|
US5605798A
(en)
|
1993-01-07 |
1997-02-25 |
Sequenom, Inc. |
DNA diagnostic based on mass spectrometry
|
|
CA2248084A1
(en)
*
|
1996-03-04 |
1997-09-12 |
Genetrace Systems, Inc. |
Methods of screening nucleic acids using mass spectrometry
|
|
US6605447B2
(en)
*
|
1996-03-15 |
2003-08-12 |
Yale University |
Methods and means of detecting nitric oxide synthase
|
|
US5965363A
(en)
|
1996-09-19 |
1999-10-12 |
Genetrace Systems Inc. |
Methods of preparing nucleic acids for mass spectrometric analysis
|
|
DE69738206T2
(de)
|
1996-11-06 |
2008-07-17 |
Sequenom, Inc., San Diego |
DNA-Diagnostik mittels Massenspektrometrie
|
|
DE69735445T2
(de)
|
1996-12-10 |
2006-08-10 |
Sequenom, Inc., San Diego |
Abspaltbare, nicht-flüchtige moleküle zur massenmarkierung
|
|
WO1998033379A1
(en)
*
|
1997-02-04 |
1998-08-06 |
The General Hospital Corporation |
A novel method for treating epidermal or dermal conditions
|
|
US5773430A
(en)
*
|
1997-03-13 |
1998-06-30 |
Research Foundation Of State University Of New York |
Serine proteinase inhibitory activity by hydrophobic tetracycline
|
|
AU2001599A
(en)
*
|
1997-12-19 |
1999-07-05 |
New York University |
Method for inhibiting cyclooxygenase-2 and tumor necrosis factor alpha
|
|
US7189703B2
(en)
*
|
1998-01-09 |
2007-03-13 |
Intracell, Llc |
Treatment and diagnosis of alzheimer's disease
|
|
US6277061B1
(en)
*
|
1998-03-31 |
2001-08-21 |
The Research Foundation Of State University Of New York |
Method of inhibiting membrane-type matrix metalloproteinase
|
|
DE69940227D1
(de)
*
|
1998-05-08 |
2009-02-12 |
Univ Miami |
Verwendung von sub-antimikrobiellen tetracyclinen zur Behandlung von okularer Rosacea
|
|
PT102160B
(pt)
*
|
1998-05-26 |
2001-04-30 |
Hovione Sociedade Quimica S A |
Processo para a preparacao de 4-(des-dimetilamino)-tetraciclinas
|
|
US6432934B1
(en)
*
|
1998-08-06 |
2002-08-13 |
Advanced Vision Research |
Methods and compositions for topical treatment of eye surface inflammation and related dry eye disease
|
|
US6015804A
(en)
*
|
1998-09-11 |
2000-01-18 |
The Research Foundation Of State University Of New York |
Method of using tetracycline compounds to enhance interleukin-10 production
|
|
US5977091A
(en)
*
|
1998-09-21 |
1999-11-02 |
The Research Foundation Of State University Of New York |
Method of preventing acute lung injury
|
|
US6946453B2
(en)
|
1998-11-18 |
2005-09-20 |
Collagenex Pharmaceuticals, Inc. |
4-dedimethylaminotracycline derivatives
|
|
US6506740B1
(en)
|
1998-11-18 |
2003-01-14 |
Robert A. Ashley |
4-dedimethylaminotetracycline derivatives
|
|
US6197776B1
(en)
*
|
1999-03-17 |
2001-03-06 |
Ernest L. Bonner, Jr. |
Method for treatment of reactive arthritis or bursitis
|
|
EP1171163A1
(en)
*
|
1999-04-27 |
2002-01-16 |
Antibody Systems, Inc. |
Compositions containing tetracyclines for treating hemorrhagic virus infections and other disorders
|
|
US6500812B2
(en)
|
1999-09-14 |
2002-12-31 |
Paratek Pharmaceuticals, Inc. |
13-substituted methacycline compounds
|
|
US6849615B2
(en)
|
1999-09-14 |
2005-02-01 |
Paratek Pharmaceuticals, Inc. |
13-substituted methacycline compounds
|
|
JP2003510349A
(ja)
*
|
1999-10-07 |
2003-03-18 |
ノヴァ−ニューロン インコーポレーテッド |
線条体機能に必要な遺伝子、その使用、およびそれを調節するための化合物
|
|
AU3105801A
(en)
|
2000-01-24 |
2001-07-31 |
Trustees Of Tufts College |
Tetracycline compounds for treatment of cryptosporidium parvum related disorders
|
|
JP2003520042A
(ja)
*
|
2000-01-24 |
2003-07-02 |
アイシス・ファーマシューティカルス・インコーポレーテッド |
誘導性一酸化窒素シンターゼ発現のアンチセンスモジュレーション
|
|
GB0004531D0
