DK0676397T3 - Oxypyridinylquinoxalinderivater - Google Patents

Oxypyridinylquinoxalinderivater

Info

Publication number
DK0676397T3
DK0676397T3 DK95302326T DK95302326T DK0676397T3 DK 0676397 T3 DK0676397 T3 DK 0676397T3 DK 95302326 T DK95302326 T DK 95302326T DK 95302326 T DK95302326 T DK 95302326T DK 0676397 T3 DK0676397 T3 DK 0676397T3
Authority
DK
Denmark
Prior art keywords
lower alkyl
substituted
nitro
halogen
hydrogen
Prior art date
Application number
DK95302326T
Other languages
English (en)
Inventor
Nobuo Chomei
Kazuo Kawasaki
Susumu Takada
Makoto Adachi
Masami Eigyo
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Application granted granted Critical
Publication of DK0676397T3 publication Critical patent/DK0676397T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Vascular Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
DK95302326T 1994-04-08 1995-04-07 Oxypyridinylquinoxalinderivater DK0676397T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7090994 1994-04-08

Publications (1)

Publication Number Publication Date
DK0676397T3 true DK0676397T3 (da) 2000-04-03

Family

ID=13445121

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95302326T DK0676397T3 (da) 1994-04-08 1995-04-07 Oxypyridinylquinoxalinderivater

Country Status (14)

Country Link
US (1) US5677305A (da)
EP (1) EP0676397B1 (da)
KR (1) KR100363003B1 (da)
CN (1) CN1044241C (da)
AT (1) ATE185806T1 (da)
AU (1) AU688459B2 (da)
CA (1) CA2146478A1 (da)
DE (1) DE69512816T2 (da)
DK (1) DK0676397T3 (da)
ES (1) ES2140620T3 (da)
GR (1) GR3032406T3 (da)
HU (1) HUT72064A (da)
TW (1) TW300894B (da)
ZA (1) ZA952841B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU688459B2 (en) * 1994-04-08 1998-03-12 Shionogi & Co., Ltd. Oxopyridinylquinoxaline derivative
AUPN842196A0 (en) * 1996-03-05 1996-03-28 Fujisawa Pharmaceutical Co., Ltd. New compound
HUP0002853A3 (en) * 1997-09-01 2001-12-28 Kyorin Seiyaku Kk 6,7-asymmetrically disubstituted quinoxalinecarboxylic acid derivatives, and pharmaceutical compositions containing them
NZ508280A (en) 1998-06-01 2002-09-27 Shionogi & Co 2- or 3-cyanoiminoquinoxaline derivatives useful as glutamate receptor antagonists
JP5237798B2 (ja) 2005-06-23 2013-07-17 アレイ バイオファーマ、インコーポレイテッド ベンズイミダゾール化合物の調製方法
WO2010053757A1 (en) 2008-10-29 2010-05-14 Gilead Palo Alto, Inc. 2 -oxoquinoxalin blockers of the late sodium channel
WO2010074807A1 (en) 2008-10-30 2010-07-01 Gilead Palo Alto, Inc. 3, 4-dihydroquinolin-2 ( 1h ) -one derivatives as sodium channel modulators
EP2338492A1 (en) 2009-12-24 2011-06-29 Universidad del Pais Vasco Methods and compositions for the treatment of alzheimer
CN103664806B (zh) * 2013-12-16 2016-06-29 山东汇海医药化工有限公司 一种n-乙酰乙酰基-6-甲氧基-7-氨基喹喔啉-2，3-二酮的制备方法
EP3589616A1 (en) 2017-02-28 2020-01-08 Universitat Autònoma de Barcelona (nitro-phenyl)-nitropyridine compounds for treating synucleinopathies
WO2019161917A1 (en) 2018-02-23 2019-08-29 Universitat Autonoma De Barcelona 4-substituted 1-ethenylsulfonyl-2-nitrobenzene compounds for treating synucleinopathies
WO2024083850A1 (en) 2022-10-18 2024-04-25 ETH Zürich Electrocatalyst

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE66149B1 (en) * 1986-09-16 1995-12-13 Novo Nordisk As Quinoxaline compounds and their preparation and use
JP2635662B2 (ja) * 1987-03-23 1997-07-30 ノボ・ノルデイスク・アクツイエルスカブ ヘテロ環状化合物，その製造方法及びその使用法
NO179551C (no) * 1987-11-10 1996-10-30 Novo Nordisk As Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelser
DK160941C (da) * 1988-06-28 1991-10-21 Novo Nordisk As Kondenserede 2,3-dihydroxypyraziner, fremgangsmaade til deres fremstilling og farmaceutiske praeparater, hvori forbindelserne indgaar
DK716188D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Quinoxalinforbindelser, deres fremstilling og anvendelse
US5153195A (en) * 1988-12-22 1992-10-06 Novo Nordisk A/S Quinoxaline compounds and their preparation and use
DK715888D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Quinoxalinforbindelser, deres fremstilling og anvendelse
JP2550456B2 (ja) * 1990-11-06 1996-11-06 山之内製薬株式会社 縮合ピラジン誘導体
JPH04193876A (ja) * 1990-11-26 1992-07-13 Sumitomo Chem Co Ltd キノキザリン誘導体、その製造法およびそれを有効成分とする除草剤
DK73091D0 (da) * 1991-04-22 1991-04-22 Novo Nordisk As Quinoxalinforbindelser, deres fremstilling og anvendelse
DE4217952A1 (de) * 1992-05-30 1993-12-02 Basf Ag Chinoxalin-2,3(1H,4H)-dione
JPH06228112A (ja) * 1993-02-05 1994-08-16 Yamanouchi Pharmaceut Co Ltd （１ｈ，４ｈ）キノキサリン誘導体
AU688459B2 (en) * 1994-04-08 1998-03-12 Shionogi & Co., Ltd. Oxopyridinylquinoxaline derivative

Also Published As

Publication number Publication date
KR100363003B1 (ko) 2003-02-11
AU688459B2 (en) 1998-03-12
ATE185806T1 (de) 1999-11-15
HU9501026D0 (en) 1995-06-28
EP0676397B1 (en) 1999-10-20
HUT72064A (en) 1996-03-28
GR3032406T3 (en) 2000-05-31
DE69512816D1 (de) 1999-11-25
KR950032171A (ko) 1995-12-20
CN1044241C (zh) 1999-07-21
DE69512816T2 (de) 2000-04-27
CN1123792A (zh) 1996-06-05
CA2146478A1 (en) 1995-10-09
US5677305A (en) 1997-10-14
EP0676397A1 (en) 1995-10-11
TW300894B (da) 1997-03-21
ES2140620T3 (es) 2000-03-01
AU1625695A (en) 1995-10-19
ZA952841B (en) 1995-12-18

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