KR100763298B1 - 선택적인 ｋｄｒ 및 ｆｇｆｒ 저해제로서의피리디노［２,３－ｄ］피리미딘 유도체 - Google Patents

선택적인 ｋｄｒ 및 ｆｇｆｒ 저해제로서의피리디노［２,３－ｄ］피리미딘 유도체 Download PDF

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KR100763298B1
KR100763298B1 KR1020057011681A KR20057011681A KR100763298B1 KR 100763298 B1 KR100763298 B1 KR 100763298B1 KR 1020057011681 A KR1020057011681 A KR 1020057011681A KR 20057011681 A KR20057011681 A KR 20057011681A KR 100763298 B1 KR100763298 B1 KR 100763298B1
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phenyl
pyrimidin
propionic acid
methoxy
formula
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KR20050088202A (ko
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진-쥔 류
킨-춘 뤽
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에프. 호프만-라 로슈 아게
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KR1020057011681A 2002-12-20 2003-12-11 선택적인 ｋｄｒ 및 ｆｇｆｒ 저해제로서의피리디노［２,３－ｄ］피리미딘 유도체 Expired - Fee Related KR100763298B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US43496902P 2002-12-20 2002-12-20
US60/434,969 2002-12-20
US51361503P 2003-10-23 2003-10-23
US60/513,615 2003-10-23

Publications (2)

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KR20050088202A KR20050088202A (ko) 2005-09-02
KR100763298B1 true KR100763298B1 (ko) 2007-10-04

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US (1) US7098332B2 (https=)
EP (1) EP1581531B1 (https=)
JP (1) JP2006511563A (https=)
KR (1) KR100763298B1 (https=)
AR (1) AR042532A1 (https=)
AT (1) ATE387445T1 (https=)
AU (1) AU2003294830B2 (https=)
BR (1) BR0317480A (https=)
CA (1) CA2508951A1 (https=)
DE (1) DE60319430T2 (https=)
ES (1) ES2300639T3 (https=)
MX (1) MXPA05006437A (https=)
PL (1) PL377661A1 (https=)
RU (1) RU2345077C2 (https=)
WO (1) WO2004056822A1 (https=)

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RU2345077C2 (ru) 2009-01-27
AU2003294830A1 (en) 2004-07-14
ATE387445T1 (de) 2008-03-15
US20040122029A1 (en) 2004-06-24
ES2300639T3 (es) 2008-06-16
CA2508951A1 (en) 2004-07-08
RU2005122901A (ru) 2006-02-27
DE60319430T2 (de) 2009-02-26
MXPA05006437A (es) 2005-08-19
EP1581531A1 (en) 2005-10-05
JP2006511563A (ja) 2006-04-06
KR20050088202A (ko) 2005-09-02
DE60319430D1 (de) 2008-04-10
US7098332B2 (en) 2006-08-29
WO2004056822A1 (en) 2004-07-08
PL377661A1 (pl) 2006-02-06
EP1581531B1 (en) 2008-02-27
AR042532A1 (es) 2005-06-22
BR0317480A (pt) 2005-11-16
AU2003294830B2 (en) 2009-06-11

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