|
PT765313E
(pt)
|
1994-06-17 |
2003-11-28 |
Hoffmann La Roche |
Derivados de n,n'-bis(quinolin-4-il)-diamina a sua preparacao e a sua utilizacao como agentes anti-malaria
|
|
AU4515696A
(en)
|
1994-12-12 |
1996-07-03 |
Merck & Co., Inc. |
Substituted 2-aminopyridines as inhibitors of nitric oxide synthase
|
|
SE9603285D0
(sv)
|
1996-09-10 |
1996-09-10 |
Astra Ab |
New compounds
|
|
US5874438A
(en)
|
1996-10-11 |
1999-02-23 |
Bayer Aktiengesellschaft |
2,2'-bridged bis-2,4-diaminoquinazolines
|
|
US20040138284A1
(en)
|
2000-02-11 |
2004-07-15 |
Matthias Wiesner |
Indol-3-yl derivatives
|
|
GB0014022D0
(en)
|
2000-06-08 |
2000-08-02 |
Novartis Ag |
Organic compounds
|
|
AU2001288432A1
(en)
|
2000-09-01 |
2002-03-22 |
Icos Corporation |
Materials and methods to potentiate cancer treatment
|
|
EP1217000A1
(en)
|
2000-12-23 |
2002-06-26 |
Aventis Pharma Deutschland GmbH |
Inhibitors of factor Xa and factor VIIa
|
|
CH1427415H1
(de)
|
2001-09-21 |
2023-12-21 |
Bristol Myers Squibb Holdings Ireland |
Lactamhaltige verbindungen und ihre derivate als faktor-xa-hemmer
|
|
WO2003059891A1
(en)
|
2002-01-18 |
2003-07-24 |
Pharmacia Corporation |
Substituted pyridazinones as inhibitors of p38
|
|
AU2003273179A1
(en)
|
2002-05-10 |
2003-12-12 |
Bristol-Myers Squibb Company |
1,1-disubstituted cycloalkyl derivatives as factor xa inhibitors
|
|
CN1671639A
(zh)
|
2002-08-23 |
2005-09-21 |
康涅狄格大学 |
新型联苯大麻素和类似联苯的大麻素
|
|
EP1464335A3
(en)
|
2003-03-31 |
2007-05-09 |
Taisho Pharmaceutical Co. Ltd. |
Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist
|
|
MXJL05000046A
(es)
|
2003-04-22 |
2005-12-22 |
Avanir Pharmaceuticals |
Mediadores de transporte reverso de colesterol para el tratamiento de hipercolesterolemia.
|
|
PE20050986A1
(es)
*
|
2004-06-09 |
2006-02-03 |
Avanir Pharmaceuticals |
Derivados heterociclicos mediadores del transporte inverso de colesterol
|
|
AU2005286731A1
(en)
|
2004-09-20 |
2006-03-30 |
Xenon Pharmaceuticals Inc. |
Pyridazine derivatives for inhibiting human stearoyl-CoA-desaturase
|
|
US20080090863A1
(en)
|
2004-09-30 |
2008-04-17 |
Taisho Pharmaceutical Co., Ltd. |
Pyridine Derivatives and Their Use as Medicaments for Treating Diseases Related to Mch Receptor
|
|
US7381732B2
(en)
|
2004-10-26 |
2008-06-03 |
Bristol-Myers Squibb Company |
Pyrazolobenzamides and derivatives as factor Xa inhibitors
|
|
CA2585490A1
(en)
|
2004-11-12 |
2006-05-18 |
Galapagos Nv |
Nitrogen heteroaromatic compounds which bind to the active site of protein kinase enzymes
|
|
GB0428082D0
(en)
|
2004-12-22 |
2005-01-26 |
Welcome Trust The Ltd |
Therapeutic compounds
|
|
WO2006126081A2
(en)
|
2005-05-24 |
2006-11-30 |
Pharmacia & Upjohn Company Llc |
Pyridino [2 , 3-b] pyrazinones as pde-5 inhibitors
|
|
CA2612227C
(en)
|
2005-06-14 |
2014-04-22 |
Taigen Biotechnology Co., Ltd. |
Pyrimidine compounds
|
|
US20070203236A1
(en)
|
2006-01-11 |
2007-08-30 |
Smith Jeffrey W |
Novel antagonists of the human fatty acid synthase thioesterase
|
|
JP2007291087A
(ja)
|
2006-03-29 |
2007-11-08 |
Taisho Pharmaceut Co Ltd |
ピリジン誘導体及びその使用に関連する治療法
|
|
ES2397283T3
(es)
|
2006-07-25 |
2013-03-06 |
Cephalon, Inc. |
Derivados de piridizinona
|
|
US20080255155A1
(en)
|
2006-10-18 |
2008-10-16 |
Stephane Raeppel |
Kinase inhibitors and uses thereof
|
|
US20100144793A1
(en)
|
2006-11-24 |
2010-06-10 |
Ac Immune Sa |
Novel compounds for the treatment of diseases associated with amyloid or amyloid-like proteins
|
|
MX2009005879A
(es)
|
2006-12-13 |
2009-09-09 |
Givaudan Nederland Services B |
Derivado modulador del sabor de un acido carboxilico y una purina, pirimidina, nucleosido o nucleotido.
