KR100633348B1 - 메틸페니데이트를 이용하여 주의력 결핍 장애 및 주의력 결핍/과잉행동 장애를 치료하기 위한 조성물 및 방법 - Google Patents
메틸페니데이트를 이용하여 주의력 결핍 장애 및 주의력 결핍/과잉행동 장애를 치료하기 위한 조성물 및 방법 Download PDFInfo
- Publication number
- KR100633348B1 KR100633348B1 KR1020007006477A KR20007006477A KR100633348B1 KR 100633348 B1 KR100633348 B1 KR 100633348B1 KR 1020007006477 A KR1020007006477 A KR 1020007006477A KR 20007006477 A KR20007006477 A KR 20007006477A KR 100633348 B1 KR100633348 B1 KR 100633348B1
- Authority
- KR
- South Korea
- Prior art keywords
- methylphenidate
- composition
- amount
- present
- hours
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4458—Non condensed piperidines, e.g. piperocaine only substituted in position 2, e.g. methylphenidate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6951097P | 1997-12-15 | 1997-12-15 | |
| US60/069,510 | 1998-09-30 | ||
| US9/163,351 | 1998-09-30 | ||
| US09/163,351 | 1998-09-30 | ||
| US09/163,351 US6210705B1 (en) | 1997-12-15 | 1998-09-30 | Compositions and methods for treatment of attention deficit disorder and attention deficit/hyperactivity disorder with methylphenidate |
| PCT/US1998/026560 WO1999030694A2 (en) | 1997-12-15 | 1998-12-14 | Compositions and methods for treatment of attention deficit disorder and attention deficit/hyperactivity disorder with methylphenidate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20010033114A KR20010033114A (ko) | 2001-04-25 |
| KR100633348B1 true KR100633348B1 (ko) | 2006-10-16 |
Family
ID=26750154
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020007006477A Expired - Fee Related KR100633348B1 (ko) | 1997-12-15 | 1998-12-14 | 메틸페니데이트를 이용하여 주의력 결핍 장애 및 주의력 결핍/과잉행동 장애를 치료하기 위한 조성물 및 방법 |
Country Status (28)
| Country | Link |
|---|---|
| US (2) | US6210705B1 (https=) |
| EP (2) | EP2314288B1 (https=) |
| JP (3) | JP4316800B2 (https=) |
| KR (1) | KR100633348B1 (https=) |
| CN (1) | CN1368876A (https=) |
| AR (1) | AR014062A1 (https=) |
| AT (1) | ATE260652T1 (https=) |
| AU (1) | AU752027B2 (https=) |
| BR (1) | BR9814282A (https=) |
| CA (1) | CA2315237C (https=) |
| CZ (2) | CZ300535B6 (https=) |
| DE (1) | DE69822199T2 (https=) |
| DK (1) | DK1037615T3 (https=) |
| ES (2) | ES2219926T3 (https=) |
| HK (1) | HK1049447A1 (https=) |
| HU (1) | HU226615B1 (https=) |
| IL (1) | IL136760A0 (https=) |
| LV (1) | LV12558B (https=) |
| NO (1) | NO329974B1 (https=) |
| NZ (1) | NZ505689A (https=) |
| PE (1) | PE20000120A1 (https=) |
| PL (1) | PL195315B1 (https=) |
| PT (1) | PT1037615E (https=) |
| RU (1) | RU2233156C2 (https=) |
| SI (1) | SI20360B (https=) |
| TR (1) | TR200001736T2 (https=) |
| TW (2) | TWI242452B (https=) |
| WO (1) | WO1999030694A2 (https=) |
Families Citing this family (68)
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| US5968547A (en) | 1997-02-24 | 1999-10-19 | Euro-Celtique, S.A. | Method of providing sustained analgesia with buprenorphine |
| US20020102291A1 (en) * | 1997-12-15 | 2002-08-01 | Noven Pharmaceuticals, Inc. | Compositions and method for treatment of attention deficit disorder and attention deficit/hyperactivity disorder with methylphenidate |
| GB9913458D0 (en) * | 1999-06-09 | 1999-08-11 | Medeva Europ Ltd | The therapeutic use of d-threo-methylphenidate |
| GB9918735D0 (en) * | 1999-08-09 | 1999-10-13 | Straken Limited | Transdermal patches |
| CO5261532A1 (es) * | 1999-11-15 | 2003-03-31 | Novartis Ag | Compuestos heterociclicos sililados, procedimiento para la preparacion de estos y composicion farmaceutica que los contiene |
