KR100743852B1 - 4-메틸에르고스트-7-엔-3-올 골격을 갖는 글리코사이드 및고혈당 개선제 - Google Patents
4-메틸에르고스트-7-엔-3-올 골격을 갖는 글리코사이드 및고혈당 개선제 Download PDFInfo
- Publication number
- KR100743852B1 KR100743852B1 KR1020067001515A KR20067001515A KR100743852B1 KR 100743852 B1 KR100743852 B1 KR 100743852B1 KR 1020067001515 A KR1020067001515 A KR 1020067001515A KR 20067001515 A KR20067001515 A KR 20067001515A KR 100743852 B1 KR100743852 B1 KR 100743852B1
- Authority
- KR
- South Korea
- Prior art keywords
- compound
- present
- methylergost
- extract
- aloe
- Prior art date
Links
- 0 CC(C)C(C)CCC(*)C(CC1)C2(C)C1C1=CCC(C(C)C(CC3)OC(C(C4*=C)O)OC(CO)C4O)C3(C)C1CC2 Chemical compound CC(C)C(C)CCC(*)C(CC1)C2(C)C1C1=CCC(C(C)C(CC3)OC(C(C4*=C)O)OC(CO)C4O)C3(C)C1CC2 0.000 description 1
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J17/005—Glycosides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Botany (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Medical Informatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Food Science & Technology (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nutrition Science (AREA)
- Polymers & Plastics (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Steroid Compounds (AREA)
Abstract
Description
Claims (16)
- 제1항에 따르는 화합물을 건조 질량으로 O.OO1질량% 이상 함유하는 백합과 식물의 추출물 또는 이의 분획물.
- 삭제
- 제2항에 있어서, 백합과 식물이 알로에베라(Aloe barbadensis Miller)인 백합과 식물의 추출물 또는 이의 분획물.
- 제1항에 따르는 화합물을 함유하는 고혈당 개선제.
- 제2항 또는 제4항에 따르는 추출물을 함유하는 고혈당 개선제.
- 제1항에 따르는 화합물을 건조 질량으로 0.0001% 이상 함유하는 음식물.
- 제2항 또는 제4항에 따르는 추출물을 건조 질량으로 0.1% 이상 함유하는 음식물.
- 제1항에 따르는 화합물을 함유하는 백합과 식물, 이의 일부, 또는 이들의 파쇄물로부터, 동화합물을 함유하는 분획을 유기용매 또는 열수를 사용하여 추출하고 농축시킴을 포함하여, 제1항에 따르는 화합물 또는 동화합물을 함유하는 추출물을 제조하는 방법.
- 제9항에 있어서, 백합과 식물이 알로에베라인 방법.
- 삭제
- 삭제
- 삭제
- 삭제
- 삭제
- 삭제
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JPJP-P-2004-00103684 | 2004-03-31 | ||
JP2004103684 | 2004-03-31 | ||
JP2004112108 | 2004-04-06 | ||
JPJP-P-2004-00112108 | 2004-04-06 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR20060052860A KR20060052860A (ko) | 2006-05-19 |
KR100743852B1 true KR100743852B1 (ko) | 2007-08-02 |
Family
ID=35063719
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020067001515A KR100743852B1 (ko) | 2004-03-31 | 2005-03-30 | 4-메틸에르고스트-7-엔-3-올 골격을 갖는 글리코사이드 및고혈당 개선제 |
Country Status (7)
Country | Link |
---|---|
US (2) | US7534770B2 (ko) |
EP (1) | EP1731527B1 (ko) |
JP (1) | JP3883563B2 (ko) |
KR (1) | KR100743852B1 (ko) |
CA (1) | CA2533784C (ko) |
RU (1) | RU2315770C1 (ko) |
WO (1) | WO2005095436A1 (ko) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4065016B2 (ja) | 2005-05-17 | 2008-03-19 | 森永乳業株式会社 | 膵臓機能改善のための医薬又は飲食品 |
JP4162703B2 (ja) * | 2005-09-22 | 2008-10-08 | 森永乳業株式会社 | 内臓脂肪蓄積抑制剤 |
EP1930341B1 (en) | 2005-09-30 | 2016-04-27 | Morinaga Milk Industry Co., Ltd. | Agent for amelioration of insulin resistance |