|
|
CA2703712A1
(en)
*
|
2007-10-26 |
2009-04-30 |
Joseph A. Hedrick |
Anti-pcsk9 and methods for treating lipid and cholesterol disorders
|
|
US8304413B2
(en)
|
2008-06-03 |
2012-11-06 |
Intermune, Inc. |
Compounds and methods for treating inflammatory and fibrotic disorders
|
|
WO2010048149A2
(en)
|
2008-10-20 |
2010-04-29 |
Kalypsys, Inc. |
Heterocyclic modulators of gpr119 for treatment of disease
|
|
CN102596946B
(zh)
|
2009-08-05 |
2015-06-17 |
港大科桥有限公司 |
抗病毒化合物及其制备和使用方法
|
|
WO2011147199A1
(en)
|
2010-05-28 |
2011-12-01 |
Versitech Limited |
Compounds and methods for treating viral infections
|
|
KR20130111512A
(ko)
|
2010-06-04 |
2013-10-10 |
코와 가부시키가이샤 |
광학 활성 디벤질아민 유도체 및 그의 제조 방법
|
|
WO2012009649A1
(en)
|
2010-07-16 |
2012-01-19 |
Anderson Gaweco |
Mif inhibitors and their uses
|
|
WO2012016133A2
(en)
|
2010-07-29 |
2012-02-02 |
President And Fellows Of Harvard College |
Ros1 kinase inhibitors for the treatment of glioblastoma and other p53-deficient cancers
|
|
WO2012088438A1
(en)
|
2010-12-22 |
2012-06-28 |
Eutropics Pharmaceuticals, Inc. |
Compositions and methods useful for treating diseases
|
|
CN103339110A
(zh)
|
2011-01-28 |
2013-10-02 |
诺瓦提斯公司 |
作为cdk9抑制剂的取代的杂-联芳基化合物及其用途
|
|
EP3354640A3
(en)
|
2011-04-13 |
2018-10-31 |
Innovimmune Biotherapeutics, Inc. |
Mif inhibitors and their uses
|
|
US10533000B2
(en)
|
2011-05-26 |
2020-01-14 |
Sunovion Pharmaceuticals, Inc. |
Metabotrophic glutamate receptor 5 modulators and methods of use thereof
|
|
JP5741850B2
(ja)
|
2011-09-13 |
2015-07-01 |
コニカミノルタ株式会社 |
光学フィルム、それを含む偏光板および液晶表示装置
|
|
JPWO2013137371A1
(ja)
|
2012-03-15 |
2015-08-03 |
興和株式会社 |
新規ピリミジン化合物及びそれらを含有する医薬
|
|
KR20150059638A
(ko)
|
2012-05-25 |
2015-06-01 |
카타베이시스 파마슈티칼즈, 인코포레이티드 |
전구단백질 전환효소 섭틸리신/켁신 9형 저하 방법
|
|
CA2872110C
(en)
|
2012-07-18 |
2019-08-06 |
Sunshine Lake Pharma Co., Ltd. |
Nitrogenous heterocyclic derivatives and their application in drugs
|
|
TWI644899B
(zh)
|
2013-02-04 |
2018-12-21 |
健生藥品公司 |
Ｆｌａｐ調節劑
|
|
US10059671B2
(en)
|
2013-02-04 |
2018-08-28 |
Prexton Therapeutics Sa |
Positive allosteric modulators of mGluR3
|
|
EP3985003B1
(en)
|
2013-03-12 |
2023-08-09 |
Vertex Pharmaceuticals Incorporated |
Dna-pk inhibitors
|
|
WO2014170786A1
(en)
*
|
2013-04-17 |
2014-10-23 |
Pfizer Inc. |
N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
|
|
US9212182B2
(en)
|
2013-06-12 |
2015-12-15 |
Amgen Inc. |
Bicyclic sulfonamide compounds as sodium channel inhibitors
|
|
AR092240A1
(es)
|
2013-08-26 |
2015-04-08 |
Sunshine Lake Pharma Co Ltd |
Derivados heterociclicos nitrogenados y su aplicacion en farmacos
