KR100363003B1 - 옥소피리디닐퀴녹살린유도체 - Google Patents

옥소피리디닐퀴녹살린유도체 Download PDF

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Publication number
KR100363003B1
KR100363003B1 KR1019950008201A KR19950008201A KR100363003B1 KR 100363003 B1 KR100363003 B1 KR 100363003B1 KR 1019950008201 A KR1019950008201 A KR 1019950008201A KR 19950008201 A KR19950008201 A KR 19950008201A KR 100363003 B1 KR100363003 B1 KR 100363003B1
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KR
South Korea
Prior art keywords
nitro
halogen
hydrogen
substituted
alkyl
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Expired - Fee Related
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KR1019950008201A
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English (en)
Korean (ko)
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KR950032171A (ko
Inventor
수수무타카다
쵸메이 노부오
마코토아다치
마사미에이죠
카주오카와사키
Original Assignee
시오노기 앤드 컴파니, 리미티드
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Publication of KR950032171A publication Critical patent/KR950032171A/ko
Application granted granted Critical
Publication of KR100363003B1 publication Critical patent/KR100363003B1/ko
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1019950008201A 1994-04-08 1995-04-08 옥소피리디닐퀴녹살린유도체 Expired - Fee Related KR100363003B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP7090994 1994-04-08
JP94-70909 1994-04-08

Publications (2)

Publication Number Publication Date
KR950032171A KR950032171A (ko) 1995-12-20
KR100363003B1 true KR100363003B1 (ko) 2003-02-11

Family

ID=13445121

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019950008201A Expired - Fee Related KR100363003B1 (ko) 1994-04-08 1995-04-08 옥소피리디닐퀴녹살린유도체

Country Status (14)

Country Link
US (1) US5677305A (enExample)
EP (1) EP0676397B1 (enExample)
KR (1) KR100363003B1 (enExample)
CN (1) CN1044241C (enExample)
AT (1) ATE185806T1 (enExample)
AU (1) AU688459B2 (enExample)
CA (1) CA2146478A1 (enExample)
DE (1) DE69512816T2 (enExample)
DK (1) DK0676397T3 (enExample)
ES (1) ES2140620T3 (enExample)
GR (1) GR3032406T3 (enExample)
HU (1) HUT72064A (enExample)
TW (1) TW300894B (enExample)
ZA (1) ZA952841B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU688459B2 (en) * 1994-04-08 1998-03-12 Shionogi & Co., Ltd. Oxopyridinylquinoxaline derivative
AUPN842196A0 (en) * 1996-03-05 1996-03-28 Fujisawa Pharmaceutical Co., Ltd. New compound
CN1161344C (zh) * 1997-09-01 2004-08-11 杏林制药株式会社 6,7-非对称二取代喹喔啉羧酸衍生物及其加成盐以及它们的制备方法
CN1304404A (zh) 1998-06-01 2001-07-18 盐野义制药株式会社 氰基亚氨基喹喔啉衍生物
US8039637B2 (en) 2005-06-23 2011-10-18 Array Biopharma Inc. Process for preparing benzimidazole compounds
US20100113461A1 (en) * 2008-10-29 2010-05-06 Gilead Palo Alto, Inc. Substituted heterocyclic compounds
US20100113514A1 (en) 2008-10-30 2010-05-06 Gilead Palo Alto, Inc. Fused heterocyclic compounds as ion channel modulators
EP2338492A1 (en) 2009-12-24 2011-06-29 Universidad del Pais Vasco Methods and compositions for the treatment of alzheimer
CN103664806B (zh) * 2013-12-16 2016-06-29 山东汇海医药化工有限公司 一种n-乙酰乙酰基-6-甲氧基-7-氨基喹喔啉-2，3-二酮的制备方法
EP3589616A1 (en) 2017-02-28 2020-01-08 Universitat Autònoma de Barcelona (nitro-phenyl)-nitropyridine compounds for treating synucleinopathies
WO2019161917A1 (en) 2018-02-23 2019-08-29 Universitat Autonoma De Barcelona 4-substituted 1-ethenylsulfonyl-2-nitrobenzene compounds for treating synucleinopathies
WO2024083850A1 (en) 2022-10-18 2024-04-25 ETH Zürich Electrocatalyst

