JPWO2021132546A5 - - Google Patents

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JPWO2021132546A5
JPWO2021132546A5 JP2021567657A JP2021567657A JPWO2021132546A5 JP WO2021132546 A5 JPWO2021132546 A5 JP WO2021132546A5 JP 2021567657 A JP2021567657 A JP 2021567657A JP 2021567657 A JP2021567657 A JP 2021567657A JP WO2021132546 A5 JPWO2021132546 A5 JP WO2021132546A5
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Japan
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trna
character
composition according
codon
anticodon
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JP2021567657A
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Japanese (ja)
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JPWO2021132546A1 (https=
JP7744244B2 (ja
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Priority claimed from PCT/JP2019/051241 external-priority patent/WO2020138336A1/ja
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Priority claimed from PCT/JP2020/048652 external-priority patent/WO2021132546A1/ja
Publication of JPWO2021132546A1 publication Critical patent/JPWO2021132546A1/ja
Publication of JPWO2021132546A5 publication Critical patent/JPWO2021132546A5/ja
Priority to JP2025151312A priority Critical patent/JP2025172162A/ja
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Publication of JP7744244B2 publication Critical patent/JP7744244B2/ja
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JP2021567657A 2019-12-26 2020-12-25 翻訳用組成物及びペプチドの製造方法 Active JP7744244B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025151312A JP2025172162A (ja) 2019-12-26 2025-09-11 翻訳用組成物及びペプチドの製造方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JPPCT/JP2019/051241 2019-12-26
PCT/JP2019/051241 WO2020138336A1 (ja) 2018-12-26 2019-12-26 コドン拡張のための変異tRNA
JP2020109292 2020-06-25
JP2020109292 2020-06-25
PCT/JP2020/048652 WO2021132546A1 (ja) 2019-12-26 2020-12-25 翻訳用組成物及びペプチドの製造方法

Related Child Applications (1)

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JP2025151312A Division JP2025172162A (ja) 2019-12-26 2025-09-11 翻訳用組成物及びペプチドの製造方法

Publications (3)

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JPWO2021132546A1 JPWO2021132546A1 (https=) 2021-07-01
JPWO2021132546A5 true JPWO2021132546A5 (https=) 2023-12-08
JP7744244B2 JP7744244B2 (ja) 2025-09-25

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ID=76573318

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JP2021567657A Active JP7744244B2 (ja) 2019-12-26 2020-12-25 翻訳用組成物及びペプチドの製造方法
JP2025151312A Pending JP2025172162A (ja) 2019-12-26 2025-09-11 翻訳用組成物及びペプチドの製造方法

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Country Link
US (1) US20230108274A1 (https=)
EP (1) EP4026906A4 (https=)
JP (2) JP7744244B2 (https=)
KR (1) KR20220121831A (https=)
CN (1) CN114641569A (https=)
WO (1) WO2021132546A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202446781A (zh) 2011-12-28 2024-12-01 日商中外製藥股份有限公司 胜肽化合物之製造方法
EP4166664A1 (en) 2015-03-13 2023-04-19 Chugai Seiyaku Kabushiki Kaisha Modified aminoacyl-trna synthetase and use thereof
JP7187323B2 (ja) 2017-01-31 2022-12-12 中外製薬株式会社 無細胞翻訳系におけるペプチドの合成方法
KR20250007021A (ko) 2017-06-09 2025-01-13 추가이 세이야쿠 가부시키가이샤 N-치환 아미노산을 포함하는 펩타이드의 합성 방법
EP3878836B1 (en) 2018-11-07 2025-07-23 Chugai Seiyaku Kabushiki Kaisha O-substituted serine derivative production method
EP3939962A4 (en) 2019-03-15 2022-12-28 Chugai Seiyaku Kabushiki Kaisha PROCESS FOR PREPARING AN AROMATIC AMINO ACID DERIVATIVE
BR112022007535A2 (pt) 2019-11-07 2022-07-12 Chugai Pharmaceutical Co Ltd Composto peptídico cíclico tendo ação inibitória de kras
JP7823181B2 (ja) 2022-05-06 2026-03-03 中外製薬株式会社 Hrasおよびnrasに対して選択的なkras阻害作用を有する環状化合物