|
|
CN104558685B
(zh)
|
2013-10-24 |
2017-09-29 |
中国石油化工股份有限公司 |
一种磷氮膨胀型阻燃剂及其合成方法
|
|
JP2017516858A
(ja)
|
2014-05-30 |
2017-06-22 |
ユニヴェルシテ・パリ・デカルト |
Ｈｉｖ感染症の治療に使用するための１，３ジアミノ官能性を有する環式化合物
|
|
TWI744723B
(zh)
|
2014-06-20 |
2021-11-01 |
美商基利科學股份有限公司 |
多環型胺甲醯基吡啶酮化合物之合成
|
|
US9862701B2
(en)
|
2014-09-25 |
2018-01-09 |
Araxes Pharma Llc |
Inhibitors of KRAS G12C mutant proteins
|
|
WO2016054388A1
(en)
|
2014-10-03 |
2016-04-07 |
University Of Pittsburgh - Of The Commonwealth System Of Higher Education |
Glutaminase inhibitors
|
|
AU2016209321B2
(en)
|
2015-01-20 |
2019-05-09 |
Boehringer Ingelheim Animal Health USA Inc. |
Anthelmintic compounds, compositions and method of using thereof
|
|
MX2018008803A
(es)
|
2016-01-20 |
2018-11-09 |
Janssen Sciences Ireland Uc |
Pirimidinas sustituidas con arilo para su uso en la infeccion por virus influenza.
|
|
CN114539284A
(zh)
|
2016-03-16 |
2022-05-27 |
库拉肿瘤学公司 |
经取代的menin-mll抑制剂及使用方法
|
|
TW201808888A
(zh)
|
2016-05-05 |
2018-03-16 |
嘉來克生命科學有限責任公司 |
整合應激途徑之調節劑
|
|
WO2018106818A1
(en)
|
2016-12-07 |
2018-06-14 |
Kura Oncology, Inc. |
Methods of promoting beta cell proliferation
|
|
WO2018106820A1
(en)
|
2016-12-07 |
2018-06-14 |
Kura Oncology, Inc. |
Methods of promoting beta cell proliferation
|
|
EP3609882B1
(en)
|
2017-03-17 |
2022-07-13 |
Cardio Therapeutics Pty Ltd |
Heterocyclic inhibitors of pcsk9
|
|
EP3601249A4
(en)
|
2017-03-24 |
2020-12-16 |
Kura Oncology, Inc. |
METHODS OF TREATMENT OF MALIGNANT HEMOPATHIES AND EWING'S SARCOMA
|
|
JP7252908B2
(ja)
|
2017-06-14 |
2023-04-05 |
トレベナ・インコーポレイテッド |
Ｓ１ｐ１活性を調節するための化合物およびその使用法
|
|
CN109384712B
(zh)
|
2017-08-14 |
2021-05-07 |
北京宽厚医药科技有限公司 |
靶向nk1受体拮抗剂及其在化疗所致恶心、呕吐治疗中的应用
|
|
US11505560B2
(en)
|
2017-10-20 |
2022-11-22 |
Dana-Farber Cancer Institute, Inc. |
Heterobifunctional compounds with improved specificity
|
|
UY37957A
(es)
|
2017-11-02 |
2019-05-31 |
Abbvie Inc |
Moduladores de la vía de estrés integrada
|
|
WO2019111225A1
(en)
|
2017-12-08 |
2019-06-13 |
Avaliv Therapeutics |
Compounds and methods for the treatment of non‑alcoholic steatohepatitis
|
|
WO2019143675A1
(en)
|
2018-01-17 |
2019-07-25 |
Vertex Pharmaceuticals Incorporated |
Dna-pk inhibitors
|
|
AU2019257651B2
(en)
|
2018-04-24 |
2023-05-25 |
Vertex Pharmaceuticals Incorporated |
Pteridinone compounds and uses thereof
|
|
US20190374526A1
(en)
|
2018-06-06 |
2019-12-12 |
Merck Sharp & Dohme Corp. |
Substituted Heterocyclic Compounds as Inhibitors of PRDM9
|
|
CN113574055A
(zh)
*
|
2019-01-18 |
2021-10-29 |
阿斯利康(瑞典)有限公司 |
Pcsk9抑制剂及其使用方法
|