(en)
*
|
2000-02-25 |
2000-04-19 |
Richards Andrew J M |
The treatment of respiratory diseases
|
|
EA200201046A1
(ru)
*
|
2000-03-31 |
2003-04-24 |
Трастис Оф Тафтс Коллидж |
7- или 9-замещенные соединения тетрациклина, способ их получения (варианты), фармацевтическая композиция, способ лечения состояния, чувствительного к действию тетрациклина, у млекопитающего и реакционноспособное промежуточное производное
|
|
US6613756B2
(en)
|
2000-05-05 |
2003-09-02 |
Wisconsin Alumni Research Foundation |
Use of tetracycline derivatives in treating multiple sclerosis
|
|
CA2409063A1
(en)
*
|
2000-05-15 |
2001-11-22 |
Mark L. Nelson |
7-substituted fused ring tetracycline compounds
|
|
AU2001268468A1
(en)
|
2000-06-13 |
2001-12-24 |
The Trustees Of Boston University |
Use of nucleotide analogs in the analysis of oligonucleotide mixtures and in highly multiplexed nucleic acid sequencing
|
|
AU2001268475A1
(en)
*
|
2000-06-16 |
2002-01-02 |
Trustees Of Tufts College |
7-phenyl-substituted tetracycline compounds
|
|
US20040224927A1
(en)
*
|
2000-06-16 |
2004-11-11 |
Trustees Of Tufts College |
7-N-substituted phenyl tetracycline compounds
|
|
US20020132798A1
(en)
|
2000-06-16 |
2002-09-19 |
Nelson Mark L. |
7-phenyl-substituted tetracycline compounds
|
|
US20050143353A1
(en)
*
|
2000-07-07 |
2005-06-30 |
Paratek Pharmaceuticals, Inc. |
13-Substituted methacycline compounds
|
|
IL153672A0
(en)
*
|
2000-07-07 |
2003-07-06 |
Tufts College |
7-substituted tetracycline compounds
|
|
WO2002004404A2
(en)
|
2000-07-07 |
2002-01-17 |
Trustees Of Tufts College |
7,8 and 9-substituted tetracycline compounds
|
|
EA009175B1
(ru)
|
2000-07-07 |
2007-12-28 |
Трастис Оф Тафтс Коллидж |
Замещенные соединения миноциклина, фармацевтическая композиция и способ лечения чувствительного к тетрациклину состояния млекопитающего
|
|
US7094806B2
(en)
*
|
2000-07-07 |
2006-08-22 |
Trustees Of Tufts College |
7, 8 and 9-substituted tetracycline compounds
|
|
WO2002020022A1
(en)
*
|
2000-09-06 |
2002-03-14 |
Neurotherapeutics, Llc |
Method of treating neurologic disorders
|
|
US6955806B2
(en)
*
|
2001-01-18 |
2005-10-18 |
Genzyme Corporation |
Ionene polymers and their use as antimicrobial agents
|
|
US7045349B2
(en)
*
|
2001-01-23 |
2006-05-16 |
Benedict Daniel J |
Method of islet isolation using process control
|
|
EA013835B1
(ru)
|
2001-03-13 |
2010-08-30 |
Пэрэтек Фамэсьютикэлс, Инк. |
Замещенные соединения тетрациклина (варианты), фармацевтическая композиция и способ лечения чувствительного к тетрациклину состояния субъекта
|
|
WO2002072506A2
(en)
|
2001-03-13 |
2002-09-19 |
Paratek Pharmaceuticals, Inc. |
7-pyrollyl tetracycline compounds and methods of use thereof
|
|
US6841546B2
(en)
*
|
2001-03-14 |
2005-01-11 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds as antifungal agents
|
|
EP1381372A2
(en)
|
2001-03-14 |
2004-01-21 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds as synergistic antifungal agents
|
|
EP2311440A1
(en)
*
|
2001-04-05 |
2011-04-20 |
Collagenex Pharmaceuticals, Inc. |
Controlled delivery of tetracycline compounds and tetracycline derivatives
|
|
EP1383508B1
(en)
*
|
2001-04-05 |
2006-06-21 |
Collagenex Pharmaceuticals, Inc. |
Doxycycline for the treatment of acne
|
|
US7211267B2
(en)
|
2001-04-05 |
2007-05-01 |
Collagenex Pharmaceuticals, Inc. |
Methods of treating acne
|
|
ES2338994T3
(es)
*
|
2001-04-24 |
2010-05-14 |
Paratek Pharmaceuticals, Inc. |
Compuestos de tetraciclina sustituida para el tratamiento de la malaria.
