KR100840393B1 - 조절된 방출용 약학 제형에 사용하기 위한 가교결합된 고아밀로오스 전분 및 이의 제조 방법 - Google Patents

조절된 방출용 약학 제형에 사용하기 위한 가교결합된 고아밀로오스 전분 및 이의 제조 방법 Download PDF

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Publication number
KR100840393B1
KR100840393B1 KR1020027018039A KR20027018039A KR100840393B1 KR 100840393 B1 KR100840393 B1 KR 100840393B1 KR 1020027018039 A KR1020027018039 A KR 1020027018039A KR 20027018039 A KR20027018039 A KR 20027018039A KR 100840393 B1 KR100840393 B1 KR 100840393B1
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South Korea
Prior art keywords
starch
high amylose
amylose starch
slurry
controlled release
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KR1020027018039A
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English (en)
Korean (ko)
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KR20030031504A (ko
Inventor
빈센트 레나르트
롤렌드 헤위그 프리드리히 벡
엘지에 반 보가르트
프란코스 초우나르드
라이너 홉케
크릴 데제바욱스
Original Assignee
빈센트 레나르트
프란코스 초우나르드
롤렌드 헤위그 프리드리히 벡
크릴 데제바욱스
엘지에 반 보가르트
라이너 홉케
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Application filed by 빈센트 레나르트, 프란코스 초우나르드, 롤렌드 헤위그 프리드리히 벡, 크릴 데제바욱스, 엘지에 반 보가르트, 라이너 홉케 filed Critical 빈센트 레나르트
Publication of KR20030031504A publication Critical patent/KR20030031504A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B33/00—Preparation of derivatives of amylose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020027018039A 2000-06-29 2001-06-26 조절된 방출용 약학 제형에 사용하기 위한 가교결합된 고아밀로오스 전분 및 이의 제조 방법 KR100840393B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/606,399 2000-06-29
US09/606,399 US6607748B1 (en) 2000-06-29 2000-06-29 Cross-linked high amylose starch for use in controlled-release pharmaceutical formulations and processes for its manufacture
PCT/US2001/020319 WO2002002084A1 (en) 2000-06-29 2001-06-26 Cross-linked high amylose starch for use in controlled-release pharmaceutical formulations and processes for its manufacture

Publications (2)

Publication Number Publication Date
KR20030031504A KR20030031504A (ko) 2003-04-21
KR100840393B1 true KR100840393B1 (ko) 2008-06-23

Family

ID=24427807

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KR1020027018039A KR100840393B1 (ko) 2000-06-29 2001-06-26 조절된 방출용 약학 제형에 사용하기 위한 가교결합된 고아밀로오스 전분 및 이의 제조 방법

Country Status (27)

Country Link
US (2) US6607748B1 (pt)
EP (1) EP1305009B1 (pt)
JP (1) JP5025066B2 (pt)
KR (1) KR100840393B1 (pt)
CN (1) CN100352509C (pt)
AR (1) AR029549A1 (pt)
AT (1) ATE328585T1 (pt)
AU (2) AU2001271481B2 (pt)
BR (1) BRPI0112140B8 (pt)
CA (1) CA2414349C (pt)
CZ (1) CZ300152B6 (pt)
DE (1) DE60120413T2 (pt)
DK (1) DK1305009T3 (pt)
ES (1) ES2272499T3 (pt)
HK (1) HK1059574A1 (pt)
HU (1) HUP0301302A2 (pt)
IL (2) IL153654A0 (pt)
MX (1) MXPA03000035A (pt)
MY (1) MY128308A (pt)
NO (1) NO20026254L (pt)
NZ (1) NZ523644A (pt)
PL (1) PL202177B1 (pt)
PT (1) PT1305009E (pt)
RU (1) RU2274443C2 (pt)
SI (1) SI1305009T1 (pt)
TW (1) TWI289460B (pt)
WO (1) WO2002002084A1 (pt)

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