AU678276B2 - Phosphonic diester derivative - Google Patents

Phosphonic diester derivative

Info

Publication number
AU678276B2
AU678276B2 AU72763/94A AU7276394A AU678276B2 AU 678276 B2 AU678276 B2 AU 678276B2 AU 72763/94 A AU72763/94 A AU 72763/94A AU 7276394 A AU7276394 A AU 7276394A AU 678276 B2 AU678276 B2 AU 678276B2
Authority
AU
Australia
Prior art keywords
halogeno
represents hydrogen
lower alkyl
diester derivative
phosphonic diester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU72763/94A
Other languages
English (en)
Other versions
AU7276394A (en
Inventor
Takeshi Iwamoto
Yasuhisa Kurogi
Kazuyoshi Miyata
Chieko Naba
Yoshihiko Tsuda
Kazuhiko Tsutsumi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Factory Inc
Original Assignee
Otsuka Pharmaceutical Co Ltd
Otsuka Pharmaceutical Factory Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd, Otsuka Pharmaceutical Factory Inc filed Critical Otsuka Pharmaceutical Co Ltd
Publication of AU7276394A publication Critical patent/AU7276394A/en
Application granted granted Critical
Publication of AU678276B2 publication Critical patent/AU678276B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/6552—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
    • C07F9/65522—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
AU72763/94A 1993-08-20 1994-08-08 Phosphonic diester derivative Ceased AU678276B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP20625993 1993-08-20
JP5-206259 1993-08-20
PCT/JP1994/001307 WO1995006051A1 (en) 1993-08-20 1994-08-08 Phosphonic diester derivative

Publications (2)

Publication Number Publication Date
AU7276394A AU7276394A (en) 1995-03-21
AU678276B2 true AU678276B2 (en) 1997-05-22

Family

ID=16520375

Family Applications (1)

Application Number Title Priority Date Filing Date
AU72763/94A Ceased AU678276B2 (en) 1993-08-20 1994-08-08 Phosphonic diester derivative

Country Status (12)

Country Link
US (1) US5527786A (enExample)
EP (1) EP0666265B1 (enExample)
JP (1) JP3074332B2 (enExample)
KR (1) KR100305959B1 (enExample)
CN (1) CN1043897C (enExample)
AT (1) ATE189224T1 (enExample)
AU (1) AU678276B2 (enExample)
CA (1) CA2147375C (enExample)
DE (1) DE69422793T2 (enExample)
ES (1) ES2141830T3 (enExample)
TW (1) TW268008B (enExample)
WO (1) WO1995006051A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3533542B2 (ja) * 1994-03-08 2004-05-31 株式会社大塚製薬工場 ホスホン酸ジエステル誘導体
WO2010129138A2 (en) * 2009-04-27 2010-11-11 Limerick Biopharma Phosphorylated and phosphonated pyrone analogs for therapeutic treatment

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH471113A (de) * 1965-01-29 1969-04-15 Merck Ag E Verfahren zur Herstellung von wasserlöslichen Flavanoidderivaten
AU523040B2 (en) * 1978-05-15 1982-07-08 Kanebo Limited Calcium -antagonistic composition
US4434162A (en) * 1981-02-17 1984-02-28 Kanebo, Ltd. Phosphonic acid ester, pharmaceutical compositions containing the same and method of using the same
JPS5851958B2 (ja) * 1982-01-30 1983-11-19 カネボウ株式会社 新規１−（ベンゾチアゾ−ル−２−イル）−４−ジエトキシ−又はジイソプロポキシ−ホスフイニルベンゼン
US4870199A (en) * 1986-04-30 1989-09-26 Sandoz Pharm. Corp. Processes for the synthesis of diprotected R[R*,S*]-3,5-dihydroxy-6-oxohexanoate esters
JPH0651625B2 (ja) * 1986-12-29 1994-07-06 株式会社大塚製薬工場 高脂質血症治療剤
US4822780A (en) * 1987-07-08 1989-04-18 Otsuka Pharmaceutical Factory, Inc. Carboxamide compounds
AU606808B2 (en) * 1988-06-29 1991-02-14 Otsuka Pharmaceutical Factory, Inc. Arylcarboxamide substituted by alkylphosphonates, process for preparing the same and a pharmaceutical composition containing the same
JP2584336B2 (ja) * 1989-05-30 1997-02-26 株式会社大塚製薬工場 カルボン酸アミド誘導体
JP2549950B2 (ja) * 1991-01-24 1996-10-30 株式会社大塚製薬工場 イミダゾ［１，２−ａ］ピリジン誘導体、その製造方法及びその中間体としてのα−ハロケトン誘導体
JP2696150B2 (ja) * 1991-02-05 1998-01-14 株式会社大塚製薬工場 キノリン誘導体
JP2869608B2 (ja) * 1992-04-28 1999-03-10 株式会社大塚製薬工場 ホスホン酸ジエステル誘導体

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EUR.J.MED.CHEM., VOL.28., NO. 7-8, P539-546,(1993) *

Also Published As

Publication number Publication date
AU7276394A (en) 1995-03-21
TW268008B (enExample) 1996-01-11
JP3074332B2 (ja) 2000-08-07
CA2147375C (en) 2003-02-11
ATE189224T1 (de) 2000-02-15
EP0666265B1 (en) 2000-01-26
KR100305959B1 (ko) 2001-12-28
CN1043897C (zh) 1999-06-30
DE69422793D1 (de) 2000-03-02
CA2147375A1 (en) 1995-03-02
KR950704335A (ko) 1995-11-17
CN1114835A (zh) 1996-01-10
DE69422793T2 (de) 2000-06-21
EP0666265A1 (en) 1995-08-09
ES2141830T3 (es) 2000-04-01
WO1995006051A1 (en) 1995-03-02
US5527786A (en) 1996-06-18
EP0666265A4 (en) 1996-04-17

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Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired