JPWO2019089670A5 - - Google Patents

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Publication number
JPWO2019089670A5
JPWO2019089670A5 JP2020544334A JP2020544334A JPWO2019089670A5 JP WO2019089670 A5 JPWO2019089670 A5 JP WO2019089670A5 JP 2020544334 A JP2020544334 A JP 2020544334A JP 2020544334 A JP2020544334 A JP 2020544334A JP WO2019089670 A5 JPWO2019089670 A5 JP WO2019089670A5
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JP
Japan
Prior art keywords
cyclopropyl
vinyl
isoxazole
carboxylic acid
azabicyclo
Prior art date
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Application number
JP2020544334A
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English (en)
Japanese (ja)
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JP7264906B2 (ja
JP2021501805A (ja
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Priority claimed from PCT/US2018/058323 external-priority patent/WO2019089670A1/en
Publication of JP2021501805A publication Critical patent/JP2021501805A/ja
Publication of JPWO2019089670A5 publication Critical patent/JPWO2019089670A5/ja
Application granted granted Critical
Publication of JP7264906B2 publication Critical patent/JP7264906B2/ja
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JP2020544334A 2017-11-01 2018-10-31 ファルネソイドx受容体モジュレーターとしてのアルケン化合物 Active JP7264906B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762580060P 2017-11-01 2017-11-01
US62/580,060 2017-11-01
PCT/US2018/058323 WO2019089670A1 (en) 2017-11-01 2018-10-31 Alkene compounds as farnesoid x receptor modulators

Publications (3)

Publication Number Publication Date
JP2021501805A JP2021501805A (ja) 2021-01-21
JPWO2019089670A5 true JPWO2019089670A5 (ru) 2022-03-18
JP7264906B2 JP7264906B2 (ja) 2023-04-25

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ID=64332184

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020544334A Active JP7264906B2 (ja) 2017-11-01 2018-10-31 ファルネソイドx受容体モジュレーターとしてのアルケン化合物

Country Status (7)

Country Link
US (1) US11168079B2 (ru)
EP (1) EP3704106B1 (ru)
JP (1) JP7264906B2 (ru)
KR (1) KR20200081436A (ru)
CN (1) CN111511731B (ru)
ES (1) ES2944657T3 (ru)
WO (1) WO2019089670A1 (ru)

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CN110128432B (zh) 2018-02-02 2021-03-02 广东东阳光药业有限公司 含氮三环化合物及其在药物中的应用
KR20220034739A (ko) 2019-05-31 2022-03-18 이케나 온콜로지, 인코포레이티드 Tead 억제제 및 이의 용도
MX2021014443A (es) 2019-05-31 2022-01-06 Ikena Oncology Inc Inhibidores del dominio asociado mejorador de la transcripcion (tead) y usos de los mismos.
AU2021207253A1 (en) 2020-01-15 2022-06-09 Centre National De La Recherche Scientifique Use of FXR agonists for treating an infection by hepatitis D virus
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WO2022229302A1 (en) 2021-04-28 2022-11-03 Enyo Pharma Strong potentiation of tlr3 agonists effects using fxr agonists as a combined treatment
WO2023220404A1 (en) * 2022-05-13 2023-11-16 Terns Pharmaceuticals, Inc. Treatment of non-alcoholic steatohepatitis

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