KR101368525B1 - 저혈당 증상을 저하시키기 위한 ｄｐｐ-ⅳ 억제제의 용도 - Google Patents

저혈당 증상을 저하시키기 위한 ｄｐｐ-ⅳ 억제제의 용도 Download PDF

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Publication number
KR101368525B1
KR101368525B1 KR1020087006646A KR20087006646A KR101368525B1 KR 101368525 B1 KR101368525 B1 KR 101368525B1 KR 1020087006646 A KR1020087006646 A KR 1020087006646A KR 20087006646 A KR20087006646 A KR 20087006646A KR 101368525 B1 KR101368525 B1 KR 101368525B1
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Prior art keywords
insulin
patient
daily
pharmaceutical composition
dpp
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Expired - Fee Related
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Korean (ko)
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KR20080046198A (ko
Inventor
뵈르크 발칸
다피트 그렌필레 홀메스
토마스 에드워드 휴즈
에드윈 베르나르드 빌하우어
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노파르티스 아게
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020087006646A 2005-09-20 2006-09-18 저혈당 증상을 저하시키기 위한 ｄｐｐ-ⅳ 억제제의 용도 Expired - Fee Related KR101368525B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US71885605P 2005-09-20 2005-09-20
US60/718,856 2005-09-20
US78675506P 2006-03-28 2006-03-28
US60/786,755 2006-03-28
PCT/US2006/036338 WO2007035665A1 (en) 2005-09-20 2006-09-18 Use of a dpp-iv inhibitor to reduce hypoglycemic events

Publications (2)

Publication Number Publication Date
KR20080046198A KR20080046198A (ko) 2008-05-26
KR101368525B1 true KR101368525B1 (ko) 2014-03-06

Family

ID=37533536

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020087006646A Expired - Fee Related KR101368525B1 (ko) 2005-09-20 2006-09-18 저혈당 증상을 저하시키기 위한 ｄｐｐ-ⅳ 억제제의 용도

Country Status (12)

Country Link
US (2) US8143217B2 (enExample)
EP (1) EP1928499B1 (enExample)
JP (1) JP5072848B2 (enExample)
KR (1) KR101368525B1 (enExample)
AT (1) ATE514435T1 (enExample)
AU (1) AU2006292377B2 (enExample)
BR (1) BRPI0616195A2 (enExample)
CA (1) CA2622579C (enExample)
PL (1) PL1928499T3 (enExample)
PT (1) PT1928499E (enExample)
RU (1) RU2440143C2 (enExample)
WO (1) WO2007035665A1 (enExample)

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AU2006292377A1 (en) 2007-03-29
EP1928499B1 (en) 2011-06-29
BRPI0616195A2 (pt) 2011-06-14
JP2009508955A (ja) 2009-03-05
RU2008115114A (ru) 2009-11-27
AU2006292377B2 (en) 2011-03-03
PL1928499T3 (pl) 2011-11-30
EP1928499A1 (en) 2008-06-11
WO2007035665A1 (en) 2007-03-29
PT1928499E (pt) 2011-09-09
CA2622579A1 (en) 2007-03-29
RU2440143C2 (ru) 2012-01-20
ATE514435T1 (de) 2011-07-15
CA2622579C (en) 2013-12-31
JP5072848B2 (ja) 2012-11-14
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