KR101368525B1 - 저혈당 증상을 저하시키기 위한 ｄｐｐ-ⅳ 억제제의 용도 - Google Patents

저혈당 증상을 저하시키기 위한 ｄｐｐ-ⅳ 억제제의 용도 Download PDF

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Publication number
KR101368525B1
KR101368525B1 KR1020087006646A KR20087006646A KR101368525B1 KR 101368525 B1 KR101368525 B1 KR 101368525B1 KR 1020087006646 A KR1020087006646 A KR 1020087006646A KR 20087006646 A KR20087006646 A KR 20087006646A KR 101368525 B1 KR101368525 B1 KR 101368525B1
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South Korea
Prior art keywords
insulin
patient
daily
pharmaceutical composition
dpp
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Expired - Fee Related
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English (en)
Korean (ko)
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KR20080046198A (ko
Inventor
뵈르크 발칸
다피트 그렌필레 홀메스
토마스 에드워드 휴즈
에드윈 베르나르드 빌하우어
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노파르티스 아게
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020087006646A 2005-09-20 2006-09-18 저혈당 증상을 저하시키기 위한 ｄｐｐ-ⅳ 억제제의 용도 Expired - Fee Related KR101368525B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US71885605P 2005-09-20 2005-09-20
US60/718,856 2005-09-20
US78675506P 2006-03-28 2006-03-28
US60/786,755 2006-03-28
PCT/US2006/036338 WO2007035665A1 (en) 2005-09-20 2006-09-18 Use of a dpp-iv inhibitor to reduce hypoglycemic events

Publications (2)

Publication Number Publication Date
KR20080046198A KR20080046198A (ko) 2008-05-26
KR101368525B1 true KR101368525B1 (ko) 2014-03-06

Family

ID=37533536

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020087006646A Expired - Fee Related KR101368525B1 (ko) 2005-09-20 2006-09-18 저혈당 증상을 저하시키기 위한 ｄｐｐ-ⅳ 억제제의 용도

Country Status (12)

Country Link
US (2) US8143217B2 (https=)
EP (1) EP1928499B1 (https=)
JP (1) JP5072848B2 (https=)
KR (1) KR101368525B1 (https=)
AT (1) ATE514435T1 (https=)
AU (1) AU2006292377B2 (https=)
BR (1) BRPI0616195A2 (https=)
CA (1) CA2622579C (https=)
PL (1) PL1928499T3 (https=)
PT (1) PT1928499E (https=)
RU (1) RU2440143C2 (https=)
WO (1) WO2007035665A1 (https=)

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TW202313579A (zh) 2021-06-03 2023-04-01 瑞典商艾爾比瑞歐公司 苯并噻(二)氮呯(benzothia(di)azepine)化合物及其作為膽酸調節劑之用途
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JP5072848B2 (ja) 2012-11-14
US20120149639A1 (en) 2012-06-14
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PT1928499E (pt) 2011-09-09
JP2009508955A (ja) 2009-03-05
AU2006292377B2 (en) 2011-03-03
AU2006292377A1 (en) 2007-03-29
US20080300171A1 (en) 2008-12-04
CA2622579A1 (en) 2007-03-29
EP1928499A1 (en) 2008-06-11
CA2622579C (en) 2013-12-31
KR20080046198A (ko) 2008-05-26
ATE514435T1 (de) 2011-07-15
PL1928499T3 (pl) 2011-11-30
EP1928499B1 (en) 2011-06-29
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