KR100873819B1 - 근육 손상의 처치방법 - Google Patents
근육 손상의 처치방법 Download PDFInfo
- Publication number
- KR100873819B1 KR100873819B1 KR1020037004676A KR20037004676A KR100873819B1 KR 100873819 B1 KR100873819 B1 KR 100873819B1 KR 1020037004676 A KR1020037004676 A KR 1020037004676A KR 20037004676 A KR20037004676 A KR 20037004676A KR 100873819 B1 KR100873819 B1 KR 100873819B1
- Authority
- KR
- South Korea
- Prior art keywords
- muscle
- botulinum toxin
- bont
- injured
- neurotoxin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
- A61K38/4893—Botulinum neurotoxin (3.4.24.69)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/08—Clostridium, e.g. Clostridium tetani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/678,189 | 2000-10-04 | ||
| US09/678,189 US6423319B1 (en) | 2000-10-04 | 2000-10-04 | Methods for treating muscle injuries |
| PCT/US2001/027193 WO2002028425A2 (en) | 2000-10-04 | 2001-08-31 | Methods for treating muscle injuries |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20030043981A KR20030043981A (ko) | 2003-06-02 |
| KR100873819B1 true KR100873819B1 (ko) | 2008-12-11 |
Family
ID=24721759
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020037004676A Expired - Lifetime KR100873819B1 (ko) | 2000-10-04 | 2001-08-31 | 근육 손상의 처치방법 |
Country Status (16)
| Country | Link |
|---|---|
| US (4) | US6423319B1 (enExample) |
| EP (2) | EP1322324B1 (enExample) |
| JP (2) | JP2004518632A (enExample) |
| KR (1) | KR100873819B1 (enExample) |
| CN (2) | CN102078597A (enExample) |
| AT (1) | ATE477816T1 (enExample) |
| AU (2) | AU2001286991B2 (enExample) |
| BR (1) | BR0114440A (enExample) |
| CA (1) | CA2424242C (enExample) |
| DE (1) | DE60142839D1 (enExample) |
| DK (1) | DK1322324T3 (enExample) |
| ES (1) | ES2348862T3 (enExample) |
| MX (1) | MXPA03002576A (enExample) |
| NZ (1) | NZ524793A (enExample) |
| TW (1) | TWI292713B (enExample) |
| WO (1) | WO2002028425A2 (enExample) |
Families Citing this family (134)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060216313A1 (en) * | 1999-08-10 | 2006-09-28 | Allergan, Inc. | Methods for treating a stricture with a botulinum toxin |
| US7838008B2 (en) * | 1999-12-07 | 2010-11-23 | Allergan, Inc. | Methods for treating diverse cancers |
| US20040170665A1 (en) * | 2000-06-02 | 2004-09-02 | Allergan, Inc. | Intravitreal botulinum toxin implant |
| US20040033241A1 (en) * | 2000-06-02 | 2004-02-19 | Allergan, Inc. | Controlled release botulinum toxin system |
| US7491799B2 (en) * | 2000-07-21 | 2009-02-17 | Allergan, Inc. | Modified botulinum neurotoxins |
| US7691983B2 (en) * | 2000-07-21 | 2010-04-06 | Allergan, Inc. | Chimera botulinum toxin type E |
| US20040219619A1 (en) * | 2000-07-21 | 2004-11-04 | Ester Fernandez-Salas | Methods of identifying compounds that alter toxin persistence and/or protease activity |
| US6903187B1 (en) * | 2000-07-21 | 2005-06-07 | Allergan, Inc. | Leucine-based motif and clostridial neurotoxins |
| US6423319B1 (en) * | 2000-10-04 | 2002-07-23 | Allergan Sales, Inc. | Methods for treating muscle injuries |
| ITUD20010002A1 (it) * | 2001-01-05 | 2002-07-05 | Univ Degli Studi Udine | Uso della tossina botulinica per la soluzione di patologie articolari, in particolare della coxartrosi, della epicondilite e della patolo |
| JP4707254B2 (ja) * | 2001-04-24 | 2011-06-22 | クミアイ化学工業株式会社 | 粒状組成物及びその製造方法 |
| WO2003000193A2 (en) * | 2001-06-21 | 2003-01-03 | Surromed, Inc. | Covalent coupling of botulinum toxin with polyethylene glycol |
| EP1443932B1 (en) * | 2001-11-15 | 2012-12-26 | Micro Algae Corporation | Pharmaceutical compositions containing 3,4-propinoperhydropurines and uses thereof for blocking neuronal transmission |
| US7140371B2 (en) * | 2002-03-14 | 2006-11-28 | Allergan, Inc. | Surface topography method for determining effects of a botulinum toxin upon a muscle and for comparing botulinum toxins |
| US7300412B2 (en) * | 2002-05-10 | 2007-11-27 | Hospital For Joint Diseases | Methods for therapeutic treatment of carpal tunnel syndrome |
| WO2004012674A2 (en) * | 2002-08-02 | 2004-02-12 | Nutraceutical Development Corporation | Development of muscle mass in a mammal |
| US20040037895A1 (en) * | 2002-08-23 | 2004-02-26 | Alex Zhu | Methods of treating involuntary facial spasms and facial wrinkles |
| US20040115139A1 (en) * | 2002-10-15 | 2004-06-17 | Allergan, Inc. | Botulinum toxin dental therapies and procedures |
| US7238357B2 (en) * | 2002-11-05 | 2007-07-03 | Allergan, Inc. | Methods for treating ulcers and gastroesophageal reflux disease |
| US20040086532A1 (en) * | 2002-11-05 | 2004-05-06 | Allergan, Inc., | Botulinum toxin formulations for oral administration |
| ZA200506715B (en) * | 2003-03-06 | 2007-05-30 | Botulinum Toxin Res Ass Inc | Treatment of sinusitis related chronic facial pain and headache with botulinum toxin |
| US7390496B2 (en) * | 2003-04-25 | 2008-06-24 | Allergan, Inc. | Therapeutic treatments for repetitive hand washing |
| US7396535B2 (en) * | 2003-04-25 | 2008-07-08 | Ackerman Alan H | Therapy for obsessive compulsive head banging |
| US7393538B2 (en) * | 2003-04-25 | 2008-07-01 | Ackerman Alan H | Clostridial toxin treatment for dermatillomania |
| US7422753B2 (en) * | 2003-04-25 | 2008-09-09 | Allergan, Inc. | Methods for treating trichotillomania |
| US7393537B2 (en) * | 2003-04-25 | 2008-07-01 | Allergan, Inc. | Botulinum toxin for treatment of obsessive compulsive finger biting disorder |
| US6838434B2 (en) * | 2003-05-02 | 2005-01-04 | Allergan, Inc. | Methods for treating sinus headache |
| US7220422B2 (en) * | 2003-05-20 | 2007-05-22 | Allergan, Inc. | Methods and compositions for treating eye disorders |
| US20040253274A1 (en) * | 2003-06-11 | 2004-12-16 | Allergan, Inc. | Use of a clostridial toxin to reduce appetite |
| US20050013850A1 (en) * | 2003-07-15 | 2005-01-20 | Caers Jan K. | Device to assist hyperhydrosis therapy |
| US8609113B2 (en) | 2003-10-29 | 2013-12-17 | Allergan, Inc. | Botulinum toxin treatments of depression |
| US8734810B2 (en) | 2003-10-29 | 2014-05-27 | Allergan, Inc. | Botulinum toxin treatments of neurological and neuropsychiatric disorders |
| US8609112B2 (en) | 2003-10-29 | 2013-12-17 | Allergan, Inc. | Botulinum toxin treatments of depression |
| US8617572B2 (en) | 2003-10-29 | 2013-12-31 | Allergan, Inc. | Botulinum toxin treatments of depression |
| US7172764B2 (en) * | 2003-11-17 | 2007-02-06 | Allergan, Inc. | Rescue agents for treating botulinum toxin intoxications |
| US8871224B2 (en) | 2003-12-09 | 2014-10-28 | Allergan, Inc. | Botulinum toxin therapy for skin disorders |
| US8048423B2 (en) * | 2003-12-09 | 2011-11-01 | Allergan, Inc. | Botulinum toxin therapy for skin disorders |
| US20050129677A1 (en) * | 2003-12-10 | 2005-06-16 | Shengwen Li | Lipid rafts and clostridial toxins |
