ATE189224T1 - Phosphonsäurediester-derivat - Google Patents
Phosphonsäurediester-derivatInfo
- Publication number
- ATE189224T1 ATE189224T1 AT94923088T AT94923088T ATE189224T1 AT E189224 T1 ATE189224 T1 AT E189224T1 AT 94923088 T AT94923088 T AT 94923088T AT 94923088 T AT94923088 T AT 94923088T AT E189224 T1 ATE189224 T1 AT E189224T1
- Authority
- AT
- Austria
- Prior art keywords
- halogeno
- represents hydrogen
- phosphonic acid
- diester derivative
- acid diester
- Prior art date
Links
- -1 PHOSPHONIC ACID DIESTER Chemical class 0.000 title abstract 3
- 125000005843 halogen group Chemical group 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 208000001953 Hypotension Diseases 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 150000005690 diesters Chemical class 0.000 abstract 1
- 201000005577 familial hyperlipidemia Diseases 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 230000000055 hyoplipidemic effect Effects 0.000 abstract 1
- 230000002218 hypoglycaemic effect Effects 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/6552—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
- C07F9/65522—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP20625993 | 1993-08-20 | ||
| PCT/JP1994/001307 WO1995006051A1 (fr) | 1993-08-20 | 1994-08-08 | Derive de diester phosphonique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE189224T1 true ATE189224T1 (de) | 2000-02-15 |
Family
ID=16520375
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94923088T ATE189224T1 (de) | 1993-08-20 | 1994-08-08 | Phosphonsäurediester-derivat |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5527786A (de) |
| EP (1) | EP0666265B1 (de) |
| JP (1) | JP3074332B2 (de) |
| KR (1) | KR100305959B1 (de) |
| CN (1) | CN1043897C (de) |
| AT (1) | ATE189224T1 (de) |
| AU (1) | AU678276B2 (de) |
| CA (1) | CA2147375C (de) |
| DE (1) | DE69422793T2 (de) |
| ES (1) | ES2141830T3 (de) |
| TW (1) | TW268008B (de) |
| WO (1) | WO1995006051A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3533542B2 (ja) * | 1994-03-08 | 2004-05-31 | 株式会社大塚製薬工場 | ホスホン酸ジエステル誘導体 |
| WO2010129138A2 (en) * | 2009-04-27 | 2010-11-11 | Limerick Biopharma | Phosphorylated and phosphonated pyrone analogs for therapeutic treatment |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH471113A (de) * | 1965-01-29 | 1969-04-15 | Merck Ag E | Verfahren zur Herstellung von wasserlöslichen Flavanoidderivaten |
| AU523040B2 (en) * | 1978-05-15 | 1982-07-08 | Kanebo Limited | Calcium -antagonistic composition |
| US4434162A (en) * | 1981-02-17 | 1984-02-28 | Kanebo, Ltd. | Phosphonic acid ester, pharmaceutical compositions containing the same and method of using the same |
| JPS5851958B2 (ja) * | 1982-01-30 | 1983-11-19 | カネボウ株式会社 | 新規１−（ベンゾチアゾ−ル−２−イル）−４−ジエトキシ−又はジイソプロポキシ−ホスフイニルベンゼン |
| US4870199A (en) * | 1986-04-30 | 1989-09-26 | Sandoz Pharm. Corp. | Processes for the synthesis of diprotected R[R*,S*]-3,5-dihydroxy-6-oxohexanoate esters |
| JPH0651625B2 (ja) * | 1986-12-29 | 1994-07-06 | 株式会社大塚製薬工場 | 高脂質血症治療剤 |
| US4822780A (en) * | 1987-07-08 | 1989-04-18 | Otsuka Pharmaceutical Factory, Inc. | Carboxamide compounds |
| AU606808B2 (en) * | 1988-06-29 | 1991-02-14 | Otsuka Pharmaceutical Factory, Inc. | Arylcarboxamide substituted by alkylphosphonates, process for preparing the same and a pharmaceutical composition containing the same |
| JP2584336B2 (ja) * | 1989-05-30 | 1997-02-26 | 株式会社大塚製薬工場 | カルボン酸アミド誘導体 |
| JP2549950B2 (ja) * | 1991-01-24 | 1996-10-30 | 株式会社大塚製薬工場 | イミダゾ［１，２−ａ］ピリジン誘導体、その製造方法及びその中間体としてのα−ハロケトン誘導体 |
| JP2696150B2 (ja) * | 1991-02-05 | 1998-01-14 | 株式会社大塚製薬工場 | キノリン誘導体 |
| JP2869608B2 (ja) * | 1992-04-28 | 1999-03-10 | 株式会社大塚製薬工場 | ホスホン酸ジエステル誘導体 |
-
1994
- 1994-08-08 KR KR1019950701521A patent/KR100305959B1/ko not_active IP Right Cessation
- 1994-08-08 WO PCT/JP1994/001307 patent/WO1995006051A1/ja active IP Right Grant
- 1994-08-08 US US08/424,345 patent/US5527786A/en not_active Expired - Fee Related
- 1994-08-08 ES ES94923088T patent/ES2141830T3/es not_active Expired - Lifetime
- 1994-08-08 AU AU72763/94A patent/AU678276B2/en not_active Ceased
- 1994-08-08 EP EP94923088A patent/EP0666265B1/de not_active Expired - Lifetime
- 1994-08-08 CA CA002147375A patent/CA2147375C/en not_active Expired - Fee Related
- 1994-08-08 AT AT94923088T patent/ATE189224T1/de not_active IP Right Cessation
- 1994-08-08 CN CN94190705A patent/CN1043897C/zh not_active Expired - Fee Related
- 1994-08-08 JP JP07507465A patent/JP3074332B2/ja not_active Expired - Fee Related
- 1994-08-08 DE DE69422793T patent/DE69422793T2/de not_active Expired - Fee Related
- 1994-08-17 TW TW083107546A patent/TW268008B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| EP0666265A1 (de) | 1995-08-09 |
| CN1043897C (zh) | 1999-06-30 |
| KR950704335A (ko) | 1995-11-17 |
| EP0666265B1 (de) | 2000-01-26 |
| CA2147375C (en) | 2003-02-11 |
| US5527786A (en) | 1996-06-18 |
| DE69422793T2 (de) | 2000-06-21 |
| ES2141830T3 (es) | 2000-04-01 |
| DE69422793D1 (de) | 2000-03-02 |
| AU7276394A (en) | 1995-03-21 |
| KR100305959B1 (ko) | 2001-12-28 |
| AU678276B2 (en) | 1997-05-22 |
| TW268008B (de) | 1996-01-11 |
| JP3074332B2 (ja) | 2000-08-07 |
| CA2147375A1 (en) | 1995-03-02 |
| CN1114835A (zh) | 1996-01-10 |
| WO1995006051A1 (fr) | 1995-03-02 |
| EP0666265A4 (de) | 1996-04-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |