JP3883563B2 - 4−メチルエルゴスト−7−エン−3−オール骨格を有する配糖体及び高血糖改善剤 - Google Patents

4−メチルエルゴスト−7−エン−3−オール骨格を有する配糖体及び高血糖改善剤 Download PDF

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JP3883563B2
JP3883563B2 JP2005518606A JP2005518606A JP3883563B2 JP 3883563 B2 JP3883563 B2 JP 3883563B2 JP 2005518606 A JP2005518606 A JP 2005518606A JP 2005518606 A JP2005518606 A JP 2005518606A JP 3883563 B2 JP3883563 B2 JP 3883563B2
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compound
present
composition
methylergost
mass
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JPWO2005095436A1 (ja
Inventor
隆一 樋口
昌宣 稲垣
宏紀 早澤
宗夫 山田
美順 田中
江里子 三澤
式子 脇元
洋介 伊藤
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Morinaga Milk Industry Co Ltd
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Morinaga Milk Industry Co Ltd
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J17/00Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J17/00Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J17/005Glycosides
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/886Aloeaceae (Aloe family), e.g. aloe vera
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Steroid Compounds (AREA)
JP2005518606A 2004-03-31 2005-03-30 4−メチルエルゴスト−7−エン−3−オール骨格を有する配糖体及び高血糖改善剤 Active JP3883563B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2004103684 2004-03-31
JP2004103684 2004-03-31
JP2004112108 2004-04-06
JP2004112108 2004-04-06
PCT/JP2005/006019 WO2005095436A1 (ja) 2004-03-31 2005-03-30 4-メチルエルゴスト-7-エン-3-オール骨格を有する配糖体及び高血糖改善剤

Publications (2)

Publication Number Publication Date
JP3883563B2 true JP3883563B2 (ja) 2007-02-21
JPWO2005095436A1 JPWO2005095436A1 (ja) 2007-08-16

Family

ID=35063719

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2005518606A Active JP3883563B2 (ja) 2004-03-31 2005-03-30 4−メチルエルゴスト−7−エン−3−オール骨格を有する配糖体及び高血糖改善剤

Country Status (7)

Country Link
US (2) US7534770B2 (ko)
EP (1) EP1731527B1 (ko)
JP (1) JP3883563B2 (ko)
KR (1) KR100743852B1 (ko)
CA (1) CA2533784C (ko)
RU (1) RU2315770C1 (ko)
WO (1) WO2005095436A1 (ko)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4065016B2 (ja) 2005-05-17 2008-03-19 森永乳業株式会社 膵臓機能改善のための医薬又は飲食品
JP4162703B2 (ja) * 2005-09-22 2008-10-08 森永乳業株式会社 内臓脂肪蓄積抑制剤
EP1930341B1 (en) 2005-09-30 2016-04-27 Morinaga Milk Industry Co., Ltd. Agent for amelioration of insulin resistance
WO2007043302A1 (ja) 2005-09-30 2007-04-19 Morinaga Milk Industry Co., Ltd. インスリン抵抗性改善剤
KR100999317B1 (ko) 2005-09-30 2010-12-09 모리나가 뉴교 가부시키가이샤 인슐린 저항성 개선제
CN102216317B (zh) * 2008-11-19 2015-07-22 森永乳业株式会社 抗氧化剂
US8486899B2 (en) 2008-11-19 2013-07-16 Morinaga Milk Industry Co., Ltd. Antioxidant

