetic nerve and iontophoretic drug delivery
CN102229732B (zh) * 2011-05-11 2013-04-03 东华大学 基于半互穿网络结构的pH刺激响应性纳米水凝胶的制备
WO2013013156A2 (en) 2011-07-20 2013-01-24 Boston Scientific Scimed, Inc. Percutaneous devices and methods to visualize, target and ablate nerves
EP2734264B1 (en) 2011-07-22 2018-11-21 Boston Scientific Scimed, Inc. Nerve modulation system with a nerve modulation element positionable in a helical guide
WO2013040559A1 (en) * 2011-09-16 2013-03-21 Wake Forest University Health Sciences Fabrication of gelatin hydrogel sheet for the transplantation of corneal endothelium
KR20140115294A (ko) 2011-10-03 2014-09-30 바이오미메디카, 인코포레이티드 순응성 재료들을 또 다른 표면으로 앵커링하기 위한 중합체성 접착제
WO2013055826A1 (en) 2011-10-10 2013-04-18 Boston Scientific Scimed, Inc. Medical devices including ablation electrodes
EP2765940B1 (en) 2011-10-11 2015-08-26 Boston Scientific Scimed, Inc. Off-wall electrode device for nerve modulation
US9420955B2 (en) 2011-10-11 2016-08-23 Boston Scientific Scimed, Inc. Intravascular temperature monitoring system and method
US9364284B2 (en) 2011-10-12 2016-06-14 Boston Scientific Scimed, Inc. Method of making an off-wall spacer cage
EP2768563B1 (en) 2011-10-18 2016-11-09 Boston Scientific Scimed, Inc. Deflectable medical devices
EP2768568B1 (en) 2011-10-18 2020-05-06 Boston Scientific Scimed, Inc. Integrated crossing balloon catheter
AU2012325987B2 (en) 2011-10-21 2017-02-02 Applied Medical Resources Corporation Simulated tissue structure for surgical training
US8951251B2 (en) 2011-11-08 2015-02-10 Boston Scientific Scimed, Inc. Ostial renal nerve ablation
US9119600B2 (en) 2011-11-15 2015-09-01 Boston Scientific Scimed, Inc. Device and methods for renal nerve modulation monitoring
EP3335673B1 (en) 2011-11-21 2025-07-30 Hyalex Orthopaedics, Inc. Systems for anchoring orthopaedic implants to bone
US9119632B2 (en) 2011-11-21 2015-09-01 Boston Scientific Scimed, Inc. Deflectable renal nerve ablation catheter
CA2859967A1 (en) 2011-12-20 2013-06-27 Applied Medical Resources Corporation Advanced surgical simulation
CN102532566B (zh) * 2011-12-21 2013-09-25 四川大学 互穿网络复合水凝胶的制备方法
US9265969B2 (en) 2011-12-21 2016-02-23 Cardiac Pacemakers, Inc. Methods for modulating cell function
AU2012358143B2 (en) 2011-12-23 2015-06-11 Boston Scientific Scimed, Inc. Expandable balloon or an electrode pad with a heat sensing device
EP2797534A1 (en) 2011-12-28 2014-11-05 Boston Scientific Scimed, Inc. Device and methods for nerve modulation using a novel ablation catheter with polymeric ablative elements
JP5939796B2 (ja) * 2011-12-28 2016-06-22 学校法人 関西大学 キチンまたはキトサンと合成高分子との複合体およびその製造方法
US9050106B2 (en) 2011-12-29 2015-06-09 Boston Scientific Scimed, Inc. Off-wall electrode device and methods for nerve modulation
US9387276B2 (en) 2012-01-05 2016-07-12 President And Fellows Of Harvard College Interpenetrating networks with covalent and Ionic Crosslinks
CN102688525B (zh) * 2012-05-07 2013-11-27 东南大学 一种生物大分子水凝胶及其制备方法
WO2013169927A1 (en) 2012-05-08 2013-11-14 Boston Scientific Scimed, Inc. Renal nerve modulation devices
CN102631711B (zh) * 2012-05-16 2014-03-26 金陵科技学院 一种水凝胶角膜接触镜药物载体
CN104540465A (zh) 2012-08-24 2015-04-22 波士顿科学西美德公司 带有含单独微孔隙区域的球囊的血管内导管
US9173696B2 (en) 2012-09-17 2015-11-03 Boston Scientific Scimed, Inc. Self-positioning electrode system and method for renal nerve modulation