|
|
US8088820B2
(en)
*
|
2001-04-24 |
2012-01-03 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds for the treatment of malaria
|
|
GB0114672D0
(en)
|
2001-06-15 |
2001-08-08 |
Orthogenics As |
Pharmaceutical formulations and methods of medical treatment
|
|
US20060194773A1
(en)
*
|
2001-07-13 |
2006-08-31 |
Paratek Pharmaceuticals, Inc. |
Tetracyline compounds having target therapeutic activities
|
|
EP2327409A1
(en)
|
2001-07-13 |
2011-06-01 |
Paratek Pharmaceuticals, Inc. |
Tetracycline compound having target therapeutic activities
|
|
US20110092677A1
(en)
*
|
2001-08-30 |
2011-04-21 |
Biorexis Technology, Inc. |
Modified transferin-antibody fusion proteins
|
|
ES2551708T3
(es)
|
2002-01-08 |
2015-11-23 |
Paratek Pharmaceuticals, Inc. |
Compuestos de 4-desdimetilamino tetraciclina
|
|
US6833139B1
(en)
|
2002-01-09 |
2004-12-21 |
Ferndale Laboratories, Inc. |
Composition and method for the treatment of anorectal disorders
|
|
EP2311451A1
(en)
|
2002-03-08 |
2011-04-20 |
Paratek Pharmaceuticals, Inc. |
Amino-methyl substituted tetracycline compounds
|
|
EP1503981A4
(en)
|
2002-03-21 |
2007-08-15 |
Paratek Pharm Innc |
SUBSTITUTED TETRACYCLINE COMPOUNDS
|
|
WO2003082011A1
(en)
|
2002-03-29 |
2003-10-09 |
The Research Foundation Of State University Of New York |
Use of non-antibacterial tetracycline analogs and formulations thereof for the treatment of bacterial exotoxins
|
|
US6958161B2
(en)
|
2002-04-12 |
2005-10-25 |
F H Faulding & Co Limited |
Modified release coated drug preparation
|
|
US8192749B2
(en)
|
2003-04-16 |
2012-06-05 |
Galderma Laboratories Inc. |
Methods of simultaneously treating ocular rosacea and acne rosacea
|
|
AU2003261161B2
(en)
|
2002-07-12 |
2009-09-10 |
Paratek Pharmaceuticals, Inc |
3, 10, and 12a substituted tetracycline compounds
|
|
CA2491655A1
(en)
*
|
2002-07-12 |
2004-01-22 |
The Research Foundation Of State University Of New York |
Method for reducing c-rective protein levels with non-antibacterial tetracycline formulations
|
|
US20040044220A1
(en)
*
|
2002-08-22 |
2004-03-04 |
University Of Florida |
Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin
|
|
EP1556007A4
(en)
*
|
2002-10-24 |
2008-12-17 |
Paratek Pharm Innc |
SUBSTITUTED TETRACYCLINE COMPOUNDS FOR THE TREATMENT OF MALARIA
|
|
WO2004046109A2
(en)
*
|
2002-11-19 |
2004-06-03 |
Genzyme Corporation |
Ionene oligomers and polymers
|
|
WO2004091483A2
(en)
|
2003-04-07 |
2004-10-28 |
Shire Laboratories, Inc. |
Once daily formulations of tetracyclines
|
|
US20040220242A1
(en)
*
|
2003-05-02 |
2004-11-04 |
Leland Shapiro |
