KR100574153B1 - 아지트로마이신의 결정형 - Google Patents

아지트로마이신의 결정형 Download PDF

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Publication number
KR100574153B1
KR100574153B1 KR1020037015125A KR20037015125A KR100574153B1 KR 100574153 B1 KR100574153 B1 KR 100574153B1 KR 1020037015125 A KR1020037015125 A KR 1020037015125A KR 20037015125 A KR20037015125 A KR 20037015125A KR 100574153 B1 KR100574153 B1 KR 100574153B1
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South Korea
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azithromycin
type
ppm
weight
peaks
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Expired - Fee Related
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Korean (ko)
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KR20040014525A (ko
Inventor
리젱제인
트라스크앤드류빈센트
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화이자 프로덕츠 인코포레이티드
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2813—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/282—Organic compounds, e.g. fats
    • A61K9/2826—Sugars or sugar alcohols, e.g. sucrose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
KR1020037015125A 2001-05-22 2002-05-01 아지트로마이신의 결정형 Expired - Fee Related KR100574153B1 (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US29256501P 2001-05-22 2001-05-22
US60/292,565 2001-05-22
US29774101P 2001-06-12 2001-06-12
US60/297,741 2001-06-12
US34304101P 2001-12-21 2001-12-21
US60/343,041 2001-12-21
PCT/IB2002/001570 WO2002094843A1 (en) 2001-05-22 2002-05-01 Crystal forms of azithromycin

Publications (2)

Publication Number Publication Date
KR20040014525A KR20040014525A (ko) 2004-02-14
KR100574153B1 true KR100574153B1 (ko) 2006-04-25

Family

ID=27404135

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020037015125A Expired - Fee Related KR100574153B1 (ko) 2001-05-22 2002-05-01 아지트로마이신의 결정형

Country Status (35)

Country Link
US (10) US6977243B2 (enExample)
EP (1) EP1390377B1 (enExample)
JP (3) JP2004530703A (enExample)
KR (1) KR100574153B1 (enExample)
AP (1) AP2003002906A0 (enExample)
AR (1) AR036022A1 (enExample)
AT (2) ATE404575T1 (enExample)
AU (1) AU2002256846B2 (enExample)
BG (1) BG108370A (enExample)
BR (1) BR0209918A (enExample)
CA (1) CA2391659C (enExample)
CR (1) CR7159A (enExample)
CZ (1) CZ20033154A3 (enExample)
DE (2) DE60228345D1 (enExample)
DK (1) DK1390377T3 (enExample)
EA (2) EA007618B1 (enExample)
EE (1) EE200300575A (enExample)
ES (2) ES2310886T3 (enExample)
GE (1) GEP20084399B (enExample)
HU (1) HUP0400446A2 (enExample)
IL (1) IL158591A0 (enExample)
IS (1) IS7007A (enExample)
MA (1) MA27023A1 (enExample)
MX (1) MXPA03010028A (enExample)
MY (1) MY129319A (enExample)
NO (2) NO321894B1 (enExample)
NZ (2) NZ529118A (enExample)
PA (1) PA8545701A1 (enExample)
PE (1) PE20021064A1 (enExample)
PL (1) PL367091A1 (enExample)
PT (1) PT1390377E (enExample)
SK (1) SK14402003A3 (enExample)
TN (1) TNSN03121A1 (enExample)
WO (1) WO2002094843A1 (enExample)
YU (1) YU91603A (enExample)

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US6861413B2 (en) * 2001-05-22 2005-03-01 Pfizer Inc. Stable non-dihydrate azithromycin oral suspensions
IL161398A0 (en) 2001-10-18 2004-09-27 Teva Pharma Stabilized azithromycin compositions

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