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60214741A (ja) 1984-04-05 1985-10-28 Toyo Yakushiyoku Kogyo Kk 血糖降下剤
JPH01312978A (ja) 1988-06-13 1989-12-18 Shiro Kobayashi 飲料用及び添加用食品
JPH05247086A (ja) 1992-01-31 1993-09-24 Kowa Kagaku Kogyo Kk 1−〔3β−(16β,28−ジヒドロキシオレアン−12−エン)オキシ〕−2−O−β−D−グルコース−β−D−グルクロン酸及びその製造方法
JPH06319498A (ja) * 1993-05-12 1994-11-22 Hirata Nouen:Kk アロエジュース飲料の製造方法
JP3685833B2 (ja) 1995-02-06 2005-08-24 日本メナード化粧品株式会社 免疫抑制改善剤
JP3828953B2 (ja) 1995-05-24 2006-10-04 日本製粉株式会社 リパーゼ阻害剤
JP3752000B2 (ja) 1995-08-21 2006-03-08 ユリカ株式会社 アロエ葉皮由来のレクチン活性蛋白質
JP2880434B2 (ja) * 1995-09-05 1999-04-12 恒和化学工業株式会社 ギムネマ・イノドラム焙煎茶
CA2236171A1 (en) 1995-10-31 1997-05-09 Merck & Co., Inc. Triterpene derivatives with immunosuppressant activity
JP3605924B2 (ja) 1996-02-20 2004-12-22 三菱化学株式会社 食品の臭気マスキング剤および該マスキング剤を用いた食品の臭気マスキング方法
JP3966922B2 (ja) 1996-07-18 2007-08-29 一丸ファルコス株式会社 線維芽細胞増殖促進剤
JPH1036271A (ja) 1996-07-25 1998-02-10 Kureha Chem Ind Co Ltd Hsp27ファミリーに属するタンパク質のアロイン誘導体含有合成抑制剤
JPH1045604A (ja) 1996-07-30 1998-02-17 Kureha Chem Ind Co Ltd アロイン誘導体含有hsp47合成抑制剤
JPH10120576A (ja) 1996-10-16 1998-05-12 Kureha Chem Ind Co Ltd Hsp60ファミリーに属するタンパク質のアロイン誘導体含有合成抑制剤
JPH10330266A (ja) 1997-06-02 1998-12-15 Kotarou Kanpo Seiyaku Kk インスリン作用増強活性組成物
KR100729887B1 (ko) 1997-10-10 2007-06-18 유니젠 파아마슈티컬스,인크. 알로에로부터 유래된 다당류를 포함하는 조성물
US6506387B1 (en) * 1999-04-28 2003-01-14 Paxa N.V. Method for preparing aloin by extraction
JP4393717B2 (ja) 2001-01-04 2010-01-06 株式会社ユース・テクノコーポレーション 代謝異常改善方法およびそのための組成物
JP2002371003A (ja) 2001-06-15 2002-12-26 Kikkoman Corp 血糖値上昇抑制剤
JP3790686B2 (ja) 2001-08-03 2006-06-28 独立行政法人理化学研究所 血糖降下剤
JP2003095941A (ja) 2001-09-26 2003-04-03 Ito En Ltd 糖質消化酵素阻害剤、血糖値上昇抑制剤、肥満治療予防剤、糖尿病治療予防剤、健康飲食物
AU2003205100A1 (en) * 2002-01-11 2003-07-30 Medical Isotopes, Inc. Novel cholesterol absorption lowering agents
JP3879559B2 (ja) * 2002-03-27 2007-02-14 ソニー株式会社 ステレオマイクロホン装置
JP2003286185A (ja) 2002-03-29 2003-10-07 Daily Foods Kk アロエベラ圧搾液及び該圧搾液を有効成分とする血糖値降下剤
US6884783B2 (en) 2002-05-03 2005-04-26 Unigen Pharmaceuticals, Inc. 7-Hydroxy chromones as potent antioxidants

Also Published As

Publication number Publication date
RU2315770C1 (ru) 2008-01-27
KR100743852B1 (ko) 2007-08-02
EP1731527B1 (en) 2012-10-10
CA2533784C (en) 2009-09-15
US8486462B2 (en) 2013-07-16
KR20060052860A (ko) 2006-05-19
US7534770B2 (en) 2009-05-19
EP1731527A1 (en) 2006-12-13
US20090075913A1 (en) 2009-03-19
JPWO2005095436A1 (ja) 2007-08-16
EP1731527A4 (en) 2009-07-22
RU2006108792A (ru) 2007-09-27
CA2533784A1 (en) 2005-10-13
WO2005095436A1 (ja) 2005-10-13
US20080044500A1 (en) 2008-02-21

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JP3905913B2 (ja) 高血糖改善のための医薬及び飲食品
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JP3883563B2 (ja) 4−メチルエルゴスト−7−エン−3−オール骨格を有する配糖体及び高血糖改善剤
JP4065016B2 (ja) 膵臓機能改善のための医薬又は飲食品
JP4169777B2 (ja) インスリン抵抗性改善剤
JP4162703B2 (ja) 内臓脂肪蓄積抑制剤

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