Inhibitors of serine protease activity, methods and compositions for treatment of nitric oxide induced clinical conditions
|
|
US20050143352A1
(en)
|
2003-07-09 |
2005-06-30 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds
|
|
AU2004259661B2
(en)
|
2003-07-09 |
2011-11-10 |
Paratek Pharmaceuticals, Inc. |
Prodrugs of 9-aminomethyl tetracycline compounds
|
|
DE10343887B3
(de)
*
|
2003-09-19 |
2004-12-09 |
Goodwell International Ltd., Tortola |
Snowboardbindung
|
|
JP5010284B2
(ja)
*
|
2004-01-15 |
2012-08-29 |
パラテック ファーマシューティカルズ インコーポレイテッド |
テトラサイクリン化合物の芳香族a環誘導体
|
|
US20050176140A1
(en)
*
|
2004-02-10 |
2005-08-11 |
Benedict Daniel J. |
Method and apparatus for cell culture using a two liquid phase bioreactor
|
|
TWI261038B
(en)
*
|
2004-08-11 |
2006-09-01 |
Bo-Cheng Chen |
Bicycle gear-shifting handgrip
|
|
EP1805134B1
(en)
|
2004-10-25 |
2012-06-20 |
Paratek Pharmaceuticals, Inc. |
4-aminotetracyclines and methods of use thereof
|
|
EP2033950A1
(en)
|
2004-10-25 |
2009-03-11 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds
|
|
US20080242642A1
(en)
|
2007-04-02 |
2008-10-02 |
Medicis Pharmaceutical Corporation |
Minocycline oral dosage forms for the treatment of acne
|
|
US7919483B2
(en)
*
|
2005-06-24 |
2011-04-05 |
Medicis Pharmaceutical Corporation |
Method for the treatment of acne
|
|
US8722650B1
(en)
|
2005-06-24 |
2014-05-13 |
Medicis Pharmaceutical Corporation |
Extended-release minocycline dosage forms
|
|
US8252776B2
(en)
*
|
2007-04-02 |
2012-08-28 |
Medicis Pharmaceutical Corporation |
Minocycline oral dosage forms for the treatment of acne
|
|
US20070093455A1
(en)
*
|
2005-07-21 |
2007-04-26 |
Paul Abato |
10-substituted tetracyclines and methods of use thereof
|
|
WO2008079339A2
(en)
|
2006-12-21 |
2008-07-03 |
Paratek Pharmaceuticals, Inc. |
Tetracycline derivatives for the treatment of bacterial, viral and parasitic infections
|
|
CA2892739A1
(en)
|
2006-12-21 |
2008-07-03 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds for treatment of inflammatory skin disorders
|
|
KR20130137696A
(ko)
*
|
2007-03-23 |
2013-12-17 |
몰레큘러 리서치 센터, 인크. |
테트라사이클린류를 함유하는 항염증성 조성물 및 이의 치료 용도
|
|
EP2216323A3
(en)
*
|
2007-04-27 |
2010-12-29 |
Paratek Pharmaceuticals, Inc. |
Methods for synthesizing and purifying aminoalkyl tetracycline compounds
|
|
EP2176216B1
(en)
*
|
2007-07-06 |
2012-04-25 |
Paratek Pharmaceuticals, Inc. |
Methods for synthesizing 9-substituted minocycline
|
|
TWI680117B
(zh)
|
2008-05-19 |
2019-12-21 |
派洛泰克藥物股份有限公司 |
四環素化合物之甲苯磺酸鹽及同素異形體
|
|
JP2011527708A
(ja)
|
2008-07-11 |
2011-11-04 |
ニュメディックス |
減少した抗菌活性および神経保護作用の利点を有するテトラサイクリン誘導体
|
|
WO2010017310A1
(en)
|
2008-08-06 |
2010-02-11 |
Medicis Pharmaceutical Corporation |