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04193876A (ja) * 1990-11-26 1992-07-13 Sumitomo Chem Co Ltd キノキザリン誘導体、その製造法およびそれを有効成分とする除草剤
US5153195A (en) * 1988-12-22 1992-10-06 Novo Nordisk A/S Quinoxaline compounds and their preparation and use
JPH06228112A (ja) * 1993-02-05 1994-08-16 Yamanouchi Pharmaceut Co Ltd （１ｈ，４ｈ）キノキサリン誘導体
EP0676397A1 (en) * 1994-04-08 1995-10-11 Shionogi & Co., Ltd. Oxopyridinylquinoxaline derivatives

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE66149B1 (en) * 1986-09-16 1995-12-13 Novo Nordisk As Quinoxaline compounds and their preparation and use
JP2635662B2 (ja) * 1987-03-23 1997-07-30 ノボ・ノルデイスク・アクツイエルスカブ ヘテロ環状化合物，その製造方法及びその使用法
NO179551C (no) * 1987-11-10 1996-10-30 Novo Nordisk As Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelser
DK160941C (da) * 1988-06-28 1991-10-21 Novo Nordisk As Kondenserede 2,3-dihydroxypyraziner, fremgangsmaade til deres fremstilling og farmaceutiske praeparater, hvori forbindelserne indgaar
DK716188D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Quinoxalinforbindelser, deres fremstilling og anvendelse
DK715888D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Quinoxalinforbindelser, deres fremstilling og anvendelse
HU221425B (en) * 1990-11-06 2002-10-28 Yamanouchi Pharma Co Ltd Condensed pyrazine derivatives, process for their production and pharmaceutical preparations containing these compounds
DK73091D0 (da) * 1991-04-22 1991-04-22 Novo Nordisk As Quinoxalinforbindelser, deres fremstilling og anvendelse
DE4217952A1 (de) * 1992-05-30 1993-12-02 Basf Ag Chinoxalin-2,3(1H,4H)-dione

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5153195A (en) * 1988-12-22 1992-10-06 Novo Nordisk A/S Quinoxaline compounds and their preparation and use
JPH04193876A (ja) * 1990-11-26 1992-07-13 Sumitomo Chem Co Ltd キノキザリン誘導体、その製造法およびそれを有効成分とする除草剤
JPH06228112A (ja) * 1993-02-05 1994-08-16 Yamanouchi Pharmaceut Co Ltd （１ｈ，４ｈ）キノキサリン誘導体
EP0676397A1 (en) * 1994-04-08 1995-10-11 Shionogi & Co., Ltd. Oxopyridinylquinoxaline derivatives

Also Published As

Publication number Publication date
ZA952841B (en) 1995-12-18
GR3032406T3 (en) 2000-05-31
AU688459B2 (en) 1998-03-12
EP0676397A1 (en) 1995-10-11
DE69512816T2 (de) 2000-04-27
DE69512816D1 (de) 1999-11-25
CA2146478A1 (en) 1995-10-09
ES2140620T3 (es) 2000-03-01
KR950032171A (ko) 1995-12-20
US5677305A (en) 1997-10-14
HUT72064A (en) 1996-03-28
TW300894B (enExample) 1997-03-21
EP0676397B1 (en) 1999-10-20
DK0676397T3 (da) 2000-04-03
HU9501026D0 (en) 1995-06-28
CN1044241C (zh) 1999-07-21
AU1625695A (en) 1995-10-19
CN1123792A (zh) 1996-06-05
ATE185806T1 (de) 1999-11-15

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