| AU2199901A (en) * | 1999-12-17 | 2001-06-25 | Medeva Europe Limited | The treatment of convulsive states |
| US6455066B1 (en) | 2000-03-10 | 2002-09-24 | Epicept Corporation | Intradermal-penetration agents for topical local anesthetic administration |
| US6905016B2 (en) * | 2000-03-14 | 2005-06-14 | Noven Pharmaceuticals, Inc. | Packaging system for transdermal drug delivery systems |
| US7674480B2 (en) * | 2000-06-23 | 2010-03-09 | Teva Pharmaceutical Industries Ltd. | Rapidly expanding composition for gastric retention and controlled release of therapeutic agents, and dosage forms including the composition |
| US20020119187A1 (en) * | 2000-09-29 | 2002-08-29 | Cantor Adam S. | Composition for the transdermal delivery of fentanyl |
| DE10060550C1 (de) * | 2000-12-06 | 2002-04-18 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System mit dem Wirkstoff Oxybutynin und Verfahren zur Herstellung Oxybutynin enthaltender Wirkstoffschichten |
| ES2559666T3 (es) * | 2001-03-07 | 2016-02-15 | Hisamitsu Pharmaceutical Co., Inc. | Parche adhesivo |
| FR2822049B1 (fr) * | 2001-03-13 | 2003-08-01 | Dbv Medica 1 | Patch destine notamment a depister l'etat de sensibilisation d'un sujet a un allergene, procede de fabrication et utilisation |
| ES2270746T3 (es) * | 2001-03-16 | 2007-12-01 | Alza Corporation | Parche transdermico para administrar fentanilo. |
| US20050208117A1 (en) * | 2001-03-16 | 2005-09-22 | Venkatraman Subramanian S | Transdermal administration of fentanyl and analogs thereof |
| DE10141650C1 (de) * | 2001-08-24 | 2002-11-28 | Lohmann Therapie Syst Lts | Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen |
| DE10141652B4 (de) * | 2001-08-24 | 2011-04-07 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System auf der Basis von Polyacrylat-Haftklebern ohne funktionelle Gruppen und seine Verwendung |
| US20030049272A1 (en) * | 2001-08-30 | 2003-03-13 | Yatindra Joshi | Pharmaceutical composition which produces irritation |
| JP4354678B2 (ja) * | 2002-08-28 | 2009-10-28 | 久光製薬株式会社 | 貼付剤 |
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| ATE482695T1 (de) | 2002-12-13 | 2010-10-15 | Durect Corp | Orale darreichungsform mit flüssigen hochviskosen trägersystemen |
| CA2542778C (en) * | 2003-10-28 | 2012-05-29 | Noven Pharmaceuticals, Inc. | Transdermal drug delivery composition |
| NZ556456A (en) | 2005-01-20 | 2010-12-24 | Inst Molecular Medicine Inc | Methylphenidate derivatives and uses of them |
| HRP20110779T1 (hr) * | 2005-01-20 | 2011-12-31 | Institute For Molecular Medicine | Upotrebe derivata metilfenidata |
| CA2633599C (en) * | 2005-12-23 | 2015-02-10 | Epinamics Gmbh | Use of film-forming hair-care polymers from the group of polyurethanes and pharmaceutical preparations and plasters containing said polymers |
| US9393218B2 (en) * | 2005-12-23 | 2016-07-19 | Epinamics Gmbh | Use of film-forming hair care polymers from the group of polyurethanes and pharmaceutical preparations and patches that contain these polymers |
| CA2643037C (en) * | 2006-02-27 | 2014-08-05 | Noven Pharmaceuticals, Inc. | Compositions and methods for delivery of amino-functional drugs |
| AU2007248284B2 (en) * | 2006-05-01 | 2011-03-17 | Colgate-Palmolive Company | Oral care composition with silicone composite |
