JPWO2019165197A5 - - Google Patents
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- Publication number
- JPWO2019165197A5 JPWO2019165197A5 JP2020543913A JP2020543913A JPWO2019165197A5 JP WO2019165197 A5 JPWO2019165197 A5 JP WO2019165197A5 JP 2020543913 A JP2020543913 A JP 2020543913A JP 2020543913 A JP2020543913 A JP 2020543913A JP WO2019165197 A5 JPWO2019165197 A5 JP WO2019165197A5
- Authority
- JP
- Japan
- Prior art keywords
- tissue
- donor
- thymic
- recipient
- thymus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024005418A JP2024041955A (ja) | 2018-02-23 | 2024-01-17 | 同種固形臓器移植に対するドナー特異的寛容を促進する培養胸腺組織移植 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862634377P | 2018-02-23 | 2018-02-23 | |
| US62/634,377 | 2018-02-23 | ||
| PCT/US2019/019137 WO2019165197A1 (en) | 2018-02-23 | 2019-02-22 | Cultured thymus tissue transplantation promotes donor-specific tolerance to allogeneic solid organ transplants |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024005418A Division JP2024041955A (ja) | 2018-02-23 | 2024-01-17 | 同種固形臓器移植に対するドナー特異的寛容を促進する培養胸腺組織移植 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021516224A JP2021516224A (ja) | 2021-07-01 |
| JP2021516224A5 JP2021516224A5 (https=) | 2022-01-31 |
| JPWO2019165197A5 true JPWO2019165197A5 (https=) | 2022-01-31 |
| JP7499178B2 JP7499178B2 (ja) | 2024-06-13 |
Family
ID=67687403
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020543913A Active JP7499178B2 (ja) | 2018-02-23 | 2019-02-22 | 同種固形臓器移植に対するドナー特異的寛容を促進する培養胸腺組織移植 |
| JP2024005418A Pending JP2024041955A (ja) | 2018-02-23 | 2024-01-17 | 同種固形臓器移植に対するドナー特異的寛容を促進する培養胸腺組織移植 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024005418A Pending JP2024041955A (ja) | 2018-02-23 | 2024-01-17 | 同種固形臓器移植に対するドナー特異的寛容を促進する培養胸腺組織移植 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US12064452B2 (https=) |
| EP (2) | EP3755346B1 (https=) |
| JP (2) | JP7499178B2 (https=) |
| KR (2) | KR102805282B1 (https=) |
| CN (1) | CN112074277A (https=) |
| AU (1) | AU2019225151B2 (https=) |
| BR (1) | BR112020016614A2 (https=) |
| CA (1) | CA3089593A1 (https=) |
| IL (1) | IL276706A (https=) |
| MX (1) | MX2020008590A (https=) |
| SG (1) | SG11202007498YA (https=) |
| WO (1) | WO2019165197A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021034650A1 (en) | 2019-08-19 | 2021-02-25 | Duke University & Medical Center | Methods of determining the suitability of cultured thymus tissue for implantation into humans and associated methods of use |
| CN115287262B (zh) * | 2022-01-28 | 2024-04-02 | 浙江中医药大学 | 一种胸腺类器官微球及其制备方法与应用 |
| WO2024042488A1 (en) | 2022-08-24 | 2024-02-29 | Enzyvant Therapeutics Gmbh | Thymic exosome assays, and methods of producing t cell depleted thymus tissue and uses thereof |
| WO2025068989A1 (en) | 2023-09-29 | 2025-04-03 | Enzyvant Therapeutics Gmbh | Device for cultivating and transporting biological tissue |
| JP7627920B1 (ja) | 2023-12-11 | 2025-02-07 | 浩 宮内 | 移植材料の評価方法 |
| CN118203653A (zh) * | 2024-02-06 | 2024-06-18 | 同济大学 | 一种利用胸腺疫苗降低或消除同种异体移植排斥的方法 |
| WO2025226936A1 (en) * | 2024-04-24 | 2025-10-30 | Revivicor, Inc. | Donor-specific tolerance-inducing regimens for xenotransplantation |
| WO2025240817A1 (en) * | 2024-05-17 | 2025-11-20 | The Trustees Of Columbia University In The City Of New York | Thymoliver and methods of constructing thereof |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5624823A (en) | 1991-11-22 | 1997-04-29 | The General Hospital Corporation | DNA encoding procine interleukin-10 |
| EP0667792A1 (en) | 1991-11-22 | 1995-08-23 | The General Hospital Corporation | Specific tolerance in transplantation |
| ATE215375T1 (de) | 1992-01-08 | 2002-04-15 | Gen Hospital Corp | Induzierte toleranz gegen transplantate |
