KR101066192B1 - 자외선 차폐성 첩부제 - Google Patents
자외선 차폐성 첩부제 Download PDFInfo
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- KR101066192B1 KR101066192B1 KR1020057020793A KR20057020793A KR101066192B1 KR 101066192 B1 KR101066192 B1 KR 101066192B1 KR 1020057020793 A KR1020057020793 A KR 1020057020793A KR 20057020793 A KR20057020793 A KR 20057020793A KR 101066192 B1 KR101066192 B1 KR 101066192B1
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- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 235000021313 oleic acid Nutrition 0.000 description 1
- 229940055577 oleyl alcohol Drugs 0.000 description 1
- XMLQWXUVTXCDDL-UHFFFAOYSA-N oleyl alcohol Natural products CCCCCCC=CCCCCCCCCCCO XMLQWXUVTXCDDL-UHFFFAOYSA-N 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- TWNQGVIAIRXVLR-UHFFFAOYSA-N oxo(oxoalumanyloxy)alumane Chemical compound O=[Al]O[Al]=O TWNQGVIAIRXVLR-UHFFFAOYSA-N 0.000 description 1
- DXGLGDHPHMLXJC-UHFFFAOYSA-N oxybenzone Chemical compound OC1=CC(OC)=CC=C1C(=O)C1=CC=CC=C1 DXGLGDHPHMLXJC-UHFFFAOYSA-N 0.000 description 1
- 239000000312 peanut oil Substances 0.000 description 1
- 229940116257 pepper extract Drugs 0.000 description 1
- 235000019477 peppermint oil Nutrition 0.000 description 1
- 239000003208 petroleum Substances 0.000 description 1
- 239000003209 petroleum derivative Substances 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 238000001782 photodegradation Methods 0.000 description 1
- 229920006267 polyester film Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920000139 polyethylene terephthalate Polymers 0.000 description 1
- 239000005020 polyethylene terephthalate Substances 0.000 description 1
- 229920001195 polyisoprene Polymers 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 150000003097 polyterpenes Chemical class 0.000 description 1
- 235000010388 propyl gallate Nutrition 0.000 description 1
- 239000000473 propyl gallate Substances 0.000 description 1
- 229940075579 propyl gallate Drugs 0.000 description 1
- 230000001953 sensory effect Effects 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- MSFGZHUJTJBYFA-UHFFFAOYSA-M sodium dichloroisocyanurate Chemical compound [Na+].ClN1C(=O)[N-]C(=O)N(Cl)C1=O MSFGZHUJTJBYFA-UHFFFAOYSA-M 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 238000013112 stability test Methods 0.000 description 1
- 210000000434 stratum corneum Anatomy 0.000 description 1
- 229920006132 styrene block copolymer Polymers 0.000 description 1
- 229920003048 styrene butadiene rubber Polymers 0.000 description 1
- 229920000468 styrene butadiene styrene block copolymer Polymers 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 229960004492 suprofen Drugs 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000005061 synthetic rubber Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 239000004408 titanium dioxide Substances 0.000 description 1
- 235000010384 tocopherol Nutrition 0.000 description 1
- 229930003799 tocopherol Natural products 0.000 description 1
- 229960001295 tocopherol Drugs 0.000 description 1
- 239000011732 tocopherol Substances 0.000 description 1
- 239000003860 topical agent Substances 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7007—Drug-containing films, membranes or sheets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7076—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Botany (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
테이프 제제 | 시험후의 약물함량 [%] |
자외선 투과율 [%] |
외관변화 | 응집량 감소 (고착성) |
|
실시예1 | 처방1 | 90.8 | 1.92 | 없음 | 없음 |
실시예2 | 처방2 | 98.7 | 1.38 | 없음 | 없음 |
실시예3 | 처방3 | 99.9 | 0.67 | 없음 | 없음 |
실시예4 | 처방4 | 98.8 | 0.84 | 없음 | 없음 |
실시예5 | 처방5 | 100.0 | 0.44 | 없음 | 없음 |
실시예6 | 처방6 | 99.3 | 0.84 | 없음 | 없음 |
실시예7 | 처방7 | 99.5 | 0.67 | 없음 | 없음 |
비교예1 | 처방8 | 53.0 | 24.8 | 황색 | 있음 |
비교예2 | 처방9 | 77.5 | 2.83 | 엷은황색 | 일부 있음 |
비교예3 | 처방8 | 49.8 | 24.8 | 황색 | 있음 |
중량(目付) (g/m2) |
자외선투과율 (%) |
사용성 | |||
부착성 | 첩부시의 위화감 | 종합판정 | |||
테이프 제제 | 112.5 | 0.44 | ◎ | ○ | ○ |
Claims (9)
- 제 1 항에 있어서, R1 및 R2는, 동일 또는 상이하여도 좋고, C1~C4인 알킬이며, X는 Cl인 첩부제.
