DE69512816D1 - Oxopyridylchinoxalin Derivate - Google Patents

Oxopyridylchinoxalin Derivate

Info

Publication number
DE69512816D1
DE69512816D1 DE69512816T DE69512816T DE69512816D1 DE 69512816 D1 DE69512816 D1 DE 69512816D1 DE 69512816 T DE69512816 T DE 69512816T DE 69512816 T DE69512816 T DE 69512816T DE 69512816 D1 DE69512816 D1 DE 69512816D1
Authority
DE
Germany
Prior art keywords
lower alkyl
substituted
nitro
halogen
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69512816T
Other languages
English (en)
Other versions
DE69512816T2 (de
Inventor
Susumu Takada
Nobuo Chomei
Makoto Adachi
Masami Eigyo
Kazuo Kawasaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Publication of DE69512816D1 publication Critical patent/DE69512816D1/de
Application granted granted Critical
Publication of DE69512816T2 publication Critical patent/DE69512816T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Vascular Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69512816T 1994-04-08 1995-04-07 Oxopyridylchinoxalin Derivate Expired - Fee Related DE69512816T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7090994 1994-04-08

Publications (2)

Publication Number Publication Date
DE69512816D1 true DE69512816D1 (de) 1999-11-25
DE69512816T2 DE69512816T2 (de) 2000-04-27

Family

ID=13445121

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69512816T Expired - Fee Related DE69512816T2 (de) 1994-04-08 1995-04-07 Oxopyridylchinoxalin Derivate

Country Status (14)

Country Link
US (1) US5677305A (de)
EP (1) EP0676397B1 (de)
KR (1) KR100363003B1 (de)
CN (1) CN1044241C (de)
AT (1) ATE185806T1 (de)
AU (1) AU688459B2 (de)
CA (1) CA2146478A1 (de)
DE (1) DE69512816T2 (de)
DK (1) DK0676397T3 (de)
ES (1) ES2140620T3 (de)
GR (1) GR3032406T3 (de)
HU (1) HUT72064A (de)
TW (1) TW300894B (de)
ZA (1) ZA952841B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU688459B2 (en) * 1994-04-08 1998-03-12 Shionogi & Co., Ltd. Oxopyridinylquinoxaline derivative
AUPN842196A0 (en) * 1996-03-05 1996-03-28 Fujisawa Pharmaceutical Co., Ltd. New compound
WO1999011632A1 (fr) * 1997-09-01 1999-03-11 Kyorin Pharmaceutical Co., Ltd. Derives d'acide quinoxalinecarboxylique disubstitues en position 6,7-asymetrique, sels d'addition de ces derives, et procedes de preparation de ces derives et de ces sels
IL139783A0 (en) 1998-06-01 2002-02-10 Shionogi & Co Cyanoiminoquinoxaline derivates
BRPI0611993B1 (pt) 2005-06-23 2023-11-28 Array Biopharma, Inc. Compostos de benzimidazol e seu processo de preparação
WO2010053757A1 (en) 2008-10-29 2010-05-14 Gilead Palo Alto, Inc. 2 -oxoquinoxalin blockers of the late sodium channel
WO2010074807A1 (en) 2008-10-30 2010-07-01 Gilead Palo Alto, Inc. 3, 4-dihydroquinolin-2 ( 1h ) -one derivatives as sodium channel modulators
EP2338492A1 (de) 2009-12-24 2011-06-29 Universidad del Pais Vasco Verfahren und Zusammensetzung zur Behandlung von Alzheimer
CN103664806B (zh) * 2013-12-16 2016-06-29 山东汇海医药化工有限公司 一种n-乙酰乙酰基-6-甲氧基-7-氨基喹喔啉-2，3-二酮的制备方法
US20190382346A1 (en) 2017-02-28 2019-12-19 Universitat Autonoma De Barcelona (nitro-phenyl)-nitropyridine compounds for treating synucleinopathies
WO2019161917A1 (en) 2018-02-23 2019-08-29 Universitat Autonoma De Barcelona 4-substituted 1-ethenylsulfonyl-2-nitrobenzene compounds for treating synucleinopathies
WO2024083850A1 (en) 2022-10-18 2024-04-25 ETH Zürich Electrocatalyst

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE66149B1 (en) * 1986-09-16 1995-12-13 Novo Nordisk As Quinoxaline compounds and their preparation and use
JP2635662B2 (ja) * 1987-03-23 1997-07-30 ノボ・ノルデイスク・アクツイエルスカブ ヘテロ環状化合物，その製造方法及びその使用法
NO179551C (no) * 1987-11-10 1996-10-30 Novo Nordisk As Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelser
DK160941C (da) * 1988-06-28 1991-10-21 Novo Nordisk As Kondenserede 2,3-dihydroxypyraziner, fremgangsmaade til deres fremstilling og farmaceutiske praeparater, hvori forbindelserne indgaar
DK715888D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Quinoxalinforbindelser, deres fremstilling og anvendelse
DK716188D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Quinoxalinforbindelser, deres fremstilling og anvendelse
US5153195A (en) * 1988-12-22 1992-10-06 Novo Nordisk A/S Quinoxaline compounds and their preparation and use
ATE194985T1 (de) * 1990-11-06 2000-08-15 Yamanouchi Pharma Co Ltd Kondensiertes pyrazinderivat
JPH04193876A (ja) * 1990-11-26 1992-07-13 Sumitomo Chem Co Ltd キノキザリン誘導体、その製造法およびそれを有効成分とする除草剤
DK73091D0 (da) * 1991-04-22 1991-04-22 Novo Nordisk As Quinoxalinforbindelser, deres fremstilling og anvendelse
DE4217952A1 (de) * 1992-05-30 1993-12-02 Basf Ag Chinoxalin-2,3(1H,4H)-dione
JPH06228112A (ja) * 1993-02-05 1994-08-16 Yamanouchi Pharmaceut Co Ltd （１ｈ，４ｈ）キノキサリン誘導体
AU688459B2 (en) * 1994-04-08 1998-03-12 Shionogi & Co., Ltd. Oxopyridinylquinoxaline derivative

Also Published As

Publication number Publication date
ZA952841B (en) 1995-12-18
KR100363003B1 (ko) 2003-02-11
KR950032171A (ko) 1995-12-20
DK0676397T3 (da) 2000-04-03
EP0676397A1 (de) 1995-10-11
GR3032406T3 (en) 2000-05-31
ATE185806T1 (de) 1999-11-15
EP0676397B1 (de) 1999-10-20
AU1625695A (en) 1995-10-19
AU688459B2 (en) 1998-03-12
ES2140620T3 (es) 2000-03-01
CA2146478A1 (en) 1995-10-09
CN1123792A (zh) 1996-06-05
CN1044241C (zh) 1999-07-21
US5677305A (en) 1997-10-14
TW300894B (de) 1997-03-21
HUT72064A (en) 1996-03-28
HU9501026D0 (en) 1995-06-28
DE69512816T2 (de) 2000-04-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee