JPWO2020204055A5 - - Google Patents

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Publication number
JPWO2020204055A5
JPWO2020204055A5 JP2021512163A JP2021512163A JPWO2020204055A5 JP WO2020204055 A5 JPWO2020204055 A5 JP WO2020204055A5 JP 2021512163 A JP2021512163 A JP 2021512163A JP 2021512163 A JP2021512163 A JP 2021512163A JP WO2020204055 A5 JPWO2020204055 A5 JP WO2020204055A5
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JP
Japan
Prior art keywords
dna
nucleic acid
polynucleotide
cassette
genome
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JP2021512163A
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English (en)
Japanese (ja)
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JPWO2020204055A1 (https=
JP7522100B2 (ja
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Priority claimed from PCT/JP2020/014980 external-priority patent/WO2020204055A1/ja
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Publication of JPWO2020204055A5 publication Critical patent/JPWO2020204055A5/ja
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JP2021512163A 2019-04-02 2020-04-01 標的特異的な外来遺伝子の導入方法 Active JP7522100B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2019070329 2019-04-02
JP2019070329 2019-04-02
PCT/JP2020/014980 WO2020204055A1 (ja) 2019-04-02 2020-04-01 標的特異的な外来遺伝子の導入方法

Publications (3)

Publication Number Publication Date
JPWO2020204055A1 JPWO2020204055A1 (https=) 2020-10-08
JPWO2020204055A5 true JPWO2020204055A5 (https=) 2024-01-23
JP7522100B2 JP7522100B2 (ja) 2024-07-24

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JP2021512163A Active JP7522100B2 (ja) 2019-04-02 2020-04-01 標的特異的な外来遺伝子の導入方法

Country Status (12)

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US (1) US12344859B2 (https=)
EP (1) EP3950938A4 (https=)
JP (1) JP7522100B2 (https=)
KR (1) KR102655024B1 (https=)
CN (1) CN113661238B (https=)
AU (1) AU2020252840B2 (https=)
CA (1) CA3134705A1 (https=)
IL (1) IL286630B2 (https=)
MX (1) MX2021011903A (https=)
SG (1) SG11202110076PA (https=)
TW (1) TWI851703B (https=)
WO (1) WO2020204055A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025216715A1 (en) * 2024-04-12 2025-10-16 Agency For Science, Technology And Research Identification of transcriptional hotspots in cho cells

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FR2707189B1 (fr) 1993-07-09 1995-10-13 Gradient Ass Procédé de traitement de résidus de combustion et installation de mise en Óoeuvre dudit procédé.
US6800457B2 (en) 1998-09-22 2004-10-05 Bristol-Myers Squibb Company Expression vectors containing hot spot for increased recombinant protein expression in transfected cells
US6521419B1 (en) 1998-09-22 2003-02-18 Kanakaraju Koduri Expression vectors containing hot spot for increased recombinant protein expression in transfected cells
DE60021373T2 (de) * 1999-05-10 2006-04-27 Chugai Seiyaku K.K. Verfahren der zellkultivierung
EP1332209B1 (en) 2000-09-08 2009-11-11 Universität Zürich Collections of repeat proteins comprising repeat modules
EP2141243A3 (en) 2000-10-16 2010-01-27 Brystol-Myers Squibb Company Protein scaffolds for antibody mimics and other binding proteins
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CN1618955A (zh) 2003-11-20 2005-05-25 中国人民解放军军事医学科学院生物工程研究所 一种CHO/dhfr-细胞定点整合表达系统
EP1835022B1 (en) * 2005-01-05 2015-02-11 Chugai Seiyaku Kabushiki Kaisha Cell culture method and utilization of the same
JP2007325571A (ja) 2006-06-09 2007-12-20 Toto Ltd 組換え哺乳類動物細胞を用いたタンパク質生産方法
CA2659574C (en) 2006-08-02 2017-04-25 The Uab Research Foundation Methods and compositions related to soluble monoclonal variable lymphocyte receptors of defined antigen specificity
EP2150617B1 (en) * 2007-06-04 2014-10-22 Regeneron Pharmaceuticals, Inc. Enhanced expression and stability regions
US8071332B2 (en) 2007-08-10 2011-12-06 Toto Ltd. Recombinant mammal cells, method of producing thereof, and method of producing proteins of interest
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JP2010210772A (ja) 2009-03-13 2010-09-24 Dainippon Screen Mfg Co Ltd 液晶表示装置の製造方法
US20130034875A1 (en) 2009-10-01 2013-02-07 Toto Ltd. Dna construct, and process for production of recombinant cho cell using same
CN105969807A (zh) 2011-04-05 2016-09-28 斯克利普斯研究所 染色体着陆垫及相关用途
EP2711428A1 (en) 2012-09-21 2014-03-26 Lonza Biologics plc. Site-specific integration
BR112015031639A2 (pt) 2013-06-19 2019-09-03 Sigma Aldrich Co Llc integração alvo
JP6708548B2 (ja) 2013-12-20 2020-06-10 ノバルティス アーゲー 新規真核細胞および目的の生成物を組換え発現させるための方法
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BR112017008022A2 (pt) * 2014-10-23 2018-02-20 Regeneron Pharmaceuticals, Inc. célula, polinucleotídeo, veículo, e, métodos para modificação de um genoma de células cho e para preparação de uma proteína de interesse.
CN104818253B (zh) 2015-03-24 2018-03-09 成都贝爱特生物科技有限公司 靶向定点整合cho细胞系的改造及其用途
DE102015222931A1 (de) * 2015-11-20 2017-05-24 Continental Teves Ag & Co. Ohg Anordnung zur Messung eines durch Bremskraft erzeugten Verschiebeweges
BR112018071285A2 (pt) 2016-04-20 2019-02-12 Regeneron Pharma célula, conjunto de vetores, vetor, sistema, e, método
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CA3068779A1 (en) 2017-08-11 2019-02-14 Boehringer Ingelheim International Gmbh Integration sites in cho cells

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