JPWO2021167011A1 - - Google Patents
Info
- Publication number
- JPWO2021167011A1 JPWO2021167011A1 JP2022501977A JP2022501977A JPWO2021167011A1 JP WO2021167011 A1 JPWO2021167011 A1 JP WO2021167011A1 JP 2022501977 A JP2022501977 A JP 2022501977A JP 2022501977 A JP2022501977 A JP 2022501977A JP WO2021167011 A1 JPWO2021167011 A1 JP WO2021167011A1
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
- C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q3/00—Condition responsive control processes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01027—L-Lactate dehydrogenase (1.1.1.27)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2521/00—Reaction characterised by the enzymatic activity
- C12Q2521/50—Other enzymatic activities
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/05—Oxidoreductases acting on the CH-OH group of donors (1.1) with a quinone or similar compound as acceptor (1.1.5)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/902—Oxidoreductases (1.)
- G01N2333/904—Oxidoreductases (1.) acting on CHOH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Plant Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025119817A JP2025160264A (ja) | 2020-02-21 | 2025-07-16 | 検体の状態を評価するためのデバイス、それを含むシステム、検体の状態を評価する方法及びそれに用いる乳酸デヒドロゲナーゼ |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020028722 | 2020-02-21 | ||
| JP2020028722 | 2020-02-21 | ||
| JP2020106467 | 2020-06-19 | ||
| JP2020106467 | 2020-06-19 | ||
| PCT/JP2021/006153 WO2021167011A1 (ja) | 2020-02-21 | 2021-02-18 | 検体の状態を評価するためのデバイス、それを含むシステム、検体の状態を評価する方法及びそれに用いる乳酸デヒドロゲナーゼ |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025119817A Division JP2025160264A (ja) | 2020-02-21 | 2025-07-16 | 検体の状態を評価するためのデバイス、それを含むシステム、検体の状態を評価する方法及びそれに用いる乳酸デヒドロゲナーゼ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2021167011A1 true JPWO2021167011A1 (https=) | 2021-08-26 |
| JPWO2021167011A5 JPWO2021167011A5 (https=) | 2024-01-26 |
| JP7714520B2 JP7714520B2 (ja) | 2025-07-29 |
Family
ID=77392166
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022501977A Active JP7714520B2 (ja) | 2020-02-21 | 2021-02-18 | 検体の状態を評価するためのデバイス、それを含むシステム、検体の状態を評価する方法及びそれに用いる乳酸デヒドロゲナーゼ |
| JP2025119817A Pending JP2025160264A (ja) | 2020-02-21 | 2025-07-16 | 検体の状態を評価するためのデバイス、それを含むシステム、検体の状態を評価する方法及びそれに用いる乳酸デヒドロゲナーゼ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025119817A Pending JP2025160264A (ja) | 2020-02-21 | 2025-07-16 | 検体の状態を評価するためのデバイス、それを含むシステム、検体の状態を評価する方法及びそれに用いる乳酸デヒドロゲナーゼ |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20230213499A1 (https=) |
| EP (1) | EP4108678A4 (https=) |
| JP (2) | JP7714520B2 (https=) |
| KR (1) | KR20220143091A (https=) |
| WO (1) | WO2021167011A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4223884A4 (en) * | 2020-09-29 | 2024-12-11 | Kikkoman Corporation | METHOD FOR IMPROVING THE STABILITY OF A COMPOSITION CONTAINING FLAVIN-DEPENDENT LACTATE DEHYDROGENASE |
| WO2022258733A1 (en) | 2021-06-09 | 2022-12-15 | Directsens Gmbh | Novel production method of flavocytochrome b2 |
| US20240401002A1 (en) * | 2021-08-03 | 2024-12-05 | Kikkoman Corporation | Novel flavin-dependent lactate dehydrogenase and method for improving stability of lactate dehydrogenase |
| TWI814233B (zh) * | 2022-01-28 | 2023-09-01 | 住華科技股份有限公司 | 硼酸檢測試片及硼酸檢測方法 |