WO2014047411A1 (en) 2012-09-21 2014-03-27 Boston Scientific Scimed, Inc. System for nerve modulation and innocuous thermal gradient nerve block
US10549127B2 (en) 2012-09-21 2020-02-04 Boston Scientific Scimed, Inc. Self-cooling ultrasound ablation catheter
CA2885433C (en) 2012-09-26 2023-04-04 Applied Medical Resources Corporation Surgical training model for laparoscopic procedures
JP6245531B2 (ja) 2012-09-27 2017-12-13 アプライド メディカル リソーシーズ コーポレイション 腹腔鏡下手技用の外科用訓練モデル
US10679520B2 (en) 2012-09-27 2020-06-09 Applied Medical Resources Corporation Surgical training model for laparoscopic procedures
EP2906135A2 (en) 2012-10-10 2015-08-19 Boston Scientific Scimed, Inc. Renal nerve modulation devices and methods
CN102895699A (zh) * 2012-11-19 2013-01-30 江南大学 一种用于皮肤创伤修复的复合水凝胶敷料的制备方法
EP3660816B1 (en) 2013-03-01 2021-10-13 Applied Medical Resources Corporation Advanced surgical simulation constructions and methods
WO2014143571A1 (en) 2013-03-11 2014-09-18 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
US9956033B2 (en) 2013-03-11 2018-05-01 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
CN103131054B (zh) * 2013-03-12 2015-05-13 武汉大学 一种高强度水凝胶
US9808311B2 (en) 2013-03-13 2017-11-07 Boston Scientific Scimed, Inc. Deflectable medical devices
WO2014149690A2 (en) 2013-03-15 2014-09-25 Boston Scientific Scimed, Inc. Medical devices and methods for treatment of hypertension that utilize impedance compensation
US9827039B2 (en) 2013-03-15 2017-11-28 Boston Scientific Scimed, Inc. Methods and apparatuses for remodeling tissue of or adjacent to a body passage
US10265122B2 (en) 2013-03-15 2019-04-23 Boston Scientific Scimed, Inc. Nerve ablation devices and related methods of use
US10336896B2 (en) * 2013-04-25 2019-07-02 The University Of Akron One-pot synthesis of highly mechanical and recoverable double-network hydrogels
CN103272268B (zh) * 2013-05-16 2015-04-22 华南理工大学 一种抗菌角膜修复材料及其制备方法
EP3011550B1 (en) 2013-06-18 2018-01-03 Applied Medical Resources Corporation Gallbladder model
US9943365B2 (en) 2013-06-21 2018-04-17 Boston Scientific Scimed, Inc. Renal denervation balloon catheter with ride along electrode support
WO2014205399A1 (en) 2013-06-21 2014-12-24 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation having rotatable shafts
US9707036B2 (en) 2013-06-25 2017-07-18 Boston Scientific Scimed, Inc. Devices and methods for nerve modulation using localized indifferent electrodes
AU2014284558B2 (en) 2013-07-01 2017-08-17 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation
US10413357B2 (en) 2013-07-11 2019-09-17 Boston Scientific Scimed, Inc. Medical device with stretchable electrode assemblies
US10660698B2 (en) 2013-07-11 2020-05-26 Boston Scientific Scimed, Inc. Devices and methods for nerve modulation
WO2015010074A1 (en) 2013-07-19 2015-01-22 Boston Scientific Scimed, Inc. Spiral bipolar electrode renal denervation balloon
EP3024405A1 (en) 2013-07-22 2016-06-01 Boston Scientific Scimed, Inc. Renal nerve ablation catheter having twist balloon
EP3024406B1 (en) 2013-07-22 2019-06-19 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation
US10198966B2 (en) 2013-07-24 2019-02-05 Applied Medical Resources Corporation Advanced first entry model for surgical simulation
