CA2264552C - Method of using tetracycline compounds for inhibition of nitric oxide production - Google Patents

Method of using tetracycline compounds for inhibition of nitric oxide production Download PDF

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Publication number
CA2264552C
CA2264552C CA002264552A CA2264552A CA2264552C CA 2264552 C CA2264552 C CA 2264552C CA 002264552 A CA002264552 A CA 002264552A CA 2264552 A CA2264552 A CA 2264552A CA 2264552 C CA2264552 C CA 2264552C
Authority
CA
Canada
Prior art keywords
nitric oxide
activity
use according
tetracycline compound
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002264552A
Other languages
English (en)
French (fr)
Other versions
CA2264552A1 (en
Inventor
Ashok R. Amin
Steven B. Abramson
Lorne M. Golub
Nungavaram S. Ramamurthy
Thomas F. Mcnamara
Robert A. Greenwald
Howard Trachtman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hospital for Joint Diseases
Research Foundation of the State University of New York
Original Assignee
Hospital for Joint Diseases
Research Foundation of the State University of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24802673&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2264552(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hospital for Joint Diseases, Research Foundation of the State University of New York filed Critical Hospital for Joint Diseases
Priority to CA002670296A priority Critical patent/CA2670296A1/en
Publication of CA2264552A1 publication Critical patent/CA2264552A1/en
Application granted granted Critical
Publication of CA2264552C publication Critical patent/CA2264552C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
CA002264552A 1996-08-30 1997-08-21 Method of using tetracycline compounds for inhibition of nitric oxide production Expired - Lifetime CA2264552C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002670296A CA2670296A1 (en) 1996-08-30 1997-08-21 Method of using tetracycline compounds for inhibition of nitric oxide production

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/697,815 US5789395A (en) 1996-08-30 1996-08-30 Method of using tetracycline compounds for inhibition of endogenous nitric oxide production
US08/697,815 1996-08-30
PCT/US1997/014723 WO1998008480A2 (en) 1996-08-30 1997-08-21 Method of using tetracycline compounds for inhibition of nitric oxide production

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA002670296A Division CA2670296A1 (en) 1996-08-30 1997-08-21 Method of using tetracycline compounds for inhibition of nitric oxide production

Publications (2)

Publication Number Publication Date
CA2264552A1 CA2264552A1 (en) 1998-03-05
CA2264552C true CA2264552C (en) 2009-10-13

Family

ID=24802673

Family Applications (2)

Application Number Title Priority Date Filing Date
CA002264552A Expired - Lifetime CA2264552C (en) 1996-08-30 1997-08-21 Method of using tetracycline compounds for inhibition of nitric oxide production
CA002670296A Abandoned CA2670296A1 (en) 1996-08-30 1997-08-21 Method of using tetracycline compounds for inhibition of nitric oxide production

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA002670296A Abandoned CA2670296A1 (en) 1996-08-30 1997-08-21 Method of using tetracycline compounds for inhibition of nitric oxide production

Country Status (8)

Country Link
US (2) US5789395A (https=)
EP (1) EP0966525A4 (https=)
JP (1) JP4451930B2 (https=)
KR (1) KR100554859B1 (https=)
AU (1) AU718234B2 (https=)
CA (2) CA2264552C (https=)
NZ (1) NZ334512A (https=)
WO (1) WO1998008480A2 (https=)

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US5965363A (en) 1996-09-19 1999-10-12 Genetrace Systems Inc. Methods of preparing nucleic acids for mass spectrometric analysis
EP1164203B1 (en) 1996-11-06 2007-10-10 Sequenom, Inc. DNA Diagnostics based on mass spectrometry
EP0963443B1 (en) 1996-12-10 2006-03-08 Sequenom, Inc. Releasable nonvolatile mass-label molecules
AU6139798A (en) * 1997-02-04 1998-08-25 General Hospital Corporation, The A novel method for treating epidermal or dermal conditions
US5773430A (en) * 1997-03-13 1998-06-30 Research Foundation Of State University Of New York Serine proteinase inhibitory activity by hydrophobic tetracycline
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US7189703B2 (en) * 1998-01-09 2007-03-13 Intracell, Llc Treatment and diagnosis of alzheimer's disease
US6277061B1 (en) * 1998-03-31 2001-08-21 The Research Foundation Of State University Of New York Method of inhibiting membrane-type matrix metalloproteinase
US6455583B1 (en) * 1998-05-08 2002-09-24 The University Of Miami Method for treating meibomian gland disease
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US6432934B1 (en) * 1998-08-06 2002-08-13 Advanced Vision Research Methods and compositions for topical treatment of eye surface inflammation and related dry eye disease
US6015804A (en) * 1998-09-11 2000-01-18 The Research Foundation Of State University Of New York Method of using tetracycline compounds to enhance interleukin-10 production
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Also Published As

Publication number Publication date
JP4451930B2 (ja) 2010-04-14
EP0966525A1 (en) 1999-12-29
WO1998008480A2 (en) 1998-03-05
US5919775A (en) 1999-07-06
WO1998008480A3 (en) 2004-07-01
AU4080897A (en) 1998-03-19
CA2264552A1 (en) 1998-03-05
KR100554859B1 (ko) 2006-02-24
AU718234B2 (en) 2000-04-13
KR20000035881A (ko) 2000-06-26
JP2002513386A (ja) 2002-05-08
EP0966525A4 (en) 2004-04-14
US5789395A (en) 1998-08-04
NZ334512A (en) 2000-09-29
CA2670296A1 (en) 1998-03-05

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