KR100190412B1 - 히드록시 비타민 d화합물의 생물학적 제조방법 - Google Patents

히드록시 비타민 d화합물의 생물학적 제조방법 Download PDF

Info

Publication number
KR100190412B1
KR100190412B1 KR1019910009817A KR910009817A KR100190412B1 KR 100190412 B1 KR100190412 B1 KR 100190412B1 KR 1019910009817 A KR1019910009817 A KR 1019910009817A KR 910009817 A KR910009817 A KR 910009817A KR 100190412 B1 KR100190412 B1 KR 100190412B1
Authority
KR
South Korea
Prior art keywords
vitamin
compound
cyclodextrin
added
hydroxyvitamin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
KR1019910009817A
Other languages
English (en)
Korean (ko)
Other versions
KR920000934A (ko
Inventor
다고지 다께
기요시 기무라
가즈히꼬 오까무라
로꾸로 오까모또
사사끼조지
다까시 아다찌
사다후미 오무라
Original Assignee
스즈끼 다다오
메루샹 가부시키가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 스즈끼 다다오, 메루샹 가부시키가이샤 filed Critical 스즈끼 다다오
Publication of KR920000934A publication Critical patent/KR920000934A/ko
Application granted granted Critical
Publication of KR100190412B1 publication Critical patent/KR100190412B1/ko
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1019910009817A 1990-06-15 1991-06-14 히드록시 비타민 d화합물의 생물학적 제조방법 Expired - Lifetime KR100190412B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP15705490 1990-06-15
JP90-157054 1990-06-15
JP90-334283 1990-11-30
JP33428390A JP3201411B2 (ja) 1990-06-15 1990-11-30 ビタミンd類の生物学的製造方法
JP91-334283 1990-11-30

Publications (2)

Publication Number Publication Date
KR920000934A KR920000934A (ko) 1992-01-29
KR100190412B1 true KR100190412B1 (ko) 1999-06-01

Family

ID=26484632

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019910009817A Expired - Lifetime KR100190412B1 (ko) 1990-06-15 1991-06-14 히드록시 비타민 d화합물의 생물학적 제조방법

Country Status (9)

Country Link
US (1) US5474923A (enExample)
EP (1) EP0461921B1 (enExample)
JP (1) JP3201411B2 (enExample)
KR (1) KR100190412B1 (enExample)
AT (1) ATE127523T1 (enExample)
CA (1) CA2044550C (enExample)
DE (1) DE69112716T2 (enExample)
ES (1) ES2079573T3 (enExample)
TW (1) TW234147B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101131071B1 (ko) 2008-12-19 2012-03-30 일동제약주식회사 칼시트리올 또는 칼시페디올의 생산 촉진용 버퍼 조성물 및 이를 이용한 칼시트리올 또는 칼시페디올 생산방법

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3201411B2 (ja) * 1990-06-15 2001-08-20 メルシャン株式会社 ビタミンd類の生物学的製造方法
EP0653490A4 (en) * 1992-06-25 1997-01-08 Taisho Pharmaceutical Co Ltd VITAMIN D HYDROXYLASE GENE
JP3742435B2 (ja) 1995-08-28 2006-02-01 メルシャン株式会社 生物学的変換によるヒドロキシル化コレステロールの製造方法およびジヒドロキシコレステロール
AU3837100A (en) * 1999-04-14 2000-11-14 Chugai Seiyaku Kabushiki Kaisha Vitamin d derivatives and process for producing the same
KR20050044655A (ko) * 2001-12-03 2005-05-12 노바세아, 인크. 활성 비타민 d 화합물을 함유하는 약제학적 조성물
US7148211B2 (en) * 2002-09-18 2006-12-12 Genzyme Corporation Formulation for lipophilic agents
US20040058895A1 (en) * 2002-09-18 2004-03-25 Bone Care International, Inc. Multi-use vessels for vitamin D formulations
CN100540550C (zh) * 2004-01-29 2009-09-16 卫材R&D管理有限公司 大环内酯类化合物的稳定化方法
KR101366457B1 (ko) 2006-03-15 2014-03-12 니혼 마이크로바이오팜 가부시키가이샤 인덴 유도체의 제조 방법 및 그 제조 중간체

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4307025A (en) * 1981-02-17 1981-12-22 Wisconsin Alumni Research Foundation 1α, 25-dihydroxy-2β-fluorovitamin D3
JPH0717686B2 (ja) * 1986-08-08 1995-03-01 メルシャン株式会社 部分メチル化シクロデキストリン及びその製造方法
US4892821A (en) * 1987-07-08 1990-01-09 Taisho Pharmaceutical Co., Ltd. Method for preparing vitamin D compounds
JP2663294B2 (ja) * 1989-03-04 1997-10-15 メルシャン株式会社 ビタミンd類の製造方法
JP3201411B2 (ja) * 1990-06-15 2001-08-20 メルシャン株式会社 ビタミンd類の生物学的製造方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101131071B1 (ko) 2008-12-19 2012-03-30 일동제약주식회사 칼시트리올 또는 칼시페디올의 생산 촉진용 버퍼 조성물 및 이를 이용한 칼시트리올 또는 칼시페디올 생산방법

