|
US5714350A
(en)
|
1992-03-09 |
1998-02-03 |
Protein Design Labs, Inc. |
Increasing antibody affinity by altering glycosylation in the immunoglobulin variable region
|
|
US6005079A
(en)
|
1992-08-21 |
1999-12-21 |
Vrije Universiteit Brussels |
Immunoglobulins devoid of light chains
|
|
DE69334305D1
(de)
|
1992-08-21 |
2010-01-28 |
Univ Bruxelles |
Immunoglobuline ohne leichte Ketten
|
|
DK0698097T3
(da)
|
1993-04-29 |
2001-10-08 |
Unilever Nv |
Produktion af antistoffer eller (funktionaliserede) fragmenter deraf afledt af Camelidae-immunoglobuliner med tung kæde
|
|
US6013516A
(en)
|
1995-10-06 |
2000-01-11 |
The Salk Institute For Biological Studies |
Vector and method of use for nucleic acid delivery to non-dividing cells
|
|
AU3117697A
(en)
|
1996-05-06 |
1997-11-26 |
Uab Research Foundation, The |
Radiolabeled fusion toxins for cancer therapy
|
|
US5994136A
(en)
|
1997-12-12 |
1999-11-30 |
Cell Genesys, Inc. |
Method and means for producing high titer, safe, recombinant lentivirus vectors
|
|
US6995259B1
(en)
|
1998-10-23 |
2006-02-07 |
Sirna Therapeutics, Inc. |
Method for the chemical synthesis of oligonucleotides
|
|
US7723111B2
(en)
|
2001-03-09 |
2010-05-25 |
The United States Of America As Represented By The Department Of Health And Human Services |
Activated dual specificity lymphocytes and their methods of use
|
|
US7070995B2
(en)
|
2001-04-11 |
2006-07-04 |
City Of Hope |
CE7-specific redirected immune cells
|
|
US20090257994A1
(en)
|
2001-04-30 |
2009-10-15 |
City Of Hope |
Chimeric immunoreceptor useful in treating human cancers
|
|
EP1539233B1
(en)
|
2001-07-12 |
2011-04-27 |
FOOTE, Jefferson |
Super humanized antibodies
|
|
US7446190B2
(en)
|
2002-05-28 |
2008-11-04 |
Sloan-Kettering Institute For Cancer Research |
Nucleic acids encoding chimeric T cell receptors
|
|
AU2003265948B8
(en)
|
2002-09-06 |
2009-09-03 |
The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Immunotherapy with in vitro-selected antigen-specific lymphocytes after nonmyeloablative lymphodepleting chemotherapy
|
|
WO2004043401A2
(en)
|
2002-11-13 |
2004-05-27 |
Wackvom Limited |
Method of preparing anti-angiogenic drug from cartillage and chondrocytes and methods of use
|
|
US20130266551A1
(en)
|
2003-11-05 |
2013-10-10 |
St. Jude Children's Research Hospital, Inc. |
Chimeric receptors with 4-1bb stimulatory signaling domain
|
|
US20070036773A1
(en)
|
2005-08-09 |
2007-02-15 |
City Of Hope |
Generation and application of universal T cells for B-ALL
|
|
ES2382777T3
(es)
|
2006-05-03 |
2012-06-13 |
Government Of The United States Of America,As Represented By The Secretary, Department Of Health And Human Services |
Receptor de células T quimérico y materiales relacionados y métodos de uso
|
|
DE102006031054B4
(de)
|
2006-07-05 |
2010-08-05 |
Hänel & Co. |
Hochregal mit Lagergutanwahl
|
|
US9334330B2
(en)
|
2006-10-10 |
2016-05-10 |
Universite De Nantes |
Use of monoclonal antibodies specific to the O-acetylated form of GD2 ganglioside for the treatment of certain cancers
|
|
AU2008206442B2
(en)
|
2007-01-12 |
2012-10-18 |
Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
gp100-specific T cell receptors and related materials and methods of use
|
|
CA2967847C
(en)
|
2007-03-30 |
2023-08-01 |
Memorial Sloan-Kettering Cancer Center |
Constitutive expression of costimulatory ligands on adoptively transferred t lymphocytes
|
|
WO2008131445A1
(en)
|
2007-04-23 |
2008-10-30 |
