JP4451930B2 - 一酸化窒素の生成を阻害するテトラサイクリン化合物の使用方法 - Google Patents

一酸化窒素の生成を阻害するテトラサイクリン化合物の使用方法 Download PDF

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JP4451930B2
JP4451930B2 JP51173598A JP51173598A JP4451930B2 JP 4451930 B2 JP4451930 B2 JP 4451930B2 JP 51173598 A JP51173598 A JP 51173598A JP 51173598 A JP51173598 A JP 51173598A JP 4451930 B2 JP4451930 B2 JP 4451930B2
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cmt
dedimethylaminotetracycline
nitric oxide
mammal
composition
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Japanese (ja)
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JP2002513386A (ja
JP2002513386A5 (https=
Inventor
アショク アール アミン
スティーヴン ビー アブラムソン
ローン エム ゴルーブ
ヌンガヴァラム エス ラママーティー
トーマス エフ マクナマラ
ロバート エイ グリーンワルド
ハワード トラクトマン
Original Assignee
ザ リサーチ ファウンデーション オブ ステイト ユニヴァーシティ オブ ニューヨーク
ホスピタル フォア ジョイント ディジーズス
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Application filed by ザ リサーチ ファウンデーション オブ ステイト ユニヴァーシティ オブ ニューヨーク, ホスピタル フォア ジョイント ディジーズス filed Critical ザ リサーチ ファウンデーション オブ ステイト ユニヴァーシティ オブ ニューヨーク
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
JP51173598A 1996-08-30 1997-08-21 一酸化窒素の生成を阻害するテトラサイクリン化合物の使用方法 Expired - Lifetime JP4451930B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/697,815 US5789395A (en) 1996-08-30 1996-08-30 Method of using tetracycline compounds for inhibition of endogenous nitric oxide production
US08/697,815 1996-08-30
PCT/US1997/014723 WO1998008480A2 (en) 1996-08-30 1997-08-21 Method of using tetracycline compounds for inhibition of nitric oxide production

Publications (3)

Publication Number Publication Date
JP2002513386A JP2002513386A (ja) 2002-05-08
JP2002513386A5 JP2002513386A5 (https=) 2005-04-07
JP4451930B2 true JP4451930B2 (ja) 2010-04-14

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JP51173598A Expired - Lifetime JP4451930B2 (ja) 1996-08-30 1997-08-21 一酸化窒素の生成を阻害するテトラサイクリン化合物の使用方法

Country Status (8)

Country Link
US (2) US5789395A (https=)
EP (1) EP0966525A4 (https=)
JP (1) JP4451930B2 (https=)
KR (1) KR100554859B1 (https=)
AU (1) AU718234B2 (https=)
CA (2) CA2264552C (https=)
NZ (1) NZ334512A (https=)
WO (1) WO1998008480A2 (https=)

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Also Published As

Publication number Publication date
CA2264552C (en) 2009-10-13
EP0966525A1 (en) 1999-12-29
WO1998008480A2 (en) 1998-03-05
US5919775A (en) 1999-07-06
WO1998008480A3 (en) 2004-07-01
AU4080897A (en) 1998-03-19
CA2264552A1 (en) 1998-03-05
KR100554859B1 (ko) 2006-02-24
AU718234B2 (en) 2000-04-13
KR20000035881A (ko) 2000-06-26
JP2002513386A (ja) 2002-05-08
EP0966525A4 (en) 2004-04-14
US5789395A (en) 1998-08-04
NZ334512A (en) 2000-09-29
CA2670296A1 (en) 1998-03-05

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