KR100305959B1 - 포스폰산디에스테르유도체 - Google Patents

포스폰산디에스테르유도체 Download PDF

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Publication number
KR100305959B1
KR100305959B1 KR1019950701521A KR19950701521A KR100305959B1 KR 100305959 B1 KR100305959 B1 KR 100305959B1 KR 1019950701521 A KR1019950701521 A KR 1019950701521A KR 19950701521 A KR19950701521 A KR 19950701521A KR 100305959 B1 KR100305959 B1 KR 100305959B1
Authority
KR
South Korea
Prior art keywords
group
compound
lower alkyl
phosphonic acid
acid diester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1019950701521A
Other languages
English (en)
Korean (ko)
Other versions
KR950704335A (ko
Inventor
미야따가즈요시
구로기야스히사
쓰다요시히꼬
쓰쓰미가즈히꼬
이와모또다께시
나바지에꼬
Original Assignee
오츠까 요시미쯔
가부시키가이샤 오츠까 세이야꾸 고죠
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 오츠까 요시미쯔, 가부시키가이샤 오츠까 세이야꾸 고죠 filed Critical 오츠까 요시미쯔
Publication of KR950704335A publication Critical patent/KR950704335A/ko
Application granted granted Critical
Publication of KR100305959B1 publication Critical patent/KR100305959B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/6552—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
    • C07F9/65522—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
KR1019950701521A 1993-08-20 1994-08-08 포스폰산디에스테르유도체 Expired - Fee Related KR100305959B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP93-206259 1993-08-20
JP20625993 1993-08-20
PCT/JP1994/001307 WO1995006051A1 (en) 1993-08-20 1994-08-08 Phosphonic diester derivative

Publications (2)

Publication Number Publication Date
KR950704335A KR950704335A (ko) 1995-11-17
KR100305959B1 true KR100305959B1 (ko) 2001-12-28

Family

ID=16520375

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019950701521A Expired - Fee Related KR100305959B1 (ko) 1993-08-20 1994-08-08 포스폰산디에스테르유도체

Country Status (12)

Country Link
US (1) US5527786A (enExample)
EP (1) EP0666265B1 (enExample)
JP (1) JP3074332B2 (enExample)
KR (1) KR100305959B1 (enExample)
CN (1) CN1043897C (enExample)
AT (1) ATE189224T1 (enExample)
AU (1) AU678276B2 (enExample)
CA (1) CA2147375C (enExample)
DE (1) DE69422793T2 (enExample)
ES (1) ES2141830T3 (enExample)
TW (1) TW268008B (enExample)
WO (1) WO1995006051A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3533542B2 (ja) * 1994-03-08 2004-05-31 株式会社大塚製薬工場 ホスホン酸ジエステル誘導体
EP2424541A2 (en) * 2009-04-27 2012-03-07 Limerick BioPharma, Inc. Phosphorylated and phosphonated pyrone analogs for therapeutic treatment

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH471113A (de) * 1965-01-29 1969-04-15 Merck Ag E Verfahren zur Herstellung von wasserlöslichen Flavanoidderivaten
AU523040B2 (en) * 1978-05-15 1982-07-08 Kanebo Limited Calcium -antagonistic composition
US4434162A (en) * 1981-02-17 1984-02-28 Kanebo, Ltd. Phosphonic acid ester, pharmaceutical compositions containing the same and method of using the same
JPS5851958B2 (ja) * 1982-01-30 1983-11-19 カネボウ株式会社 新規１−（ベンゾチアゾ−ル−２−イル）−４−ジエトキシ−又はジイソプロポキシ−ホスフイニルベンゼン
US4870199A (en) * 1986-04-30 1989-09-26 Sandoz Pharm. Corp. Processes for the synthesis of diprotected R[R*,S*]-3,5-dihydroxy-6-oxohexanoate esters
JPH0651625B2 (ja) * 1986-12-29 1994-07-06 株式会社大塚製薬工場 高脂質血症治療剤
US4822780A (en) * 1987-07-08 1989-04-18 Otsuka Pharmaceutical Factory, Inc. Carboxamide compounds
AU606808B2 (en) * 1988-06-29 1991-02-14 Otsuka Pharmaceutical Factory, Inc. Arylcarboxamide substituted by alkylphosphonates, process for preparing the same and a pharmaceutical composition containing the same
JP2584336B2 (ja) * 1989-05-30 1997-02-26 株式会社大塚製薬工場 カルボン酸アミド誘導体
JP2549950B2 (ja) * 1991-01-24 1996-10-30 株式会社大塚製薬工場 イミダゾ［１，２−ａ］ピリジン誘導体、その製造方法及びその中間体としてのα−ハロケトン誘導体
JP2696150B2 (ja) * 1991-02-05 1998-01-14 株式会社大塚製薬工場 キノリン誘導体
JP2869608B2 (ja) * 1992-04-28 1999-03-10 株式会社大塚製薬工場 ホスホン酸ジエステル誘導体

Also Published As

Publication number Publication date
EP0666265A4 (en) 1996-04-17
ES2141830T3 (es) 2000-04-01
EP0666265B1 (en) 2000-01-26
AU678276B2 (en) 1997-05-22
WO1995006051A1 (en) 1995-03-02
DE69422793T2 (de) 2000-06-21
CA2147375A1 (en) 1995-03-02
AU7276394A (en) 1995-03-21
US5527786A (en) 1996-06-18
DE69422793D1 (de) 2000-03-02
CN1043897C (zh) 1999-06-30
TW268008B (enExample) 1996-01-11
ATE189224T1 (de) 2000-02-15
CN1114835A (zh) 1996-01-10
CA2147375C (en) 2003-02-11
EP0666265A1 (en) 1995-08-09
JP3074332B2 (ja) 2000-08-07
KR950704335A (ko) 1995-11-17

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