The Board Of Regents, The University Of Texas System |
Device and method for transfecting cells for therapeutic use
|
|
US20110213288A1
(en)
|
2007-04-23 |
2011-09-01 |
The Board Of Regents, The University Of Texas System |
Device And Method For Transfecting Cells For Therapeutic Uses
|
|
EP2197910A2
(en)
|
2007-09-25 |
2010-06-23 |
The United States of America, as represented by the Secretary, Department of Health and Human Services |
Modified t cell receptors and related materials and methods
|
|
CN101335956B
(zh)
|
2008-08-05 |
2011-10-05 |
国民技术股份有限公司 |
借助误码率统计数据判断通信距离的系统和方法
|
|
EP2169837B1
(en)
|
2008-09-29 |
2013-01-30 |
Telefonaktiebolaget LM Ericsson (publ) |
Technique for suppressing noise in a transmitter device
|
|
US20100322909A1
(en)
|
2009-06-17 |
2010-12-23 |
The University Of Pittsburgh - Of The Commonwealth System Of Higher Education |
Th1-associated micrornas and their use for tumor immunotherapy
|
|
WO2011041093A1
(en)
|
2009-10-01 |
2011-04-07 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anti-vascular endothelial growth factor receptor-2 chimeric antigen receptors and use of same for the treatment of cancer
|
|
PT2495243T
(pt)
|
2009-10-27 |
2017-03-13 |
Delta-Fly Pharma Inc |
Novos derivados de 5-fluoruracilo
|
|
WO2011059836A2
(en)
|
2009-10-29 |
2011-05-19 |
Trustees Of Dartmouth College |
T cell receptor-deficient t cell compositions
|
|
US9273283B2
(en)
|
2009-10-29 |
2016-03-01 |
The Trustees Of Dartmouth College |
Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
|
|
US20110104128A1
(en)
|
2009-10-30 |
2011-05-05 |
The Board Of Regents, The University Of Texas System |
Device and Method for Transfecting Cells for Therapeutic Use
|
|
AU2010315243B2
(en)
|
2009-11-03 |
2016-08-25 |
City Of Hope |
Truncated epidermal growth factor receptor (EGFRt) for transduced T cell selection
|
|
US8956828B2
(en)
|
2009-11-10 |
2015-02-17 |
Sangamo Biosciences, Inc. |
Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleases
|
|
WO2011150420A1
(en)
|
2010-05-28 |
2011-12-01 |
Baylor College Of Medicine |
Modified gold nanoparticles for therapy
|
|
NZ702680A
(en)
|
2010-06-19 |
2016-07-29 |
Sloan Kettering Inst Cancer |
Anti-gd2 antibodies
|
|
CA2805442C
(en)
|
2010-07-21 |
2020-05-12 |
Sangamo Biosciences, Inc. |
Methods and compositions for modification of an hla locus
|
|
WO2012012695A2
(en)
|
2010-07-23 |
2012-01-26 |
Fred Hutchinson Cancer Research Center |
A method for the treatment of obesity
|
|
BR112013000873A2
(pt)
|
2010-07-28 |
2016-05-17 |
Synthes Gmbh |
sistema para fixação em osso; método para acoplamento do parafuso de osso e do acionador de parafuso de osso
|
|
WO2012136231A1
(en)
|
2010-09-08 |
2012-10-11 |
Chemotherapeutisches Forschungsinstitut Georg-Speyer-Haus |
Interleukin 15 as selectable marker for gene transfer in lymphocytes
|
|
PT3533802T
(pt)
|
2010-09-21 |
2021-06-21 |
Us Health |
Recetores de células t anti-ssx-2 e materiais e métodos de utilização relacionados
|
|
NZ609967A
(en)
|
2010-10-27 |
2015-04-24 |
Baylor College Medicine |
Chimeric cd27 receptors for redirecting t cells to cd70-positive malignancies
|
|
WO2012071420A1
(en)
|
2010-11-23 |
2012-05-31 |
The Trustees Of Columbia University In The City Of New York |
Enzyme combinations to reduce brain tissue swelling
|
|
MX347078B
(es)
|
2010-12-09 |
2017-04-10 |
Univ Pennsylvania |
Uso de celulas t modificadas por receptor de antigeno quimerico para tratar cancer.
