KR100554859B1 - 일산화질소 생산을 억제하기 위한 테트라사이클린 화합물을 포함하는 약제학적 조성물 - Google Patents
일산화질소 생산을 억제하기 위한 테트라사이클린 화합물을 포함하는 약제학적 조성물 Download PDFInfo
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- KR100554859B1 KR100554859B1 KR1019997001591A KR19997001591A KR100554859B1 KR 100554859 B1 KR100554859 B1 KR 100554859B1 KR 1019997001591 A KR1019997001591 A KR 1019997001591A KR 19997001591 A KR19997001591 A KR 19997001591A KR 100554859 B1 KR100554859 B1 KR 100554859B1
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8/697,815 | 1996-08-30 | ||
| US08/697,815 US5789395A (en) | 1996-08-30 | 1996-08-30 | Method of using tetracycline compounds for inhibition of endogenous nitric oxide production |
| US08/697,815 | 1996-08-30 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20000035881A KR20000035881A (ko) | 2000-06-26 |
| KR100554859B1 true KR100554859B1 (ko) | 2006-02-24 |
Family
ID=24802673
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019997001591A Expired - Lifetime KR100554859B1 (ko) | 1996-08-30 | 1997-08-21 | 일산화질소 생산을 억제하기 위한 테트라사이클린 화합물을 포함하는 약제학적 조성물 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US5789395A (https=) |
| EP (1) | EP0966525A4 (https=) |
| JP (1) | JP4451930B2 (https=) |
| KR (1) | KR100554859B1 (https=) |
| AU (1) | AU718234B2 (https=) |
| CA (2) | CA2670296A1 (https=) |
| NZ (1) | NZ334512A (https=) |
| WO (1) | WO1998008480A2 (https=) |
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| US5605798A (en) | 1993-01-07 | 1997-02-25 | Sequenom, Inc. | DNA diagnostic based on mass spectrometry |
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| DE69738206T2 (de) | 1996-11-06 | 2008-07-17 | Sequenom, Inc., San Diego | DNA-Diagnostik mittels Massenspektrometrie |
| DE69735445T2 (de) | 1996-12-10 | 2006-08-10 | Sequenom, Inc., San Diego | Abspaltbare, nicht-flüchtige moleküle zur massenmarkierung |
| WO1998033379A1 (en) * | 1997-02-04 | 1998-08-06 | The General Hospital Corporation | A novel method for treating epidermal or dermal conditions |
| US5773430A (en) * | 1997-03-13 | 1998-06-30 | Research Foundation Of State University Of New York | Serine proteinase inhibitory activity by hydrophobic tetracycline |
| AU2001599A (en) * | 1997-12-19 | 1999-07-05 | New York University | Method for inhibiting cyclooxygenase-2 and tumor necrosis factor alpha |
| US7189703B2 (en) * | 1998-01-09 | 2007-03-13 | Intracell, Llc | Treatment and diagnosis of alzheimer's disease |
| US6277061B1 (en) * | 1998-03-31 | 2001-08-21 | The Research Foundation Of State University Of New York | Method of inhibiting membrane-type matrix metalloproteinase |
| DE69940227D1 (de) * | 1998-05-08 | 2009-02-12 | Univ Miami | Verwendung von sub-antimikrobiellen tetracyclinen zur Behandlung von okularer Rosacea |
| PT102160B (pt) * | 1998-05-26 | 2001-04-30 | Hovione Sociedade Quimica S A | Processo para a preparacao de 4-(des-dimetilamino)-tetraciclinas |
| US6432934B1 (en) * | 1998-08-06 | 2002-08-13 | Advanced Vision Research | Methods and compositions for topical treatment of eye surface inflammation and related dry eye disease |
| US6015804A (en) * | 1998-09-11 | 2000-01-18 | The Research Foundation Of State University Of New York | Method of using tetracycline compounds to enhance interleukin-10 production |
| US5977091A (en) * | 1998-09-21 | 1999-11-02 | The Research Foundation Of State University Of New York | Method of preventing acute lung injury |
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| US6506740B1 (en) | 1998-11-18 | 2003-01-14 | Robert A. Ashley | 4-dedimethylaminotetracycline derivatives |
| US6197776B1 (en) * | 1999-03-17 | 2001-03-06 | Ernest L. Bonner, Jr. | Method for treatment of reactive arthritis or bursitis |
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| JP2003520042A (ja) * | 2000-01-24 | 2003-07-02 | アイシス・ファーマシューティカルス・インコーポレーテッド | 誘導性一酸化窒素シンターゼ発現のアンチセンスモジュレーション |
| GB0004531D0 (en) * | 2000-02-25 | 2000-04-19 | Richards Andrew J M | The treatment of respiratory diseases |
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| US20020132798A1 (en) | 2000-06-16 | 2002-09-19 | Nelson Mark L. | 7-phenyl-substituted tetracycline compounds |
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| IL153672A0 (en) * | 2000-07-07 | 2003-07-06 | Tufts College | 7-substituted tetracycline compounds |
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| EA009175B1 (ru) | 2000-07-07 | 2007-12-28 | Трастис Оф Тафтс Коллидж | Замещенные соединения миноциклина, фармацевтическая композиция и способ лечения чувствительного к тетрациклину состояния млекопитающего |
| US7094806B2 (en) * | 2000-07-07 | 2006-08-22 | Trustees Of Tufts College | 7, 8 and 9-substituted tetracycline compounds |
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| KR20130137696A (ko) * | 2007-03-23 | 2013-12-17 | 몰레큘러 리서치 센터, 인크. | 테트라사이클린류를 함유하는 항염증성 조성물 및 이의 치료 용도 |
| EP2216323A3 (en) * | 2007-04-27 | 2010-12-29 | Paratek Pharmaceuticals, Inc. | Methods for synthesizing and purifying aminoalkyl tetracycline compounds |
| EP2176216B1 (en) * | 2007-07-06 | 2012-04-25 | Paratek Pharmaceuticals, Inc. | Methods for synthesizing 9-substituted minocycline |
| TWI680117B (zh) | 2008-05-19 | 2019-12-21 | 派洛泰克藥物股份有限公司 | 四環素化合物之甲苯磺酸鹽及同素異形體 |
| JP2011527708A (ja) | 2008-07-11 | 2011-11-04 | ニュメディックス | 減少した抗菌活性および神経保護作用の利点を有するテトラサイクリン誘導体 |
| WO2010017310A1 (en) | 2008-08-06 | 2010-02-11 | Medicis Pharmaceutical Corporation | Method for the treatment of acne and certain dosage forms thereof |
| KR101746795B1 (ko) | 2008-08-08 | 2017-06-13 | 테트라페이즈 파마슈티컬스, 인코포레이티드 | Ｃ７-플루오로 치환된 테트라시클린 화합물 |
| KR101290745B1 (ko) | 2010-06-03 | 2013-07-29 | 한국해양과학기술원 | 라말린을 함유하는 염증질환 또는 면역질환의 예방 또는 치료용 약학 조성물 |
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| US9561241B1 (en) | 2011-06-28 | 2017-02-07 | Medicis Pharmaceutical Corporation | Gastroretentive dosage forms for minocycline |
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| US10842802B2 (en) | 2013-03-15 | 2020-11-24 | Medicis Pharmaceutical Corporation | Controlled release pharmaceutical dosage forms |
| US9682099B2 (en) | 2015-01-20 | 2017-06-20 | DePuy Synthes Products, Inc. | Compositions and methods for treating joints |
| HUE066360T2 (hu) | 2016-10-19 | 2024-07-28 | Tetraphase Pharmaceuticals Inc | Eravaciklin kristályformái |