| US20050148935A1 (en) * | 2003-12-29 | 2005-07-07 | Rozalina Dimitrova | Botulinum toxin injection guide |
| US7270287B2 (en) * | 2004-01-06 | 2007-09-18 | Allergan, Inc. | Botulinum toxin treatment for kinesia |
| US6974579B2 (en) * | 2004-01-08 | 2005-12-13 | Allergan, Inc. | Methods for treating vascular disorders |
| US9078892B2 (en) * | 2004-02-26 | 2015-07-14 | Allergan, Inc. | Methods for treating pain and for treating a medication overuse disorder |
| US20050191321A1 (en) | 2004-02-26 | 2005-09-01 | Allergan, Inc. | Methods for treating headache |
| US20100266638A1 (en) * | 2004-02-26 | 2010-10-21 | Allergan, Inc. | Headache treatment method |
| US9211248B2 (en) | 2004-03-03 | 2015-12-15 | Revance Therapeutics, Inc. | Compositions and methods for topical application and transdermal delivery of botulinum toxins |
| US20050220821A1 (en) * | 2004-03-31 | 2005-10-06 | Allergan, Inc. | Pressure sore treatment |
| US20050220734A1 (en) * | 2004-04-02 | 2005-10-06 | Allergan, Inc. | Therapy for melanin related afflictions |
| BRPI0510761A (pt) * | 2004-05-07 | 2007-11-20 | Phytotox Ltd | métodos de tratar um paciente afligido com pelo menos uma enfermidade e de reduzir ou eliminar rugas |
| EP1796676B1 (en) * | 2004-05-07 | 2016-03-09 | Phytotox Limited | Transdermal administration of phycotoxins |
| US6991789B2 (en) * | 2004-06-29 | 2006-01-31 | Allergas, Inc. | Methods of modulating intracellular degradation rates of toxins |
| US7514088B2 (en) * | 2005-03-15 | 2009-04-07 | Allergan, Inc. | Multivalent Clostridial toxin derivatives and methods of their use |
| US7922983B2 (en) * | 2005-07-28 | 2011-04-12 | Kimberly-Clark Worldwide, Inc. | Sterilization wrap with additional strength sheet |
| US7811584B2 (en) * | 2004-06-30 | 2010-10-12 | Allergan, Inc. | Multivalent clostridial toxins |
| US20060024794A1 (en) * | 2004-07-30 | 2006-02-02 | Shengwen Li | Novel methods for production of di-chain botulinum toxin |
| US20060024331A1 (en) * | 2004-08-02 | 2006-02-02 | Ester Fernandez-Salas | Toxin compounds with enhanced membrane translocation characteristics |
| EP1982997B1 (en) | 2004-09-01 | 2012-08-08 | Allergan, Inc. | Degradable clostridial toxins |
| US7179474B2 (en) * | 2004-09-03 | 2007-02-20 | Allergan, Inc. | Methods for treating a buttock deformity |
| US7429386B2 (en) * | 2004-09-03 | 2008-09-30 | Allergan, Inc. | Stretch mark treatment |
| US20060073208A1 (en) * | 2004-10-01 | 2006-04-06 | Allergan, Inc. | Cosmetic neurotoxin compositions and methods |
| US7897147B2 (en) * | 2004-10-20 | 2011-03-01 | Allergan, Inc. | Treatment of premenstrual disorders |
| US7655244B2 (en) | 2005-02-01 | 2010-02-02 | Allergan, Inc. | Targeted delivery of botulinum toxin for the treatment and prevention of trigeminal autonomic cephalgias, migraine and vascular conditions |
| US7749515B2 (en) | 2005-02-01 | 2010-07-06 | Allergan, Inc. | Targeted delivery of botulinum toxin to the sphenopalatine ganglion |
| KR20070116710A (ko) | 2005-03-03 | 2007-12-11 | 알러간, 인코포레이티드 | 보툴리눔 독소를 정제하기 위한 동물 산물이 없는 시스템및 프로세스 |
| JP2008535486A (ja) | 2005-03-15 | 2008-09-04 | アラーガン、インコーポレイテッド | クロストリジウム毒素標的細胞に対する改変された標的能力を有する修飾クロストリジウム毒素 |
| ES2351942T3 (es) | 2005-04-05 | 2011-02-14 | Allergan Inc | Analisis de la actividad de una toxina clostridial. |
| US7419675B2 (en) * | 2005-05-26 | 2008-09-02 | Allergan, Inc. | Method for treating peritoneal adhesions |