|
|
AU2011343887B2
(en)
|
2010-12-14 |
2016-06-16 |
University Of Maryland, Baltimore |
Universal anti-tag chimeric antigen receptor-expressing T cells and methods of treating cancer
|
|
KR101796322B1
(ko)
|
2011-01-07 |
2017-12-01 |
삼성전자주식회사 |
항법 알고리즘을 이용한 위치 정보 검출 장치 및 방법
|
|
JP2014509841A
(ja)
|
2011-01-18 |
2014-04-24 |
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア |
癌を治療するための組成物および方法
|
|
AU2012214132B2
(en)
|
2011-02-11 |
2016-07-28 |
Memorial Sloan-Kettering Cancer Center |
HLA-restricted, peptide-specific antigen binding proteins
|
|
WO2012148552A2
(en)
|
2011-02-24 |
2012-11-01 |
The Research Foundation Of State University Of New York |
Rectifying electromagnetic nanosensors
|
|
NZ743310A
(en)
|
2011-03-23 |
2022-11-25 |
Fred Hutchinson Cancer Center |
Method and compositions for cellular immunotherapy
|
|
US20130071414A1
(en)
|
2011-04-27 |
2013-03-21 |
Gianpietro Dotti |
Engineered cd19-specific t lymphocytes that coexpress il-15 and an inducible caspase-9 based suicide gene for the treatment of b-cell malignancies
|
|
GB201108236D0
(en)
|
2011-05-17 |
2011-06-29 |
Ucl Business Plc |
Method
|
|
EP3549611B1
(en)
|
2011-07-29 |
2021-06-30 |
The Trustees of the University of Pennsylvania |
Switch costimulatory receptors
|
|
US9833476B2
(en)
|
2011-08-31 |
2017-12-05 |
The Trustees Of Dartmouth College |
NKP30 receptor targeted therapeutics
|
|
EP2755997B1
(en)
|
2011-09-15 |
2018-07-04 |
The United States of America, as represented by The Secretary, Department of Health and Human Services |
T cell receptors recognizing hla-a1- or hla-cw7-restricted mage
|
|
ES2795023T3
(es)
|
2011-09-16 |
2020-11-20 |
Baylor College Medicine |
Reconocimiento específico del microambiente tumoral mediante el uso de células NKT manipuladas
|
|
CN104126009B
(zh)
|
2011-10-07 |
2019-05-10 |
国立大学法人三重大学 |
嵌合抗原受体
|
|
ES2654060T3
(es)
|
2011-10-20 |
2018-02-12 |
The U.S.A. As Represented By The Secretary, Department Of Health And Human Services |
Receptores de antígenos quiméricos anti-CD22
|
|
US9688740B2
(en)
|
2011-10-26 |
2017-06-27 |
National Cancer Center |
Mutant CTLA4 gene transfected T cell and composition including same for anticancer immunotherapy
|
|
WO2013063419A2
(en)
|
2011-10-28 |
2013-05-02 |
The Trustees Of The University Of Pennsylvania |
A fully human, anti-mesothelin specific chimeric immune receptor for redirected mesothelin-expressing cell targeting
|
|
ES2861435T3
(es)
|
2011-11-03 |
2021-10-06 |
Univ Pennsylvania |
Composiciones específicas de B7-H4 aisladas y métodos de uso de las mismas
|
|
WO2013070468A1
(en)
|
2011-11-08 |
2013-05-16 |
The Trustees Of The University Of Pennsylvania |
Glypican-3-specific antibody and uses thereof
|
|
AU2012335073B2
(en)
|
2011-11-11 |
2017-08-17 |
Fred Hutchinson Cancer Center |
Cyclin A1-targeted T-cell immunotherapy for cancer
|
|
US10391126B2
(en)
|
2011-11-18 |
2019-08-27 |
Board Of Regents, The University Of Texas System |
CAR+ T cells genetically modified to eliminate expression of T-cell receptor and/or HLA
|
|
US8772058B2
(en)
|
2012-02-02 |
2014-07-08 |
Harris Corporation |
Method for making a redistributed wafer using transferrable redistribution layers
|
|
US9328228B2
(en)
|
2012-02-13 |
2016-05-03 |
Denka Company Limited |
