JPWO2023013498A1 - - Google Patents
Info
- Publication number
- JPWO2023013498A1 JPWO2023013498A1 JP2023540286A JP2023540286A JPWO2023013498A1 JP WO2023013498 A1 JPWO2023013498 A1 JP WO2023013498A1 JP 2023540286 A JP2023540286 A JP 2023540286A JP 2023540286 A JP2023540286 A JP 2023540286A JP WO2023013498 A1 JPWO2023013498 A1 JP WO2023013498A1
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/02—Oxidoreductases acting on the CH-OH group of donors (1.1) with a cytochrome as acceptor (1.1.2)
- C12Y101/02003—L-Lactate dehydrogenase (cytochrome) (1.1.2.3)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01027—L-Lactate dehydrogenase (1.1.1.27)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Cell Biology (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021127638 | 2021-08-03 | ||
| PCT/JP2022/028959 WO2023013498A1 (ja) | 2021-08-03 | 2022-07-27 | 新規フラビン依存性乳酸デヒドロゲナーゼ及び乳酸デヒドロゲナーゼの安定性を向上させる方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2023013498A1 true JPWO2023013498A1 (https=) | 2023-02-09 |
| JPWO2023013498A5 JPWO2023013498A5 (https=) | 2025-09-09 |
Family
ID=85154538
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023540286A Pending JPWO2023013498A1 (https=) | 2021-08-03 | 2022-07-27 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20240401002A1 (https=) |
| EP (1) | EP4382608A4 (https=) |
| JP (1) | JPWO2023013498A1 (https=) |
| WO (1) | WO2023013498A1 (https=) |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4884733B2 (ja) * | 2005-09-15 | 2012-02-29 | オリエンタル酵母工業株式会社 | D−乳酸脱水素酵素 |
| WO2016205378A1 (en) | 2015-06-15 | 2016-12-22 | Abbott Diabetes Care Inc. | Stabilized lactate responsive enzymes, electrodes and sensors, and methods for making and using the same |
| CN109906270A (zh) * | 2016-09-16 | 2019-06-18 | 嘉吉公司 | 经遗传修饰的乳酸消耗酵母以及使用此类经遗传修饰的酵母的发酵工艺 |
| JP2021078427A (ja) * | 2019-11-19 | 2021-05-27 | アイシン精機株式会社 | D−乳酸脱水素酵素変異体、d−乳酸脱水素酵素変異体を備えたバイオ燃料電池、及び、バイオセンサ |
| US20230213499A1 (en) * | 2020-02-21 | 2023-07-06 | Kikkoman Corporation | Device for evaluating state of sample, system containing same, method for evaluating state of sample and lactate dehydrogenase used therefor |
| CN112813043A (zh) * | 2021-02-23 | 2021-05-18 | 江南大学 | 一种酶活及稳定性提高的l-乳酸脱氢酶突变体及其应用 |
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2022
- 2022-07-27 US US18/294,648 patent/US20240401002A1/en active Pending
- 2022-07-27 WO PCT/JP2022/028959 patent/WO2023013498A1/ja not_active Ceased
- 2022-07-27 EP EP22852921.0A patent/EP4382608A4/en active Pending
- 2022-07-27 JP JP2023540286A patent/JPWO2023013498A1/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP4382608A1 (en) | 2024-06-12 |
| US20240401002A1 (en) | 2024-12-05 |
| WO2023013498A1 (ja) | 2023-02-09 |
| EP4382608A4 (en) | 2025-07-16 |
Similar Documents
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20250722 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20250901 |