KR101377116B1 - 면역 및 자가면역의 조절제로서의 세라마이드 유도체 - Google Patents

면역 및 자가면역의 조절제로서의 세라마이드 유도체 Download PDF

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KR101377116B1
KR101377116B1 KR1020077003168A KR20077003168A KR101377116B1 KR 101377116 B1 KR101377116 B1 KR 101377116B1 KR 1020077003168 A KR1020077003168 A KR 1020077003168A KR 20077003168 A KR20077003168 A KR 20077003168A KR 101377116 B1 KR101377116 B1 KR 101377116B1
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cells
ceramide
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glycolipids
galactosyl ceramide
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KR20070023825A (ko
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스티븐 에이 포셀리
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알버트 아인슈타인 컬리지 오브 메디신 오브 예쉬바 유니버시티
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/06—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical being a hydroxyalkyl group esterified by a fatty acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants

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  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
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  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
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KR1020077003168A 2004-08-27 2005-08-26 면역 및 자가면역의 조절제로서의 세라마이드 유도체 Expired - Fee Related KR101377116B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US60536204P 2004-08-27 2004-08-27
US60/605,362 2004-08-27
PCT/US2005/030330 WO2006026389A2 (en) 2004-08-27 2005-08-26 Ceramide derivatives as modulators of immunity and autoimmunity

Related Child Applications (1)

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KR1020127025454A Division KR20120116511A (ko) 2004-08-27 2005-08-26 면역 및 자가면역의 조절제로서의 세라마이드 유도체

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KR20070023825A KR20070023825A (ko) 2007-02-28
KR101377116B1 true KR101377116B1 (ko) 2014-03-24

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KR1020077003168A Expired - Fee Related KR101377116B1 (ko) 2004-08-27 2005-08-26 면역 및 자가면역의 조절제로서의 세라마이드 유도체
KR1020127025454A Ceased KR20120116511A (ko) 2004-08-27 2005-08-26 면역 및 자가면역의 조절제로서의 세라마이드 유도체

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Country Status (10)

Country Link
US (1) US7772380B2 (https=)
EP (1) EP1784196B1 (https=)
JP (3) JP5226311B2 (https=)
KR (2) KR101377116B1 (https=)
CN (1) CN101010086B (https=)
AU (1) AU2005280163B2 (https=)
CA (1) CA2577009C (https=)
IL (1) IL181054A (https=)
NZ (1) NZ553320A (https=)
WO (1) WO2006026389A2 (https=)

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JP7714237B2 (ja) * 2020-11-12 2025-07-29 国立研究開発法人理化学研究所 擬似糖脂質誘導体並びにその合成中間体、製造方法及び用途
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Citations (1)

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CN101010086B (zh) 2013-05-29
NZ553320A (en) 2011-02-25
IL181054A0 (en) 2007-07-04
CA2577009C (en) 2017-05-02
CN101010086A (zh) 2007-08-01
CA2577009A1 (en) 2006-03-09
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IL181054A (en) 2013-10-31
AU2005280163A1 (en) 2006-03-09
EP1784196A4 (en) 2012-05-30
US20060052316A1 (en) 2006-03-09
AU2005280163B2 (en) 2011-11-24
KR20120116511A (ko) 2012-10-22
JP2012211182A (ja) 2012-11-01
KR20070023825A (ko) 2007-02-28
US7772380B2 (en) 2010-08-10
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