CA2460574A1 - Enteric coated tablets comprising mycophenolic acid or mycophenolate salt - Google Patents
Enteric coated tablets comprising mycophenolic acid or mycophenolate salt Download PDFInfo
- Publication number
- CA2460574A1 CA2460574A1 CA002460574A CA2460574A CA2460574A1 CA 2460574 A1 CA2460574 A1 CA 2460574A1 CA 002460574 A CA002460574 A CA 002460574A CA 2460574 A CA2460574 A CA 2460574A CA 2460574 A1 CA2460574 A1 CA 2460574A1
- Authority
- CA
- Canada
- Prior art keywords
- tablet
- mycophenolate
- salt
- mycophenolic acid
- solid dosage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- HPNSFSBZBAHARI-RUDMXATFSA-N mycophenolic acid Chemical compound OC1=C(C\C=C(/C)CCC(O)=O)C(OC)=C(C)C2=C1C(=O)OC2 HPNSFSBZBAHARI-RUDMXATFSA-N 0.000 title claims abstract description 89
- HPNSFSBZBAHARI-UHFFFAOYSA-N micophenolic acid Natural products OC1=C(CC=C(C)CCC(O)=O)C(OC)=C(C)C2=C1C(=O)OC2 HPNSFSBZBAHARI-UHFFFAOYSA-N 0.000 title claims abstract description 59
- 229960000951 mycophenolic acid Drugs 0.000 title claims abstract description 36
- 239000002662 enteric coated tablet Substances 0.000 title description 3
- 238000000034 method Methods 0.000 claims abstract description 38
- 239000007909 solid dosage form Substances 0.000 claims abstract description 15
- 230000008569 process Effects 0.000 claims abstract description 14
- 239000000203 mixture Substances 0.000 claims description 36
- 239000000654 additive Substances 0.000 claims description 26
- 238000009505 enteric coating Methods 0.000 claims description 14
- 239000002702 enteric coating Substances 0.000 claims description 14
- 238000007906 compression Methods 0.000 claims description 12
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- 239000008187 granular material Substances 0.000 claims description 10
- 230000001506 immunosuppresive effect Effects 0.000 claims description 10
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- KEAYESYHFKHZAL-UHFFFAOYSA-N Sodium Chemical class [Na] KEAYESYHFKHZAL-UHFFFAOYSA-N 0.000 claims description 3
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Landscapes
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| CA002460574A Abandoned CA2460574A1 (en) | 2001-10-17 | 2002-10-16 | Enteric coated tablets comprising mycophenolic acid or mycophenolate salt |
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| AR045957A1 (es) * | 2003-10-03 | 2005-11-16 | Novartis Ag | Composicion farmaceutica y combinacion |
| CN101052631A (zh) * | 2004-07-20 | 2007-10-10 | 特瓦药厂私人有限公司 | 结晶霉酚酸钠 |
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| WO2006086498A2 (en) * | 2005-02-08 | 2006-08-17 | Aspreva Pharmaceuticals Sa | Treatment of vascular, autoimmune and inflammatory diseases using low dosages of impdh inhibitors |
| WO2006086500A2 (en) * | 2005-02-08 | 2006-08-17 | Aspreva Pharmaceuticals Sa | Compositions and methods for treating vascular, autoimmune and inflammatory diseases |
| EP1940388A2 (en) * | 2005-09-30 | 2008-07-09 | Novartis AG | Dpp iv inhibtor for use in the treatment of autoimmune diseases and graft rejection |
| EP1965760B1 (de) | 2005-12-21 | 2013-02-27 | Basf Se | Feinteiliges quervernetztes polyvinylpyrrolidon als tablettensprengmittel |
| CA2640283A1 (en) * | 2006-02-13 | 2007-08-23 | Novartis Ag | High dosage of mycophenolic acid (mpa) |
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