Also Published As

Publication number Publication date
ES2079573T3 (es) 1996-01-16
CA2044550C (en) 2000-09-26
CA2044550A1 (en) 1991-12-16
JPH04166090A (ja) 1992-06-11
US5474923A (en) 1995-12-12
ATE127523T1 (de) 1995-09-15
EP0461921B1 (en) 1995-09-06
EP0461921A2 (en) 1991-12-18
KR920000934A (ko) 1992-01-29
JP3201411B2 (ja) 2001-08-20
DE69112716D1 (de) 1995-10-12
TW234147B (enExample) 1994-11-11
DE69112716T2 (de) 1996-02-01
EP0461921A3 (en) 1992-05-20

Similar Documents

Publication Publication Date Title
JP3233476B2 (ja) Fo−1289物質およびその製造法
KR960004452B1 (ko) 비타민 d 화합물의 제조 방법
KR100190412B1 (ko) 히드록시 비타민 d화합물의 생물학적 제조방법
JP2993767B2 (ja) Fo−1289a物質およびその製造法
JPH08239385A (ja) Fo−1289物質およびその製造法
EP0425001B1 (en) Natural delta-lactones and process of the production thereof
JP2663294B2 (ja) ビタミンd類の製造方法
US5506140A (en) Bacillus strain for breaking down moenomycins
US5315038A (en) Microorganism for breaking down moenomycins, a process for the breakdown, and the use of the breakdown products
EP1172442A1 (en) Vitamin d derivatives and process for producing the same
JP3589685B2 (ja) ステロイド類の25位水酸化物の生物学的製造法
WO2000053792A1 (en) Substances wk-5344a and wk-5344b and process for producing the same
JPH07241197A (ja) 25−ヒドロキシビタミンd類の製造法
JP3742435B2 (ja) 生物学的変換によるヒドロキシル化コレステロールの製造方法およびジヒドロキシコレステロール
US6043050A (en) Biological process for producing steroids hydroxylated at the 25-position
JP2000295999A (ja) 1α,24−ジヒドロキシビタミンD3の生物学的製造方法
JP3434860B2 (ja) Fo−2546物質およびその製造法
JPH0464678B2 (enExample)
JP3735393B2 (ja) 1α−ヒドロキシビタミンD類の製造方法
JPWO1997008336A1 (ja) 生物学的変換によるヒドロキシル化コレステロールの製造方法およびジヒドロキシコレステロール
EP0916736B1 (en) Biological process for preparing 25-hydroxylated steroids
KR100234976B1 (ko) 세룰레닌 및 엘-메치오닌 유사체에 동시 내성을 갖는 아스퍼질 러스속 미생물 및 그를 이용한 메비놀린산의 제조방법
EP0216636A2 (en) Process for producing oganomycin E
JP4606523B2 (ja) ステロイド類の25位水酸化物の生物学的製造方法
US2872380A (en) Process for the production of 17-beta hydroxysteroids by neocosmospora

Legal Events

Date Code Title Description
PA0109 Patent application

Patent event code: PA01091R01D

Comment text: Patent Application

Patent event date: 19910614

PG1501 Laying open of application
N231 Notification of change of applicant
PN2301 Change of applicant

Patent event date: 19951017

Comment text: Notification of Change of Applicant

Patent event code: PN23011R01D

A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 19960416

Comment text: Request for Examination of Application

Patent event code: PA02011R01I

Patent event date: 19910614

Comment text: Patent Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 19980720

Patent event code: PE09021S01D

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

Patent event code: PE07011S01D

Comment text: Decision to Grant Registration

Patent event date: 19981215

GRNT Written decision to grant
PR0701 Registration of establishment

Comment text: Registration of Establishment

Patent event date: 19990120

Patent event code: PR07011E01D

PR1002 Payment of registration fee

Payment date: 19990121

End annual number: 3

Start annual number: 1

PG1601 Publication of registration
PR1001 Payment of annual fee

Payment date: 20011120

Start annual number: 4

End annual number: 4

PR1001 Payment of annual fee

Payment date: 20021114

Start annual number: 5

End annual number: 5

PR1001 Payment of annual fee

Payment date: 20031113

Start annual number: 6

End annual number: 6

PR1001 Payment of annual fee

Payment date: 20041115

Start annual number: 7

End annual number: 7

PR1001 Payment of annual fee

Payment date: 20051123

Start annual number: 8

End annual number: 8

PR1001 Payment of annual fee

Payment date: 20061120

Start annual number: 9

End annual number: 9

PR1001 Payment of annual fee

Payment date: 20071115

Start annual number: 10

End annual number: 10

PR1001 Payment of annual fee

Payment date: 20081118

Start annual number: 11

End annual number: 11

PR1001 Payment of annual fee

Payment date: 20091210

Start annual number: 12

End annual number: 12

FPAY Annual fee payment

Payment date: 20101122

Year of fee payment: 13

PR1001 Payment of annual fee

Payment date: 20101122

Start annual number: 13

End annual number: 13

EXPY Expiration of term
PC1801 Expiration of term

Termination date: 20121009

Termination category: Expiration of duration