Chloroprene rubber composition and adhesive composition using said chloroprene rubber composition
|
|
WO2013126712A1
(en)
|
2012-02-22 |
2013-08-29 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for generating a persisting population of t cells useful for the treatment of cancer
|
|
IN2014DN07414A
(es)
|
2012-02-22 |
2015-04-24 |
Univ Pennsylvania |
|
|
EA201491573A1
(ru)
|
2012-02-22 |
2015-03-31 |
Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания |
Применение передающего сигнал домена cd2 в химерных антигенспецифических рецепторах второго поколения
|
|
RU2766608C2
(ru)
|
2012-04-11 |
2022-03-15 |
Дзе Юнайтед Стейтс Оф Америка, Эз Репрезентед Бай Дзе Секретари, Департмент Оф Хелс Энд Хьюман Сёрвисез |
Химерные антигенные рецепторы, нацеленные на антиген созревания b-клеток
|
|
GB201206559D0
(en)
|
2012-04-13 |
2012-05-30 |
Ucl Business Plc |
Polypeptide
|
|
US20130280220A1
(en)
|
2012-04-20 |
2013-10-24 |
Nabil Ahmed |
Chimeric antigen receptor for bispecific activation and targeting of t lymphocytes
|
|
JP6389166B2
(ja)
|
2012-05-07 |
2018-09-12 |
トラスティーズ・オブ・ダートマス・カレッジ |
抗ｂ７−ｈ６抗体、融合タンパク質、及びこれらを使用する方法
|
|
US20150017136A1
(en)
|
2013-07-15 |
2015-01-15 |
Cellectis |
Methods for engineering allogeneic and highly active t cell for immunotherapy
|
|
DK2855667T3
(da)
|
2012-05-25 |
2023-10-30 |
Cellectis |
Fremgangsmåder til manipulation af allogeniske og immunosuppressiv-resistante T-celler til immunterapi
|
|
EP2872526B1
(en)
|
2012-07-13 |
2020-04-01 |
The Trustees of the University of Pennsylvania |
Enhancing activity of car t cells by co-introducing a bispecific antibody
|
|
MX370495B
(es)
|
2012-07-13 |
2019-12-13 |
Univ Pennsylvania |
Métodos para evaluar la conveniencia de células t transducidas para administración.
|
|
JP5822798B2
(ja)
|
2012-08-08 |
2015-11-24 |
三菱電機株式会社 |
断熱箱体及びこの断熱箱体を備えた冷蔵庫
|
|
US20140065629A1
(en)
|
2012-08-29 |
2014-03-06 |
Israel Barken |
Methods of treating diseases
|
|
WO2014037422A1
(en)
|
2012-09-04 |
2014-03-13 |
Inven2 As |
Selective and controlled expansion of educated nk cells
|
|
WO2014039513A2
(en)
|
2012-09-04 |
2014-03-13 |
The Trustees Of The University Of Pennsylvania |
Inhibition of diacylglycerol kinase to augment adoptive t cell transfer
|
|
ES2586331T3
(es)
|
2012-09-05 |
2016-10-13 |
Institut National Des Sciences Appliquées De Lyon |
Procedimiento de fabricación de un transistor de efecto de campo de unión JFET
|
|
WO2014055442A2
(en)
|
2012-10-01 |
2014-04-10 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for targeting stromal cells for the treatment of cancer
|
|
WO2014055771A1
(en)
|
2012-10-05 |
2014-04-10 |
The Trustees Of The University Of Pennsylvania |
Human alpha-folate receptor chimeric antigen receptor
|
|
EP2906684B8
(en)
|
2012-10-10 |
2020-09-02 |
Sangamo Therapeutics, Inc. |
T cell modifying compounds and uses thereof
|
|
WO2014059248A1
(en)
|
2012-10-12 |
2014-04-17 |
Philadelphia Health & Education Corporation D/B/A/ Drexel |
Mir-155 enhancement of cd8+ t cell immunity
|
|
JO3529B1
(ar)
|
2013-02-08 |
2020-07-05 |
Amgen Res Munich Gmbh |
مضاد التصاق خلايا الدم البيض من أجل التخفيف من الاثار السلبية الممكنة الناتجة عن مجالات ارتباط cd3- المحدد
|
|
TW201446794A
(zh)
|
2013-02-20 |
2014-12-16 |
Novartis Ag |
利用抗－ｃｄ１２３嵌合抗原受體工程化ｔ細胞之初級人類白血病有效靶向
|
|
ES2760023T3