WO2007043302A1 (ja) | 2005-09-30 | 2007-04-19 | Morinaga Milk Industry Co., Ltd. | インスリン抵抗性改善剤 |
KR100999317B1 (ko) | 2005-09-30 | 2010-12-09 | 모리나가 뉴교 가부시키가이샤 | 인슐린 저항성 개선제 |
CN102216317B (zh) * | 2008-11-19 | 2015-07-22 | 森永乳业株式会社 | 抗氧化剂 |
US8486899B2 (en) | 2008-11-19 | 2013-07-16 | Morinaga Milk Industry Co., Ltd. | Antioxidant |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0861595A1 (en) * | 1995-09-05 | 1998-09-02 | Kowa Chemical Industries Co., Ltd. | Gymnema inodorum roasted tea and method for preparing the same |
WO2003059360A1 (en) * | 2002-01-11 | 2003-07-24 | Medical Isotopes, Inc. | Novel cholesterol absorption lowering agents |
JP2003286185A (ja) * | 2002-03-29 | 2003-10-07 | Daily Foods Kk | アロエベラ圧搾液及び該圧搾液を有効成分とする血糖値降下剤 |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60214741A (ja) | 1984-04-05 | 1985-10-28 | Toyo Yakushiyoku Kogyo Kk | 血糖降下剤 |
JPH01312978A (ja) | 1988-06-13 | 1989-12-18 | Shiro Kobayashi | 飲料用及び添加用食品 |
JPH05247086A (ja) | 1992-01-31 | 1993-09-24 | Kowa Kagaku Kogyo Kk | 1−〔3β−(16β,28−ジヒドロキシオレアン−12−エン)オキシ〕−2−O−β−D−グルコース−β−D−グルクロン酸及びその製造方法 |
JPH06319498A (ja) * | 1993-05-12 | 1994-11-22 | Hirata Nouen:Kk | アロエジュース飲料の製造方法 |
JP3685833B2 (ja) | 1995-02-06 | 2005-08-24 | 日本メナード化粧品株式会社 | 免疫抑制改善剤 |
JP3828953B2 (ja) | 1995-05-24 | 2006-10-04 | 日本製粉株式会社 | リパーゼ阻害剤 |
JP3752000B2 (ja) | 1995-08-21 | 2006-03-08 | ユリカ株式会社 | アロエ葉皮由来のレクチン活性蛋白質 |
CA2236171A1 (en) | 1995-10-31 | 1997-05-09 | Merck & Co., Inc. | Triterpene derivatives with immunosuppressant activity |
JP3605924B2 (ja) | 1996-02-20 | 2004-12-22 | 三菱化学株式会社 | 食品の臭気マスキング剤および該マスキング剤を用いた食品の臭気マスキング方法 |
JP3966922B2 (ja) | 1996-07-18 | 2007-08-29 | 一丸ファルコス株式会社 | 線維芽細胞増殖促進剤 |
JPH1036271A (ja) | 1996-07-25 | 1998-02-10 | Kureha Chem Ind Co Ltd | Hsp27ファミリーに属するタンパク質のアロイン誘導体含有合成抑制剤 |
JPH1045604A (ja) | 1996-07-30 | 1998-02-17 | Kureha Chem Ind Co Ltd | アロイン誘導体含有hsp47合成抑制剤 |
JPH10120576A (ja) | 1996-10-16 | 1998-05-12 | Kureha Chem Ind Co Ltd | Hsp60ファミリーに属するタンパク質のアロイン誘導体含有合成抑制剤 |
JPH10330266A (ja) | 1997-06-02 | 1998-12-15 | Kotarou Kanpo Seiyaku Kk | インスリン作用増強活性組成物 |
KR100729887B1 (ko) | 1997-10-10 | 2007-06-18 | 유니젠 파아마슈티컬스,인크. | 알로에로부터 유래된 다당류를 포함하는 조성물 |
US6506387B1 (en) * | 1999-04-28 | 2003-01-14 | Paxa N.V. | Method for preparing aloin by extraction |
JP4393717B2 (ja) | 2001-01-04 | 2010-01-06 | 株式会社ユース・テクノコーポレーション | 代謝異常改善方法およびそのための組成物 |
JP2002371003A (ja) | 2001-06-15 | 2002-12-26 | Kikkoman Corp | 血糖値上昇抑制剤 |
JP3790686B2 (ja) | 2001-08-03 | 2006-06-28 | 独立行政法人理化学研究所 | 血糖降下剤 |
JP2003095941A (ja) | 2001-09-26 | 2003-04-03 | Ito En Ltd | 糖質消化酵素阻害剤、血糖値上昇抑制剤、肥満治療予防剤、糖尿病治療予防剤、健康飲食物 |
JP3879559B2 (ja) * | 2002-03-27 | 2007-02-14 | ソニー株式会社 | ステレオマイクロホン装置 |