- 제 1 항에 있어서, 지지체가, 추가로 산화 티탄을 함유하는 것을 특징으로 하는 첩부제.
- 제 1 항 또는 제 2 항에 있어서, 지지체의 자외선 투과율이, 2% 이하인 것을 특징으로 하는 첩부제.
- 제 1 항에 있어서, 지지체의 중량이, 100g/m2 ~ 130g/m2 인 것을 특징으로 하는 첩부제.
- 제 1 항에 있어서, 비(非)스테로이드계 항염증약(NSAID)이, 케토프로펜(ketoprofen)인 것을 특징으로 하는 첩부제.
- 제 1 항에 있어서, 점착제층이, 스티렌-이소프렌-스티렌 블록 공중합체 및/또는 폴리이소부티렌으로 이루어진 것을 특징으로 하는 첩부제.
- 제 1 항에 있어서, 점착체층이, 자외선 흡수제를 함유하지 않는 것을 특징으로 하는 첩부제.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2003128934 | 2003-05-07 | ||
JPJP-P-2003-00128934 | 2003-05-07 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR20060007420A KR20060007420A (ko) | 2006-01-24 |
KR101066192B1 true KR101066192B1 (ko) | 2011-09-21 |
Family
ID=33432062
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020057020793A KR101066192B1 (ko) | 2003-05-07 | 2004-05-07 | 자외선 차폐성 첩부제 |
Country Status (14)
Country | Link |
---|---|
US (1) | US20060198880A1 (ko) |
EP (1) | EP1621188B1 (ko) |
JP (1) | JP4927403B2 (ko) |
KR (1) | KR101066192B1 (ko) |
CN (1) | CN100366240C (ko) |
AU (1) | AU2004236606B2 (ko) |
BR (1) | BRPI0410093B8 (ko) |
CA (1) | CA2524891C (ko) |
ES (1) | ES2426168T3 (ko) |
HK (1) | HK1087634A1 (ko) |
PL (1) | PL1621188T3 (ko) |
PT (1) | PT1621188E (ko) |
TW (1) | TWI327074B (ko) |
WO (1) | WO2004098575A1 (ko) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080317689A1 (en) * | 2005-02-25 | 2008-12-25 | Hisamitsu Pharmaceutical Co., Inc. | Transdermal Preparation for External Use Containing Antiinflammatory/Analgesic Agent |
US20060263420A1 (en) * | 2005-03-10 | 2006-11-23 | Hisamitsu Pharmaceutical Co., Inc. | Adhesive and plaster |
JP4974535B2 (ja) * | 2006-02-02 | 2012-07-11 | 久光製薬株式会社 | 外用製剤及びその製造方法 |
RU2441649C2 (ru) | 2006-08-04 | 2012-02-10 | Хисамицу Фармасьютикал Ко., Инк. | Адгезивный препарат |
JP4755284B2 (ja) * | 2007-09-28 | 2011-08-24 | ニチバン株式会社 | 貼付材 |
MX2010008456A (es) | 2008-01-31 | 2010-08-30 | Hisamitsu Pharmaceutical Co | Parche adhesivo. |
JP6533639B2 (ja) * | 2012-03-16 | 2019-06-19 | 株式会社コーセー | 皮膚外用剤及び紫外線によるカロテノイド含有油性成分の分解抑制方法 |
TWI630930B (zh) | 2014-02-27 | 2018-08-01 | 久光製藥股份有限公司 | 含有酮洛芬的貼劑 |
US20220257915A1 (en) * | 2021-02-17 | 2022-08-18 | Katy Hamilton | Skin Protection Device |
Citations (1)
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KR20020081460A (ko) * | 2000-03-17 | 2002-10-26 | 히사미쓰 세이야꾸 가부시키가이샤 | 자외선 차폐성의 첩부제 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60155111A (ja) * | 1983-10-20 | 1985-08-15 | Hisamitsu Pharmaceut Co Inc | 安定なケトプロフェン含有外用経皮製剤 |