| US5658564A (en) | 1992-02-19 | 1997-08-19 | The General Hospital Corporation | Xenograft thymus |
| US6911220B1 (en) * | 1992-02-19 | 2005-06-28 | The General Hospital Corporation | Allogeneic and xenogeneic transplantation |
| US5876708A (en) | 1992-02-19 | 1999-03-02 | The General Hospital Corporation | Allogeneic and xenogeneic transplantation |
| US5766944A (en) * | 1996-12-31 | 1998-06-16 | Ruiz; Margaret Eileen | T cell differentiation of CD34+ stem cells in cultured thymic epithelial fragments |
| AUPP977899A0 (en) | 1999-04-15 | 1999-05-13 | Monash University | Improvement of t cell mediated immunity |
| US20040096971A1 (en) * | 2000-12-22 | 2004-05-20 | Blackburn Catherine Clare | Thymic epithelial progenitor cells and uses thereof |
| US20040086508A1 (en) * | 2001-06-05 | 2004-05-06 | Advanced Biotherapy, Inc. | Treatment of organ transplant rejection |
| US7037900B2 (en) | 2001-10-12 | 2006-05-02 | Supergen, Inc. | Composition and method for treating graft-versus-host disease |
| US7402432B2 (en) * | 2003-12-12 | 2008-07-22 | The Brigham And Women's Hospital, Inc. | Process for producing T lymphocytes |
| CA2580271A1 (en) * | 2004-10-05 | 2006-04-20 | Genentech, Inc. | Method for treating vasculitis |
| WO2006107601A2 (en) * | 2005-04-06 | 2006-10-12 | Duke University | Parathyroid and thymus transplantation in digeorge syndrome subjects |
| EP1993573A2 (en) * | 2006-01-13 | 2008-11-26 | Renovar, Inc. | Systems and methods for monitoring immune responses and predicting outcomes in transplant recipients |
| US20080131441A1 (en) | 2006-09-26 | 2008-06-05 | Manikkam Suthanthiran | Methods of Using FOXP3 Levels to Predict the Outcome of Organs Undergoing Acute Rejection |
| US9176122B2 (en) | 2008-03-24 | 2015-11-03 | University Of South Florida | Biomarkers for predicting response to immunosuppressive therapy |
| JP2013511554A (ja) | 2009-11-23 | 2013-04-04 | パラティン テクノロジーズ，インコーポレイテッド | メラノコルチン−１受容体特異的線状ペプチド |
| JP2014503217A (ja) * | 2010-12-31 | 2014-02-13 | ザ トラスティーズ オブ コロンビア ユニヴァーシティ イン ザ シティ オブ ニューヨーク | マウスにおける自己ｔ細胞の生成 |
| US8637038B2 (en) * | 2011-04-12 | 2014-01-28 | Rigel Pharmaceuticals, Inc. | Methods for inhibiting allograft rejection |
| WO2015056103A2 (en) * | 2013-10-15 | 2015-04-23 | Regeneron Pharmaceuticals, Inc. | High resolution allele identification |
| US12090142B2 (en) | 2018-02-22 | 2024-09-17 | Board Of Regents, The University Of Texas System | Combination therapy for the treatment of cancer |
| WO2020010067A1 (en) | 2018-07-06 | 2020-01-09 | Enzyvant Therapeutics, Inc. | Tissue potency determination through quantitative histomorphology analysis |
-
2019
- 2019-02-22 EP EP19757113.6A patent/EP3755346B1/en active Active
- 2019-02-22 AU AU2019225151A patent/AU2019225151B2/en active Active
- 2019-02-22 SG SG11202007498YA patent/SG11202007498YA/en unknown
- 2019-02-22 KR KR1020207023608A patent/KR102805282B1/ko active Active
- 2019-02-22 WO PCT/US2019/019137 patent/WO2019165197A1/en not_active Ceased
- 2019-02-22 CA CA3089593A patent/CA3089593A1/en active Pending
- 2019-02-22 BR BR112020016614-6A patent/BR112020016614A2/pt unknown
- 2019-02-22 KR KR1020257014739A patent/KR20250071282A/ko active Pending
- 2019-02-22 JP JP2020543913A patent/JP7499178B2/ja active Active
- 2019-02-22 MX MX2020008590A patent/MX2020008590A/es unknown
- 2019-02-22 CN CN201980013250.XA patent/CN112074277A/zh active Pending
- 2019-02-22 EP EP24216970.4A patent/EP4545145A3/en active Pending
-
2020
- 2020-08-13 IL IL276706A patent/IL276706A/en unknown
-
2021
- 2021-09-27 US US17/486,045 patent/US12064452B2/en active Active
-
2024
- 2024-01-17 JP JP2024005418A patent/JP2024041955A/ja active Pending
- 2024-07-08 US US18/766,244 patent/US20250114402A1/en active Pending
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