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| FR2924350B1 (fr) * | 2007-12-03 | 2010-08-13 | Dbv Tech | Procede et compositions pour la vaccination par voie cutanee |
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| US8916588B2 (en) | 2011-03-23 | 2014-12-23 | Ironshore Pharmaceuticals & Development, Inc. | Methods for treatment of attention deficit hyperactivity disorder |
| US9603809B2 (en) | 2011-03-23 | 2017-03-28 | Ironshore Pharmaceuticals & Development, Inc. | Methods of treatment of attention deficit hyperactivity disorder |
| US9283214B2 (en) | 2011-03-23 | 2016-03-15 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
| US10292937B2 (en) | 2011-03-23 | 2019-05-21 | Ironshore Pharmaceuticals & Development, Inc. | Methods of treatment of attention deficit hyperactivity disorder |
| US10905652B2 (en) | 2011-03-23 | 2021-02-02 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
| US8927010B2 (en) | 2011-03-23 | 2015-01-06 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
| US11241391B2 (en) | 2011-03-23 | 2022-02-08 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
| US9119809B2 (en) | 2011-03-23 | 2015-09-01 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
| AU2012230733B2 (en) | 2011-03-23 | 2016-10-20 | Ironshore Pharmaceuticals & Development, Inc. | Methods and compositions for treatment of attention deficit disorder |
| US9498447B2 (en) | 2011-03-23 | 2016-11-22 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
| CA3123900A1 (en) * | 2011-07-28 | 2013-01-31 | Kempharm Inc. | Methylphenidate-prodrugs, processes of making and using the same |
| AR092999A1 (es) | 2012-10-15 | 2015-05-13 | Noven Pharma | Composiciones y metodos para la administracion transdermica de metilfenidato |
| US9265458B2 (en) | 2012-12-04 | 2016-02-23 | Sync-Think, Inc. | Application of smooth pursuit cognitive testing paradigms to clinical drug development |
| WO2014106014A1 (en) | 2012-12-28 | 2014-07-03 | Noven Pharmaceuticals, Inc | Transdermal drug delivery systems for levonorgestrel and ethinyl estradiol |
| AU2013370297A1 (en) | 2012-12-28 | 2015-07-16 | Noven Pharmaceuticals, Inc. | Multi-polymer compositions for transdermal drug delivery |
| US9380976B2 (en) | 2013-03-11 | 2016-07-05 | Sync-Think, Inc. | Optical neuroinformatics |
| US11337936B2 (en) | 2013-03-14 | 2022-05-24 | Noven Pharmaceuticals, Inc. | Amphetamine transdermal compositions with acrylic block copolymer |
| AR095259A1 (es) | 2013-03-15 | 2015-09-30 | Noven Pharma | Composiciones y métodos para la administración transdérmica de fármacos de amina terciaria |
| TW201521769A (zh) | 2013-03-15 | 2015-06-16 | Durect Corp | 具有流變改質劑以減少溶解變異性之組成物 |
| AR095260A1 (es) | 2013-03-15 | 2015-09-30 | Noven Pharma | Composiciones de anfetaminas transdérmicas estables y métodos de fabricación |
| CA2932301A1 (en) | 2013-12-25 | 2015-07-02 | Fujimoto Co., Ltd. | Prophylactic and therapeutic agent for attention-deficit/hyperactivity disorder |
| US9980921B2 (en) * | 2016-06-30 | 2018-05-29 | Taho Pharmaceuticals Ltd. | Transdermal delivery system containing methylphenidate or its salts and methods thereof |
| SG11201811760VA (en) | 2016-07-06 | 2019-01-30 | Durect Corp | Oral dosage form with drug composition, barrier layer and drug layer |
| CN106511264A (zh) * | 2016-11-15 | 2017-03-22 | 北京万全德众医药生物技术有限公司 | 一种盐酸哌甲酯口服溶液剂及其制备方法 |
| HUE067004T2 (hu) | 2016-12-11 | 2024-10-28 | Zevra Therapeutics Inc | Metilfenidát prodrogokat tartalmazó készítmények, eljárások azok elõállítására és felhasználására |