JP6517201B2 (ja) 2013-07-24 2019-05-22 アプライド メディカル リソーシーズ コーポレイション ファーストエントリーモデル
JP6159888B2 (ja) 2013-08-22 2017-07-05 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． 腎神経変調バルーンへの接着性を向上させたフレキシブル回路
US9895194B2 (en) 2013-09-04 2018-02-20 Boston Scientific Scimed, Inc. Radio frequency (RF) balloon catheter having flushing and cooling capability
EP3043835B1 (en) * 2013-09-09 2020-08-12 UAB Ferentis Transparent hydrogel and method of making the same from functionalized natural polymers
EP3043733A1 (en) 2013-09-13 2016-07-20 Boston Scientific Scimed, Inc. Ablation balloon with vapor deposited cover layer
EP3057624B1 (en) 2013-10-14 2018-01-31 UAB Ferentis Regenerative prostheses as alternatives to donor corneas for transplantation
US11246654B2 (en) 2013-10-14 2022-02-15 Boston Scientific Scimed, Inc. Flexible renal nerve ablation devices and related methods of use and manufacture
US9687166B2 (en) 2013-10-14 2017-06-27 Boston Scientific Scimed, Inc. High resolution cardiac mapping electrode array catheter
US9770606B2 (en) 2013-10-15 2017-09-26 Boston Scientific Scimed, Inc. Ultrasound ablation catheter with cooling infusion and centering basket
WO2015057584A1 (en) 2013-10-15 2015-04-23 Boston Scientific Scimed, Inc. Medical device balloon
EP3057521B1 (en) 2013-10-18 2020-03-25 Boston Scientific Scimed, Inc. Balloon catheters with flexible conducting wires
JP2016534842A (ja) 2013-10-25 2016-11-10 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． 除神経フレックス回路における埋め込み熱電対
JP2016539226A (ja) 2013-11-20 2016-12-15 トラスティーズ オブ ボストン ユニバーシティ 注射可能な組織補充物
KR101664444B1 (ko) * 2013-12-13 2016-10-12 재단법인 유타 인하 디디에스 및 신의료기술개발 공동연구소 생분해성 의료용 접착제 또는 실란트 조성물
CN103655002A (zh) * 2013-12-13 2014-03-26 无锡合众信息科技有限公司 一种水凝胶人工晶体及其制备方法
US9512279B2 (en) * 2013-12-18 2016-12-06 Universite Cegy-Pontoise Interpenetrating polymer network
CN105899157B (zh) 2014-01-06 2019-08-09 波士顿科学国际有限公司 抗撕裂柔性电路组件
US9907609B2 (en) 2014-02-04 2018-03-06 Boston Scientific Scimed, Inc. Alternative placement of thermal sensors on bipolar electrode
US11000679B2 (en) 2014-02-04 2021-05-11 Boston Scientific Scimed, Inc. Balloon protection and rewrapping devices and related methods of use
KR102438168B1 (ko) 2014-03-26 2022-08-31 어플라이드 메디컬 리소시스 코포레이션 시뮬레이션된 절개가능 조직
KR102718882B1 (ko) 2014-11-13 2024-10-17 어플라이드 메디컬 리소시스 코포레이션 시뮬레이션된 조직 모델들 및 방법들
WO2016100355A1 (en) * 2014-12-15 2016-06-23 The Regents Of The University Of Colorado, A Body Corporate Biocompatible hydrogels, systems including the hydrogels, and methods of using and forming same
EP4620662A2 (en) 2015-02-19 2025-09-24 Applied Medical Resources Corporation Simulated tissue structures and methods
EP3253315B1 (en) 2015-05-14 2019-01-02 Applied Medical Resources Corporation Synthetic tissue structures for electrosurgical training and simulation
EP4057260A1 (en) 2015-06-09 2022-09-14 Applied Medical Resources Corporation Hysterectomy model
JP7009355B2 (ja) 2015-07-16 2022-01-25 アプライド メディカル リソーシーズ コーポレイション 模擬切開可能組織
KR102646090B1 (ko) 2015-07-22 2024-03-12 어플라이드 메디컬 리소시스 코포레이션 충수절제술 모델
US11077228B2 (en) 2015-08-10 2021-08-03 Hyalex Orthopaedics, Inc. Interpenetrating polymer networks
KR102649261B1 (ko) 2015-10-02 2024-03-20 어플라이드 메디컬 리소시스 코포레이션 자궁 절제술 모델