Citations (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58175498A (ja) * | 1982-03-26 | 1983-10-14 | メルク・パテント・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング | 液体中の物質の測定用試験系および試験方法 |
| JPS61159164A (ja) * | 1984-09-21 | 1986-07-18 | ジヨナサン・エル・キ−ル | ミクロ化学発光アツセイシステム |
| JPH04346796A (ja) * | 1991-05-21 | 1992-12-02 | Asahi Chem Ind Co Ltd | 乳酸またはピルビン酸の高感度定量法および定量用組成物 |
| JPH06153995A (ja) * | 1992-11-26 | 1994-06-03 | Sekisui Chem Co Ltd | 細菌ホロルシフェラーゼを用いた測定法 |
| JPH08327581A (ja) * | 1995-05-24 | 1996-12-13 | Co Ri Al S C P A | 栄養的に注目される有機物質中の乳酸の測定方法およびこの方法を実施するためのバイオセンサー |
| JPH10513063A (ja) * | 1995-11-22 | 1998-12-15 | ベーリンガー マンハイム ゲーエムベーハー | 安定化された補酵素溶液、並びにアルカリ性環境下でのデヒドロゲナーゼ及び基質の測定のためのその使用 |
| JP2009517045A (ja) * | 2005-11-23 | 2009-04-30 | ネイチャーワークス・エル・エル・シー | Ｌ−又はｄ−ラクタート：フェリチトクロームｃ酸化還元酵素遺伝子が機能しない乳酸産生酵母 |
| WO2012068236A2 (en) * | 2010-11-16 | 2012-05-24 | Dyadic International (Usa) Inc. | Novel fungal oxidoreductases |
| JP2013066466A (ja) * | 2011-09-20 | 2013-04-18 | F Hoffmann La Roche Ag | 安定性が高められた変異型乳酸オキシダーゼ、ならびにそれに関連する生成物、方法および使用 |
| JP2014501502A (ja) * | 2010-11-22 | 2014-01-23 | キンバリー クラーク ワールドワイド インコーポレイテッド | 良好な健康状態のバイオマーカを検出するための膣用インジケータ |
| WO2015017721A1 (en) * | 2013-07-31 | 2015-02-05 | Novozymes A/S | 3-hydroxypropionic acid production by recombinant yeasts expressing an insect aspartate 1-decarboxylase |
| WO2016138303A1 (en) * | 2015-02-27 | 2016-09-01 | Novozymes A/S | Mutant host cells for the production of 3-hydroxypropionic acid |
| WO2018053230A1 (en) * | 2016-09-16 | 2018-03-22 | Cargill, Incorporated | Genetically modified lactate-consuming yeasts and fermentation processes using such genetically modified yeasts |
| WO2022071417A1 (ja) * | 2020-09-29 | 2022-04-07 | キッコーマン株式会社 | フラビン依存性乳酸デヒドロゲナーゼを含む組成物の安定性を向上する方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5593689B2 (ja) | 2009-12-09 | 2014-09-24 | 東洋紡株式会社 | 乳酸オキシダーゼ組成物 |
| US10619183B2 (en) | 2013-08-09 | 2020-04-14 | Kikkoman Corporation | Modified amadoriase and method for producing the same, agent for improving surfactant resistance of amadoriase and composition for measuring HbA1c using the same |
| WO2016205378A1 (en) | 2015-06-15 | 2016-12-22 | Abbott Diabetes Care Inc. | Stabilized lactate responsive enzymes, electrodes and sensors, and methods for making and using the same |
| JP6703893B2 (ja) | 2015-12-01 | 2020-06-03 | パナソニック インテレクチュアル プロパティ コーポレーション オブ アメリカＰａｎａｓｏｎｉｃ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｃｏｒｐｏｒａｔｉｏｎ ｏｆ Ａｍｅｒｉｃａ | 体調推定装置、及び、体調推定システム |
| WO2017163521A1 (ja) | 2016-03-23 | 2017-09-28 | 日本電気株式会社 | 情報処理装置、その制御方法ならびにその制御プログラム |
| WO2019006413A1 (en) * | 2017-06-30 | 2019-01-03 | Abbott Diabetes Care | METHOD AND APPARATUS FOR ANALYTE DETECTION USING ELECTROCHEMICAL BIOSENSOR |
| JP6941379B2 (ja) | 2017-11-28 | 2021-09-29 | 株式会社ユピテル | 電子機器およびプログラム |
-
2021
- 2021-02-18 US US17/801,033 patent/US20230213499A1/en active Pending
- 2021-02-18 EP EP21756429.3A patent/EP4108678A4/en active Pending
- 2021-02-18 JP JP2022501977A patent/JP7714520B2/ja active Active
- 2021-02-18 WO PCT/JP2021/006153 patent/WO2021167011A1/ja not_active Ceased
- 2021-02-18 KR KR1020227032145A patent/KR20220143091A/ko active Pending
-
2025
- 2025-07-16 JP JP2025119817A patent/JP2025160264A/ja active Pending
Patent Citations (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58175498A (ja) * | 1982-03-26 | 1983-10-14 | メルク・パテント・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング | 液体中の物質の測定用試験系および試験方法 |