| WO2006129171A2 (en) * | 2005-05-31 | 2006-12-07 | Polydoor Emile Huijsmans | Method and medical package for repairing tendons by surgery |
| US20060269574A1 (en) * | 2005-05-31 | 2006-11-30 | De Beer Johann F | Method of repairing tendons by surgery |
| US8105611B2 (en) | 2005-06-17 | 2012-01-31 | Allergan, Inc. | Treatment of autoimmune disorder with a neurotoxin |
| US7910116B2 (en) * | 2005-08-24 | 2011-03-22 | Allergan, Inc. | Use of a botulinum toxin to improve gastric emptying and/or to treat GERD |
| US7824694B2 (en) * | 2006-01-12 | 2010-11-02 | Allergan, Inc. | Methods for enhancing therapeutic effects of a neurotoxin |
| US20070178121A1 (en) * | 2006-01-27 | 2007-08-02 | Allergan, Inc. | Methods for enhancing skin treatments |
| US7794386B2 (en) | 2006-03-15 | 2010-09-14 | Allergan, Inc. | Methods for facilitating weight loss |
| US7811586B2 (en) * | 2006-05-02 | 2010-10-12 | Allergan, Inc. | Methods for alleviating testicular pain |
| CN101074935B (zh) * | 2006-05-19 | 2011-03-23 | 清华大学 | 探测器阵列及设备 |
| US9061025B2 (en) * | 2006-08-31 | 2015-06-23 | Allergan, Inc. | Methods for selecting headache patients responsive to botulinum toxin therapy |
| US20080092910A1 (en) * | 2006-10-18 | 2008-04-24 | Allergan, Inc. | Apparatus and method for treating obesity using neurotoxins in conjunction with bariatric procedures |
| US20080113051A1 (en) * | 2006-11-13 | 2008-05-15 | Allergan, Inc. | Methods for alleviating tattoo pain |
| ES2441961T3 (es) | 2007-02-15 | 2014-02-07 | Allergan, Inc. | Composiciones de toxina botulínica y métodos |
| US8470337B2 (en) * | 2008-03-13 | 2013-06-25 | Allergan, Inc. | Therapeutic treatments using botulinum neurotoxin |
| US8617571B2 (en) | 2008-04-03 | 2013-12-31 | Allergan, Inc. | Suture line administration technique using botulinum toxin |
| ES2356883B1 (es) * | 2008-07-24 | 2012-02-22 | Bcn Peptides, S.A. | Composición para el tratamiento del dolor y/o la inflamación. |
| US20100028385A1 (en) * | 2008-08-04 | 2010-02-04 | Allergan, Inc. | Treatment of excess cerumen secretion |
| US9072779B2 (en) | 2009-01-07 | 2015-07-07 | Robert John Petrella | Treatment of soft tissue injury using hyaluronic acid and botulinum toxin |
| CA2754423A1 (en) | 2009-03-06 | 2010-09-10 | Allergan, Inc. | Clostridial toxin to improve ejaculate |
| WO2011038015A1 (en) | 2009-09-24 | 2011-03-31 | Allergan, Inc. | Method of treating osteoporosis with a neurotoxin |
| JP2011157331A (ja) * | 2010-02-03 | 2011-08-18 | Chemo-Sero-Therapeutic Research Inst | 高用量投与が可能なボツリヌス毒素製剤 |
| US20120195878A1 (en) | 2011-01-28 | 2012-08-02 | Allergan, Inc. | Protocol for the administration of botulinum toxins |
| US8697090B2 (en) | 2011-05-05 | 2014-04-15 | Allergan, Inc. | Method of treating persistent genital arousal disorder with a neurotoxin |
| WO2013009625A1 (en) | 2011-07-08 | 2013-01-17 | Allergan, Inc. | Method for treatment of autonomic nervous system disorders |
| US8992941B2 (en) | 2011-07-08 | 2015-03-31 | Allergan, Inc. | Method for treatment of esophageal spasm |
| CA2841917A1 (en) | 2011-07-14 | 2013-01-17 | Allergan, Inc. | Methods for treatment of incontinence associated with sexual activity |
| AU2012283968B2 (en) | 2011-07-20 | 2016-04-14 | Allergan, Inc. | Botulinum toxins for use in a method for treatment of adipose deposits |
| US9138188B2 (en) * | 2011-07-20 | 2015-09-22 | Joseph C. McGinley | Method for treating and confirming diagnosis of exertional compartment syndrome |
| US9226954B2 (en) | 2011-07-20 | 2016-01-05 | Joseph C. McGinley | Method for treating and confirming diagnosis of exertional compartment syndrome |
| ES2424294B1 (es) | 2012-03-22 | 2014-07-21 | Lipotec, S.A. | Exopolisacárido para el tratamiento y/o cuidado de la piel, mucosas, cabello y/o uñas |
| EP2649985A1 (en) | 2012-04-13 | 2013-10-16 | Lipotec, S.A. | Compounds which inhibit neuronal exocytosis (III) |
| EP2649983A1 (en) | 2012-04-13 | 2013-10-16 | Lipotec, S.A. | Compounds which inhibit neuronal exocytosis (II) |
| EP2649984A1 (en) | 2012-04-13 | 2013-10-16 | Lipotec, S.A. | Compounds which inhibit neuronal exocytosis |
| EP2836193B1 (en) | 2012-04-13 | 2018-01-31 | Lubrizol Advanced Materials, Inc. | Compounds which inhibit neuronal exocytosis (ii) |
| US9138194B1 (en) | 2012-06-27 | 2015-09-22 | Joseph McGinley | Apparatus for use to replicate symptoms associated with vascular obstruction secondary to vascular compression |
| US9005628B2 (en) | 2012-10-04 | 2015-04-14 | Dublin City University | Biotherapy for pain |
| BR112015024221A2 (pt) | 2013-03-22 | 2017-07-18 | Lipotec Sa | exopolissacarídeo, uso do exopolissacarídeio, e, composição cosmética ou dermofarmacêutica |
| GB201312317D0 (en) | 2013-07-09 | 2013-08-21 | Syntaxin Ltd | Cationic neurotoxins |
| US10149893B2 (en) | 2013-09-24 | 2018-12-11 | Allergan, Inc. | Methods for modifying progression of osteoarthritis |
| US9480731B2 (en) | 2013-12-12 | 2016-11-01 | Medy-Tox, Inc. | Long lasting effect of new botulinum toxin formulations |
| US9216210B2 (en) | 2013-12-23 | 2015-12-22 | Dublin City University | Multiprotease therapeutics for chronic pain |
| US10058471B2 (en) * | 2014-02-21 | 2018-08-28 | William M. Vaughan | System and method of using hyperbaric oxygen therapy for treating concussive symptoms and musculoskeletal injuries and for pre-treatment to prevent damage from injuries |
| WO2015188942A1 (en) * | 2014-06-13 | 2015-12-17 | Merz Pharma Gmbh & Co. Kgaa | Novel uses of recombinant clostridial neurotoxins with decreased duration of effect |
| WO2015188944A1 (en) * | 2014-06-13 | 2015-12-17 | Merz Pharma Gmbh & Co. Kgaa | Novel uses of recombinant clostridial neurotoxins with decreased duration of effect |
| DK3242884T3 (da) | 2015-01-09 | 2021-04-19 | Ipsen Bioinnovation Ltd | Kationiske neurotoksiner |
| GB201517450D0 (en) | 2015-10-02 | 2015-11-18 | Ipsen Biopharm Ltd | Method |
| CN105567739B (zh) * | 2016-02-04 | 2019-07-12 | 郑州可尔利尔生物科技有限公司 | 病毒载体颗粒及其构建方法和应用 |
| KR20180130104A (ko) * | 2016-03-25 | 2018-12-06 | 입센 바이오팜 리미티드 | 보툴리눔 독소의 치료 효능을 증진시키기 위한 물리 요법 정보의 수집 |
| GB201607901D0 (en) | 2016-05-05 | 2016-06-22 | Ipsen Biopharm Ltd | Chimeric neurotoxins |
| EP3263710A1 (en) | 2016-07-01 | 2018-01-03 | Ipsen Biopharm Limited | Production of activated clostridial neurotoxins |
| WO2018038301A1 (en) | 2016-08-26 | 2018-03-01 | Hugel Inc. | Stabilized liquid formulation of botulinum toxin and preparation method thereof |
| WO2018060351A1 (en) | 2016-09-29 | 2018-04-05 | Ipsen Biopharm Limited | Hybrid neurotoxins |
| WO2018106339A1 (en) * | 2016-12-06 | 2018-06-14 | Bonti, Inc. | Botulinum neurotoxins for use in tendon repair surgery |
| US20200023044A1 (en) * | 2017-03-22 | 2020-01-23 | Bonti, Inc. | Botulinum neurotoxins for treating traumatic injuries |
| AU2018254588A1 (en) * | 2017-04-21 | 2019-11-07 | Bonti, Inc. | Initiating neurotoxin treatments |
| EP3470054B1 (en) | 2017-10-11 | 2023-09-20 | Hugel Inc. | Microstructure formulation techniques for botulinum toxin |
| US10792400B2 (en) | 2017-10-12 | 2020-10-06 | Hugel Inc. | Microstructure formulation techniques for botulinum toxin |
| US10525111B2 (en) | 2017-10-12 | 2020-01-07 | Hugel, Inc. | Microstructure formulation techniques for botulinum toxin |
| EP3758611B1 (en) | 2018-02-26 | 2024-07-24 | Ipsen Biopharm Limited | Ultrasound apparatus to guide injection of non-cytotoxic protease |
| WO2020056204A1 (en) * | 2018-09-13 | 2020-03-19 | Allergan, Inc. | Methods for treatment of masseter muscle hypertrophy |
| EP3660509B1 (en) | 2018-11-29 | 2022-03-09 | Hugel Inc. | A cell-based method for determining an activity of botulinum toxin |
| US20220096609A1 (en) * | 2019-02-06 | 2022-03-31 | Allergan, Inc. | Combination therapy using clostridial toxin derivative and at least one chemical depolarizing agent |
| CN110710494B (zh) * | 2019-10-20 | 2021-06-11 | 宋凯 | 一种眼睛王蛇毒液安全取出装置 |
| JP2022040051A (ja) | 2020-08-27 | 2022-03-10 | ユニテックフーズ株式会社 | 筋損傷回復促進用組成物 |
| GB202103372D0 (en) | 2021-03-11 | 2021-04-28 | Ipsen Biopharm Ltd | Modified clostridial neurotoxins |
| AU2023351434A1 (en) | 2022-09-30 | 2025-03-06 | Ipsen Biopharm Limited | Clostridial neurotoxin for use in a treatment of bladder pain syndrome |
| GB202318884D0 (en) | 2023-12-11 | 2024-01-24 | Ipsen Biopharm Ltd | Formulation |
| CN120168615B (zh) * | 2025-05-20 | 2025-08-26 | 浙江大学医学院附属第二医院 | A型肉毒毒素在制备减轻尖吻蝮蛇咬伤后肢体局部肌肉损伤药物中的应用及药物 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU6030494A (en) | 1993-01-15 | 1994-08-15 | Associated Synapse Biologics | Method for treating myofascial pain syndrome |
| CA2164626C (en) * | 1993-06-10 | 2004-11-23 | K. Roger Aoki | Multiple botulinum toxins for treating neuromuscular disorders and conditions |
| ATE181482T1 (de) | 1993-12-22 | 1999-07-15 | Zeneca Ltd | Herbizide zusammensetzungen in form einer diphenylether- und stickstofflösung und verfahren |
| EP1790352B1 (en) * | 1993-12-28 | 2008-07-09 | Allergan, Inc. | Use of botulinum toxin for the manufacture of a medicament for reducing low back pain |
| US6203794B1 (en) | 1994-05-31 | 2001-03-20 | Allergan Sales, Inc. | Modification of clostridial toxins for use as transport proteins |
| US5721215A (en) | 1996-03-20 | 1998-02-24 | Allergan | Injectable therapy for control of muscle spasms and pain related to muscle spasms |
| US6063768A (en) * | 1997-09-04 | 2000-05-16 | First; Eric R. | Application of botulinum toxin to the management of neurogenic inflammatory disorders |
| GB9818548D0 (en) * | 1998-08-25 | 1998-10-21 | Microbiological Res Authority | Treatment of mucas hypersecretion |
| KR20010089347A (ko) * | 1998-10-27 | 2001-10-06 | 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 | 상처 치료 증진 방법 |
| US7138127B1 (en) * | 2000-01-19 | 2006-11-21 | Allergan, Inc. | Clostridial toxin derivatives and methods for treating pain |
| EP1514556B1 (en) * | 2000-02-08 | 2011-08-10 | Allergan, Inc. | Botulinum toxin pharmaceutical compositions |
| US6464986B1 (en) * | 2000-04-14 | 2002-10-15 | Allegan Sales, Inc. | Method for treating pain by peripheral administration of a neurotoxin |
| US6423319B1 (en) * | 2000-10-04 | 2002-07-23 | Allergan Sales, Inc. | Methods for treating muscle injuries |
| DE10131388B4 (de) * | 2001-06-28 | 2004-07-08 | Infineon Technologies Ag | Integrierter dynamischer Speicher und Verfahren zum Betrieb desselben |
-
2000
- 2000-10-04 US US09/678,189 patent/US6423319B1/en not_active Expired - Lifetime
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2001
- 2001-08-31 KR KR1020037004676A patent/KR100873819B1/ko not_active Expired - Lifetime
- 2001-08-31 DE DE60142839T patent/DE60142839D1/de not_active Expired - Lifetime
- 2001-08-31 CA CA002424242A patent/CA2424242C/en not_active Expired - Lifetime
- 2001-08-31 NZ NZ524793A patent/NZ524793A/en not_active IP Right Cessation
- 2001-08-31 EP EP01966482A patent/EP1322324B1/en not_active Revoked
- 2001-08-31 MX MXPA03002576A patent/MXPA03002576A/es active IP Right Grant
- 2001-08-31 AU AU2001286991A patent/AU2001286991B2/en not_active Ceased
- 2001-08-31 DK DK01966482.0T patent/DK1322324T3/da active
- 2001-08-31 JP JP2002532249A patent/JP2004518632A/ja active Pending
- 2001-08-31 CN CN2010106210202A patent/CN102078597A/zh active Pending
- 2001-08-31 BR BR0114440-5A patent/BR0114440A/pt not_active IP Right Cessation
- 2001-08-31 ES ES01966482T patent/ES2348862T3/es not_active Expired - Lifetime
- 2001-08-31 AT AT01966482T patent/ATE477816T1/de not_active IP Right Cessation
- 2001-08-31 EP EP10150415A patent/EP2174662A3/en not_active Withdrawn
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- 2001-08-31 WO PCT/US2001/027193 patent/WO2002028425A2/en not_active Ceased
- 2001-09-07 TW TW090122250A patent/TWI292713B/zh not_active IP Right Cessation
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2002
- 2002-05-23 US US10/155,925 patent/US6955813B2/en not_active Expired - Lifetime
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2004
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2006
- 2006-08-22 US US11/507,708 patent/US7468188B2/en not_active Expired - Fee Related
-
2012
- 2012-07-27 JP JP2012166469A patent/JP2012229263A/ja active Pending
Non-Patent Citations (1)
| Title |
|---|
| British Medical Journal, Vol. 319, No. 7228, pp. 161-165(2000년 1월 15일)* |
Also Published As
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| CN1658897A (zh) | 2005-08-24 |
| KR20030043981A (ko) | 2003-06-02 |
| US20070128227A1 (en) | 2007-06-07 |
| EP2174662A3 (en) | 2010-06-30 |
| DE60142839D1 (de) | 2010-09-30 |
| JP2012229263A (ja) | 2012-11-22 |
| EP2174662A2 (en) | 2010-04-14 |
| WO2002028425A3 (en) | 2003-02-27 |
| US6423319B1 (en) | 2002-07-23 |
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| CA2424242A1 (en) | 2002-04-11 |
| BR0114440A (pt) | 2004-06-15 |
| US7108857B2 (en) | 2006-09-19 |
| CN102078597A (zh) | 2011-06-01 |
| AU2001286991B2 (en) | 2005-05-19 |
| NZ524793A (en) | 2005-09-30 |
| US6955813B2 (en) | 2005-10-18 |
| US7468188B2 (en) | 2008-12-23 |
| TWI292713B (en) | 2008-01-21 |
| AU8699101A (en) | 2002-04-15 |
| US20020192240A1 (en) | 2002-12-19 |
| JP2004518632A (ja) | 2004-06-24 |
| DK1322324T3 (da) | 2010-11-01 |
| ATE477816T1 (de) | 2010-09-15 |
| MXPA03002576A (es) | 2004-04-20 |
| EP1322324A2 (en) | 2003-07-02 |
| EP1322324B1 (en) | 2010-08-18 |
| ES2348862T3 (es) | 2010-12-16 |
| WO2002028425A2 (en) | 2002-04-11 |
| US20050281846A1 (en) | 2005-12-22 |
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