KR101001129B1 - 디벤즈옥세핀 유도체의 제조 방법 - Google Patents

디벤즈옥세핀 유도체의 제조 방법 Download PDF

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Publication number
KR101001129B1
KR101001129B1 KR1020077022592A KR20077022592A KR101001129B1 KR 101001129 B1 KR101001129 B1 KR 101001129B1 KR 1020077022592 A KR1020077022592 A KR 1020077022592A KR 20077022592 A KR20077022592 A KR 20077022592A KR 101001129 B1 KR101001129 B1 KR 101001129B1
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KR
South Korea
Prior art keywords
formula
general formula
atom
compound
compound represented
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KR1020077022592A
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English (en)
Korean (ko)
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KR20080011652A (ko
Inventor
고이치로 니시무라
마사히코 기누가와
Original Assignee
교와 핫꼬 기린 가부시키가이샤
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Publication of KR20080011652A publication Critical patent/KR20080011652A/ko
Application granted granted Critical
Publication of KR101001129B1 publication Critical patent/KR101001129B1/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/74—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C69/757—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/16—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions not involving the amino or carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/307—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/74—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C69/75—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring of acids with a six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/74—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C69/753—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring of polycyclic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D313/12—[b,e]-condensed

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
KR1020077022592A 2005-06-02 2006-06-02 디벤즈옥세핀 유도체의 제조 방법 KR101001129B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JPJP-P-2005-00162240 2005-06-02
JP2005162240 2005-06-02

Publications (2)

Publication Number Publication Date
KR20080011652A KR20080011652A (ko) 2008-02-05
KR101001129B1 true KR101001129B1 (ko) 2010-12-14

Family

ID=37481708

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020077022592A KR101001129B1 (ko) 2005-06-02 2006-06-02 디벤즈옥세핀 유도체의 제조 방법

Country Status (5)

Country Link
JP (1) JP5099830B2 (zh)
KR (1) KR101001129B1 (zh)
CN (1) CN101151256B (zh)
TW (1) TW200716588A (zh)
WO (1) WO2006129781A1 (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5139104B2 (ja) * 2007-02-16 2013-02-06 住友化学株式会社 ジベンゾオキセピン化合物の製造方法
ES2344242B1 (es) * 2007-02-16 2011-06-06 Sumitomo Chemical Company, Limited Metodo para la produccion de un compuesto de dibenzoxepina.
WO2011033532A1 (en) 2009-09-17 2011-03-24 Indoco Remedies Limited Process for preparation of olopatadine hydrochloride

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5821679A (ja) 1981-07-31 1983-02-08 メルク　エンド　カムパニー　インコーポレーテツド ジベンツ〔ｂ，ｅ〕オキセピン化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4282365A (en) * 1978-11-24 1981-08-04 Merck & Co., Inc. Dibenz[b,e]oxepin compounds
AU1624801A (en) * 1999-11-19 2001-05-30 Corvas International, Inc. Plasminogen activator inhibitor antagonists related applications
PT1477472E (pt) * 2002-02-21 2009-03-17 Asahi Kasei Pharma Corp Derivado de ácido fenilalcanóico substituído e sua utilização

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5821679A (ja) 1981-07-31 1983-02-08 メルク　エンド　カムパニー　インコーポレーテツド ジベンツ〔ｂ，ｅ〕オキセピン化合物

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Chemistry Letters, 1990, 12, pp.2181-2182
Journal of Medicinal Chemistry,1993,36(11),pp.1613-1618
Tetrahedron Letters, 1993, 34(51), pp.8353-8356

Also Published As

Publication number Publication date
KR20080011652A (ko) 2008-02-05
CN101151256B (zh) 2011-02-09
WO2006129781A1 (ja) 2006-12-07
CN101151256A (zh) 2008-03-26
JP5099830B2 (ja) 2012-12-19
TW200716588A (en) 2007-05-01
JPWO2006129781A1 (ja) 2009-01-08

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