KR100671367B1 - 미코페놀산 또는 미코페놀레이트 염을 포함하는 제약조성물 - Google Patents

미코페놀산 또는 미코페놀레이트 염을 포함하는 제약조성물 Download PDF

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Publication number
KR100671367B1
KR100671367B1 KR1020047005588A KR20047005588A KR100671367B1 KR 100671367 B1 KR100671367 B1 KR 100671367B1 KR 1020047005588 A KR1020047005588 A KR 1020047005588A KR 20047005588 A KR20047005588 A KR 20047005588A KR 100671367 B1 KR100671367 B1 KR 100671367B1
Authority
KR
South Korea
Prior art keywords
solid dosage
mycophenolate
mycophenolic acid
tablets
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020047005588A
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English (en)
Korean (ko)
Other versions
KR20050037409A (ko
Inventor
위르겐 데데릭스
토마스 리가시
Original Assignee
노파르티스 아게
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9924043&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR100671367(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 노파르티스 아게 filed Critical 노파르티스 아게
Publication of KR20050037409A publication Critical patent/KR20050037409A/ko
Application granted granted Critical
Publication of KR100671367B1 publication Critical patent/KR100671367B1/ko
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Furan Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1020047005588A 2001-10-17 2002-10-16 미코페놀산 또는 미코페놀레이트 염을 포함하는 제약조성물 Ceased KR100671367B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0124953.1 2001-10-17
GBGB0124953.1A GB0124953D0 (en) 2001-10-17 2001-10-17 Organic Compounds

Publications (2)

Publication Number Publication Date
KR20050037409A KR20050037409A (ko) 2005-04-21
KR100671367B1 true KR100671367B1 (ko) 2007-01-19

Family

ID=9924043

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020047005588A Ceased KR100671367B1 (ko) 2001-10-17 2002-10-16 미코페놀산 또는 미코페놀레이트 염을 포함하는 제약조성물

Country Status (31)

Country Link
US (3) US20050013859A1 (enExample)
EP (1) EP1438040B2 (enExample)
JP (2) JP2005508959A (enExample)
KR (1) KR100671367B1 (enExample)
CN (1) CN1310640C (enExample)
AR (2) AR036813A1 (enExample)
AT (1) ATE374023T1 (enExample)
AU (1) AU2002338897B2 (enExample)
BR (1) BR0213355A (enExample)
CA (1) CA2460574A1 (enExample)
CO (1) CO5390076A1 (enExample)
CY (1) CY1107841T1 (enExample)
DE (1) DE60222687T3 (enExample)
DK (1) DK1438040T4 (enExample)
EC (2) ECSP024342A (enExample)
ES (1) ES2292819T5 (enExample)
GB (1) GB0124953D0 (enExample)
HU (1) HU231114B1 (enExample)
IL (2) IL160968A0 (enExample)
MX (1) MXPA04003636A (enExample)
MY (1) MY139206A (enExample)
NO (1) NO341804B1 (enExample)
NZ (1) NZ532280A (enExample)
PE (1) PE20030476A1 (enExample)
PL (2) PL234541B1 (enExample)
PT (1) PT1438040E (enExample)
RU (2) RU2338528C2 (enExample)
SI (1) SI1438040T2 (enExample)
TW (1) TWI333861B (enExample)
WO (1) WO2003032978A1 (enExample)
ZA (1) ZA200401977B (enExample)

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GB0419355D0 (en) * 2004-08-31 2004-09-29 Novartis Ag Organic compounds
WO2006086498A2 (en) * 2005-02-08 2006-08-17 Aspreva Pharmaceuticals Sa Treatment of vascular, autoimmune and inflammatory diseases using low dosages of impdh inhibitors
WO2006086500A2 (en) * 2005-02-08 2006-08-17 Aspreva Pharmaceuticals Sa Compositions and methods for treating vascular, autoimmune and inflammatory diseases
EP1940388A2 (en) * 2005-09-30 2008-07-09 Novartis AG Dpp iv inhibtor for use in the treatment of autoimmune diseases and graft rejection
EP1965760B1 (de) 2005-12-21 2013-02-27 Basf Se Feinteiliges quervernetztes polyvinylpyrrolidon als tablettensprengmittel
CA2640283A1 (en) * 2006-02-13 2007-08-23 Novartis Ag High dosage of mycophenolic acid (mpa)
WO2008148742A2 (de) 2007-06-06 2008-12-11 Basf Se Pharmazeutische formulierung für die herstellung von schnell zerfallenden tabletten
US8568780B2 (en) 2007-06-06 2013-10-29 Basf Se Pharmaceutical formulation for the production of rapidly disintegrating tablets
MX2010001711A (es) * 2007-08-13 2010-03-11 Panacea Biotec Ltd Composiciones de liberacion extendida que comprenden micofenolato sodico y procedimientos de las mismas.
AU2009220779A1 (en) * 2008-03-05 2009-09-11 Panacea Biotec Limited Modified release pharmaceutical compositions comprising mycophenolate and processes thereof
US20100010082A1 (en) * 2008-07-09 2010-01-14 Aspreva International Ltd. Formulations for treating eye disorders
US20110086102A1 (en) * 2009-10-13 2011-04-14 Teva Pharmaceutical Industries Ltd. Delayed release compositions
WO2011046546A1 (en) * 2009-10-13 2011-04-21 Teva Pharmaceutical Industries Ltd. Delayed release compositions
WO2011051967A2 (en) * 2009-10-23 2011-05-05 Alkem Laboratories Ltd Pharmaceutical compositions comprising mycophenolate and processes for preparing thereof
GB201100786D0 (en) 2011-01-18 2011-03-02 Ems Sa Pharmaceutical compositions of immunosuppressants
CN102793658A (zh) * 2012-08-23 2012-11-28 无锡福祈制药有限公司 一种含有麦考酚酸或麦考酚酸盐的骨架型制剂及其包衣片
CN103845323B (zh) * 2012-11-30 2018-02-02 重庆华邦制药有限公司 麦考酚酸及其盐肠溶制剂和制备方法
WO2014167442A1 (en) 2013-03-26 2014-10-16 Wockhardt Limited Pharmaceutical compositions comprising mycophenolic acid or salts thereof
CN106727403A (zh) * 2017-01-03 2017-05-31 无锡福祈制药有限公司 一种麦考酚钠肠溶片及其制备方法
JP7385474B2 (ja) * 2017-03-13 2023-11-22 オカヴァ ファーマシューティカルズ， インコーポレイテッド 非ヒト哺乳動物にミコフェノール酸活性剤を送達すための方法および組成物
CA3102412A1 (en) 2018-06-06 2019-12-12 Metavant Sciences Gmbh Methods of treating subjects having diabetes with chronic kidney disease
WO2019238647A1 (en) * 2018-06-14 2019-12-19 Poxel Film-coated tablet comprising a triazine derivative for use in the treatment of diabetes
RU2723255C2 (ru) * 2018-11-14 2020-06-09 Общество с ограниченной ответственностью "Изварино Фарма" Экструдат с микофенолятом натрия для получения пероральной твердой лекарственной формы
EP4438037A1 (en) * 2021-01-28 2024-10-02 Priothera SAS Methods of treatment with s1p receptor modulators
EP4346790A4 (en) * 2021-05-26 2025-04-16 The Texas A&M University System Biodegradable mucoadhesive pharmaceutical formulations and methods thereof
CN117442580B (zh) * 2023-12-21 2024-04-05 泊诺(天津)创新医药研究有限公司 一种高生物利用度麦考酚钠肠溶片及其制备方法

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Also Published As

Publication number Publication date
US20050013859A1 (en) 2005-01-20
DE60222687T3 (de) 2020-03-05
TWI333861B (en) 2010-12-01
US20120237601A1 (en) 2012-09-20
ECSP024341A (es) 2003-12-01
ZA200401977B (en) 2006-05-31
MXPA04003636A (es) 2004-07-27
ATE374023T1 (de) 2007-10-15
BR0213355A (pt) 2006-05-23
KR20050037409A (ko) 2005-04-21
NO341804B1 (no) 2018-01-22
CN1564684A (zh) 2005-01-12
IL160968A0 (en) 2004-08-31
AU2002338897B2 (en) 2006-10-19
SI1438040T2 (sl) 2020-02-28
GB0124953D0 (en) 2001-12-05
EP1438040B1 (en) 2007-09-26
PT1438040E (pt) 2008-01-02
MY139206A (en) 2009-08-28
PL415001A1 (pl) 2016-02-29
RU2007130786A (ru) 2009-02-20
PL367738A1 (en) 2005-03-07
DK1438040T4 (da) 2020-01-27
PL234541B1 (pl) 2020-03-31
SI1438040T1 (sl) 2008-04-30
JP2009137996A (ja) 2009-06-25
EP1438040B2 (en) 2019-10-16
NO20041785L (no) 2004-05-03
DE60222687T2 (de) 2008-07-17
US20100210717A1 (en) 2010-08-19
ES2292819T3 (es) 2008-03-16
CY1107841T1 (el) 2013-06-19
HU231114B1 (hu) 2020-09-28
EP1438040A1 (en) 2004-07-21
CO5390076A1 (es) 2004-04-30
JP2005508959A (ja) 2005-04-07
HUP0600451A2 (en) 2006-09-28
IL160968A (en) 2016-04-21
DE60222687D1 (de) 2007-11-08
DK1438040T3 (da) 2008-02-04
PE20030476A1 (es) 2003-07-30
RU2381026C2 (ru) 2010-02-10
AR085778A2 (es) 2013-10-30
HK1067861A1 (en) 2005-04-22
ES2292819T5 (es) 2020-05-29
CN1310640C (zh) 2007-04-18
CA2460574A1 (en) 2003-04-24
NZ532280A (en) 2007-05-31
AR036813A1 (es) 2004-10-06
RU2338528C2 (ru) 2008-11-20
WO2003032978A1 (en) 2003-04-24
ECSP024342A (es) 2003-03-10
RU2004115332A (ru) 2005-04-20

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