JPWO2020223536A5 - - Google Patents

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Publication number
JPWO2020223536A5
JPWO2020223536A5 JP2021564465A JP2021564465A JPWO2020223536A5 JP WO2020223536 A5 JPWO2020223536 A5 JP WO2020223536A5 JP 2021564465 A JP2021564465 A JP 2021564465A JP 2021564465 A JP2021564465 A JP 2021564465A JP WO2020223536 A5 JPWO2020223536 A5 JP WO2020223536A5
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JP
Japan
Prior art keywords
alkyl
disease
syndrome
halo
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021564465A
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English (en)
Japanese (ja)
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JP2022530647A (ja
JP2022530647A5 (https=
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/030817 external-priority patent/WO2020223536A1/en
Publication of JP2022530647A publication Critical patent/JP2022530647A/ja
Publication of JP2022530647A5 publication Critical patent/JP2022530647A5/ja
Publication of JPWO2020223536A5 publication Critical patent/JPWO2020223536A5/ja
Pending legal-status Critical Current

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JP2021564465A 2019-04-30 2020-04-30 統合的ストレス経路の置換シクロアルキルモジュレーター Pending JP2022530647A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962840945P 2019-04-30 2019-04-30
US62/840,945 2019-04-30
PCT/US2020/030817 WO2020223536A1 (en) 2019-04-30 2020-04-30 Substituted cyclolakyls as modulators of the integrated stress pathway

Publications (3)

Publication Number Publication Date
JP2022530647A JP2022530647A (ja) 2022-06-30
JP2022530647A5 JP2022530647A5 (https=) 2023-05-12
JPWO2020223536A5 true JPWO2020223536A5 (https=) 2023-05-12

Family

ID=71465400

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021564465A Pending JP2022530647A (ja) 2019-04-30 2020-04-30 統合的ストレス経路の置換シクロアルキルモジュレーター

Country Status (15)

Country Link
US (2) US20210363136A1 (https=)
EP (1) EP3962899A1 (https=)
JP (1) JP2022530647A (https=)
KR (1) KR20220016467A (https=)
CN (1) CN114401952A (https=)
AR (1) AR118836A1 (https=)
AU (2) AU2020266592B2 (https=)
BR (1) BR112021021754A2 (https=)
CA (1) CA3138144A1 (https=)
IL (1) IL287660A (https=)
MX (1) MX2021013193A (https=)
SG (1) SG11202111970WA (https=)
TW (1) TW202106671A (https=)
UY (1) UY38685A (https=)
WO (1) WO2020223536A1 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3071024A1 (en) 2017-08-09 2019-02-14 Denali Therapeutics Inc. Compounds, compositions and methods
CN111201245B (zh) 2017-09-01 2024-04-05 戴纳立制药公司 化合物、组合物和方法
WO2019090088A1 (en) 2017-11-02 2019-05-09 Calico Life Sciences Llc Modulators of the integrated stress pathway
CN111757739A (zh) 2017-12-13 2020-10-09 普拉西斯生物技术有限责任公司 整合应激反应路径抑制剂
AU2019282253A1 (en) 2018-06-05 2020-11-26 Altos Labs, Inc. Inhibitors of integrated stress response pathway
TW202545902A (zh) 2018-10-11 2025-12-01 美商嘉來克生命科學有限責任公司 整合應激路徑之前藥調節劑
EP3924341A4 (en) 2019-02-13 2022-11-02 Denali Therapeutics Inc. Compounds, compositions and methods
SG11202108552QA (en) 2019-02-13 2021-09-29 Denali Therapeutics Inc Compounds, compositions and methods
WO2020252207A1 (en) 2019-06-12 2020-12-17 Praxis Biotech LLC Modulators of integrated stress response pathway
CN115190813B (zh) 2020-03-11 2024-10-15 埃沃特克国际有限责任公司 整合应激反应途径的调节剂
EP4232153A1 (en) 2020-10-22 2023-08-30 Evotec International GmbH Modulators of the integrated stress response pathway
RS66455B1 (sr) 2020-10-22 2025-02-28 Evotec Int Gmbh Modulatori puta integrisanog odgovora na stres
EP4232447A1 (en) 2020-10-22 2023-08-30 Evotec International GmbH Modulators of the integrated stress response pathway
IL302440A (en) * 2020-10-30 2023-06-01 Calico Life Sciences Llc Combined pressure pathway modulators
TWI863059B (zh) * 2021-12-23 2024-11-21 李長榮化學工業股份有限公司 二胺化合物及其製備方法、二胺化合物形成的高分子及其用途
EP4452952A4 (en) * 2021-12-25 2025-12-03 Council Of Scient And Industrial Research An Indian Registered Body Incorporated Under Regn Of Soc A PREPARATION OF QUINAZOLINEDIONES AND THEIR USE
CN114839296B (zh) * 2022-05-13 2023-12-22 普研(上海)标准技术服务有限公司 食品中牛肉酮的检测方法
CN116768877B (zh) * 2022-05-30 2026-03-31 中国药科大学 Isr抑制剂及其制备方法和应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI763668B (zh) * 2016-05-05 2022-05-11 美商嘉來克生命科學有限責任公司 整合應激途徑之調節劑
TW201808888A (zh) * 2016-05-05 2018-03-16 嘉來克生命科學有限責任公司 整合應激途徑之調節劑
WO2018225093A1 (en) * 2017-06-07 2018-12-13 Glaxosmithkline Intellectual Property Development Limited Chemical compounds as atf4 pathway inhibitors
UY37956A (es) * 2017-11-02 2019-05-31 Abbvie Inc Moduladores de la vía de estrés integrada
UY37958A (es) * 2017-11-02 2019-05-31 Abbvie Inc Moduladores de la vía de estrés integrada
UY37957A (es) * 2017-11-02 2019-05-31 Abbvie Inc Moduladores de la vía de estrés integrada
WO2019183589A1 (en) * 2018-03-23 2019-09-26 Denali Therapeutics Inc. Modulators of eukaryotic initiation factor 2
PE20220572A1 (es) * 2019-04-30 2022-04-20 Calico Life Sciences Llc Moduladores de la via integrada del estres

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