ES2955662T3 (es) 2015-11-20 2023-12-05 Applied Med Resources Tejido diseccionable simulado
WO2017165490A1 (en) * 2016-03-22 2017-09-28 President And Fellows Of Harvard College Biocompatible adhesives and methods of use thereof
CN105833344B (zh) * 2016-04-26 2019-04-26 青岛慧生惠众生物科技有限公司 一种可注射水凝胶在制备眼内填充物中的应用
CN106243600B (zh) * 2016-06-03 2017-10-24 深圳市前海金卓生物技术有限公司 一种用于油水分离的基质
KR102405187B1 (ko) 2016-06-27 2022-06-07 어플라이드 메디컬 리소시스 코포레이션 시뮬레이션된 복벽
CN113456889B (zh) * 2016-07-27 2022-06-28 珐博进(中国)医药技术开发有限公司 生物合成角膜
EP3291208B1 (en) * 2016-08-31 2020-09-30 Ricoh Company, Ltd. Hydrogel structure, blood vessel, internal organ model, practice tool for medical procedure, and method of manufacturing the hydrogel structure
CN110494156B (zh) 2016-10-13 2022-11-22 熹微(苏州)生物医药科技有限公司 基于胶原和胶原样肽的水凝胶、角膜植入物、填料胶及其用途
WO2018144966A1 (en) * 2017-02-06 2018-08-09 The Board Of Trustees Of The Leland Stanford Junior University Bioconjugation methods for targeted in situ therapeutic delivery
ES3004046T3 (en) 2017-02-14 2025-03-11 Applied Med Resources Laparoscopic training system
US10847057B2 (en) 2017-02-23 2020-11-24 Applied Medical Resources Corporation Synthetic tissue structures for electrosurgical training and simulation
BR112020001516A2 (pt) * 2017-07-27 2020-07-21 University Health Network polímero condutivo à base de ácido benzoico que contém biomaterial para melhoria da condução de tecidos in vitro e in vivo
CN107469139B (zh) * 2017-07-31 2021-01-22 河南工程学院 一种兼具有抗菌和消炎效果的高强度创伤敷料的制备方法
CN108144109A (zh) * 2017-12-28 2018-06-12 浙江海创医疗器械有限公司 一种含蜂蜜的互穿网络交联结构的水凝胶敷料
US12168082B2 (en) * 2017-12-29 2024-12-17 Medicrinia, Co., Ltd. Composition for regeneration of human fibrous cartilage or elastic cartilage
US11116561B2 (en) 2018-01-24 2021-09-14 Medtronic Ardian Luxembourg S.A.R.L. Devices, agents, and associated methods for selective modulation of renal nerves
CN109021166A (zh) * 2018-07-03 2018-12-18 北京理工大学 一种简易快速制备高粘附作用力水凝胶双层膜的方法
US10869950B2 (en) 2018-07-17 2020-12-22 Hyalex Orthopaedics, Inc. Ionic polymer compositions
JP2020055916A (ja) * 2018-09-28 2020-04-09 Ｓｐｉｂｅｒ株式会社 モールド成形体、モールド成形体の製造方法、およびモールド成形体の柔軟性調整方法
CN109589455B (zh) * 2018-11-07 2022-02-15 山东大学第二医院 一种热变性胶原蛋白或热变性真皮支架替代物及制备方法
CN109481730B (zh) * 2018-11-27 2021-10-26 五邑大学 海藻酸钙/聚乙二醇(二醇)二丙烯酸酯三维纤维网络凝胶及其制备方法和应用
JP7198529B2 (ja) * 2018-11-30 2023-01-04 ネクストバイオメディカル カンパニー リミテッド 生分解性高分子を含む化学塞栓用水和ゲル粒子
CN111481735A (zh) * 2019-01-25 2020-08-04 华中科技大学同济医学院附属协和医院 一种医用抗菌护创水凝胶敷料及其制备方法
EP3965837B1 (en) * 2019-05-07 2025-11-26 Roquette Freres Novel polysaccharide-based hydrogel scaffolds for wound care
KR102786565B1 (ko) * 2019-07-19 2025-03-24 주식회사 엘지화학 상호 침투형 구조 비드 및 그 제조 방법
KR102740475B1 (ko) * 2019-07-19 2024-12-06 주식회사 엘지화학 상호 침투형 구조 비드 및 그 제조 방법
CN110448727B (zh) * 2019-09-17 2021-10-19 南通大学 一种粘性水凝胶材料、免缝合人工神经导管及其制备方法
CN110760076B (zh) * 2019-11-06 2022-04-08 大连理工大学 一种基于胶体颗粒-iPRF双网络结构的可注射、高强度复合水凝胶及其制备方法和应用
CN110743038B (zh) * 2019-11-06 2021-09-10 大连理工大学 一种双网络结构复合水凝胶及其制备方法和应用
CN112108083A (zh) * 2020-09-09 2020-12-22 江南大学 一种n-烷基乳糖胺表面活性剂小分子水凝胶及其制备方法
EP4247446A4 (en) * 2020-11-18 2024-10-02 The University of British Columbia Protein hydrogels and methods for their preparation
CN113134113B (zh) * 2021-04-07 2022-07-01 赛克赛斯生物科技股份有限公司 可吸收止血流体明胶的制备方法及可吸收止血流体明胶
