KR101012904B1 - 안지오포이에틴-유사 단백질 3 ａｎｇｐｔｌ3을 함유하는조성물 및 이를 사용하는 방법 - Google Patents

안지오포이에틴-유사 단백질 3 ａｎｇｐｔｌ3을 함유하는조성물 및 이를 사용하는 방법 Download PDF

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KR101012904B1
KR101012904B1 KR1020047007410A KR20047007410A KR101012904B1 KR 101012904 B1 KR101012904 B1 KR 101012904B1 KR 1020047007410 A KR1020047007410 A KR 1020047007410A KR 20047007410 A KR20047007410 A KR 20047007410A KR 101012904 B1 KR101012904 B1 KR 101012904B1
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angptl3
liver
antibody
seq
lys
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나폴레옹 페라라
한스-페터 게르버
조 코발스키
마리아 테레사 피사바로
대널 에릭 셔만
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제넨테크, 인크.
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/515—Angiogenesic factors; Angiogenin
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KR1020047007410A 2001-11-16 2002-11-13 안지오포이에틴-유사 단백질 3 ａｎｇｐｔｌ3을 함유하는조성물 및 이를 사용하는 방법 Expired - Fee Related KR101012904B1 (ko)

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US33242901P 2001-11-16 2001-11-16
US60/332,429 2001-11-16

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KR1020107004734A Division KR20100029861A (ko) 2001-11-16 2002-11-13 안지오포이에틴-유사 단백질 3 ａｎｇｐｔｌ3을 함유하는 조성물 및 이를 사용하는 방법

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KR20050044485A KR20050044485A (ko) 2005-05-12
KR101012904B1 true KR101012904B1 (ko) 2011-02-08

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KR1020047007410A Expired - Fee Related KR101012904B1 (ko) 2001-11-16 2002-11-13 안지오포이에틴-유사 단백질 3 ａｎｇｐｔｌ3을 함유하는조성물 및 이를 사용하는 방법
KR1020107004734A Ceased KR20100029861A (ko) 2001-11-16 2002-11-13 안지오포이에틴-유사 단백질 3 ａｎｇｐｔｌ3을 함유하는 조성물 및 이를 사용하는 방법

