JPS6146478B2 - - Google Patents

Info

Publication number
JPS6146478B2
JPS6146478B2 JP56157607A JP15760781A JPS6146478B2 JP S6146478 B2 JPS6146478 B2 JP S6146478B2 JP 56157607 A JP56157607 A JP 56157607A JP 15760781 A JP15760781 A JP 15760781A JP S6146478 B2 JPS6146478 B2 JP S6146478B2
Authority
JP
Japan
Prior art keywords
methyl
salts
formula
oxo
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP56157607A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5791989A (en
Inventor
Rainaa Rooranto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of JPS5791989A publication Critical patent/JPS5791989A/ja
Publication of JPS6146478B2 publication Critical patent/JPS6146478B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075—Two hetero atoms, in positions 3 and 5
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Saccharide Compounds (AREA)
JP56157607A 1980-10-06 1981-10-05 Acyl derivatives Granted JPS5791989A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH745080 1980-10-06

Publications (2)

Publication Number Publication Date
JPS5791989A JPS5791989A (en) 1982-06-08
JPS6146478B2 true JPS6146478B2 (index.php) 1986-10-14

Family

ID=4325316

Family Applications (3)

Application Number Title Priority Date Filing Date
JP56157607A Granted JPS5791989A (en) 1980-10-06 1981-10-05 Acyl derivatives
JP61018289A Granted JPS61178993A (ja) 1980-10-06 1986-01-31 アシル誘導体
JP2266152A Expired - Lifetime JPH0786112B2 (ja) 1980-10-06 1990-10-03 アシル誘導体

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP61018289A Granted JPS61178993A (ja) 1980-10-06 1986-01-31 アシル誘導体
JP2266152A Expired - Lifetime JPH0786112B2 (ja) 1980-10-06 1990-10-03 アシル誘導体

Country Status (21)

Country Link
US (3) US4412070A (index.php)
EP (1) EP0049499B1 (index.php)
JP (3) JPS5791989A (index.php)
KR (1) KR870000828B1 (index.php)
AT (1) ATE17729T1 (index.php)
AU (1) AU554552B2 (index.php)
CA (1) CA1168227A (index.php)
DE (1) DE3173642D1 (index.php)
DK (1) DK379581A (index.php)
ES (1) ES8206534A1 (index.php)
FI (1) FI73442C (index.php)
GR (1) GR75072B (index.php)
HU (1) HU185963B (index.php)
IE (1) IE51633B1 (index.php)
IL (1) IL63964A (index.php)
MC (1) MC1421A1 (index.php)
NO (2) NO813375L (index.php)
NZ (1) NZ198507A (index.php)
PH (1) PH20367A (index.php)
PT (1) PT73764B (index.php)
ZA (1) ZA816741B (index.php)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4695565A (en) * 1984-10-04 1987-09-22 Merck & Co., Inc. Antibacterial 7β-heterocyclic-cephem
EP0185220A3 (de) * 1984-12-19 1987-09-02 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Zwischenprodukte zur Herstellung von Cephalosporinen

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4348518A (en) * 1974-05-05 1982-09-07 Hoffmann-La Roche Inc. Cephalosporins
JPS6011713B2 (ja) * 1976-09-08 1985-03-27 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
JPS5444695A (en) * 1977-09-13 1979-04-09 Fujisawa Pharmaceut Co Ltd 3,7-disubstituted-3-cephem-4-carboxylic acid and its salt and their preparation
US4200745A (en) * 1977-12-20 1980-04-29 Eli Lilly And Company 7[2-(2-Aminothiazol-4-yl)-2-alkoxyimino]acetamido 3[4-alkyl-5-oxo-6-hydroxy-3,4 dihydro 1,2,4-triazin 3-yl]thio methyl cephalosporins
MC1259A1 (fr) * 1978-05-30 1980-01-14 Hoffmann La Roche Derives acyles
CH641468A5 (de) * 1978-05-30 1984-02-29 Hoffmann La Roche Cephemderivate.
NL8100089A (nl) * 1980-01-17 1981-08-17 Rhone Poulenc Ind Nieuwe thiolen en de bereiding daarvan.

