JP7499178B2 - 同種固形臓器移植に対するドナー特異的寛容を促進する培養胸腺組織移植 - Google Patents
同種固形臓器移植に対するドナー特異的寛容を促進する培養胸腺組織移植 Download PDFInfo
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- JP7499178B2 JP7499178B2 JP2020543913A JP2020543913A JP7499178B2 JP 7499178 B2 JP7499178 B2 JP 7499178B2 JP 2020543913 A JP2020543913 A JP 2020543913A JP 2020543913 A JP2020543913 A JP 2020543913A JP 7499178 B2 JP7499178 B2 JP 7499178B2
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024005418A JP2024041955A (ja) | 2018-02-23 | 2024-01-17 | 同種固形臓器移植に対するドナー特異的寛容を促進する培養胸腺組織移植 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862634377P | 2018-02-23 | 2018-02-23 | |
| US62/634,377 | 2018-02-23 | ||
| PCT/US2019/019137 WO2019165197A1 (en) | 2018-02-23 | 2019-02-22 | Cultured thymus tissue transplantation promotes donor-specific tolerance to allogeneic solid organ transplants |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024005418A Division JP2024041955A (ja) | 2018-02-23 | 2024-01-17 | 同種固形臓器移植に対するドナー特異的寛容を促進する培養胸腺組織移植 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021516224A JP2021516224A (ja) | 2021-07-01 |
| JP2021516224A5 JP2021516224A5 (https=) | 2022-01-31 |
| JPWO2019165197A5 JPWO2019165197A5 (https=) | 2022-01-31 |
| JP7499178B2 true JP7499178B2 (ja) | 2024-06-13 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020543913A Active JP7499178B2 (ja) | 2018-02-23 | 2019-02-22 | 同種固形臓器移植に対するドナー特異的寛容を促進する培養胸腺組織移植 |
| JP2024005418A Pending JP2024041955A (ja) | 2018-02-23 | 2024-01-17 | 同種固形臓器移植に対するドナー特異的寛容を促進する培養胸腺組織移植 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024005418A Pending JP2024041955A (ja) | 2018-02-23 | 2024-01-17 | 同種固形臓器移植に対するドナー特異的寛容を促進する培養胸腺組織移植 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US12064452B2 (https=) |
| EP (2) | EP3755346B1 (https=) |
| JP (2) | JP7499178B2 (https=) |
| KR (2) | KR102805282B1 (https=) |
| CN (1) | CN112074277A (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2021034650A1 (en) | 2019-08-19 | 2021-02-25 | Duke University & Medical Center | Methods of determining the suitability of cultured thymus tissue for implantation into humans and associated methods of use |
| CN115287262B (zh) * | 2022-01-28 | 2024-04-02 | 浙江中医药大学 | 一种胸腺类器官微球及其制备方法与应用 |
| WO2024042488A1 (en) | 2022-08-24 | 2024-02-29 | Enzyvant Therapeutics Gmbh | Thymic exosome assays, and methods of producing t cell depleted thymus tissue and uses thereof |
| WO2025068989A1 (en) | 2023-09-29 | 2025-04-03 | Enzyvant Therapeutics Gmbh | Device for cultivating and transporting biological tissue |
| JP7627920B1 (ja) | 2023-12-11 | 2025-02-07 | 浩 宮内 | 移植材料の評価方法 |
| CN118203653A (zh) * | 2024-02-06 | 2024-06-18 | 同济大学 | 一种利用胸腺疫苗降低或消除同种异体移植排斥的方法 |
| WO2025226936A1 (en) * | 2024-04-24 | 2025-10-30 | Revivicor, Inc. | Donor-specific tolerance-inducing regimens for xenotransplantation |
| WO2025240817A1 (en) * | 2024-05-17 | 2025-11-20 | The Trustees Of Columbia University In The City Of New York | Thymoliver and methods of constructing thereof |
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| ATE215375T1 (de) | 1992-01-08 | 2002-04-15 | Gen Hospital Corp | Induzierte toleranz gegen transplantate |
| US5658564A (en) | 1992-02-19 | 1997-08-19 | The General Hospital Corporation | Xenograft thymus |
| US6911220B1 (en) * | 1992-02-19 | 2005-06-28 | The General Hospital Corporation | Allogeneic and xenogeneic transplantation |
| US5876708A (en) | 1992-02-19 | 1999-03-02 | The General Hospital Corporation | Allogeneic and xenogeneic transplantation |
| US5766944A (en) * | 1996-12-31 | 1998-06-16 | Ruiz; Margaret Eileen | T cell differentiation of CD34+ stem cells in cultured thymic epithelial fragments |
| US20040096971A1 (en) * | 2000-12-22 | 2004-05-20 | Blackburn Catherine Clare | Thymic epithelial progenitor cells and uses thereof |
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| US20080131441A1 (en) | 2006-09-26 | 2008-06-05 | Manikkam Suthanthiran | Methods of Using FOXP3 Levels to Predict the Outcome of Organs Undergoing Acute Rejection |
| US9176122B2 (en) | 2008-03-24 | 2015-11-03 | University Of South Florida | Biomarkers for predicting response to immunosuppressive therapy |
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| AU2019225151B2 (en) | 2026-02-05 |
| AU2019225151A1 (en) | 2020-08-20 |
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| US20220079989A1 (en) | 2022-03-17 |
| BR112020016614A2 (pt) | 2020-12-22 |
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| MX2020008590A (es) | 2020-09-21 |
| EP4545145A2 (en) | 2025-04-30 |
| WO2019165197A1 (en) | 2019-08-29 |
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| SG11202007498YA (en) | 2020-09-29 |
| EP4545145A3 (en) | 2025-07-02 |
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| US20250114402A1 (en) | 2025-04-10 |
| KR20210005543A (ko) | 2021-01-14 |
| KR20250071282A (ko) | 2025-05-21 |
| EP3755346A1 (en) | 2020-12-30 |
| EP3755346A4 (en) | 2022-03-09 |
| RU2020124312A (ru) | 2022-03-23 |
| IL276706A (en) | 2020-09-30 |
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