| JPS61159164A (ja) * | 1984-09-21 | 1986-07-18 | ジヨナサン・エル・キ−ル | ミクロ化学発光アツセイシステム |
| JPH04346796A (ja) * | 1991-05-21 | 1992-12-02 | Asahi Chem Ind Co Ltd | 乳酸またはピルビン酸の高感度定量法および定量用組成物 |
| JPH06153995A (ja) * | 1992-11-26 | 1994-06-03 | Sekisui Chem Co Ltd | 細菌ホロルシフェラーゼを用いた測定法 |
| JPH08327581A (ja) * | 1995-05-24 | 1996-12-13 | Co Ri Al S C P A | 栄養的に注目される有機物質中の乳酸の測定方法およびこの方法を実施するためのバイオセンサー |
| JPH10513063A (ja) * | 1995-11-22 | 1998-12-15 | ベーリンガー マンハイム ゲーエムベーハー | 安定化された補酵素溶液、並びにアルカリ性環境下でのデヒドロゲナーゼ及び基質の測定のためのその使用 |
| JP2009517045A (ja) * | 2005-11-23 | 2009-04-30 | ネイチャーワークス・エル・エル・シー | Ｌ−又はｄ−ラクタート：フェリチトクロームｃ酸化還元酵素遺伝子が機能しない乳酸産生酵母 |
| WO2012068236A2 (en) * | 2010-11-16 | 2012-05-24 | Dyadic International (Usa) Inc. | Novel fungal oxidoreductases |
| JP2014501502A (ja) * | 2010-11-22 | 2014-01-23 | キンバリー クラーク ワールドワイド インコーポレイテッド | 良好な健康状態のバイオマーカを検出するための膣用インジケータ |
| JP2013066466A (ja) * | 2011-09-20 | 2013-04-18 | F Hoffmann La Roche Ag | 安定性が高められた変異型乳酸オキシダーゼ、ならびにそれに関連する生成物、方法および使用 |
| WO2015017721A1 (en) * | 2013-07-31 | 2015-02-05 | Novozymes A/S | 3-hydroxypropionic acid production by recombinant yeasts expressing an insect aspartate 1-decarboxylase |
| WO2016138303A1 (en) * | 2015-02-27 | 2016-09-01 | Novozymes A/S | Mutant host cells for the production of 3-hydroxypropionic acid |
| WO2018053230A1 (en) * | 2016-09-16 | 2018-03-22 | Cargill, Incorporated | Genetically modified lactate-consuming yeasts and fermentation processes using such genetically modified yeasts |
| WO2022071417A1 (ja) * | 2020-09-29 | 2022-04-07 | キッコーマン株式会社 | フラビン依存性乳酸デヒドロゲナーゼを含む組成物の安定性を向上する方法 |
Non-Patent Citations (9)
| Title |
|---|
| "A0A4T0X365, July 31, 2019 uploaded, [retrieved Apr 16, 2021], Definition: Uncharacterized protein", DATABASE UNIPROT[ONLINE], JPN6021015338, ISSN: 0005462393 * |
| D W REED: "The Archaeoglobus fulgidus D-lactate dehydrogenase is a Zn(2+) flavoprotein", J BACTERIOL, vol. 181(24), JPN6024046758, December 1999 (1999-12-01), pages 7580 - 7587, ISSN: 0005618952 * |
| RALF OSTENDORP: "Extremely thermostable L(+)-lactate dehydrogenase from Thermotoga maritima: Cloning, characterizatio", PROFEIN SCIENCE, vol. 5, JPN6024046759, 1996, pages 862 - 873, ISSN: 0005618953 * |
| ROBERT RILEY: "Comparative genomics of biotechnologically important yeasts", PNAS, vol. 113, no. 5, JPN6024046763, 30 August 2016 (2016-08-30), pages 9882 - 9887, ISSN: 0005618957 * |
| UPI0007F33D28 | UNIPARC | UNIPROT, JPN6024046757, 23 September 2016 (2016-09-23), ISSN: 0005462395 * |
| UPI001135A80B | UNIPARC | UNIPROT, JPN6024046756, 31 July 2019 (2019-07-31), ISSN: 0005462394 * |
| 赤沼哲史: "極限環境で働くタンパク質の特徴と利用 好熱菌のタンパク質はなぜ熱に強いか", 生化学, vol. 81, no. 12, JPN6024046762, 25 December 2009 (2009-12-25), pages 81 - 12, ISSN: 0005618956 * |
| 鈴木遼太: "フラビン依存性乳酸デヒドロゲナーゼの電子伝達機構の解析", 日本農芸化学会大会講演要旨集, vol. 2023, JPN6024046760, 5 March 2023 (2023-03-05), pages 2 - 05, ISSN: 0005618954 * |
| 鈴木遼太: "乳酸センサ用フラビン依存性乳酸デヒドロゲナーゼの探索および特性評価", 日本農芸化学会大会講演要旨集, vol. 2022, JPN6024046761, 5 March 2022 (2022-03-05), pages 4 - 05, ISSN: 0005618955 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP4108678A1 (en) | 2022-12-28 |
| EP4108678A4 (en) | 2024-03-27 |
| JP7714520B2 (ja) | 2025-07-29 |
| WO2021167011A1 (ja) | 2021-08-26 |
| KR20220143091A (ko) | 2022-10-24 |
| JP2025160264A (ja) | 2025-10-22 |
| US20230213499A1 (en) | 2023-07-06 |
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