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006500927A (ja) * 2002-09-13 2006-01-12 ザ・ユニバーシティ・オブ・クイーンズランド コドン翻訳効率に基づく遺伝子発現系
WO2006135096A1 (ja) 2005-06-14 2006-12-21 Gifu University 部位特異的にタンパク質にチロシンアナログを導入する方法
WO2007061136A1 (ja) 2005-11-24 2007-05-31 Riken 非天然型アミノ酸を組み込んだタンパク質の製造方法
WO2007066627A1 (ja) 2005-12-06 2007-06-14 The University Of Tokyo 多目的アシル化触媒とその用途
AU2007224019A1 (en) 2006-03-03 2007-09-13 California Institute Of Technology Site-specific incorporation of amino acids into molecules
WO2008001947A1 (en) 2006-06-28 2008-01-03 Riken MUTANT SepRS, AND METHOD FOR SITE-SPECIFIC INTRODUCTION OF PHOSPHOSERINE INTO PROTEIN BY USING THE SAME
US20120077224A1 (en) 2009-06-05 2012-03-29 The Salk Institute For Biological Studies unnatural amino acid incorporation in eukaryotic cells
JP5725467B2 (ja) 2010-08-27 2015-05-27 国立大学法人 東京大学 新規人工翻訳合成系
JP5818237B2 (ja) 2010-09-09 2015-11-18 国立大学法人 東京大学 N−メチルアミノ酸およびその他の特殊アミノ酸を含む特殊ペプチド化合物ライブラリーの翻訳構築と活性種探索法
EP2647720B1 (en) 2010-12-03 2019-06-19 The University of Tokyo Peptide library production method, peptide library, and screening method
TW202446781A (zh) * 2011-12-28 2024-12-01 日商中外製藥股份有限公司 胜肽化合物之製造方法
JP6440055B2 (ja) * 2013-05-10 2018-12-19 国立大学法人 東京大学 ペプチドライブラリの製造方法、ペプチドライブラリ、及びスクリーニング方法
JP6754997B2 (ja) 2013-08-26 2020-09-16 国立大学法人 東京大学 大環状ペプチド、その製造方法、及び大環状ペプチドライブラリを用いるスクリーニング方法
WO2015120287A2 (en) 2014-02-06 2015-08-13 Yale University Compositions and methods of use thereof for making polypeptides with many instances of nonstandard amino acids
JP6814533B2 (ja) * 2015-09-29 2021-01-20 村上 裕 タンパク質を製造するための翻訳系、及びタンパク質の製造方法
WO2018052002A1 (ja) 2016-09-13 2018-03-22 第一三共株式会社 Thrombospondin 1結合ペプチド
JP7187323B2 (ja) 2017-01-31 2022-12-12 中外製薬株式会社 無細胞翻訳系におけるペプチドの合成方法
CN110869544B (zh) 2017-06-09 2024-03-08 中外制药株式会社 膜透过性高的环状肽化合物及包含其的文库
EP3699276A4 (en) * 2017-10-16 2021-07-28 The University Of Tokyo MODIFICATION OF ARM D AND T ARNT IMPROVING DAMINO ACID AND BETA AMINO ACID CAPTURE
JPWO2019139126A1 (ja) 2018-01-11 2021-04-08 国立大学法人 東京大学 Ntcp阻害剤
EP3904568A4 (en) * 2018-12-26 2024-03-20 Chugai Seiyaku Kabushiki Kaisha Mutated trna for codon expansion
WO2022104001A1 (en) * 2020-11-13 2022-05-19 Bristol-Myers Squibb Company Expanded protein libraries and uses thereof

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