KR100560036B1 - 신규의 스피로아자바이시클릭 이종원자고리화합물 - Google Patents

신규의 스피로아자바이시클릭 이종원자고리화합물 Download PDF

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Publication number
KR100560036B1
KR100560036B1 KR1020007000526A KR20007000526A KR100560036B1 KR 100560036 B1 KR100560036 B1 KR 100560036B1 KR 1020007000526 A KR1020007000526 A KR 1020007000526A KR 20007000526 A KR20007000526 A KR 20007000526A KR 100560036 B1 KR100560036 B1 KR 100560036B1
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South Korea
Prior art keywords
azabicyclo
octane
furo
pyridine
alkyl
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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KR1020007000526A
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English (en)
Korean (ko)
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KR20010021961A (enExample
Inventor
에이피온 필립스
로버트 맥
존 맥커
사이몬 세머스
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아스트라제네카 악티에볼라그
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Priority claimed from SE9702746A external-priority patent/SE9702746D0/xx
Priority claimed from SE9800977A external-priority patent/SE9800977D0/xx
Application filed by 아스트라제네카 악티에볼라그 filed Critical 아스트라제네카 악티에볼라그
Publication of KR20010021961A publication Critical patent/KR20010021961A/ko
Application granted granted Critical
Publication of KR100560036B1 publication Critical patent/KR100560036B1/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KR1020007000526A 1997-07-18 1998-07-10 신규의 스피로아자바이시클릭 이종원자고리화합물 Expired - Fee Related KR100560036B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
SE9702746-0 1997-07-18
SE9702746A SE9702746D0 (sv) 1997-07-18 1997-07-18 New compounds
SE9800977-2 1998-03-24
SE9800977A SE9800977D0 (sv) 1998-03-24 1998-03-24 New compounds
PCT/SE1998/001364 WO1999003859A1 (en) 1997-07-18 1998-07-10 Novel spiroazabicyclic heterocyclic compounds

Publications (2)

Publication Number Publication Date
KR20010021961A KR20010021961A (enExample) 2001-03-15
KR100560036B1 true KR100560036B1 (ko) 2006-03-13

Family

ID=26663041

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020007000526A Expired - Fee Related KR100560036B1 (ko) 1997-07-18 1998-07-10 신규의 스피로아자바이시클릭 이종원자고리화합물

Country Status (31)

Country Link
US (6) US6110914A (enExample)
EP (2) EP1213291B1 (enExample)
JP (1) JP2001510194A (enExample)
KR (1) KR100560036B1 (enExample)
CN (1) CN1117755C (enExample)
AR (2) AR013184A1 (enExample)
AT (2) ATE225792T1 (enExample)
AU (1) AU739022B2 (enExample)
BR (1) BR9810924A (enExample)
CA (1) CA2296031C (enExample)
DE (2) DE69827977T2 (enExample)
DK (1) DK0996622T3 (enExample)
EE (1) EE04399B1 (enExample)
ES (2) ES2185185T3 (enExample)
HK (1) HK1046274B (enExample)
HU (1) HUP0003844A3 (enExample)
ID (1) ID25548A (enExample)
IL (2) IL134086A0 (enExample)
IS (2) IS2027B (enExample)
MY (1) MY116761A (enExample)
NO (1) NO325324B1 (enExample)
NZ (1) NZ502298A (enExample)
PL (1) PL193065B1 (enExample)
PT (1) PT996622E (enExample)
RU (1) RU2202553C2 (enExample)
SA (1) SA98190668B1 (enExample)
SI (1) SI0996622T1 (enExample)
SK (1) SK283484B6 (enExample)
TR (1) TR200000129T2 (enExample)
TW (1) TW515799B (enExample)
WO (1) WO1999003859A1 (enExample)

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