WO2022272107A1 (en) * 2021-06-24 2022-12-29 Rvo 2.0, Inc, D/B/A Optics Medical Corneal inlay implant
WO2022272090A1 (en) * 2021-06-24 2022-12-29 Rvo 2.0, Inc, D/B/A Optics Medical Hydrogel composition and methods of use
CN114381083B (zh) * 2021-12-17 2023-03-24 浙江理工大学上虞工业技术研究院有限公司 一种角膜接触镜用抗菌抗氧化水凝胶及其制备方法
CN114716724B (zh) * 2022-03-16 2023-08-22 华南理工大学 一种基于墨鱼骨的仿生智能水凝胶及其制备方法
CN114796620B (zh) * 2022-04-24 2023-09-29 广东顺德工业设计研究院(广东顺德创新设计研究院) 一种用作医用植入材料的互穿网络水凝胶及其制备方法和应用
CN114773692B (zh) * 2022-06-20 2022-09-27 北京智枢生物科技有限公司 一种可长期控制ngf释放的活性生物凝胶及其应用
CN116392397B (zh) * 2023-04-13 2024-05-31 四川大学 一种光响应排龈材料及制备方法和应用
JPWO2024219027A1 (enExample) * 2023-04-21 2024-10-24
CN116985489B (zh) * 2023-07-18 2025-05-30 郑州大学 一种智能响应的双层水凝胶及其制备方法和应用
CN117467074B (zh) * 2023-10-23 2024-07-12 苏州健雄职业技术学院 一种基于两性离子聚合物凝胶的生物降解纳米酶的制备与应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4388428A (en) * 1981-07-20 1983-06-14 National Patent Development Corporation Biologically stabilized compositions comprising collagen as the major component with ethylenically unsaturated compounds used as contact lenses
JPS6279054A (ja) * 1985-08-21 1987-04-11 キングストン・テクノロジ−ズ・インコ−ポレ−テツド 眼球内人工レンズ
US5716633A (en) * 1986-10-16 1998-02-10 Cbs Lens, A California General Partnership Collagen-hydrogel for promoting epithelial cell growth and regeneration of the stroma and artificial lens using the same
KR20050083626A (ko) * 2002-08-09 2005-08-26 오타와 헬쓰 리서치 인스티튜트 생체 합성 매트릭스 및 그의 용도

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4452929A (en) 1983-09-09 1984-06-05 Celanese Corporation Water reducible epoxy based coating compositions
JPS6145765A (ja) * 1984-08-07 1986-03-05 宇部興産株式会社 血管補綴物及びその製造方法
US5112350A (en) * 1986-10-16 1992-05-12 Cbs Lens, A California General Partnership Method for locating on a cornea an artificial lens fabricated from a collagen-hydrogel for promoting epithelial cell growth and regeneration of the stroma
BR9007643A (pt) * 1989-09-15 1992-08-18 Chiron Ophthalmics Inc Metodo para se conseguir a epitelizacao de lentes sinteticas
US5112250A (en) * 1991-05-31 1992-05-12 Wang Tsan Chi T-type coaxial cable connector
IT1260154B (it) * 1992-07-03 1996-03-28 Lanfranco Callegaro Acido ialuronico e suoi derivati in polimeri interpenetranti (ipn)
US5632773A (en) * 1994-05-03 1997-05-27 Allergan, Inc. Biostable corneal implants
US5518732A (en) * 1995-02-14 1996-05-21 Chiron Vision, Inc. Bio-erodible ophthalmic shield
EP1704878B1 (en) * 1995-12-18 2013-04-10 AngioDevice International GmbH Crosslinked polymer compositions and methods for their use
US5746633A (en) * 1996-01-22 1998-05-05 Jeffrey; Lawrence W. Personal flotation device
US5718012A (en) * 1996-05-28 1998-02-17 Organogenesis, Inc. Method of strength enhancement of collagen constructs
CN1176272A (zh) * 1996-09-12 1998-03-18 翟光远 蓖麻油型互穿网络聚合物的制备方法
CN1102614C (zh) * 1996-12-20 2003-03-05 香港中文大学 新型高分子凝胶体及其应用
US6030634A (en) * 1996-12-20 2000-02-29 The Chinese University Of Hong Kong Polymer gel composition and uses therefor
US6224893B1 (en) * 1997-04-11 2001-05-01 Massachusetts Institute Of Technology Semi-interpenetrating or interpenetrating polymer networks for drug delivery and tissue engineering
US6113629A (en) * 1998-05-01 2000-09-05 Micrus Corporation Hydrogel for the therapeutic treatment of aneurysms