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US (3) US7267819B2 (enExample)
EP (1) EP1451578B1 (enExample)
JP (2) JP5105696B2 (enExample)
KR (2) KR101012904B1 (enExample)
CN (2) CN1615440A (enExample)
AU (1) AU2002348286B2 (enExample)
CA (1) CA2464542C (enExample)
ES (1) ES2429034T3 (enExample)
IL (2) IL161542A0 (enExample)
MX (1) MXPA04004609A (enExample)
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JP5349752B2 (ja) * 2003-08-21 2013-11-20 デュシェネ インク 微量栄養素サプリメント
AU2005269716B2 (en) * 2004-07-20 2011-01-27 Genentech, Inc. Inhibitors of angiopoietin-like 4 protein, combinations, and their use
MX2007000783A (es) 2004-07-20 2007-04-09 Genentech Inc Inhibidores de proteina angiopoietina tipo 4, combinaciones y su uso.
US8604185B2 (en) 2004-07-20 2013-12-10 Genentech, Inc. Inhibitors of angiopoietin-like 4 protein, combinations, and their use
US7807645B2 (en) 2005-09-23 2010-10-05 The Regents Of The University Of California Method of treating degenerative disorders of the nervous system by administration of fibrinogen fragment
CA2672049C (en) 2006-12-08 2016-05-10 Lexicon Pharmaceuticals, Inc. Monoclonal antibodies against angptl3
US8354111B2 (en) 2008-04-14 2013-01-15 Hadasit Medical Research Services And Development Ltd. Stable cell binding chimeric peptides
CN101852805B (zh) * 2009-03-31 2015-04-01 浙江大学 Angptl3作为卵巢癌的诊断标记物的用途
PE20160507A1 (es) * 2009-07-14 2016-05-20 Scripps Research Inst Diferenciacion de celulas madre mesenquimales
AU2015200969A1 (en) * 2010-01-08 2015-03-19 Ionis Pharmaceuticals, Inc. Modulation of angiopoietin-like 3 expression
CN106146591B (zh) 2010-01-08 2020-07-31 Ionis制药公司 血管生成素样3表达的调节
JP5838474B2 (ja) * 2010-02-02 2016-01-06 アリゾナ ボード オブ リージェンツ オン ビハーフ オブ アリゾナ ステート ユニバーシティ ポリマーの配列を決定するための制御されたトンネルギャップデバイス
US20130330752A1 (en) * 2011-01-29 2013-12-12 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
AR087329A1 (es) * 2011-06-17 2014-03-19 Regeneron Pharma Anticuerpos humanos contra proteina 3 de tipo angiopoietina humana
CA2862485C (en) * 2012-01-24 2021-05-11 Inter-K Pty Limited Peptide agents for cancer therapy
UY35368A (es) * 2013-03-08 2014-10-31 Irm Llc Péptidos y composiciones para el tratamiento de daño articular
US9301971B2 (en) 2013-03-08 2016-04-05 Novartis Ag Peptides and compositions for treatment of joint damage
CN104062432B (zh) * 2013-03-22 2016-01-20 中山大学 ang2在制备ECTC血管类型肝癌诊断试剂及治疗药物中的应用
KR102482890B1 (ko) 2013-05-01 2022-12-30 아이오니스 파마수티컬즈, 인코포레이티드 아포지질단백질 (a) 발현을 조절하는 조성물 및 방법
MX383753B (es) 2013-12-24 2025-03-14 Ionis Pharmaceuticals Inc Modulación de la expresión similar a la angiopoyetina tipo 3.
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CN105021827B (zh) * 2015-07-17 2016-09-28 北京大学第一医院 检测血清血管生成素样蛋白2含量的物质在制备检测肝脏炎症和纤维化程度产品中的应用
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US10582702B2 (en) * 2016-02-04 2020-03-10 Regeneron Pharmaceuticals, Inc. Non-human animals having an engineered ANGPTL8 gene
MA43734A (fr) 2016-03-03 2018-11-28 Regeneron Pharma Procédés de traitement de patients atteints d'hyperlipidémie par administration d'un inhibiteur de pcsk9 en combinaison avec un inhibiteur d'angptl3
KR102737464B1 (ko) 2017-09-14 2024-12-02 애로우헤드 파마슈티컬스 인코포레이티드 안지오포이에틴-유사 3 (ANGPTL3)의 발현을 억제하기 위한 RNAi 작용제 및 조성물, 및 사용 방법
AR116566A1 (es) 2018-10-03 2021-05-19 Novartis Ag Administración sostenida de polipéptidos similares a la angiopoyetina 3
WO2020099482A2 (en) * 2018-11-13 2020-05-22 Lipigon Pharmaceuticals Ab Angptl 3 oligonucleotides influencing the regulation of the fatty acid metabolism
TWI747098B (zh) * 2018-12-21 2021-11-21 美商美國禮來大藥廠 抗angptl3/8複合物抗體及其使用方法
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CN110938144B (zh) * 2019-11-27 2022-07-26 复旦大学附属儿科医院 一种抗angptl3单克隆抗体及其在制备治疗肾病综合征药物中的用途
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CN114934021B (zh) * 2022-04-21 2023-08-08 复旦大学附属儿科医院 一种Angptl3敲除的鼠永生化足细胞系及其应用
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JP2010100624A (ja) 2010-05-06
IL161542A0 (en) 2004-09-27
IL203894A (en) 2013-09-30
US7267819B2 (en) 2007-09-11
CA2464542A1 (en) 2003-05-30
US20030215451A1 (en) 2003-11-20
EP1451578A2 (en) 2004-09-01
AU2002348286B2 (en) 2008-04-03
KR20100029861A (ko) 2010-03-17
WO2003044172A2 (en) 2003-05-30
US8541376B2 (en) 2013-09-24
JP5105696B2 (ja) 2012-12-26
US20070134250A1 (en) 2007-06-14
CA2464542C (en) 2015-01-20
NO20042410L (no) 2004-06-09
AU2002348286A1 (en) 2003-06-10
EP1451578B1 (en) 2013-08-21
EP1451578A4 (en) 2006-02-01
CN1615440A (zh) 2005-05-11
US20090098117A1 (en) 2009-04-16
CN101905024A (zh) 2010-12-08
ES2429034T3 (es) 2013-11-12
ZA200403070B (en) 2005-06-29
NO336021B1 (no) 2015-04-20
WO2003044172A3 (en) 2003-11-20
MXPA04004609A (es) 2004-08-12
KR20050044485A (ko) 2005-05-12
NZ532852A (en) 2006-08-31
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JP2005521643A (ja) 2005-07-21

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