| FR3081559B1 (fr) * | 2018-05-28 | 2020-05-08 | Noptrack | Procede pour detecter une pathologie par reperage d'une quantite de no produite par le sujet etudie et appareil pour la mise en œuvre dudit procede |
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|---|---|---|---|---|
| US5478946A (en) * | 1989-06-21 | 1995-12-26 | Abbott Laboratories | Guanidino compounds as regulators of nitric oxide synthase |
| US5216025A (en) * | 1989-09-13 | 1993-06-01 | Board Of Regents, The University Of Texas System | Nitric oxide synthesis inhibitors for potentiating the action of pressor agents in certain hypotensive patients |
| US5358969A (en) * | 1991-12-16 | 1994-10-25 | Washington University | Method of inhibiting nitric oxide formation |
| US5246971A (en) * | 1991-12-16 | 1993-09-21 | Washington University | Method of inhibiting nitric oxide formation |
| US5246970A (en) * | 1991-12-16 | 1993-09-21 | Washington University | Method of inhibiting nitric oxide formation |
| GB9200114D0 (en) * | 1992-01-04 | 1992-02-26 | Scras | Dual inhibitors of no synthase and cyclooxygenase |
| US5296466A (en) * | 1992-02-19 | 1994-03-22 | Board Of Regents, The University Of Texas System | Inhibition of nitric oxide-mediated hypotension and septic shock with iron-containing hemoprotein |
| US5266594A (en) * | 1992-05-12 | 1993-11-30 | Dawson Valina L | Inhibitors of nitric oxide synthase and use thereof to prevent glutamate neurotoxicity |
| US5258371A (en) * | 1992-05-29 | 1993-11-02 | Kuraray Co., Ltd. | Method to reduce connective tissue destruction |
| JPH08503852A (ja) * | 1992-11-25 | 1996-04-30 | ユニバーシティ オブ ピッツバーグ オブ ザ コモンウェルス システム オブハイヤー エデュケーション | ヒト誘導性一酸化窒素シンターゼのｃＤＮＡクローンおよびその作製方法 |
| US5449688A (en) * | 1993-03-30 | 1995-09-12 | The United States Of America As Represented By The Department Of Health And Human Services | Method of treating chronic inflammatory diseases |
-
1996
- 1996-08-30 US US08/697,815 patent/US5789395A/en not_active Expired - Lifetime
-
1997
- 1997-08-21 NZ NZ334512A patent/NZ334512A/xx not_active IP Right Cessation
- 1997-08-21 JP JP51173598A patent/JP4451930B2/ja not_active Expired - Lifetime
- 1997-08-21 WO PCT/US1997/014723 patent/WO1998008480A2/en not_active Ceased
- 1997-08-21 CA CA002670296A patent/CA2670296A1/en not_active Abandoned
- 1997-08-21 EP EP97938501A patent/EP0966525A4/en not_active Ceased
- 1997-08-21 AU AU40808/97A patent/AU718234B2/en not_active Expired
- 1997-08-21 KR KR1019997001591A patent/KR100554859B1/ko not_active Expired - Lifetime
- 1997-08-21 CA CA002264552A patent/CA2264552C/en not_active Expired - Lifetime
-
1998
- 1998-04-16 US US09/061,286 patent/US5919775A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP2002513386A (ja) | 2002-05-08 |
| AU4080897A (en) | 1998-03-19 |
| EP0966525A1 (en) | 1999-12-29 |
| JP4451930B2 (ja) | 2010-04-14 |
| NZ334512A (en) | 2000-09-29 |
| CA2264552A1 (en) | 1998-03-05 |
| CA2670296A1 (en) | 1998-03-05 |
| KR20000035881A (ko) | 2000-06-26 |
| WO1998008480A2 (en) | 1998-03-05 |
| AU718234B2 (en) | 2000-04-13 |
| US5919775A (en) | 1999-07-06 |
| WO1998008480A3 (en) | 2004-07-01 |
| US5789395A (en) | 1998-08-04 |
| EP0966525A4 (en) | 2004-04-14 |
| CA2264552C (en) | 2009-10-13 |
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