Method for the treatment of acne and certain dosage forms thereof
|
|
KR101746795B1
(ko)
|
2008-08-08 |
2017-06-13 |
테트라페이즈 파마슈티컬스, 인코포레이티드 |
C7-플루오로 치환된 테트라시클린 화합물
|
|
KR101290745B1
(ko)
|
2010-06-03 |
2013-07-29 |
한국해양과학기술원 |
라말린을 함유하는 염증질환 또는 면역질환의 예방 또는 치료용 약학 조성물
|
|
WO2010129057A2
(en)
|
2009-05-08 |
2010-11-11 |
Tetraphase Pharmaceuticals, Inc. |
Tetracycline compounds
|
|
NO2470500T3
(https=)
|
2009-08-28 |
2018-03-03 |
|
|
|
DK2552890T3
(en)
|
2010-03-31 |
2017-04-03 |
Tetraphase Pharmaceuticals Inc |
POLYCYCLIC TETRACYCLINE COMPOUNDS
|
|
US8455436B2
(en)
|
2010-12-28 |
2013-06-04 |
Depuy Mitek, Llc |
Compositions and methods for treating joints
|
|
US8398611B2
(en)
|
2010-12-28 |
2013-03-19 |
Depuy Mitek, Inc. |
Compositions and methods for treating joints
|
|
US8524662B2
(en)
|
2010-12-28 |
2013-09-03 |
Depuy Mitek, Llc |
Compositions and methods for treating joints
|
|
US9255068B2
(en)
|
2011-05-12 |
2016-02-09 |
Warner Chilcott Company, Llc |
Crystalline salts of (4S,4AS,5AR,12AS)-4-dimethylamino-3,10,12,12A-tetrahydroxy-7-[methoxy(methyl)amino)-methyl] acid amide and methods of using the same
|
|
US9561241B1
(en)
|
2011-06-28 |
2017-02-07 |
Medicis Pharmaceutical Corporation |
Gastroretentive dosage forms for minocycline
|
|
US9119793B1
(en)
|
2011-06-28 |
2015-09-01 |
Medicis Pharmaceutical Corporation |
Gastroretentive dosage forms for doxycycline
|
|
US8623839B2
(en)
|
2011-06-30 |
2014-01-07 |
Depuy Mitek, Llc |
Compositions and methods for stabilized polysaccharide formulations
|
|
EP2872146A4
(en)
*
|
2012-07-13 |
2016-01-06 |
Paratek Pharm Innc |
TETRACYCLIN COMPOUNDS FOR THE TREATMENT OF NEURODEEGENERATIVE DISEASES
|
|
CA2883238C
(en)
|
2012-08-31 |
2021-11-23 |
Tetraphase Pharmaceuticals, Inc. |
Tetracycline compounds
|
|
US10842802B2
(en)
|
2013-03-15 |
2020-11-24 |
Medicis Pharmaceutical Corporation |
Controlled release pharmaceutical dosage forms
|
|
US9682099B2
(en)
|
2015-01-20 |
2017-06-20 |
DePuy Synthes Products, Inc. |
Compositions and methods for treating joints
|
|
HUE066360T2
(hu)
|
2016-10-19 |
2024-07-28 |
Tetraphase Pharmaceuticals Inc |
Eravaciklin kristályformái
|
|
FR3081559B1
(fr)
*
|
2018-05-28 |
2020-05-08 |
Noptrack |
Procede pour detecter une pathologie par reperage d'une quantite de no produite par le sujet etudie et appareil pour la mise en œuvre dudit procede
|
|
US12570604B2
(en)
|
2018-11-09 |
2026-03-10 |
Tetraphase Pharmaceuticals, Inc. |
Polymorphic forms of a tetracycline compound and uses thereof
|
|
FR3103901B1
(fr)
|
2019-11-28 |
2023-02-24 |
Noptrack |
Detection d’une espece chimique dans la sueur d’un sujet
|