SG11202007498YA - Cultured thymus tissue transplantation promotes donor-specific tolerance to allogeneic solid organ transplants - Google Patents

Cultured thymus tissue transplantation promotes donor-specific tolerance to allogeneic solid organ transplants

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Publication number
SG11202007498YA
SG11202007498YA SG11202007498YA SG11202007498YA SG11202007498YA SG 11202007498Y A SG11202007498Y A SG 11202007498YA SG 11202007498Y A SG11202007498Y A SG 11202007498YA SG 11202007498Y A SG11202007498Y A SG 11202007498YA SG 11202007498Y A SG11202007498Y A SG 11202007498YA
Authority
SG
Singapore
Prior art keywords
solid organ
organ transplants
tissue transplantation
specific tolerance
thymus tissue
Prior art date
Application number
SG11202007498YA
Other languages
English (en)
Inventor
Mary Louise Markert
Original Assignee
Duke Univ & Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duke Univ & Medical Center filed Critical Duke Univ & Medical Center
Publication of SG11202007498YA publication Critical patent/SG11202007498YA/en

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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/26—Lymph; Lymph nodes; Thymus; Spleen; Splenocytes; Thymocytes
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
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    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
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  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Wood Science & Technology (AREA)
  • Transplantation (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
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SG11202007498YA 2018-02-23 2019-02-22 Cultured thymus tissue transplantation promotes donor-specific tolerance to allogeneic solid organ transplants SG11202007498YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862634377P 2018-02-23 2018-02-23
PCT/US2019/019137 WO2019165197A1 (en) 2018-02-23 2019-02-22 Cultured thymus tissue transplantation promotes donor-specific tolerance to allogeneic solid organ transplants

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SG11202007498YA true SG11202007498YA (en) 2020-09-29

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SG11202007498YA SG11202007498YA (en) 2018-02-23 2019-02-22 Cultured thymus tissue transplantation promotes donor-specific tolerance to allogeneic solid organ transplants

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US (2) US12064452B2 (https=)
EP (2) EP3755346B1 (https=)
JP (2) JP7499178B2 (https=)
KR (2) KR102805282B1 (https=)
CN (1) CN112074277A (https=)
AU (1) AU2019225151B2 (https=)
BR (1) BR112020016614A2 (https=)
CA (1) CA3089593A1 (https=)
IL (1) IL276706A (https=)
MX (1) MX2020008590A (https=)
SG (1) SG11202007498YA (https=)
WO (1) WO2019165197A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021034650A1 (en) 2019-08-19 2021-02-25 Duke University & Medical Center Methods of determining the suitability of cultured thymus tissue for implantation into humans and associated methods of use
CN115287262B (zh) * 2022-01-28 2024-04-02 浙江中医药大学 一种胸腺类器官微球及其制备方法与应用
WO2024042488A1 (en) 2022-08-24 2024-02-29 Enzyvant Therapeutics Gmbh Thymic exosome assays, and methods of producing t cell depleted thymus tissue and uses thereof
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