JPWO2020060010A5 - - Google Patents

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Publication number
JPWO2020060010A5
JPWO2020060010A5 JP2021539320A JP2021539320A JPWO2020060010A5 JP WO2020060010 A5 JPWO2020060010 A5 JP WO2020060010A5 JP 2021539320 A JP2021539320 A JP 2021539320A JP 2021539320 A JP2021539320 A JP 2021539320A JP WO2020060010 A5 JPWO2020060010 A5 JP WO2020060010A5
Authority
JP
Japan
Prior art keywords
iomeprol
producing
chloride
triiodoisophthalamide
hydroxyacetamide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021539320A
Other languages
English (en)
Japanese (ja)
Other versions
JP7357388B2 (ja
JP2021535933A (ja
Publication date
Priority claimed from KR1020180110628A external-priority patent/KR102128423B1/ko
Application filed filed Critical
Publication of JP2021535933A publication Critical patent/JP2021535933A/ja
Publication of JPWO2020060010A5 publication Critical patent/JPWO2020060010A5/ja
Application granted granted Critical
Publication of JP7357388B2 publication Critical patent/JP7357388B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2021539320A 2018-09-17 2019-07-02 造影剤イオメプロールの製造方法 Active JP7357388B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR10-2018-0110628 2018-09-17
KR1020180110628A KR102128423B1 (ko) 2018-09-17 2018-09-17 조영제 이오메프롤의 제조방법
PCT/KR2019/008008 WO2020060010A1 (ko) 2018-09-17 2019-07-02 조영제 이오메프롤의 제조방법

Publications (3)

Publication Number Publication Date
JP2021535933A JP2021535933A (ja) 2021-12-23
JPWO2020060010A5 true JPWO2020060010A5 (zh) 2022-07-05
JP7357388B2 JP7357388B2 (ja) 2023-10-06

Family

ID=69887351

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021539320A Active JP7357388B2 (ja) 2018-09-17 2019-07-02 造影剤イオメプロールの製造方法

Country Status (7)

Country Link
US (1) US11396490B2 (zh)
EP (1) EP3854780B1 (zh)
JP (1) JP7357388B2 (zh)
KR (1) KR102128423B1 (zh)
CN (1) CN113166040B (zh)
ES (1) ES2966931T3 (zh)
WO (1) WO2020060010A1 (zh)

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1193211B (it) 1979-08-09 1988-06-15 Bracco Ind Chimica Spa Derivati dell'acido 2,4,6-triiodo-isoftalico,metodo per la loro preparazione e mezzi di contrasto che li contengono
CA1327600C (en) * 1987-05-22 1994-03-08 Ernest Felder Process for the preparation of 5-acylamino-2,4,6- triiodo-or tribromo-benzoic acid derivatives and corresponding novel 5-acylamino-2,4,6-triiodo or tribromo-benzoic acid derivatives obtained by said process
IT1248741B (it) * 1991-02-26 1995-01-26 Bracco Spa Processo di concentrazione e di purificazione di composti organici
IL110391A (en) * 1993-07-30 1998-12-06 Zambon Spa Process for the formation of infamidol
IT1292037B1 (it) * 1997-05-30 1999-01-25 Bracco Spa Processo per la preparazione di 5-(acetil 62,3-diidrossipropil)- ammino)-n,n'-bis(2,3-diidrossipropil)-2,4,6-triiodo-1,3-benzen-
US6560229B1 (en) 1998-07-08 2003-05-06 Broadcom Corporation Network switching architecture with multiple table synchronization, and forwarding of both IP and IPX packets
IT1303797B1 (it) 1998-11-27 2001-02-23 Bracco Spa Processo per la preparazione di n,n'-bis(2,3-diidrossipropil)-5-((idrossiacetil)metilammino)-2,4,6-triiodo-1,3-benzendicarbossammide.
EP2240432B1 (en) * 2008-01-14 2012-07-04 Mallinckrodt LLC Process for the preparation of iosimenol
IT1403988B1 (it) 2010-07-15 2013-11-08 Bracco Imaging Spa Processo per la preparazione di agenti di contrasto.
CN102276498B (zh) * 2011-06-08 2013-10-30 浙江司太立制药股份有限公司 一种新的三碘苯类化合物造影剂
CN102363600B (zh) * 2011-10-24 2013-07-17 江苏省原子医学研究所 一种碘美普尔的制备方法
EP2917174B1 (en) 2012-11-12 2018-09-12 Ge Healthcare As Preparation of intermediates of x-ray contrast agents
DK3371147T3 (da) * 2015-11-04 2021-05-25 Otsuka Pharma Co Ltd Innovativ fremstilling og krystallisering af iosimenol
KR101833334B1 (ko) * 2016-04-29 2018-02-28 (주)유케이케미팜 신규 중간체 화합물 및 이를 이용한 이오메프롤의 제조방법
CN107253918A (zh) 2017-07-27 2017-10-17 成都丽璟科技有限公司 一种制备碘美普尔的新方法

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