WO1994026309A1 (en) * | 1993-05-19 | 1994-11-24 | Hisamitsu Pharmaceutical Co., Inc. | Solubilizing agent and external preparation containing the same |
JPH0853354A (ja) * | 1994-08-11 | 1996-02-27 | Hisamitsu Pharmaceut Co Inc | 皮膚疾患用水性貼付剤 |
WO1996011022A1 (fr) * | 1994-10-05 | 1996-04-18 | Hisamitsu Pharmaceutical Co., Inc. | Constituants de composition medicamenteuse comprenant des derives de o-toluidine n-substituee et preparation absorbable par voie cutanee |
JPH08133964A (ja) * | 1994-11-05 | 1996-05-28 | Nichiban Co Ltd | 有害紫外線吸収性粘着シート |
CN1126540C (zh) * | 1996-12-06 | 2003-11-05 | 久光制药株式会社 | 含有联苯乙酸的贴剂 |
JP3682465B2 (ja) * | 1999-03-31 | 2005-08-10 | 独立行政法人産業技術総合研究所 | 樹脂成形物表面層の改質方法およびそのための装置および表面層が改質された樹脂成形物、および樹脂成形物表面層の着色方法およびそのための装置および表面層が着色された樹脂成形物、および表面層の改質により機能性を付与された樹脂成形物 |
ES2356704T3 (es) * | 1999-07-15 | 2011-04-12 | Hisamitsu Pharmaceutical Co. Inc. | Preparaciones percutaneamente absobibles. |
JP4584381B2 (ja) * | 1999-07-30 | 2010-11-17 | 久光製薬株式会社 | フェルビナク含有貼付剤 |
AU780058B2 (en) * | 1999-12-15 | 2005-02-24 | Hisamitsu Pharmaceutical Co., Inc. | Adhesive preparations |
CN1200696C (zh) * | 2000-04-18 | 2005-05-11 | 久光制药株式会社 | 含有抗炎药的贴剂 |
JP4192411B2 (ja) * | 2000-07-12 | 2008-12-10 | コニカミノルタホールディングス株式会社 | 偏光板用保護フィルム |
US6624410B1 (en) * | 2002-02-25 | 2003-09-23 | Monitor Instruments Company, Llc | Cycloidal mass spectrometer |
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- 2004-05-07 KR KR1020057020793A patent/KR101066192B1/ko active IP Right Grant
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KR20020081460A (ko) * | 2000-03-17 | 2002-10-26 | 히사미쓰 세이야꾸 가부시키가이샤 | 자외선 차폐성의 첩부제 |
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CA2524891C (en) | 2014-07-08 |
ES2426168T3 (es) | 2013-10-21 |
BRPI0410093A (pt) | 2006-05-16 |
EP1621188A1 (en) | 2006-02-01 |
CA2524891A1 (en) | 2004-11-18 |
CN100366240C (zh) | 2008-02-06 |
CN1784219A (zh) | 2006-06-07 |
JP4927403B2 (ja) | 2012-05-09 |
WO2004098575A1 (ja) | 2004-11-18 |
TWI327074B (en) | 2010-07-11 |
BRPI0410093B1 (pt) | 2018-02-14 |
PT1621188E (pt) | 2013-09-26 |
AU2004236606A1 (en) | 2004-11-18 |
KR20060007420A (ko) | 2006-01-24 |
EP1621188A4 (en) | 2012-01-25 |
AU2004236606B2 (en) | 2010-03-11 |
PL1621188T3 (pl) | 2013-12-31 |
BRPI0410093B8 (pt) | 2021-07-27 |
HK1087634A1 (en) | 2006-10-20 |
US20060198880A1 (en) | 2006-09-07 |
TW200510007A (en) | 2005-03-16 |
JPWO2004098575A1 (ja) | 2006-07-13 |
EP1621188B1 (en) | 2013-07-10 |
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