US6884783B2 (en) | 2002-05-03 | 2005-04-26 | Unigen Pharmaceuticals, Inc. | 7-Hydroxy chromones as potent antioxidants |
-
2005
- 2005-03-30 US US10/564,464 patent/US7534770B2/en active Active
- 2005-03-30 WO PCT/JP2005/006019 patent/WO2005095436A1/ja not_active Application Discontinuation
- 2005-03-30 EP EP05727327A patent/EP1731527B1/en active Active
- 2005-03-30 RU RU2006108792/04A patent/RU2315770C1/ru not_active IP Right Cessation
- 2005-03-30 CA CA002533784A patent/CA2533784C/en active Active
- 2005-03-30 KR KR1020067001515A patent/KR100743852B1/ko active IP Right Grant
- 2005-03-30 JP JP2005518606A patent/JP3883563B2/ja active Active
-
2008
- 2008-07-25 US US12/180,241 patent/US8486462B2/en active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0861595A1 (en) * | 1995-09-05 | 1998-09-02 | Kowa Chemical Industries Co., Ltd. | Gymnema inodorum roasted tea and method for preparing the same |
WO2003059360A1 (en) * | 2002-01-11 | 2003-07-24 | Medical Isotopes, Inc. | Novel cholesterol absorption lowering agents |
JP2003286185A (ja) * | 2002-03-29 | 2003-10-07 | Daily Foods Kk | アロエベラ圧搾液及び該圧搾液を有効成分とする血糖値降下剤 |
Also Published As
Publication number | Publication date |
---|---|
RU2315770C1 (ru) | 2008-01-27 |
EP1731527B1 (en) | 2012-10-10 |
CA2533784C (en) | 2009-09-15 |
US8486462B2 (en) | 2013-07-16 |
KR20060052860A (ko) | 2006-05-19 |
US7534770B2 (en) | 2009-05-19 |
EP1731527A1 (en) | 2006-12-13 |
US20090075913A1 (en) | 2009-03-19 |
JPWO2005095436A1 (ja) | 2007-08-16 |
EP1731527A4 (en) | 2009-07-22 |
RU2006108792A (ru) | 2007-09-27 |
CA2533784A1 (en) | 2005-10-13 |
JP3883563B2 (ja) | 2007-02-21 |
WO2005095436A1 (ja) | 2005-10-13 |
US20080044500A1 (en) | 2008-02-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
KR100773261B1 (ko) | 고혈당 개선용 의약 | |
KR100843508B1 (ko) | 고혈당 개선용 의약 | |
KR100743852B1 (ko) | 4-메틸에르고스트-7-엔-3-올 골격을 갖는 글리코사이드 및고혈당 개선제 | |
JP4065016B2 (ja) | 膵臓機能改善のための医薬又は飲食品 | |
KR100941016B1 (ko) | 인슐린 저항성 개선제 | |
KR100941015B1 (ko) | 내장 지방 축적 억제제 | |
RU2315601C1 (ru) | Лекарственное средство и пищевой продукт или напиток для снижения гипергликемии |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A201 | Request for examination | ||
E902 | Notification of reason for refusal | ||
E701 | Decision to grant or registration of patent right | ||
GRNT | Written decision to grant | ||
FPAY | Annual fee payment |
Payment date: 20130611 Year of fee payment: 7 |
|
FPAY | Annual fee payment |
Payment date: 20140605 Year of fee payment: 8 |
|
FPAY | Annual fee payment |
Payment date: 20150604 Year of fee payment: 9 |
|
FPAY | Annual fee payment |
Payment date: 20160608 Year of fee payment: 10 |
|
FPAY | Annual fee payment |
Payment date: 20170612 Year of fee payment: 11 |
|
FPAY | Annual fee payment |
Payment date: 20180612 Year of fee payment: 12 |