Also Published As

Publication number Publication date
ES506022A0 (es) 1982-08-16
GR75072B (index.php) 1984-07-13
PH20367A (en) 1986-12-04
AU7574181A (en) 1982-04-22
FI73442B (fi) 1987-06-30
EP0049499A3 (en) 1983-09-07
DE3173642D1 (en) 1986-03-13
JPS61178993A (ja) 1986-08-11
DK379581A (da) 1982-04-07
IE812315L (en) 1982-04-06
FI73442C (fi) 1987-10-09
NO813375L (no) 1982-04-07
FI813088L (fi) 1982-04-07
CA1168227A (en) 1984-05-29
US4412070A (en) 1983-10-25
NZ198507A (en) 1985-02-28
ATE17729T1 (de) 1986-02-15
IE51633B1 (en) 1987-01-21
JPH03264591A (ja) 1991-11-25
IL63964A0 (en) 1981-12-31
HU185963B (en) 1985-04-28
KR870000828B1 (ko) 1987-04-23
JPH0786112B2 (ja) 1995-09-20
ES8206534A1 (es) 1982-08-16
KR830007691A (ko) 1983-11-04
EP0049499B1 (de) 1986-01-29
ZA816741B (en) 1982-09-29
IL63964A (en) 1984-12-31
MC1421A1 (fr) 1982-10-18
JPS5791989A (en) 1982-06-08
US4774330A (en) 1988-09-27
PT73764B (en) 1983-10-14
EP0049499A2 (de) 1982-04-14
US4520195A (en) 1985-05-28
NO822876L (no) 1982-04-07
PT73764A (en) 1981-11-01
JPH0333159B2 (index.php) 1991-05-16
AU554552B2 (en) 1986-08-28

Similar Documents

Publication Publication Date Title
FI65623C (fi) Foerfarande foer framstaellning av antibiotiskt aktiv (6r 7r)-3-karbamoyloximetyl-7-(2-(fur-2-yl)-2-metoxiiminoacetamido)-cef-3-em-4-karboxylsyra samt dennas icke-giftiga salter
EP0286145A2 (en) 3-Heterocyclylthiomethyl cephalosporins
JPS6145995B2 (index.php)
CY1182A (en) F 7-2-2-amino-4-hetrocyclylthiomethyl-cephems
BE897864A (fr) Procede de production de composes de 3-vinyl-3-cephem 7-substitues et nouveaux produits ainsi obtenus
GB2071654A (en) Hydroxamic acid derivatives of 7-(2-amino-4-thiazolyl)oximino cephalosporins
CS204957B2 (en) Method of producing novel 7-2-/4-thiazolyl/-2-iminoacetamido-3-/4-alkyl-5-oxo-6-hydroxy-4,5-dihydro-1,2,4-triazin-3-ylthio/methyl-3-cephemderivatives
US5055572A (en) Cephalosporin derivatives
JPH0242071A (ja) セレンアゾリル誘導体
EP0266060A2 (en) Cephalosporins, process for their preparation and pharmaceutical compositions containing them
CA1114808A (en) Derivatives of 7-¬substituted oxyiminoacetamido| cephalosporins
JPS6146478B2 (index.php)
CA1154009A (en) Cephalosporin derivatives
US4179502A (en) 7[2-Hydroxyiminoacetamido]cephalosporins
US4292428A (en) Cephalosporin derivatives
US4178443A (en) Derivatives of 7 [-substituted oxyimins acetamido] cephalosporins
CA1185599A (en) Cephalosporin derivatives
US4497811A (en) 1-Oxadethiacephalosporin compound and antibacterial agent containing the _same
US5306717A (en) Cephalosporin derivatives
EP0280521A2 (en) Cephalosporin compounds, process for their preparation and pharmaceutical compositions containing them
EP0098615B1 (en) 1-oxadethiacephalosporin compound and antibacterial agent containing the same
JPH06345775A (ja) セファロスポリン化合物、その製造法および中間体化合物
KR910007980B1 (ko) 신규 세팔로스포린계 항생제 및 이의 제조방법
KR910004334B1 (ko) 세팔로스포린 화합물
JPH0687865A (ja) 新規な１−オキサ−１−デチアセフエム化合物