KR100903922B1 - 에난티오머 이미다졸 화합물 제조방법 - Google Patents

에난티오머 이미다졸 화합물 제조방법 Download PDF

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Publication number
KR100903922B1
KR100903922B1 KR1020077005699A KR20077005699A KR100903922B1 KR 100903922 B1 KR100903922 B1 KR 100903922B1 KR 1020077005699 A KR1020077005699 A KR 1020077005699A KR 20077005699 A KR20077005699 A KR 20077005699A KR 100903922 B1 KR100903922 B1 KR 100903922B1
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KR
South Korea
Prior art keywords
group
sertaconazole mononitrate
mononitrate
sertaconazole
phase
Prior art date
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Expired - Fee Related
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KR1020077005699A
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English (en)
Korean (ko)
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KR20070042206A (ko
Inventor
아이네스 패트쉔
사비에르 캠프스
후안 살라레스
Original Assignee
페레르 인터내쇼날 에스.에이.
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Application filed by 페레르 인터내쇼날 에스.에이. filed Critical 페레르 인터내쇼날 에스.에이.
Publication of KR20070042206A publication Critical patent/KR20070042206A/ko
Application granted granted Critical
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
KR1020077005699A 2004-09-13 2005-09-13 에난티오머 이미다졸 화합물 제조방법 Expired - Fee Related KR100903922B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200402184A ES2249992B1 (es) 2004-09-13 2004-09-13 Un procedimiento para fabricar compuestos enantiomericos del imidazol.
ES200402184 2004-09-13

Publications (2)

Publication Number Publication Date
KR20070042206A KR20070042206A (ko) 2007-04-20
KR100903922B1 true KR100903922B1 (ko) 2009-06-19

Family

ID=35614444

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020077005699A Expired - Fee Related KR100903922B1 (ko) 2004-09-13 2005-09-13 에난티오머 이미다졸 화합물 제조방법

Country Status (23)

Country Link
US (1) US7626038B2 (https=)
EP (1) EP1794152B1 (https=)
JP (1) JP5048500B2 (https=)
KR (1) KR100903922B1 (https=)
CN (1) CN101023077B (https=)
AR (1) AR050931A1 (https=)
AT (1) ATE402171T1 (https=)
AU (1) AU2005284330B2 (https=)
BR (1) BRPI0515259A (https=)
CA (1) CA2577247C (https=)
DE (1) DE602005008454D1 (https=)
DK (1) DK1794152T3 (https=)
ES (1) ES2249992B1 (https=)
MX (1) MX2007002939A (https=)
NO (1) NO20071817L (https=)
PA (1) PA8645501A1 (https=)
PE (1) PE20060720A1 (https=)
PL (1) PL1794152T3 (https=)
PT (1) PT1794152E (https=)
RU (1) RU2413728C2 (https=)
TW (1) TWI405760B (https=)
UY (1) UY29115A1 (https=)
WO (1) WO2006029811A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8635593B2 (en) * 2008-05-13 2014-01-21 Hewlett-Packard Development Company, L.P. Dynamic autocompletion tool
CN112595803A (zh) * 2020-12-31 2021-04-02 海南海神同洲制药有限公司 一种硝酸舍他康唑乳膏的鉴别方法
CN113501815A (zh) * 2021-07-30 2021-10-15 海南海神同洲制药有限公司 一种硝酸舍他康唑晶型的制备方法
CN113501814A (zh) * 2021-07-30 2021-10-15 海南海神同洲制药有限公司 一种硝酸舍他康唑的纯化方法
CN113480517B (zh) * 2021-07-30 2022-09-09 海南海神同洲制药有限公司 3-溴甲基-7-氯苯并[b]噻吩的合成方法
CN113816947A (zh) * 2021-08-25 2021-12-21 海南海神同洲制药有限公司 一种硝酸舍他康唑的重结晶方法
CN113735843B (zh) * 2021-09-07 2023-05-26 海南海神同洲制药有限公司 一种低熔点硝酸舍他康唑的制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003068770A1 (en) 2002-02-11 2003-08-21 Ferrer Internacional S.A. R- (-) -1- [2- (7-CHLOROBENZO [b] THIOPHEN-3 -YL- METHOXY) -2- (2,4-DICHLOROPHENYL) -ETHYL] -1H-IMIDAZOLE

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1096361B (it) * 1978-05-18 1985-08-26 Recordati Chem Pharm Dibenzileteri sostituiti terapeuticamente attivi
JPS57169466A (en) * 1981-04-14 1982-10-19 Ota Seiyaku Kk Preparation of imidazole derivative
CA1250586A (en) 1984-02-02 1989-02-28 Manuel Raga 1h-imidazole derivatives and process for their production
US5135943A (en) * 1984-02-02 1992-08-04 Ferrer Internacional S.A. 1H-imidazole derivative compounds and pharmaceutical compositions containing the same
ES529608A0 (es) * 1984-02-02 1985-05-01 Ferrer Int Procedimiento de obtencion de nuevos derivados de 1h-imidazol
WO1996020939A1 (es) * 1995-01-04 1996-07-11 Ferrer Internacional, S.A. POLYMORFOS B Y C DE MONONITRATO DE 1-[2,4-DICLORO-β-[(7-CLOROBENZO[b]TIEN-3-IL)METOXI]FENETIL]IMIDAZOL
HUP0104657A3 (en) * 1998-12-24 2002-07-29 Astellas Pharma Inc Chuo Ku Imidazole compounds and pharmaceutical compositions containing them
CN1191250C (zh) * 2001-09-26 2005-03-02 河北省药物研究所 一种硝酸舍他康唑的合成方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003068770A1 (en) 2002-02-11 2003-08-21 Ferrer Internacional S.A. R- (-) -1- [2- (7-CHLOROBENZO [b] THIOPHEN-3 -YL- METHOXY) -2- (2,4-DICHLOROPHENYL) -ETHYL] -1H-IMIDAZOLE

Also Published As

Publication number Publication date
US7626038B2 (en) 2009-12-01
TWI405760B (zh) 2013-08-21
BRPI0515259A (pt) 2008-07-15
KR20070042206A (ko) 2007-04-20
CN101023077A (zh) 2007-08-22
MX2007002939A (es) 2007-04-27
AU2005284330A1 (en) 2006-03-23
AU2005284330B2 (en) 2011-01-06
ES2249992B1 (es) 2007-03-01
RU2413728C2 (ru) 2011-03-10
AR050931A1 (es) 2006-12-06
TW200621756A (en) 2006-07-01
PT1794152E (pt) 2008-10-24
PE20060720A1 (es) 2006-07-11
DK1794152T3 (da) 2008-11-17
WO2006029811A1 (en) 2006-03-23
PL1794152T3 (pl) 2008-12-31
EP1794152B1 (en) 2008-07-23
CA2577247C (en) 2011-07-05
UY29115A1 (es) 2005-11-30
EP1794152A1 (en) 2007-06-13
RU2007113921A (ru) 2008-10-20
JP2008512421A (ja) 2008-04-24
HK1105416A1 (en) 2008-02-15
DE602005008454D1 (de) 2008-09-04
PA8645501A1 (es) 2006-05-16
CA2577247A1 (en) 2006-03-23
US20080108682A1 (en) 2008-05-08
CN101023077B (zh) 2012-05-23
NO20071817L (no) 2007-05-16
JP5048500B2 (ja) 2012-10-17
ES2249992A1 (es) 2006-04-01
ATE402171T1 (de) 2008-08-15

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