JPWO2021132546A5 - - Google Patents

Download PDF

Info

Publication number
JPWO2021132546A5
JPWO2021132546A5 JP2021567657A JP2021567657A JPWO2021132546A5 JP WO2021132546 A5 JPWO2021132546 A5 JP WO2021132546A5 JP 2021567657 A JP2021567657 A JP 2021567657A JP 2021567657 A JP2021567657 A JP 2021567657A JP WO2021132546 A5 JPWO2021132546 A5 JP WO2021132546A5
Authority
JP
Japan
Prior art keywords
trna
character
composition according
codon
anticodon
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021567657A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO2021132546A1 (https=
JP7744244B2 (ja
Filing date
Publication date
Priority claimed from PCT/JP2019/051241 external-priority patent/WO2020138336A1/ja
Application filed filed Critical
Priority claimed from PCT/JP2020/048652 external-priority patent/WO2021132546A1/ja
Publication of JPWO2021132546A1 publication Critical patent/JPWO2021132546A1/ja
Publication of JPWO2021132546A5 publication Critical patent/JPWO2021132546A5/ja
Priority to JP2025151312A priority Critical patent/JP2025172162A/ja
Application granted granted Critical
Publication of JP7744244B2 publication Critical patent/JP7744244B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2021567657A 2019-12-26 2020-12-25 翻訳用組成物及びペプチドの製造方法 Active JP7744244B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025151312A JP2025172162A (ja) 2019-12-26 2025-09-11 翻訳用組成物及びペプチドの製造方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
PCT/JP2019/051241 WO2020138336A1 (ja) 2018-12-26 2019-12-26 コドン拡張のための変異tRNA
JPPCT/JP2019/051241 2019-12-26
JP2020109292 2020-06-25
JP2020109292 2020-06-25
PCT/JP2020/048652 WO2021132546A1 (ja) 2019-12-26 2020-12-25 翻訳用組成物及びペプチドの製造方法

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025151312A Division JP2025172162A (ja) 2019-12-26 2025-09-11 翻訳用組成物及びペプチドの製造方法

Publications (3)

Publication Number Publication Date
JPWO2021132546A1 JPWO2021132546A1 (https=) 2021-07-01
JPWO2021132546A5 true JPWO2021132546A5 (https=) 2023-12-08
JP7744244B2 JP7744244B2 (ja) 2025-09-25

Family

ID=76573318

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021567657A Active JP7744244B2 (ja) 2019-12-26 2020-12-25 翻訳用組成物及びペプチドの製造方法
JP2025151312A Pending JP2025172162A (ja) 2019-12-26 2025-09-11 翻訳用組成物及びペプチドの製造方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025151312A Pending JP2025172162A (ja) 2019-12-26 2025-09-11 翻訳用組成物及びペプチドの製造方法

Country Status (6)

Country Link
US (1) US20230108274A1 (https=)
EP (1) EP4026906A4 (https=)
JP (2) JP7744244B2 (https=)
KR (1) KR20220121831A (https=)
CN (1) CN114641569A (https=)
WO (1) WO2021132546A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI787670B (zh) 2011-12-28 2022-12-21 日商中外製藥股份有限公司 具有環狀部之胜肽化合物及其醫藥組成物
DK3269809T3 (da) 2015-03-13 2022-09-12 Chugai Pharmaceutical Co Ltd MODIFICERET AMINOACYL-tRNA-SYNTETASE OG ANVENDELSE DERAF
US12391971B2 (en) 2017-01-31 2025-08-19 Chugai Seiyaku Kabushiki Kaisha Method for synthesizing peptides in cell-free translation system
WO2018225851A1 (ja) 2017-06-09 2018-12-13 中外製薬株式会社 N-置換アミノ酸を含むペプチドの合成方法
EP3878836B1 (en) 2018-11-07 2025-07-23 Chugai Seiyaku Kabushiki Kaisha O-substituted serine derivative production method
KR20210139366A (ko) 2019-03-15 2021-11-22 추가이 세이야쿠 가부시키가이샤 방향족 아미노산 유도체의 제조 방법
PE20221323A1 (es) 2019-11-07 2022-09-09 Chugai Pharmaceutical Co Ltd Compuesto de peptidos ciclicos que tiene accion inhibidora de kras
CA3256645A1 (en) 2022-05-06 2025-04-23 Chugai Seiyaku Kabushiki Kaisha CYCLIC COMPOUND HAVING A SELECTIVE KRAS INHIBITORY EFFECT ON HRAS AND NRAS

