DE69422793D1 - Phosphonsäurediester-derivat - Google Patents

Phosphonsäurediester-derivat

Info

Publication number
DE69422793D1
DE69422793D1 DE69422793T DE69422793T DE69422793D1 DE 69422793 D1 DE69422793 D1 DE 69422793D1 DE 69422793 T DE69422793 T DE 69422793T DE 69422793 T DE69422793 T DE 69422793T DE 69422793 D1 DE69422793 D1 DE 69422793D1
Authority
DE
Germany
Prior art keywords
halogeno
represents hydrogen
lower alkyl
acid derivative
phosphonic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69422793T
Other languages
English (en)
Other versions
DE69422793T2 (de
Inventor
Kazuyoshi Miyata
Yasuhisa Kurogi
Yoshihiko Tsuda
Kazuhiko Tsutsumi
Takeshi Iwamoto
Chieko Naba
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE69422793D1 publication Critical patent/DE69422793D1/de
Publication of DE69422793T2 publication Critical patent/DE69422793T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/6552—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
    • C07F9/65522—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DE69422793T 1993-08-20 1994-08-08 Phosphonsäurediester-derivat Expired - Fee Related DE69422793T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP20625993 1993-08-20
PCT/JP1994/001307 WO1995006051A1 (fr) 1993-08-20 1994-08-08 Derive de diester phosphonique

Publications (2)

Publication Number Publication Date
DE69422793D1 true DE69422793D1 (de) 2000-03-02
DE69422793T2 DE69422793T2 (de) 2000-06-21

Family

ID=16520375

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69422793T Expired - Fee Related DE69422793T2 (de) 1993-08-20 1994-08-08 Phosphonsäurediester-derivat

Country Status (12)

Country Link
US (1) US5527786A (de)
EP (1) EP0666265B1 (de)
JP (1) JP3074332B2 (de)
KR (1) KR100305959B1 (de)
CN (1) CN1043897C (de)
AT (1) ATE189224T1 (de)
AU (1) AU678276B2 (de)
CA (1) CA2147375C (de)
DE (1) DE69422793T2 (de)
ES (1) ES2141830T3 (de)
TW (1) TW268008B (de)
WO (1) WO1995006051A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3533542B2 (ja) * 1994-03-08 2004-05-31 株式会社大塚製薬工場 ホスホン酸ジエステル誘導体
WO2010129138A2 (en) * 2009-04-27 2010-11-11 Limerick Biopharma Phosphorylated and phosphonated pyrone analogs for therapeutic treatment

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH471113A (de) * 1965-01-29 1969-04-15 Merck Ag E Verfahren zur Herstellung von wasserlöslichen Flavanoidderivaten
AU523040B2 (en) * 1978-05-15 1982-07-08 Kanebo Limited Calcium -antagonistic composition
US4434162A (en) * 1981-02-17 1984-02-28 Kanebo, Ltd. Phosphonic acid ester, pharmaceutical compositions containing the same and method of using the same
JPS5851958B2 (ja) * 1982-01-30 1983-11-19 カネボウ株式会社 新規１−（ベンゾチアゾ−ル−２−イル）−４−ジエトキシ−又はジイソプロポキシ−ホスフイニルベンゼン
US4870199A (en) * 1986-04-30 1989-09-26 Sandoz Pharm. Corp. Processes for the synthesis of diprotected R[R*,S*]-3,5-dihydroxy-6-oxohexanoate esters
JPH0651625B2 (ja) * 1986-12-29 1994-07-06 株式会社大塚製薬工場 高脂質血症治療剤
US4822780A (en) * 1987-07-08 1989-04-18 Otsuka Pharmaceutical Factory, Inc. Carboxamide compounds
AU606808B2 (en) * 1988-06-29 1991-02-14 Otsuka Pharmaceutical Factory, Inc. Arylcarboxamide substituted by alkylphosphonates, process for preparing the same and a pharmaceutical composition containing the same
JP2584336B2 (ja) * 1989-05-30 1997-02-26 株式会社大塚製薬工場 カルボン酸アミド誘導体
JP2549950B2 (ja) * 1991-01-24 1996-10-30 株式会社大塚製薬工場 イミダゾ［１，２−ａ］ピリジン誘導体、その製造方法及びその中間体としてのα−ハロケトン誘導体
JP2696150B2 (ja) * 1991-02-05 1998-01-14 株式会社大塚製薬工場 キノリン誘導体
JP2869608B2 (ja) * 1992-04-28 1999-03-10 株式会社大塚製薬工場 ホスホン酸ジエステル誘導体

Also Published As

Publication number Publication date
EP0666265A1 (de) 1995-08-09
CN1043897C (zh) 1999-06-30
KR950704335A (ko) 1995-11-17
EP0666265B1 (de) 2000-01-26
CA2147375C (en) 2003-02-11
US5527786A (en) 1996-06-18
DE69422793T2 (de) 2000-06-21
ES2141830T3 (es) 2000-04-01
AU7276394A (en) 1995-03-21
KR100305959B1 (ko) 2001-12-28
AU678276B2 (en) 1997-05-22
TW268008B (de) 1996-01-11
ATE189224T1 (de) 2000-02-15
JP3074332B2 (ja) 2000-08-07
CA2147375A1 (en) 1995-03-02
CN1114835A (zh) 1996-01-10
WO1995006051A1 (fr) 1995-03-02
EP0666265A4 (de) 1996-04-17

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee