KR101245065B1 - 이민의 수소화 - Google Patents

이민의 수소화 Download PDF

Info

Publication number
KR101245065B1
KR101245065B1 KR1020107019544A KR20107019544A KR101245065B1 KR 101245065 B1 KR101245065 B1 KR 101245065B1 KR 1020107019544 A KR1020107019544 A KR 1020107019544A KR 20107019544 A KR20107019544 A KR 20107019544A KR 101245065 B1 KR101245065 B1 KR 101245065B1
Authority
KR
South Korea
Prior art keywords
formula
imine
diphenylphosphino
hydrogen
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1020107019544A
Other languages
English (en)
Korean (ko)
Other versions
KR20100133370A (ko
Inventor
자이데브 라즈니칸트 쉬로프
비크램 라즈니칸트 쉬로프
비르자 샨커
Original Assignee
유나이티드 포스포러스 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 유나이티드 포스포러스 리미티드 filed Critical 유나이티드 포스포러스 리미티드
Publication of KR20100133370A publication Critical patent/KR20100133370A/ko
Application granted granted Critical
Publication of KR101245065B1 publication Critical patent/KR101245065B1/ko
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/17Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/18Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
KR1020107019544A 2008-04-17 2009-04-16 이민의 수소화 Expired - Fee Related KR101245065B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN877/MUM/2008 2008-04-17
IN877MU2008 2008-04-17
PCT/IN2009/000237 WO2009136409A2 (en) 2008-04-17 2009-04-16 Hydrogenation of imines

Publications (2)

Publication Number Publication Date
KR20100133370A KR20100133370A (ko) 2010-12-21
KR101245065B1 true KR101245065B1 (ko) 2013-03-18

Family

ID=41265115

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020107019544A Expired - Fee Related KR101245065B1 (ko) 2008-04-17 2009-04-16 이민의 수소화

Country Status (10)

Country Link
US (1) US8461386B2 (enExample)
EP (1) EP2265373A4 (enExample)
JP (1) JP2011518150A (enExample)
KR (1) KR101245065B1 (enExample)
CN (1) CN102006930B (enExample)
AU (1) AU2009245307B2 (enExample)
BR (1) BRPI0907343A8 (enExample)
RU (1) RU2476422C2 (enExample)
UA (1) UA100732C2 (enExample)
WO (1) WO2009136409A2 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103189341B (zh) * 2010-11-02 2015-06-17 Upl有限公司 用于制备羟基膦配位体的手性中间体
EP2892877B1 (en) * 2012-09-06 2017-06-21 Council of Scientific and Industrial Research Process for the preparation of (s)-2-ethyl-n-(1-methoxypropan -2-yl)-6-methyl aniline
WO2014164801A1 (en) * 2013-03-11 2014-10-09 Rutgers, The State University Of New Jersey Metallorganocatalysis for asymmetric transformations
CN104445068B (zh) * 2014-11-21 2016-09-28 山东侨昌化学有限公司 一种异丙甲草胺生产过程中副产氢气的回收方法
CN108218726B (zh) * 2016-12-14 2020-08-18 浙江省化工研究院有限公司 一种制备(s)-mea胺醚的方法
CN110551034B (zh) * 2018-05-31 2021-11-09 中国科学院大连化学物理研究所 一种酮的不对称还原胺化方法
CN110551037B (zh) * 2018-05-31 2021-11-09 中国科学院大连化学物理研究所 一种铱/手性双膦体系催化亚胺不对称氢化方法
CN109096137A (zh) * 2018-07-30 2018-12-28 山东万豪肥业有限公司 一种精异丙甲草胺的合成方法
EP4003957B1 (en) * 2019-07-25 2024-04-17 Medichem, S.A. Process for the synthesis of n-alkyl-4-pyridinamines
GB202216812D0 (en) * 2022-11-10 2022-12-28 Univ Court Univ St Andrews Process
CN120699067B (zh) * 2025-08-18 2025-11-21 瑞博(苏州)制药有限公司 新型手性二茂铁桥联联萘骨架膦配体及其应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6166257A (en) 1996-06-28 2000-12-26 Rhodia Chimie Asymmetric hydrogenation method of a ketonic compound and derivative
US20070213540A1 (en) 2006-03-09 2007-09-13 Degussa Ag Process for the hydrogenation of imines

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD112988A5 (enExample) * 1972-06-06 1975-05-12
EP0256982B1 (de) * 1986-08-04 1991-08-28 Ciba-Geigy Ag Verfahren zur Herstellung von optisch aktiven sekundären Arylaminen
MY109091A (en) * 1992-12-29 1996-11-30 Syngenta Participations Ag Process for the preparation of 2-alkyl-6-methyl-n-(1''''''''- methoxy-2''''''''-propyl)-aniline and a process for the preparation of their chloracetanilides.
ES2123953T3 (es) * 1994-02-02 1999-01-16 Novartis Ag Proceso para la hidrogenacion de iminas.
EP1206427B1 (en) * 1999-08-23 2005-11-09 The Penn State Research Foundation Chiral ligands, transition-metal complexes thereof and uses thereof in asymmetric reactions
DE10223593A1 (de) * 2002-05-27 2003-12-11 Degussa Hydroxydiphosphine und deren Verwendung in der Katalyse
EP1595888A1 (en) * 2004-05-11 2005-11-16 Degussa AG Cycloolefin phosphine ligands and their use in catalysis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6166257A (en) 1996-06-28 2000-12-26 Rhodia Chimie Asymmetric hydrogenation method of a ketonic compound and derivative
US20070213540A1 (en) 2006-03-09 2007-09-13 Degussa Ag Process for the hydrogenation of imines

Also Published As

Publication number Publication date
KR20100133370A (ko) 2010-12-21
US20110054217A1 (en) 2011-03-03
AU2009245307B2 (en) 2014-01-30
EP2265373A4 (en) 2014-04-23
BRPI0907343A2 (pt) 2015-07-28
WO2009136409A3 (en) 2009-12-30
RU2476422C2 (ru) 2013-02-27
RU2010145490A (ru) 2012-05-27
JP2011518150A (ja) 2011-06-23
BRPI0907343A8 (pt) 2017-05-23
EP2265373A2 (en) 2010-12-29
CN102006930B (zh) 2013-09-25
US8461386B2 (en) 2013-06-11
UA100732C2 (ru) 2013-01-25
WO2009136409A2 (en) 2009-11-12
AU2009245307A1 (en) 2009-11-12
CN102006930A (zh) 2011-04-06

Similar Documents

Publication Publication Date Title
KR20100133370A (ko) 이민의 수소화
US6037500A (en) Asymmetric synthesis catalyzed by transition metal complexes with cyclic chiral phosphine ligands
Hoen et al. Enantioselective synthesis of β 2-amino acids using rhodium-catalyzed hydrogenation
US6451727B2 (en) Catalysts for use in asymmetric synthesis comprising transition metals and chiral amine oxazolinyl ligands
CN102050688A (zh) 一种酮衍生的n-烷基亚胺的不对称催化氢化方法
US7153809B2 (en) P-chiral phospholanes and phosphocyclic compounds and their use in asymmetric catalytic reactions
Sen et al. C 1-Symmetric diphosphorus ligands in metal-catalyzed asymmetric hydrogenation to prepare chiral compounds
WO2008077560A1 (en) Process for the preparation of optically active 2-amino-1-phenylethanols
Balogh et al. Synthesis of new N-substituted chiral phosphine–phosphoramidite ligands and their application in asymmetric hydrogenations and allylic alkylations
US8791300B2 (en) Process for preparing a substituted dimethyl-(3-arylbutyl)amine compound by homogeneous catalysis
US6583312B2 (en) Process for preparing optically active trimethyllactic acid and its esters
WO2015178846A1 (en) Process for the preparation of chiral amines from prochiral ketones
US20220119329A1 (en) Manganese Catalysts and Their Use in Hydrogenation of Ketones
US7601667B2 (en) Sulfonate catalyst and method of producing alcohol compound using the same
IL193064A (en) Metal complexes
Lorraine et al. Biaryl diphosphine ligands and their ruthenium complexes: Preparation and use for catalytic hydrogenation of ketones
US8759541B2 (en) Chiral acyclic diaminocarbene ligands, precursors therefore and their use in organic synthesis reactions
JP2002030009A (ja) l−メントールの製造方法
US9340519B2 (en) Paracyclophane-based ligands, their preparation and use in catalysis
ES2439595B1 (es) Procedimiento para la adición enantioselectiva de compuestos organozíncicos a compuestos derivados de acetofenonas
JP5001263B2 (ja) ジフェニルアラニン誘導体作製のための不斉水素化
JPWO2002062809A1 (ja) ルテニウム錯体及びアルコール化合物の製造方法
WO2015178847A1 (en) Process for the preparation of chiral amines by asymmetric hydrogenation of prochiral oximes
KR100425526B1 (ko) 키랄 디포스핀 화합물 및 이를 이용한 비대칭 반응
Kanbayashi Studies on Novel Asymmetric Allylic Substitution

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

A201 Request for examination
E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U12-oth-PR1002

Fee payment year number: 1

PG1601 Publication of registration

St.27 status event code: A-4-4-Q10-Q13-nap-PG1601

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000

LAPS Lapse due to unpaid annual fee
PC1903 Unpaid annual fee

St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 20160313

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

PC1903 Unpaid annual fee

St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 20160313

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000