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006500927A (ja) * 2002-09-13 2006-01-12 ザ・ユニバーシティ・オブ・クイーンズランド コドン翻訳効率に基づく遺伝子発現系
WO2006135096A1 (ja) 2005-06-14 2006-12-21 Gifu University 部位特異的にタンパク質にチロシンアナログを導入する方法
AU2006317944A1 (en) 2005-11-24 2007-05-31 Riken Method for producing proteins comprising non-natural amino acids incorporated therein
US8188260B2 (en) 2005-12-06 2012-05-29 The University Of Tokyo Versatile acylation catalytic RNAs and uses thereof
AU2007224019A1 (en) 2006-03-03 2007-09-13 California Institute Of Technology Site-specific incorporation of amino acids into molecules
WO2008001947A1 (en) 2006-06-28 2008-01-03 Riken MUTANT SepRS, AND METHOD FOR SITE-SPECIFIC INTRODUCTION OF PHOSPHOSERINE INTO PROTEIN BY USING THE SAME
WO2010141851A1 (en) 2009-06-05 2010-12-09 Salk Institute For Biological Studies Improving unnatural amino acid incorporation in eukaryotic cells
JP5725467B2 (ja) * 2010-08-27 2015-05-27 国立大学法人 東京大学 新規人工翻訳合成系
JP5818237B2 (ja) 2010-09-09 2015-11-18 国立大学法人 東京大学 N−メチルアミノ酸およびその他の特殊アミノ酸を含む特殊ペプチド化合物ライブラリーの翻訳構築と活性種探索法
US10195578B2 (en) 2010-12-03 2019-02-05 The University Of Tokyo Peptide library production method, peptide library, and screening method
TWI787670B (zh) * 2011-12-28 2022-12-21 日商中外製藥股份有限公司 具有環狀部之胜肽化合物及其醫藥組成物
JP6440055B2 (ja) * 2013-05-10 2018-12-19 国立大学法人 東京大学 ペプチドライブラリの製造方法、ペプチドライブラリ、及びスクリーニング方法
JP6754997B2 (ja) 2013-08-26 2020-09-16 国立大学法人 東京大学 大環状ペプチド、その製造方法、及び大環状ペプチドライブラリを用いるスクリーニング方法
WO2015120287A2 (en) 2014-02-06 2015-08-13 Yale University Compositions and methods of use thereof for making polypeptides with many instances of nonstandard amino acids
JP6814533B2 (ja) * 2015-09-29 2021-01-20 村上 裕 タンパク質を製造するための翻訳系、及びタンパク質の製造方法
TW201811817A (zh) 2016-09-13 2018-04-01 日商第一三共股份有限公司 血小板反應素1結合肽
US12391971B2 (en) 2017-01-31 2025-08-19 Chugai Seiyaku Kabushiki Kaisha Method for synthesizing peptides in cell-free translation system
JP7232758B2 (ja) 2017-06-09 2023-03-06 中外製薬株式会社 膜透過性の高い環状ペプチド化合物、及びこれを含むライブラリ
SG11202003483SA (en) * 2017-10-16 2020-07-29 Univ Tokyo MODIFICATION OF D AND T ARMS OF TRNA ENHANCING D-AMINO ACID AND ß-AMINO ACID UPTAKE
CN111867616A (zh) 2018-01-11 2020-10-30 国立大学法人东京大学 Ntcp抑制剂
WO2020138336A1 (ja) * 2018-12-26 2020-07-02 中外製薬株式会社 コドン拡張のための変異tRNA
WO2022104001A1 (en) * 2020-11-13 2022-05-19 Bristol-Myers Squibb Company Expanded protein libraries and uses thereof

Similar Documents

Publication Publication Date Title
JPWO2021132546A5 (https=)
Song et al. Requirement of a 3′-Terminal Stem-loop inin VitroTranscription by an RNA-dependent RNA Polymerase
Cantatore et al. The complete nucleotide sequence, gene organization, and genetic code of the mitochondrial genome of Paracentrotus lividus
Yokobori et al. Transfer RNA editing in land snail mitochondria.
Ahlquist et al. cDNA cloning and in vitro transcription of the complete brome mosaic virus genome
Staton et al. Mitochondrial gene arrangement of the horseshoe crab Limulus polyphemus L.: conservation of major features among arthropod classes.
Dreher Viral tRNAs and tRNA‐like structures
JP2019536425A5 (https=)
Vázquez et al. Mutation analysis of the GDD sequence motif of a calicivirus RNA-dependent RNA polymerase
Mitchell et al. Conservation of a potential metal binding motif despite extensive sequence diversity in the rotavirus nonstructural protein NS53
ES2982551T3 (es) Variantes de desoxinucleotidil transferasa terminal y usos de las mismas
NZ580378A (en) Recombinant expression vector elements (reves) for enhancing expression of recombinant proteins in host cells
Goodman et al. The nucleotide sequence at the 5′-terminus of the Qβ RNA minus strand
Osman et al. Identification of a region of the tobacco mosaic virus 126-and 183-kilodalton replication proteins which binds specifically to the viral 3′-terminal tRNA-like structure
Sivakumaran et al. Initiation of genomic plus-strand RNA synthesis from DNA and RNA templates by a viral RNA-dependent RNA polymerase
JP2021522825A5 (https=)
CN107460177A (zh) 可利用化学修饰核苷酸的rna聚合酶突变体
Palmer et al. Sequence of the genome of lactate dehydrogenase-elevating virus: heterogenicity between strains P and C
WO2000066722B1 (en) Collection of prokaryotic dna for two hybrid systems helicobacter pylori protein-protein interactions and application thereof
Panavas et al. Mechanism of stimulation of plus-strand synthesis by an RNA replication enhancer in a tombusvirus
CN120366260A (zh) Rna聚合酶变体及其应用
Song et al. Synthesis of novel products in vitro by an RNA-dependent RNA polymerase
WO2026011785A1 (zh) 一种Nedosiran的制备方法
WO2026011784A1 (zh) 一种Lumasiran的制备方法
US8003348B2 (en) Method for the mass expression of an antimicrobial peptide by co-expression of a basic antimicrobial peptide and an acidic peptide using a translational coupling system