US6899889B1 (en) * 1998-11-06 2005-05-31 Neomend, Inc. Biocompatible material composition adaptable to diverse therapeutic indications
US20030020870A1 (en) * 2001-06-27 2003-01-30 Zms, Llc Biomedical molding materials from semi-solid precursors
TW574302B (en) * 2001-08-10 2004-02-01 Ind Tech Res Inst A method for producing cross-linked hyaluronic acid-protein bio-composites
US6552172B2 (en) * 2001-08-30 2003-04-22 Habto Biotech, Inc. Fibrin nanoparticles and uses thereof
AU2003234159A1 (en) * 2002-04-22 2003-11-03 Purdue Research Foundation Hydrogels having enhanced elasticity and mechanical strength properties
JP2005532094A (ja) * 2002-06-18 2005-10-27 ザ・ボード・オブ・トラスティーズ・オブ・ザ・レランド・スタンフォード・ジュニア・ユニバーシティ 人工角膜
US7476398B1 (en) * 2002-06-28 2009-01-13 Universite Laval Corneal implant and uses thereof
US20040147016A1 (en) * 2002-09-30 2004-07-29 Rowley Jonathan A. Programmable scaffold and methods for making and using the same
US7279174B2 (en) * 2003-05-08 2007-10-09 Advanced Cardiovascular Systems, Inc. Stent coatings comprising hydrophilic additives
CA2430185A1 (en) * 2003-05-28 2004-11-28 Heather D. Sheardown Ophthalmic biomaterials and preparation thereof
WO2005113608A1 (en) * 2004-05-20 2005-12-01 Mentor Corporation Method of covalently linking hyaluronan and chitosan
KR101298442B1 (ko) * 2004-08-13 2013-08-22 내셔날 리서치 카운실 오브 캐나다 안과용 장치 및 이와 관련된 방법 및 조성물
US7857849B2 (en) * 2004-10-05 2010-12-28 The Board Of Trustees Of The Leland Stanford Junior Iniversity Artificial corneal implant
US20060287721A1 (en) * 2004-10-05 2006-12-21 David Myung Artificial cornea

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4388428A (en) * 1981-07-20 1983-06-14 National Patent Development Corporation Biologically stabilized compositions comprising collagen as the major component with ethylenically unsaturated compounds used as contact lenses
JPS6279054A (ja) * 1985-08-21 1987-04-11 キングストン・テクノロジ−ズ・インコ−ポレ−テツド 眼球内人工レンズ
US5716633A (en) * 1986-10-16 1998-02-10 Cbs Lens, A California General Partnership Collagen-hydrogel for promoting epithelial cell growth and regeneration of the stroma and artificial lens using the same
KR20050083626A (ko) * 2002-08-09 2005-08-26 오타와 헬쓰 리서치 인스티튜트 생체 합성 매트릭스 및 그의 용도

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101944008B1 (ko) * 2017-09-18 2019-01-30 (주) 제이씨바이오 히알루론산을 포함하는 투명 하이드로겔 막 및 이를 이용한 콘택트렌즈
WO2019054850A1 (ko) * 2017-09-18 2019-03-21 (주)제이씨바이오 히알루론산을 포함하는 투명 하이드로겔 막 및 이를 이용한 콘택트렌즈
US11034801B2 (en) 2017-09-18 2021-06-15 Jcbio Co., Ltd. Transparent hydrogel membrane including hyaluronic acid, and contact lens including same

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JP2009507110A (ja) 2009-02-19
EP2535041A1 (en) 2012-12-19
WO2007028258A2 (en) 2007-03-15
KR20080065973A (ko) 2008-07-15
JP5661722B2 (ja) 2015-01-28
WO2007028258A3 (en) 2007-11-08
CN101305052A (zh) 2008-11-12
AU2006289625A1 (en) 2007-03-15
CA2621824C (en) 2014-10-07
EP1934289A2 (en) 2008-06-25
JP2013039425A (ja) 2013-02-28
CN101305052B (zh) 2012-10-10
EP1934289A4 (en) 2011-07-20
SG10201807556TA (en) 2018-10-30
CA2621824A1 (en) 2007-03-15
AU2006289625B2 (en) 2013-08-29
SG165337A1 (en) 2010-10-28
HK1125395A1 (en) 2009-08-07

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