(es)
|
2013-02-20 |
2020-05-12 |
Univ Pennsylvania |
Tratamiento del cáncer utilizando receptor de antígeno quimérico anti-EGFRvIII humanizado
|
|
US9499855B2
(en)
|
2013-03-14 |
2016-11-22 |
Elwha Llc |
Compositions, methods, and computer systems related to making and administering modified T cells
|
|
US20140274801A1
(en)
|
2013-03-14 |
2014-09-18 |
Elwha Llc |
Compositions, methods, and computer systems related to making and administering modified t cells
|
|
US9587237B2
(en)
|
2013-03-14 |
2017-03-07 |
Elwha Llc |
Compositions, methods, and computer systems related to making and administering modified T cells
|
|
US9446105B2
(en)
|
2013-03-15 |
2016-09-20 |
The Trustees Of The University Of Pennsylvania |
Chimeric antigen receptor specific for folate receptor β
|
|
US9657105B2
(en)
|
2013-03-15 |
2017-05-23 |
City Of Hope |
CD123-specific chimeric antigen receptor redirected T cells and methods of their use
|
|
EP3623380A1
(en)
|
2013-03-15 |
2020-03-18 |
Michael C. Milone |
Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
|
|
US9393268B2
(en)
|
2013-03-15 |
2016-07-19 |
Thomas Jefferson University |
Cell-based anti-cancer compositions with reduced toxicity and methods of making and using the same
|
|
UY35468A
(es)
|
2013-03-16 |
2014-10-31 |
Novartis Ag |
Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19
|
|
AU2014255733B2
(en)
|
2013-04-18 |
2019-05-16 |
Tilt Biotherapeutics Oy |
Enhanced adoptive cell therapy
|
|
WO2014201378A1
(en)
|
2013-06-13 |
2014-12-18 |
Massachusetts Institute Of Technology |
Synergistic tumor treatment with extended-pk il -2 and adoptive cell therapy
|
|
WO2014201319A1
(en)
|
2013-06-14 |
2014-12-18 |
The University Of Houston System |
Targeting tumor neovasculature with modified chimeric antigen receptors
|
|
DE102013212604A1
(de)
|
2013-06-28 |
2014-12-31 |
Robert Bosch Gmbh |
Bearbeitungswerkzeug
|
|
WO2015010096A1
(en)
|
2013-07-18 |
2015-01-22 |
Baylor College Of Medicine |
Method of enhancing potency of immune cells
|
|
NO335489B1
(no)
|
2013-08-27 |
2014-12-22 |
Langåker John Magne |
Multifunksjons varmepumpe
|
|
CN105594162B
(zh)
|
2013-08-30 |
2019-02-05 |
豪倍公司 |
WiFi危险区VoIP寻呼电话及系统
|
|
WO2015038684A1
(en)
|
2013-09-10 |
2015-03-19 |
Polyera Corporation |
Attachable article with signaling, split display and messaging features
|
|
HUE037286T2
(hu)
|
2014-02-05 |
2018-08-28 |
Elcogen Oy |
Összeszerelési eljárás és elrendezés cellarendszerhez
|
|
WO2015141347A1
(ja)
|
2014-03-17 |
2015-09-24 |
ナミックス株式会社 |
樹脂組成物
|
|
TWI805109B
(zh)
|
2014-08-28 |
2023-06-11 |
美商奇諾治療有限公司 |
對cd19具專一性之抗體及嵌合抗原受體
|
|
ES2879612T3
(es)
|
2014-10-20 |
2021-11-22 |
Juno Therapeutics Inc |
Métodos y composiciones para dosificación en terapia celular adoptiva
|
|
MA41346A
(fr)
|
2015-01-12 |
2017-11-21 |
Juno Therapeutics Inc |
Eléments régulateurs post-transcriptionnels d'hépatite modifiée
|
|
EP3760644A1
(en)
|
2015-01-16 |
2021-01-06 |
Juno Therapeutics, Inc. |
Antibodies and chimeric antigen receptors specific for ror1
|
|
JP7114457B2
(ja)
|
2015-04-17 |
2022-08-08 |
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア |
キメラ抗原受容体発現細胞の有効性および増殖を改善するための方法
|
|
CA2992551A1
(en)
|
2015-07-21 |
2017-01-26 |
Novartis Ag |
Methods for improving the efficacy and expansion of immune cells
|