| EP3598982A1 (en) | 2018-07-23 | 2020-01-29 | Centre National De La Recherche Scientifique | Bioconjugates of neuropeptides derivatives |
| JP7600661B2 (ja) * | 2020-12-11 | 2024-12-17 | artience株式会社 | 貼付剤 |
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| US5601839A (en) * | 1995-04-26 | 1997-02-11 | Theratech, Inc. | Triacetin as a penetration enhancer for transdermal delivery of a basic drug |
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-
1998
- 1998-09-30 US US09/163,351 patent/US6210705B1/en not_active Expired - Lifetime
- 1998-12-14 TW TW087120741A patent/TWI242452B/zh not_active IP Right Cessation
- 1998-12-14 CN CN98813634A patent/CN1368876A/zh active Pending
- 1998-12-14 DK DK98963170T patent/DK1037615T3/da active
- 1998-12-14 PT PT98963170T patent/PT1037615E/pt unknown
- 1998-12-14 DE DE69822199T patent/DE69822199T2/de not_active Expired - Lifetime
- 1998-12-14 ES ES98963170T patent/ES2219926T3/es not_active Expired - Lifetime
- 1998-12-14 NZ NZ505689A patent/NZ505689A/xx not_active IP Right Cessation
- 1998-12-14 CZ CZ20002209A patent/CZ300535B6/cs not_active IP Right Cessation
- 1998-12-14 JP JP2000538677A patent/JP4316800B2/ja not_active Expired - Lifetime
- 1998-12-14 HK HK03101632.9A patent/HK1049447A1/zh unknown
- 1998-12-14 AU AU18249/99A patent/AU752027B2/en not_active Ceased
- 1998-12-14 EP EP10011358.8A patent/EP2314288B1/en not_active Expired - Lifetime
- 1998-12-14 TW TW092128573A patent/TWI244396B/zh not_active IP Right Cessation
- 1998-12-14 EP EP98963170A patent/EP1037615B1/en not_active Expired - Lifetime
- 1998-12-14 SI SI9820083A patent/SI20360B/sl not_active IP Right Cessation
- 1998-12-14 HU HU0004539A patent/HU226615B1/hu not_active IP Right Cessation
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- 1998-12-14 KR KR1020007006477A patent/KR100633348B1/ko not_active Expired - Fee Related
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- 1998-12-14 AT AT98963170T patent/ATE260652T1/de active
- 1998-12-14 BR BR9814282-8A patent/BR9814282A/pt not_active Application Discontinuation
- 1998-12-14 RU RU2000119097/15A patent/RU2233156C2/ru not_active IP Right Cessation
- 1998-12-14 WO PCT/US1998/026560 patent/WO1999030694A2/en not_active Ceased
- 1998-12-14 CZ CZ2009-132A patent/CZ305817B6/cs not_active IP Right Cessation
- 1998-12-14 CA CA002315237A patent/CA2315237C/en not_active Expired - Lifetime
- 1998-12-15 PE PE1998001219A patent/PE20000120A1/es not_active Application Discontinuation
- 1998-12-15 AR ARP980106392A patent/AR014062A1/es not_active Application Discontinuation
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2000
- 2000-06-15 NO NO20003096A patent/NO329974B1/no not_active IP Right Cessation
- 2000-07-17 LV LVP-00-92A patent/LV12558B/en unknown
- 2000-07-18 US US09/618,626 patent/US6348211B1/en not_active Expired - Lifetime
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2008
- 2008-11-13 JP JP2008291364A patent/JP2009073856A/ja active Pending
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2012
- 2012-12-26 JP JP2012282405A patent/JP2013056944A/ja active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5601839A (en) * | 1995-04-26 | 1997-02-11 | Theratech, Inc. | Triacetin as a penetration enhancer for transdermal delivery of a basic drug |
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